DOH Cancer Programs• State Cancer Registry / FCDS• Biomedical Research Program Grants• Comp Cancer Control / CDC• Breast & Cervical Screening / CDC• Colorectal Cancer Screening• Lung Cancer Screening• Cancer Centers of Excellence• NCI CCC Designation Stimulus Funding
Florida Cancer Control & Resarch Advisory Council (CCRAB)• Write State Cancer Plan• Advise DOH on Cancer Programs• Commons area for advocacy
Florida Prostate Cancer Council• Educates clinicians• Educates public
1. Cancer in Florida
Florida’s Cancer Problem
• Large: 120,000 will be diagnosed with cancer this year.
• Lethal: 43,000 will die of cancer this year.
Florida Cancer GeographyAge-Adjusted Cancer Incidence Rates by County
130
135
140
145
150
155
160
165
170
2006 2007 2008 2009 2010 2011 2012 2013 2014 2015
Num
ber o
f Dea
ths
Due
to C
ance
r / 1
00,0
00 P
eopl
e in
Gen
eral
Pop
ulat
ion
Trend in Cancer Mortality Rate in Florida
1. Tobacco Prevention & Cessation2. Sun Safety3. Vaccinations: Human Papilloma Virus, HBV4. Cancer Screening: breast, cervical, colorectal, lung5. Supportive Care: antibiotics, blood tx6. Treatments: surgery, medicines, radiation, immuno-
oncology
MDS Cases Outside of State Cancer RegistryOutpatient Case Capture
Claims-Based
Myelodysplastic Syndromes cases
E-Path Reports
Cogle, et al. Leukemia Research 2014Cogle, et al. Blood 2011
Florida Cancer Data1. Increased investments in state cancer registry
infrastructure.2. Funded pilot studies of
• Claims-based case capture• Outpatient cases added• Veterans Affairs (VA) patients added• +100K cases discovered
• Capturing screening data• Capturing cancer biomarker data
• genetic data (somatic, germline, TIL)• Capturing patient outcomes
2. Cancer Control in Florida
ComprehensiveCancer Control
CancerRegistry
Cancer Center
Alliance - NCI
InvestigatorTobaccoResearch
InvestigatorCancer
Research
CancerScreening
CancerPrevention
OutstandingInvestigatorRecruitment
CancerHealth PolicyFellowships
Cancer New ProductDevelopment Research
Long-Term Vision of Cancer in Florida• Decreased cancer burden on Florida.• Reduced disparities in cancer incidence, mortality, and
access to care.• Deep scientific understanding of cancer biology & subclonal
evolution.• Strong Florida biomedical infrastructure of skilled and
collaborative cancer clinicians, researchers and facilities.
3. Cancer Trends in Florida
Florida Trend in Cancer Mortality 1999-2015
Florida Trends in Cancer Mortality 1999-2015
4. Florida versus U.S.
States by Cancer Deaths, GDP, and Cancer Research Dollars2015
5. Cancer Research Funding in FL
NIH Funding
Source: https://nexus.od.nih.gov/all/2016/05/31/how-many-researchers/
Florida Bankhead Coley Research ProgramState Funding for Cancer Research, Section 381.922, Florida
Statutes
0
50
100
150
200
250FY
06-
07
FY 0
7-08
FY 0
8-09
FY 0
9-10
FY 1
0-11
FY 1
1-12
FY 1
2-13
FY 1
3-14
FY 1
4-15
FY 1
5-16
FY 1
6-17
Applications
# Grants Awarded
$8.75 Millionfor 10 projects
in 2017
ROI10:1
Florida Bankhead Coley Research ProgramState Funding for Cancer Research, Section 381.922, Florida
Statutes
0
5
10
15
20
25
Num
ber o
f App
licat
ions 10-20 grant apps
per year
+ $20 millionper year
Unfunded Florida Cancer Research Proposals with No or Negligible Weaknesses
NA
6. Tobacco Omnipresent
Prevalence of Adult Smokers
Source: RWJF County Health Rankings
• Promote cessation of tobacco use• Prevent the initiation of tobacco use among
youth and adults• Eliminate secondhand smoke exposure• Reduce tobacco-related health disparities
7. Florida Cancer Plan Revision
Data Prevention &Screening
Improving Patient
OutcomesSurvivorship
Research, Workforce, & Commercial
Expand case capture Reduce tobacco use Health equity and access Cancer survivorship Invest in biomedical
research
Capture outcomes
Promote healthy lifestyles (obesity, HPV vaccine, UV,
radon)
Quality cancer care Quality of lifeBiomedical
workforce (K-12 & beyond)
Capture screening, laboratory, and molecular data
Increase cancer screenings Clinical trials End of life care Telehealth
Florida Cancer Plan2015 – 2020
Florida Regional Cancer Control Collaborative
Mission: Execute Florida Cancer Plan.
Florida Cancer Plan Revision2020 – 2025
September2018
CCRAB Planning
Kick-Off Meeting
December 2018
May2019
CCRAB Meetingwith facilitator
Community FeedbackKick-Off
July 2019
September2019
CCRAB Meetingwith facilitator
Implementation & Dissemination Plan
StakeholderFeedback
October 2019
February 2020
Publication
Christoph
Christopher R. Cogle, [email protected]
Bobbie McKee, Ph.D.External Board [email protected]
Source: Florida Population. (2018-01-19). Retrieved 2018-06-05, from http://worldpopulationreview.com/states/florida-population/
Florida Population Growth 1820-2020 Florida Age Distribution 2015
Jaiswal, et al. NEJM 2014Bejar, et al. Leukemia 2017
Circulating Blood with a Gene Mutation in5-10% of 60-90 year-olds
Complex
Simple
Invasive
Non-Invasive (ish)
1 5 M I L L I O N P A T I E N T S 4 , 1 0 0 P H Y S I C I A N P R O V I D E R S 1 , 2 4 0 P R A C T I C E S / C L I N I C S 2 2 H O S P I TA L S 6 7 C O U N T I E S
OneFlorida Clinical Research Consortium
University of Florida and UF Health
Florida State University and theRegional Campus Practice Partners
University of Miami and UHealth
Orlando Health
Florida Hospital
Tallahassee Memorial HealthCare
Health Choice Network
Bond Community Health Center Inc.
Nicklaus Children’s Hospital
CommunityHealth IT (WellFlorida Council)
Capital Health Plan
Partnering with Emory and Morehouse for All of US