Arthritis and Other AutoimmuneDiseases

Envision the internal workings of your body. See your heart pumping blood, pushing it through the more than10,000 miles of blood vessels each of us possess. See your lungs filling up with oxygen and exchanging it withthe carbon dioxide coming out of the "used" blood, and then pushing out the stale air. See your hundreds ofmuscles working together to produce the finest and most powerful of movements. See the digestion of foodsinto the building blocks and energy fuel for your marvelous body. See your body producing substances torepair and protect itself from foreign invaders.

When everything is perfectly timed, all parts working in unison toward the same goal, you have a description ofhealth.

However, with autoimmune diseases, something goes wrong, causing the body to work overtime, and in thewrong direction or in two directions at once.

Autoimmune disorders exist when a person's body produces abnormal cells or anti-nuclear antibodies (ANA)which, instead of attacking the legitimate infectious, viral invaders, and mutated cells of the body, turn andattack aspects of the healthy body itself. ANA cells, once they have become wrongly educated, do notrecognize healthy cells, tissues and organs as such, and will attack them as though they were invaders. Aperson's immune system becomes confused, poorly defending against outside invading agents, while attackinghealthy tissues and organs.

This is a problem with the memory T-cells of the immune system. So it stands to reason that any remedy thatdoes not address the defect in the memory T-cells, but rather only addresses the symptoms caused by theproblem, will not work. These symtom remedies may make you feel somewhat better temporarily, but they willnot bring you out of the condition.

There are many people living with autoimmune diseases and the numbers are increasing quickly. Autoimmunediseases take many forms:

Multiple Sclerosis is present when the immune system attacks the nerve tissues of the central nervoussystem, destroying the myelin sheath. This usually causes severe disability - blindness, paralysis, andearly death.

Rheumatoid Arthritis exists when joint linings are directly affected, causing pain, swelling and stiffnessand sometimes severe malformation of the joints.

Inflammatory Bowel Disease (such as Crohn's and Ulcerative Colitis) results when the immune systemattacks the intestinal areas, causing pain, diarrhea, nausea, and abdominal cramps.

Systemic Lupus Erythematosus usually exhibits itself with extreme fatigue, rashes and joint pain. A rashon the cheeks across the bridge of the nose is very common. Major organs may also be affected,causing severe problems for the kidneys, brain, or lungs.

Psoriasis (and some other skin disorders) affect the skin and sometimes the eyes, nails, and joints.

Scleroderma exists when the skin and blood vessels begin to thicken. Raynaud's Syndrome (severe coldin fingers and toes) is often also present. Symptoms may include sensitivity of fingers and toes to thecold, skin color changes, pain, and sometimes ulcers of the fingertips or toes.

Fibromyalgia symptoms includes severe fatigue, overall body aches and pains, sleep disorders, stiffness

of body joints, headaches, memory and concentration problems, fluid retention, intestinal problems, andother mixed symptoms. There are usually several "tender points" scattered throughout the body which,when pressure is applied, can cause a person very severe pain, even causing them to double over.

Sjogren's Syndrome is a condition affecting the body's fluid-producing glands. These glands reduce theirfluid output and eventually run dry, causing a person to suffer from dry eyes, dry mouth, and dry skin.Sometimes sore and aching muscles, extreme fatigue, and other autoimmune and connective tissuediseases will develop.

Diabetes - Some diabetes is caused by an autoimmune attack on the islet cells of the pancreas reducingthe quantity of insulin released into the blood.

ALS (Lou Gehrig's Disease) and AIDS are both massive autoimmune diseases that eventually destroythe entire body.

What is common with all these diseases is that they have the same cause. There are other factors that modifythe effects of the disease, but the cause is the same. In all forms of treatment expediency is a must. If you havean autoimmune disease, you don't want to wait even one more day before you do something about it. The keyis to do the right thing.

The Autoimmune Process

The general health of a person and any essential nutrient deficiency is going to play a role in all of thisprocess.

