Discovery Park:

A Paradigm for Interdisciplinary Research

A. H. Rebar, DVM, Ph.D.Executive Director of Discovery Park

andSenior Associate Vice President for Research

Discovery Park Integrated Centers

An ideal center will excel in five dimensions…

Quality

Economic development

Interdisciplinary

Leverage

Leadership

Burton D. Morgan Center for Entrepreneurship

Birck Nanotechnology Center

Gerald D. and Edna E. Mann Hall

Bindley Bioscience Center

Discovery Learning Center – to open 2009

Assoc. VPR & Dir. University Research Administration

Interim ProvostWilliam R. Woodson

Vice President for ResearchRichard O. Buckius

Sr. Assoc. VPR & Exec. Dir. of Discovery Park

Alan H. Rebar

Assoc. VPR Research Development & Research Support Infrastructure

OVPR/DP Business and Sponsored Programs Office

Dir. Sponsored Program Services

PresidentFrance A. Córdova

Founded 1961 2001

Purpose Start-up companies Interdisciplinary research

LocationOff-Campus

US 52 HighwayMain Campus

State Street

People 2878 employees ~1000 faculty members

# Buildings 38 4 completed; 1 broke ground Sept. 2006

# Companies/Centers 146 Companies 11 Centers

Area 591 acres 40 acres

2/15/08

Lilly Endowment support

Institutional support

Broad mission

Synergism among centers

• Bindley Bioscience Center• Birck Nanotechnology Center• Burton D. Morgan Center for

Entrepreneurship• Center for Advanced Manufacturing• Center for the Environment• Cyber Center• Discovery Learning Center• e-Enterprise Center• Energy Center• Oncological Sciences Center• Regenstrief Center for Healthcare

Engineering

Core Centers

Discovery Park Infrastructure• Administrative

– Business team – SPS & Business Admin.– Project coordination– Web site integration– Special events

• Technical– Research Cores – partnership with

academic units– Equipment and facilities

Project Based Centers

NSF Network for Computation Nanotechnology (NCN) Purdue Homeland Security Institute (PHSI)Purdue Climate Change Research Center (PCCRC)Purdue University Regional Visualization and Analytics Center (PURVAC)NEXTRANS (U.S. Dept. of Transportation Region 5 Transportation Center)Center for Catalytic Design (CCD)Product Life Cycle Management Center of ExcellenceCenter for Prediction of Reliability, Integrity and Survivability of Microsystems (PRISM) Center for Authentic Science Practice in Education (CASPiE)Center for Gene-Environment Interactions

Indiana Clinical and Translational Science Institute (CTSI)

Interdisciplinary in nature Affiliated with a core center

Sponsored programs Often opportunistic

New Initiatives• Center for Analytical Instrumentation Development

(CAID)

• Cytometry for Life (C4L)

• Center for Assistive Technologies

• DHS University Center of Excellence in Command, Control and Interoperability

• Purdue Institute of Defense Innovation

• Energy Frontier Research Centers

To Practice or Commercialization

Educational or Training Concepts

Purdue Research Park

Cooperative Education

Campus wide

Startup Company

Licensing

Joint Venture

Discovery Park is designed to rapidly integrate Purdue with outside partners.

An Engine for Indiana’s Economy

Value Proposition

Project Ideas

Seeding Nurturing Executing

Discovery Park & University Infrastructure

Industry

Alfred E. Mann Institute (AMI)at Purdue

• Alfred E. Mann is a successful entrepreneur in the medical device field.

• Created $1B+ non-profit Alfred E. Mann Foundation for Biomedical Engineering (AEMFBE)

• Mission is to expedite development of biomedical technologies at partner universities

• Endowing $100M+ non-profit Alfred E. Mann Institutes at partner universities (USC, Technion)

• Purdue is third partner site.

AMI Organizational Model• Operates under umbrella agreement with Purdue

Research Foundation (PRF) to expand our technology commercialization capacity

• Non-profit institute located in Purdue’s Discovery Park (DP)

• Governed by Board comprised of half Purdue and half AEMFBE selected members

• Uses ~$5M endowment income for all operational costs (e.g., rent, staff, resources)

AMI Organizational Model (cont.)

• Invests in and rapidly develops Purdue biomedical technologies

• Licenses developed technologies to companies (startup through established)

• Preference given to Indiana companies in order to fuel the local and regional economy

• Income is shared among inventors, PRF, AMI, AEMFBE

AMI Chief Advantages• AMI will complete analysis on:

– freedom to operate– barriers to market entry– time and cost to market– competitive technologies and market landscape– reimbursement strategies– regulatory approval processes– potential commercial partners

• Immediate resources will be brought to bear on projects developed by AMI

AMI Chief Advantages (cont.)

