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7/27/2019 Disorders of Vascular Origin
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DISORDERS OF VASCULAR
ORIGIN
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PULMONARY EMBOLISM
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DEFINITION
..blockage in the
arteries of the lungs
from blood clots (usu.From legs)
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SYMPTOMS
Sudden dyspnea
Sharp chest pain (worse w/ cough &
deep breathe)
Cough w/ pink, foamy sputum
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SYMPTOMS (O)
Wheezing
Unilateral pedal edema
Cold cyanotic skin Excessive sweating
Tachycardia
Weak pulse
Lightheadedness
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CAUSE
DVT
Fracture
Tumor
Air bubbles
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RISK FACTORS
Prolonged immobility
Age
Family hx
Surgery
Medical conditions
Lifestyle
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DIAGNOSIS
CXR
Lung scan
CT Pulmonary angiogram
D-dimer blood test
UTZ
MRI
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MANAGEMENT
Meds
Anticoagulants Heparin & Warfarin
Thrombolytics Streptokinase
Surgery
Embolectomy
Vena cava filter
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PULMONARY HYPERTENSION
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DEFINITION
High blood pressure affects
arteries of the lungs & rightside of the heart;
narrowing or arteries
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SYMPTOMS
Dyspnea
Fatigue Syncope
Chest pain
Edema
Ascites Cyanosis
Palpitations
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CAUSES
IDIOPATHIC SECONDARY
Pulmonary emboli
COPD
Sleep apnea & disO
Congenital heart defects Sickle cell anemia
Cirrhosis
Cocaine, etc.
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RISK FACTORS
Idiopathic
Family hx
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DIAGNOSIS
Blood tests
CXR
Doppler ECG
Transesophageal ECG
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Right heart catheterization
Spirometry
Perfusion lung scan
CT
Open lung biopsy
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CLASSIFICATIONS
I: dx, x sx
II: x sx at rest, + N act.
III: comfy rest, + physical act.
IV: + at rest
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MANAGEMENT
Meds
Vasodilators: epoprostenol, iloprost
Endothelin receptor antagonist: bosentan
Sildenafil
High-dose Ca channel blocker: amlo, diltia, nife
Anticoagulants
Diuretics
O2 therapy
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MANAGEMENT
Surgery
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PULMONARY EDEMA
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DEFINITION
Excess fluid in the lungs
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SYMPTOMS
ACUTE
Dyspnea
Wheeze
Anxiety
Blood-tinged frothy
sputum
Excessive sweating
Pale skin
Chest pain
Palpitations
CHRONIC
Dyspnea when active
Orthopnea
Wheeze
Rapid wt. gain
Edema
Loss of appetite
Fatigue
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CAUSE
CAD
Cardiomyopathy
Heart valve probs HPN
Lung infxns
Exposure to toxins
Kidney dss
Smoking
Adverse drug rxn ARDS
High altitude
places
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DIAGNOSIS
CXR
ECG
Echocardiography
TEE
Pulmonary artery cath Cardiac cath
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MANAGEMENT
Preload reducers
Nitroglycerin
Diuretics Morphine
Afterload reducers
Vasodilators
BP meds