All cells of the immune system are derived from stem cells in bone marrow. The bone marrow is the origin ofred blood cells, white cells (including lymphocytes and macrophages), and platelets. In the thymus glandlymphoid cells undergo a process of maturation and education prior to release into the circulation. Thisprocess allows the lymphocyte T-cells to develop the important attribute known as self-tolerance. That is, theT-cells are learning to recognize and tolerate "self," meaning any cells that are a normal part of your body!

The thymus gland is a place where a potential problem can develop with memory T-cells.

Injuries, infections, and wear can affect the condition of our bodies. An injury could be a fall, an automobilecrash, or a sports injury. An infection can be rheumatic fever or any virus or bacteria, or it could come from aninternal parasite. Wear can come from being overweight, overwork from sports such as tennis, basketball, orgolf, or it can be job related, such as excessive use of keyboards or jackhammers. The twisting of a knee onetime can cause arthritis to develop many years later, even after the injury is completely healed!

The injury, infection, or wear can cause some small part of the body to dislodge, perhaps the myelinsurrounding the nerve or perhaps some cartiledge from a joint. And this is where the process starts. The whiteblood cells known as macrophages play a function in immunity by surrounding, ingesting, and destroyinginvading bacteria and other foreign organisms in a process called phagocytosis ("cell eating"), which is part ofthe inflammatory reaction. These macrophages consume the broken off particles and report their activities tothe memory T-cells!

The dormant memory T-cells activate and develop an aggressive cleanup program. If the memory T-cells do notdistinguish between healthy and damaged tissue, as the increased T-cell activity stimulates more macrophageactivity which in turn stimulates more memory T-cell activity, the process of self destruction has begun.

It can take many years before any noticeable effects are felt. The initiating factor, the injury, infection, or wearmay have disappeared long ago. There may be no evidence of a degenerative disease because not enoughmaterial has been destroyed by this process to show any symptoms. Arthritis sets in, almost in every casesome ten years after an injury or surgery. Because it gradually happens over a long period, people tend toignore it until it becomes unbearable.

But once you become aware of what's happening, waiting is the worst thing you can do! Why should you letyourself deteriorate more before you decide to do something about it? That would be like letting your houseburn down some more before you put out the fire. The only intelligent way is to stop it as soon as possible.You can buy a new house, but you can't buy a new body.

An autoimmune disease is self-propagating. It does not depend on the initiating factor to keep it going. Theinitiating factor may have healed completely a long time ago, but the auto-immune process, once set in motion,keeps going.

The process is exacerbated by the fact that the mechanism that is supposed to deactivate the memory T-cellswhen they have completed their mission fails to respond or work properly. So there are an abundance ofmemory T-cells directing the macrophages to search the body for more material to consume. The immunesystem is totally out of control, massive destruction begins, and the symptoms of pain and inflammationappear.

The destruction accelerates. Symptoms become more severe. In arthritis for example, pain, inflammation, andjoint deformity appear at new sites as they suffer macrophage attacks. Medications may take away the paintemporarily but they can't stop the body's process. The body is just doing what it thinks it should be doing. Buteven natural ways of dealing with the pain and inflammation do not stop the process, because strengtheningthe immune system can actually strengthen the disease. Conventional medications take their toll on thekidneys, liver, and heart, and do not stop the process. Products, natural or conventional, that treat thesymptoms of an autoimmune disease effectively deceive you because the deterioration is continuing eventhough you don't feel it anymore. This is like cutting the wire to a warning light on the dashboard of your car,rather than fixing the problem that is activating the light in the first place.

The more knowledgeable modern physicians in recent years used products called immunomodulators tocorrect the autoimmune problem. The only problem was the immunomodulators were not trueimmunomodulators. What they really were were immunostimulants or immunosuppressants. These natural orsynthetic substances can produce onlyone effect each, either stimulate or suppress the immune system. A trueimmunomodulator would have the ability to correct the defect in the memory T-cells!

