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DNA DNA STRUCTURESTRUCTURE
Where is DNA located?Where is DNA located?
Prokaryotic vs EukaryoticProkaryotic vs Eukaryotic
Johann FreidrichJohann Freidrich
MeisherMeisher1869
Isolated the first crude extract of DNA from white blood cells.
He called it nuclein.
Rosalind Rosalind Franklin & Franklin & Maurice Maurice WilkensWilkens1952
Used X-ray diffraction to understand the
physical structure of the DNA molecule
James James Watson & Watson & FrancisFrancis Crick Crick
1953
Formulated the correct double-helix
structure of the DNA molecule.
Double HelixDouble HelixIs the shape of the DNA molecule that looks like “twisted ladder structure.”
Made up of a backbone & complementary bases
BackboneBackboneMade up of sugar & phosphate molecules.
Complementary bases Complementary bases fit together based on fit together based on
shape.shape.
Thymine = Adenine
Cytosine = Guanine
NucleotideNucleotideMade up of one phosphate, one sugar, one nitrogen base
What macromolecule is made What macromolecule is made when nucleotides are put when nucleotides are put
together??together??
DNADNADNA is a nucleic acid!
Which one is human?Which one is human?
Which one is human?Which one is human?
All All living things have the same DNA living things have the same DNA STRUCTURE! STRUCTURE! (all DNA is made up of (all DNA is made up of
phosphates, sugar, & bases)phosphates, sugar, & bases)
Genetic Code depends on order of the Genetic Code depends on order of the bases.bases.
DNA > ChromosomesDNA > Chromosomes
DNA is wound up very tightly in the form of a chromosome. Chromosomes are located in the nucleus of the cell.
PRACTICE…..PRACTICE…..If one strand of DNA has the base sequence CCGATT, the bases on the other strand of DNA are: _________________________________
If one strand of DNA has the base sequence TAAGGCGATGC, the bases on the other strand of DNA are: _________________________________