• Thus, technology will be subsequently licensed to a company when:– technical risk is significantly reduced:

• Working prototype(s)• Commercial scale demonstration• Preclinical and/or clinical studies completed• FDA approvals in process or granted

– market application is well-defined

• Result is a higher market value of the technology

Accomplishment: Sponsored Awards* ($M)

Purdue system wideDiscovery Park

5.513.4

26.7

27.6

44.0

54.2

68.4

2001-02 2002-03 2003-04 2004-05 2005-06 2006-07 thru' May2008

*Support in collaboration with Development is included. In addition, activity for awards to participating colleges/schools is included.

229.9 217.8243.4

294.3261.4

301.2

300

2001-02 2002-03 2003-04 2004-05 2005-06 2006-07 thru' May2008

Lilly End. 26

Lilly End. 25

# awards: 6 21 56 111 188 37743332 407632943256224 3131

thru’ May 2008

thru’ May 2008

3081210

Equipment $17,858,825

Office/Support Space Approx. 59,000 sq. ft.

Laboratory Space Approx. 102,000 sq. ft.

DP Accomplishment:Value Added Since August 2001

Start-Up Contributions $5,644,000Cost Shares 1,061,404

Equipment Grants 964,430Seeds Grants 3,709,661

Miscellaneous (e.g., summer grad support) 497,865TOTAL $11,877,360

*As of 2/2007. The total does not include costs of symposia, workshops, director salaries, administrative & business support for grant submissions, business plan competitions, Innovation Realization Laboratory/Technology Commercialization Laboratory, New Ventures Laboratory, CERIAS, EPICS Entrepreneurship Initiative, four endowed Directorships, DP Lectures Series, and other miscellaneous activities such as support of DP Research Cores in both personnel and equipment.

Funds from DP to Academic Units*

Seeding and Nurturing Start-up Companies1. Endocyte2. Griffin Analytical Technologies 3. 2K Corporation4. Biovitesse Inc.5. Tienta Sciences6. Indigo BioSystems7. Prosolia8. PriProTex*9. Quadraspec, Inc. 10. Data Tracking Solutions11. Theme Work Analytics** 12. Brogan Phamaceuticals13. Advanced Radiotherapeutic

Solutions*

14. VEM Smart Systems, LLC15. M4 Corporation16. MagSense Life Sciences17. MatrixBio, LLC18. Prima Specialty Vectors19. Stormfront Productions**20. Identity Alliance**21. Cytometry for Life**22. AlGalCo**23. Kylin Therapeutics, Inc.24. National Institute of

Pharmaceutical Technology

• Details of licensing are being worked out** Non Purdue Technology

Plus six start-ups by Interns for Indiana program students

• 5 new interdisciplinary research buildings

5 new interdisciplinary research buildings

• 3000 students in entrepreneurial activity

3000 students in entrepreneurial activity

• 500 faculty involved in interdisciplinary research

1000 faculty involved in interdisciplinary research

• $25 million/year in sponsored research funding

$44 million/year in sponsored research funding

• 8 new start-up companies20 new start-up companies facilitated in

cooperation w/Purdue Research Fdn.

• 20 corporate partners 20 corporate partners

In 2006, Discovery Park had:

Strategic PlanOctober 2003

(GE3NIE): Generating Entrepreneurs,

Entrepreneurial Ecosystems, and Networks for Indiana’s Economy:

A Discovery Park Super Project…in partnership with

– the Purdue Research Foundation– the Purdue Office of Engagement– and other organizations/institutions

…will develop and implement a series of programs– to enhance IP commercialization– to promote a culture of entrepreneurship

throughout the state

The outcome will be an Indiana Entrepreneurial Ecosystem.

National and International Partnerships

Signing of Memorandum of Understanding between Purdue University and the Department of Science and

Technology, Government of India

• Australia

• China

• India

• Israel

• Puerto Rico

• Korea

• Energy crisis

• Global warming

• Healthcare delivery

• Homeland security

• Learning

WOW by 2012 Building facilities for an additional

five core centers $100 million in annual sponsored

funding Thirty additional start-ups assisted

and facilitated Fifty new patent applications based

on Discovery Park research Ten new nationally recognized

project centers and institutes Twenty new partnerships with

global institutions

Video Clips

DP Overview

Biotechnology and Nanotechnology

Healthcare

It IS happening here!!

For information on Discovery Park: http://www.purdue.edu/discoverypark

Dr. A. H. Rebar, (765) 496-6625; rebar@purdue.edu