If you use immunostimulants or immunosuppressants as part of your autoimmune plan you will have to usethem until the day you die. If you are at the early stages they may seem to cure the disease because they takecare of the symptoms. That is the deception.

There are some true immunomodulators. Some are manufactured and some occur in nature. It is always betterto use the natural substances. For example: colostrum and spirulina both contain natural immunomodulators.

Arthritis and Autoimmune Disorders

Do you suffer with arthritis or any other autoimmune disorder? Have you learned to "live with it?" Have youbeen told there is nothing you can do about it? Do you believe it?

Autoimmune diseases cannot be cured with drugs. But ask yourself, "Is it possible that my body could healitself of this disorder if my body was supplied with every nutrient it needed so that its systems could functionproperly?" There are a lot of scientific and biological studies that indicate the answer is yes.

Don't resign yourself to failure, even though you have tried many things that have failed. There are new, naturalsubstances that are continually being discovered (not created). Yes, it can be painful to keep trying. Havingyour hopes dashed again and again can be the most painful thing of all. But one thing for sure, if you quittrying, you will never succeed!

Excerpt reprinted from a memo released by Dr. Len Sands, Director of the San Diego InternationalImmunological Center

The Arthritis Process Step-By-Step with CMOT Intervention

1. Infection, trauma, or excessive wear affects some joints. (Usual infections are rheumatic fever, flu, orbacteria. Traumas include auto wrecks, falls, sports injuries, etc. Excessive joint wear comes from beingoverweight, or from repetitive stress such athletic exertion, use of keyboards, jackhammers, etc.)

2. #1 causes damaged or infected cartilage particles to become dislodged. This happens regardless ofwhether it's "osteo" or "rheumatoid" or "reactive" arthritis.

3. Macrophages of the immune system begin cleanup of dislodged cartilage particles.

4. Macrophages report their activities to dormant memory T-cells (m/T-cells).

5. Dormant m/T-cells programs activate and develop aggressive anti-cartilage cleanup programs, whichdo not distinguish between healthy and damaged cartilage.

6. The m/T-cells programs stimulate more macrophage activity, which in turn activates even moredormant m/T-cells.

7. Increased m/T-cell population stimulates even more macrophage activity, and the self-perpetuatingcycle of cartilage destruction expands. Because m/T-cell programs don't limit macrophage activity todamaged cartilage only, destruction of healthy cartilage also occurs. It has developed into a destructiveautoimmune syndrome. But, until sufficient cartilage has been destroyed, symptoms are not evident. Theinitiating factor (infection, trauma, or wear) may have disappeard months or even years ago, but thedestructive autoimmune process remains active. It is self-perpetuating and no longer dependent upon theinitiating factor.

8. The cycle is compounded by the fact that the mechanism which should deactivate certain m/T-cells(those that have completed their mission) fails to function, because the constant restimulation of the m/T-cells keeps them active. So now there is an overabundance of m/T-cells propelling macrophage cartilagedestruction. The immune system is totally out of control and massive cartilage destruction begins. Earlysymptoms of pain and inflammation appear.

9. Cartilage destruction accelerates. The cycle reaches critical mass. Macrophages are now scouring thebody to find and destroy any cartilage anywhere it can be found. Symptoms become more severe. Pain,inflammation, and joint deformity appear at new sites as they suffer macrophage attacks.

10. Symptoms of pain, stiffness, swelling, nodules, and deformation often reach intolerable and cripplinglevels - especially as joint cartilage disappears and bone-on-bone erosion occurs. Conventional arthritismedications take their toll on the liver, kidneys, and heart. Normal life span is often shortened by up toten or twenty years from both the ravages of arthritis and side effects of medications used.

INTERVENTION (the sooner the better) with CMO™can stop the autoimmune processat any point.

Dr. Len Sands, PhD, now deceased, was the clinic director of the San Diego Immunological Center and theauthor of the books Arthritis Defeated at Last - the REAL Arthritis Cure and Arthritis Beaten Today, whichhave been translated into five languages so far, including Chinese.

