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Do Now1. Get out your calendar & Karyotype HW, turn
in Karyotype Lab2. A woman carrying hemophilia marries a man
who is a hemophiliac. What percentage of their children will have hemophilia?
1. Cross a man heterozygous B with a woman who is a purebred for A. What blood types will their children have?
Albinism
Defect of melanin production that results in little or no color in the skin, hair, and eyes
Cystic FibrosisDisease that causes the body to produce unusually thick, sticky mucus that:
•Clogs the lungs and leads to
lung infections • Obstructs the pancreas
• Stops natural enzymes from helping the body break down and absorb food
Sickle Cell Anemia
Caused by an abnormal hemoglobin shape which causes the red blood cells to have a crescent shape.
Red blood cells carry oxygen.
Dominant Disorder
Caused by a dominant allele
Affected individuals are homozygous dominant or
heterozygous
Huntington’s Disease
Causes the break down of brain cells, (neurons) in certain areas of the brain.
Causes uncontrolled movements, loss of intellectual faculties, and emotional disturbance.
Do Now1. What are the genotypes for individuals
affected with the following disorders:a. Cystic Fibrosisb. Colorblindnessc. Huntington’s disease
2. A parent has a genotype Bb. What alleles can this parent give their children?
Types of Pedigrees: Recessive
Affected Genotypes: bb
Unaffected Genotypes: BB or Bb
HINT: Recessive Disorders skip generations
Types of Pedigrees: Sex-linked
Affected Genotypes: XbXb or XbY
Unaffected Genotypes: XBXB or XBXb and XBY
HINT: Mainly males are affected