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DnaTrek presentation at LLNL

Date post: 17-Jun-2015
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Six startups born out of Lawrence Livermore National Laboratory technologies made presentations at a recent entrepreneurial event to attract investors. The companies -- which have licensed technologies in biotech, renewable energy, sensors, infrared imaging and health care -- showcased their capabilities at the Entrepreneurs-in-Readiness (EIR) event at the Livermore Valley Open Campus' High Performance Computing Innovation Center. The event was part of an EIR program developed by the Lab's Industrial Partnerships Office (IPO) to connect nascent companies with entrepreneurs and investors. The idea is to engage a diverse group of entrepreneurs and industry experts from Silicon Valley to help nurture promising new early stage Lab technology companies toward commercialization. ipo.llnl.gov
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DNA Trek Confidential Slide - 1 Slide - ‹#› DNATREK develops traceability solutions to ensure the quality and safety of food, air and water resources Anthony Zografos, Ph.D [email protected]
Transcript
Page 1: DnaTrek presentation at LLNL

DNA Trek Confidential Slide - 1 Slide - ‹#›

DNATREK develops traceability solutions to ensure the quality and safety of food, air and water resources

Anthony Zografos, Ph.D

[email protected]

Page 2: DnaTrek presentation at LLNL

Slide - ‹#›

DNATraxTM: a versatile material

Biodetection

–Original Application

–Developed by LLNL under DoD funding;

–Pilot projects in progress

–“Low hanging fruit”

Food Traceability

–Great fit to technology

–Very small technical risk

–Huge opportunity in a growing market

Page 3: DnaTrek presentation at LLNL

Slide - ‹#›

1- Food Traceability: a huge opportunity

Cost of foodborne illnesses in the US: >$70 billion/yr

Cost of fraud to food industry: ~$15 billion/yr

Inability to quickly resolve food safety problems

–Frustrates the regulators

–Burdens producers with undue recall costs

–Tarnishes brands

–Undermines the public’s faith in the safety of the food supply

Page 4: DnaTrek presentation at LLNL

Slide - ‹#›

Traceability = Rapid Containment

Source of 2011 cantaloupe listeria outbreak was identified (per FDA) in RECORD time: 10 days

During that outbreak

–33 deaths

–150 hospitalizations

–Hundreds of millions in recall costs

–Cantaloupe industry has still not fully recovered

Page 5: DnaTrek presentation at LLNL

DNA Trek Confidential Slide - 5 Slide - ‹#›

DNATrax™

TRACE PRODUCE FROM FORK TO FARM IN MINUTES

<1 hr

4-6 weeks

?

?

? ?

Page 6: DnaTrek presentation at LLNL

Slide - ‹#›

The DNATrax™ Food Tracer

A safe and edible biological barcode

–Easily applied to produce at the source

Identifies in minutes product origin information down to field, crew, machine and date

Enables detection of

adulteration or fraud

in minutes

Italian Truffle: $1500/lb

Chinese Truffle: $20/lb

100 % λ?

75 % λ?

Page 7: DnaTrek presentation at LLNL

Slide - ‹#›

2 - Biodetection: Low hanging fruit

The bar to produce biological weapons is very low and getting lower

No safe way to in-situ test biodetection and filtration systems

Biodefense readiness at stake

Page 8: DnaTrek presentation at LLNL

Slide - ‹#›

The Solution: The DNATraxTM Biosimulant

Synthetic DNA with variable properties

Challenges detection and filtration systems in place

Safe for humans

Can simulate multiple sources and multiple threats in a single test

No clean up or decontamination necessary

Already approved for releases

Planned tests in NYC, SFO and Boston subways

Page 9: DnaTrek presentation at LLNL

Slide - ‹#›

DNATrax release at the Pentagon

“…As a result we have been able to make marked performance

improvements to the Pentagon’s biological detection system…”

Deputy Director of PFPA

Page 10: DnaTrek presentation at LLNL

Slide - ‹#›

Team

Anthony Zografos, Ph.D - CEO – COO CPAC (healthcare) - LLNL licensed technology

– Executive positions at four start-ups, Accuray, Applied Materials, KLA-Tencor

– Ph.D Mechanical Engineering, MBA

John Salony – Interim CFO – Consultant, RGP

– VP, Merrill Lynch Investment Banking

George Farquar, Ph.D – Inventor of DNATraxTM

– Currently Senior Scientist at LLNL

– Ph.D Physical Chemistry

Catherine Elizondo

– Business Development Executive at LLNL

Page 11: DnaTrek presentation at LLNL

Slide - ‹#›

Advisory Board

Jennifer McEntire, Ph.D

–Chief Science Officer, The Acheson Group

–Ran large pilot traceability program for FDA

Prof. Fotis Sotiropoulos

–Director, St. Anthony Falls Lab, Univ. of Minnesota

–Expert in aerodynamics and environmental monitoring

Garrett Patricio

–VP Ops and General Counsel, Westside Produce

–Cantaloupe Grower and Traceability Expert

Producer, 3rd Party Food Safety Director (pending confirmation)