After ten years working on classified government projects, Dr. Sands began his direct active participation inclinical matters in 1970, as an associate of Manhattan Fifth Avenue Clinic in New York City. Within the next fouryears, he opened and became the owner and director of six medical clinics, as well as acquiring SouthlandGeneral Hospital in Texas. Later, he opened two medical clinics in Mexico. He became involved in medicalresearch projects concerning autoimmune diseases, viral diseases, diabetes, and cancer.

By the mid-1980s, he was thoroughly disillusioned by the limitations of conventional medicine and spent thenext ten years traveling the world researching innovative therapies involving both conventional and alternativemedicines, especially seeking those which were documented by exacting clinical trials in the major Europeancountries. He also explored many unconventional as well as documented therapies in various Asian, MiddleEastern, Latin American, and Oceanic countries.

As clinical director of the San Diego Immunological Center, he encouraged his researchers and medical staff tospecialize in what he calls "curing the incurable" - diseases for which convetional medicine offers no hope ofremedy.

Curing the Incurable was the title of a one-hour interactive weekly radio program Dr. Sands hosted in 1997.

Early in his career, he produced scientific and marketing material for industrial corporations, as well as forParke-Davis and the pharmaceutical division of the Dow Chemical Company and others.

It was Dr. Sands' own bone-grinding arthritis that prompted him to relentlessly prod his research associates intofinally finding a lasting cure for arthritis. The research resulted in the development of the world's first and onlytrue immunomodulator, a naturally occurring substance that should impact the course of medical history, butprobably won't since it is not a patented medicine. However, it certainly is changing the way autoimmunediseases will be addressed in the future.

That discovery, CMOT (cerasomal-cis-9-cetylmyristoleate) in 1995, is proving to be of great value for numerousother incurable diseases with strong autoimmune factors, like multiple sclerosis, fibromyalgia, lupus, ALS (LouGehrig's Disease), emphysema, Crohn's disease, scleroderma, sarcoidosis, and myasthenia gravis, amongothers. It is also relieving or curing ankylosing spondylitis, psoriasis, carpal tunnel syndrome, prostateinflammation, Sjogren's syndrome, TMJ, Behcet's syndrome, macular degeneration, Reiter's syndrome, sciatica,tendonitis, and more - all of which have strong autoimmune components.

CMOT is now being used to treat autoimmune diseases on every continent in the world. As its phenomenalsuccess with these diseases uncovers more options, the research goes on. Nothing would have pleased Dr.Sands more, including the continuing research and clinical studies on even more diverse incurable diseases.

Therapies using CMOT combined with the proper supportive nutritional products and proper diet for a minimumof the first 30 days have been proven to be beneficial for all autoimmune diseases like those mentioned above,plus muscular dystrophy, chronic fatigue syndrome, Alzheimer's, Parkinson's, Raynaud's, hypertension, andheart and vascular diseases, as well as ridding the body of conditions caused by environmental, dentalamalgam, medicinal, chemical, metallic, and other toxins.

CMOT is the world's first and only true adaptogenic autoimmune immunomodulator product.

CMOT is not an immunosuppressant or an immunostimulant. CMOT is considered "adaptogenic", meaning: it iscapable of altering the course of a disease in a positive direction, because of its corrective and restorativeimmunomodulatory properites for autoimmune diseases and inflammatory processes. Other so-called"immunomodulators" are not true immunomodulators. They function as immunosuppressants orimmunostimulants. They are capable of one principle action, either temporarily suppressing or stimulatingimmune function, not correcting or restoring it. CMOT, on the other hand, permanently corrects theprogrammed autoimmune attacks controlled by the memory T-cell (m/T-cells) themselves. That is why a single30-day CMOT therapy program of three 90 caplsule bottles (270 caplets) (3 capsules, 3 times a day) ordinarilylasts indefinitely without any need to repeat the therapy or use any additional medications of any kind thereafter.

Some practitioners have theorized that, in the case of arthritis for example, CMOT merely acts upon painreceptors at the arthritic site. It that were so, their theory cannot explain why CMOT has the following effects:

It benefits virtually any and all ailments associated with autoimmune diseases. It lowers blood sedimentation in lupus patients. It relieves certain symptoms of multiple sclerosis.It reverses lung inflammation in emphsema.It lowers the need for insulin in diabetics.

It reverses prostate inflammation.It corrects Crohn's disease.It reverses fibromyalgia.It improves the health of ALS (Lou Gehrig's Disease) patients.It lowers high blood pressure, yet elevates low blood pressure.

CMOT is a general remedial immunomodulator that acts upon the memory T-cells, which control theautoimmune processes within our bodies. It is also important to understand the CMOT acts only upon memoryT-cells and does not inhibit the activities of any of the several other types of T-cells that are responsible forcombating infective microorganisms or invading substances. Unlike the immunosuppressants commonly used totry to temporarily control the symptoms of autoimmune diseases, CMOT does not leave the body vulnerable toattack by disease-causing agents. Neither does it inhibit the body's resistance to tumor formation, as do thedangerous new tumor necrosis factor (TNF) suppressants of some new arthritis drugs.

Authentic CMOT, as reasearched and developed by the San Diego Immunological Center is the primaryingredient of Dr. Jeff's Joint Health™

Click here for Dr. Jeff's Joint Health™

Dr. Jeff's Joint HealthT which combines CMOT and MSM was developed using the combined research of Dr.Sands, Dr. Grange, Dr. Bennert, and a host of other professionals, who collectively believe this is the mosteffective combination of ingredients available on the market today to combat and prevent autoimmunedisfunctions. It is important to follow the directions. Take 3 bottles, 90 count each, totalling 270 caplets for thefirst 30 days, three upon waking, one hour before eating, three one hour before lunch, and three before dinner.Dr. Jeff's Joint CreamT will help for immediate pain and dull aches. For full effectiveness follow therecommended diet, and on an ongoing basis supplement Dr. Jeff's Joint HealthT by drinking at least 11/2 quarts of Marine Bio Coral Calcium (scroll down the products list to "Sango Coral Calcium") treateddistilled water daily and taking digestive enzymes RBC's Digestion Formula (Scroll down the list to"Digestion Formula"), Omega 3 Oil RBC's IQ (Scroll down the list to "I.Q."), anti-oxidants RBC'sMicrohydrin Plus (Scroll down the products list to "Microhydrin Plus") and Dr. Jeff's BioPro with SBOs(soil-based organisms).

After your condition is reversed, to maintain your health on a monthly basis, we recommend one bottle of Dr.Jeff's Joint HealthT and a monthly supply of the other support ingredients mentioned above.

The San Diego International Immunological Center (SDC) is a research and treatment facility and does not sellor benefit from the sale of CMOT or any other product. We do, of course, dispense CMOT and the supportingnutritionals to subjects enrolled in our studies and to clinic patients who may be part of our diagnosis andtreatment programs. CMOT counterfeiters seem to show up every week. Most are hit and run artists and quicklydisappear. CMOT is made in 6%, 11%, 40%, 50%, 80%, and 100%. It is difficult and confusing to know if youhave found the real 100% authentic CMOT source or some ineffectivbe imitation.

The reliable sourse for authentic CMOT is Dr. Jeff's Joint HealthT and Dr. Jeff's Joint CreamT Use the"Products" link on the upper left of this page or the links within this article to find these products.

NOTE: This document is supplied for information and educational purposes only. It is not intended torecommend or prescribe any treatment for any condition or illness. Contact a doctor or medical professional whois trained in natural nutritional supplements before adding any new protocol or when starting any health orexercise program.

© Dr. Len Sands. All rights reserved

Click here forArthritis Studies

It is important to recognize that CMO+ is the firstproduct of its kind in history.