Page 12: DnaTrek presentation at LLNL

Slide - ‹#›

Food Traceability a $14B Market Global Food Traceability Market: $14B

by 2020

Food marking technologies: $4B by 2017

Key Market Drivers

– Food Safety Modernization Act: requires traceability

–Increasing routine tests by FDA

–Legalization of marijuana

–Consumer sensitivity to food origin

–Major food fraud in China and India

High Risk and Premium: ~$1.4B

Food Traceability:

$14 B

Product Marking: $4 B

High Risk and

Premium: $1.4B

Page 13: DnaTrek presentation at LLNL

Slide - ‹#›

High

✗ ✗ ✗

DNATraxTM the fastest food source tracer

Harvestmark

QR

GS1 Lot

Barcode RFID

Speed of

traceback

Cost of

implementation

Applied to

individual items

Environmental

flexibility

DNATrax

✔ ✔

$600K $10-15K

1 hour 10-30 days <1 hour

High High

$200K

No No Yes

Low

1-7 days

No

✔ ✗ ≈

✗ ✗

$200K

Page 14: DnaTrek presentation at LLNL

Slide - ‹#›

Biodetection a $5.6B Market

Global biodetection market: $5.6B by 2017

Test and Evaluation: ~$1B

Market Drivers

–Proliferation of “how-to” for bio-agent production

–All US Navy ships equipped with biodetection networks by 2015

–BioWatch Gen-3 cancellation

U.S. “High Risk” segment (DoD, DoS): ~ 75M

Global Biodetection:

$5.6 B

Test & Evaluation: $1 B

U.S. High Risk: $75M

Page 15: DnaTrek presentation at LLNL

Slide - ‹#›

DNATraxTM the most versatile biosimulant

Tagged BT Gas Tracers

Indoor Use

Tunable

properties

Cleanup

needed

Multiple

sources, agents

DNATrax

✗ ✔

✔ ✗

✔ ✗ ≈

Urea Particles

Page 16: DnaTrek presentation at LLNL

Slide - ‹#›

Multiple Revenue Streams

Biodefense Revenue Stream

–Enrollment

–Equipment (release, sampling, analysis)

–Material Sales

Food Traceability Revenue Stream:

–Enrollment

–Annual Subscriptions

–Material Sales

–Analytical Services, primers, probes for QA and investigations

–Instruments (long term)

Page 17: DnaTrek presentation at LLNL

Slide - ‹#›

Food Market Strategy - SafeTracesTM

Secure FDA Support

–Safety (approval as food additive) - done

–Effectiveness (SBIR or other grant) – in progress

–Promote institutional Use (DNATrax in routine tests)

Innovators/Early Adopters

–Premium goods(truffles, olive oil, etc.); prevent adulteration, branding

–Large producers of high risk foods with good safety records: defend reputation, manage recalls

Partnership with Intertek Food Services – IFMS* *Integrated Food Management System

Page 18: DnaTrek presentation at LLNL

Slide - ‹#›

FDA Support

Inclusion of DNATrax in the routine FDA tests will be a key

adoption driver

Page 19: DnaTrek presentation at LLNL

Slide - ‹#›

Biodefense Market Strategy - DNATraxTM

Leverage LLNL ties into defense community

–Participate in 2015 subway tests – first material sale

–Pilot programs ( SBIR or other government grant)

Become biosimulant of record for US Navy

On-going advocacy to promote adoption

TECMIPT* Membership

–Recommends T&E standards across all DoD

*Test and Evaluation Capabilities and Methodologies Integrated Process Team

Page 20: DnaTrek presentation at LLNL

Slide - ‹#›

Financial Projections

Please contact company for detailed financial projections

Page 21: DnaTrek presentation at LLNL

Slide - ‹#›

Capital Raise

$ 1 million convertible note

Use of Funds

–Complete food additive registration (U.S., E.U.)

–Pilot program for 4-5 classes of produce

–Set up DNATrax pilot production

–Develop strategic partnerships

Page 22: DnaTrek presentation at LLNL

Slide - ‹#›

Future Raises

$1 million in 2016

–Exit Driver: Navy adoption

$3-$4 million in 2017

–Exit Driver: FDA “endorsement”

Page 23: DnaTrek presentation at LLNL

Slide - ‹#›

Exit Scenarios

Biodefense (Northrop-Grumman)

AgTech (Monsanto, Syngenta, DuPont, etc.)

Life Sciences (BioRad, Life Technologies, Cepheid, etc.)

Page 24: DnaTrek presentation at LLNL

Slide - ‹#›

Contact Information

Anthony Zografos, Ph.D

Founder and CEO

[email protected]

510-761-6782


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