The first dietary joint supplement to guarantee results after 10days of use. That is what makes CMO+ so very special.CMO+ is a truly important discovery and it may well revolutionizejoint health worldwide, using only dietary supplements. Naturalproducts are slow to be applauded in the world of healthcare.When this one becomes as well known as vitamin C or babypowder, we won't be able to keep up with the demand.

The discovery of cetylmyristoleateThe effect of cetylmyristoleate onjoints was discovered by U.S.NationalInstitutes of Health chemist H. W. Diehland an article describing its discoverywas published in Journal ofPharmaceutical Sciences [83(3):296-298]. Cetylmyristoleate, however, hadto be injected to be effective. Like other liquid waxes it iscomposed of large molecules that tend on clumping togetherforming large impenetrable masses which resists absorption andpass through the digestive system virtually undigested.

Making the indigestible digestibleAware of the great potential of the substance, the San DiegoClinic Immunological Center under Dr. Len Sands, invented anexclusive way to change the liquid was into a waxy solid namedcerasomal-cis-9-cetylmyristoleate (CMO). As a solid, CMOhas a crystalline structure that shatters in the alkalineenvironment of the small intestine forming a mesh of smallparticles that is readily absorbed and digested by the intestines.The exclusive process is responsible for CMO's greaterbioavailability and efficacy.

Making the digestible even more digestibleFor several years, companies have advised users to take amixture of digestive enzymes along with the CMO to make iteven more digestible. Nutritional Health Services has incorporated2 lipase enzymes into each CMO+ capsule. To the best of ourknowledge, CMO+ is the first and only CMO supplement tocontain these two enzymes which are specific in amount andtype for optimal digestion of the content of each CMO+ capsule.The built-in enzymes increase both the absorption and theefficacy of CMO+.

Products to look out for:

Cetylmyristate: Without the "oleate", signifying a salt ofoleic acid, the compound is incapable of supporting thenatural functions of joints. While these products are cheapand may retail for $3 or $4 a bottle wholesale, they areworthless as joint supplements.

Vegetable sources: Beware ofproducts that claim to be"cetylmyristoleates" from"vegetable sources". In order to

make any form of myristoleate,including cetylmyristoleate, youhave to start with myristoleicacid. The biochemist's bibleBaily's Industrial Oil and FatProducts 5th Edition, lists onlyfour sources for myristoleic acid,namely beef tallow, butter fat,chicken fat, and sheep tallow.There are no vegetable sources.Any claim that cetylmyristoleate came from a vegetablesource -- including coconut oil or soybean oil -- isfraudulent.

Watch out for dangerous synthetics: Syntheticcetylmyristoleate is not the same as naturalcetylmyristoleate. The structure of the synthetic moleculesis different. Roughly half of the synthetic molecules arewhat is known as 'trans' molecules (as opposed to 'cis'molecules). The trans molecules are unnatural to thebody and cause physical damage by disrupting cellmembranes. Because CMO+ is an all-natural product, itcontains absolutely no trans molecules. The word 'cis'in cerasomal-cis-9-cetylmyristoleate is your assurance thatCMO+ is 100% free of the unnatural, harmful transmolecules found in all of the synthetics.

Friday, November22, 2013

We realize that those who do not respond well to CMO+ do notwrite to say so. They simple request a refund. This is true of 8-10 % of our customers. Therefore it is important for you tounderstand that the grateful CMO+ users who wrote thesetestimonials represent the remaining 90 -92% of our customers.One way or another, we guarantee you'll be happy with ourcompany. Good results speak for themselves. Customers whofeel they did not receive beneficial results, although disappointedwith our product, are happy to receive a refund.

What determines who can get a refund? We believe people arehonest and would not ask for money back if they benefited fromour products. Therefore, all you have to do is request a refundin writing, either e-mail or snail mail. Do wait at least 30 daysafter finishing the capsules before requesting a refund if youneed one. Beneficial results are sometimes subtle at first andmay be slow to appear. However, for most, the improvementcontinues for months and results are usually very long lasting.All bodies repair at different rates.

Date: Sun, 17 Jun 2003 23:02:26 EDTFrom: Audrey Travis.Dear Marge,I've used CMO a couple of years ago, and I must say I am a true believer. I nolonger have the pain in my neck or feet and the ugly knots and swollen joints aregone. I tell everyone I know that suffers from the same kind of pain about mywonderful results. Thank you!Audrey Travis (Texas)

From: Wendy Thronburg <wmhs@trib.com>To: Marge Berger <info@bestcmo.com>Sent: Monday, February 05, 2003 01:46 PMSubject: Re: SarcoidosisHi Marge!I wasn't sure the CMO would work for Steve, but it did! He has given me permissionto write you his testimonial.

In October of 2000, my boyfriend Steve Wiecki (from Thermopolis, WY) was giventhe temporary diagnosis of Sarcoidosis. He was given anti-inflammatory drugs andpain medication, and was told to return in about 5 weeks for a check-up, and toreturn sooner if symptoms got worse. Well, he gradually showed a decline in hishealth and eventually, in December had to return. At that time, he was referred to aPulmonologist. He met with the doctor and found out that he had to have a biopsydone. There was concern about if it was cancer, or indeed Sarcoidosis. Well, thebiopsy went well and it was determined that he did have Sarcoidosis.

At the time, it was affecting his lymph nodes and breathing. He had lost 20 lbs., haddifficulty eating, swallowing, and his overall health was declining. He used to liftweights and was very physically fit and in a matter of months felt tired, was weak,and felt very ill. When he was in the hospital for the biopsy, I began doing moreresearch on alternative methods to treat Sarcoidosis. The information that I had read

on steroids was troubling and I just didn't want him to have to go through that.

I discovered your web-page on CMO+ and I felt like it was an answered prayer!Steve was not only struggling with his health, but having no medical insurancethrough where he works, he was paying for all medical expenses himself. He feltterrible, and he was discouraged and depressed regarding his circumstances. Iprinted the information from your web-page and discussed it with him. After awhile,we decided that it would be something worth trying. His attitude was that it couldn'thurt and that if it didn't work, he would just have to take the steroids.

Well...after day 3 of taking the CMO+, he started feeling better. He could breatheagain without pain! He continued for the entire 10 days and I am sooooo happy toreport that he feels great! He is eating again, he can swallow, he can breathe, hehas no chest pain, etc. All of his symptoms are gone! I am praying that the resultsare lasting, but if they aren't, we know where to go to get more! Thank you for yourproduct...it has been a blessing! I have given your product information to severalpeople that have arthritis and Crohn's that I know and I am encouraging them to tryit.

Steve is a walking testimonial and all that know him have seen the incredible results.Thank You Again-Wendy Thronburg, (Worland, WY)

Date: Fri, 12 Jan 2003 14:08:28 -0800Subject: CMOFrom: Mark Howell howell@harmonyexchange.comTo: info@bestcmo.comHello Marge,In September of '00 I was diagnosed with Sarcoidosis. This diagnosis was finallyachieved after a year's worth of terrible symptoms & many, many tests. Thismysterious disease can attack the body in so many different ways and fromeverything I learned during this ordeal, the medical community has only scratchedthe surface in understanding this illness. The current trends are to treat the diseasewith drugs such as Prednisone or Methatrexate and I, personally, was too worriedabout the side effects of those drugs to go that route. I don't want to discourageothers from taking those drugs but I wanted to explore other options for myselfbefore I made that decision.

While on the internet I happened upon your site. I was very skeptical but intrigued byyour information and I decided that I had nothing to lose by giving it a try. I am gladthat I overcame my skepticism and ordered the product. I noticed an improvement inmy symptoms within 3-4 weeks after starting the product. One of the major problemsI had was a grossly enlarged spleen, 4-5 times normal size. I noticed a reduction inthe size of my spleen and when I commented about this to my doctor he did anexamination and was surprised at the difference. It is still enlarged but seems to beshrinking daily.

I had experienced extreme, debilitating fatigue during the course of the illness andmy appetite was severely depressed. I had lost 40 pounds in about 4 months time.I've noticed a terrific increase in my energy levels and my appetite has returned. I'vegained back about 10 pounds and have starting participating again in the sports thatI missed so much.

I would like to mention that the doctors have told me that about 70% of patients withSarcoidosis go into remission at some point. That may be the case with me, but Ipersonally believe that the CMO played a major part in my recovery. This is the firsttime I have ever felt strongly enough about any product to give a testimonial but Ihave been extremely pleased and thankful for the experience that I had with yourproduct.

Best Regards,Mark Howell (North Carolina)

Nov. 21, 2000Dear Marge,I've procrastinated far too long, so I'm taking this opportunity to tell you what awonderful relief of pain I have had from your products. The CMO products are like amiracle from God. My neck, hips and lower spine have improved 100%. It took onemonth and a half to feel some relief but in another month I am honestly 100%!

My testimonial should encourage those who suffer today from joint pain and swelling,to use these products. They work! I owe these pain free days to CMO.Yours Truly,M. Stephanie Whaley (Surprise, AZ)

Note: Ms. Whaley used CMO capsules in Feb. 2000. Her November testimonial isindicative of the many who report they are still pain free 8 or more months afterusing CMO products.

January 5, 2000Dear Marge,I first ordered CMO Cream for my granddaughter who has an inherited condition onher feet that no doctor has been able to clear up. Within a few days of applying thecream her feet look perfect and don't itch. My two sons who also have the sametrouble (inherited from their father) started using the CMO cream and after just threeapplications saw a marked improvement and kept telling me they can't believe thecondition their feet are in now.Thank you,Pauline M. Harrington paulmlh@aol.com (New Jersey)

Date: Tue, 14 Dec 1999 06:31:56 +0000From: Fredette arkdette@earthlink.netSubject: cmo/sarcoidThis morn I took my last dose of CMO+...my husband asked me the other morning,"How do you feel?" and I said, "Good!" He said he couldn't remember the last time Ihad said that! Last week was my "3-day" teaching week and usually I am a wetnoodle on Thursday from teaching 3 days in a row...but this Thursday I enjoyedputting Christmas decorations up! I still have been trying to take it easy, although mybevery impulse is to dive back into 'normal' life. I have some stiffness in my ankles inthe morning, still, but since that was the first place I ever felt pain, perhaps that willbe the last to go. I have taken 1 motrin over the past ten days...I used to take 3every 4-6 hours! But I could have lived with the pain...the thing that was the hardestfor me was the extreme fatigue that literally took me out of life.I must admit, I am still in a tentative, waiting sort of posture...I just want to see that Ireally am healing, rather than in body-self attack mode.Kathleen Fredette (Palmdale, CA)

Note: Kathleen had a sarcoidosis flare up in May, 2000 and another one in Oct.2000. Both times she took one bottle of CMO+ and then returned to her normalroutine without needing pain medication or other drugs. Kathleen is thirty somethingand the mother of 4 young sons as well as a teacher.

Date: Wed, 22 Sep 1999 12:14:35 -0400From: Viva J. McKinney vmckinne@bellsouth.netDear Marge,I am writing a testimonial about my husband's experience with CMO+. I would very

much appreciate it if you would pass this information along to others that may haveany doubts about its curative powers.In January of this year (1999) my husband was diagnosed with rheumatoid arthritisby three doctors at our nearby clinic. This disease hit him very hard and very fast. Atfirst he was put on Prednisone to ease his pain and swelling while we waited for testresults.In the meantime, I got on the internet to find out more about the disease and whattreatments are available. I was rather alarmed about the facts I was reading on thetoxicity of medications like Prednisone and Methotrexate. Methotrexate wasdescribed as one of the most toxic drugs on the planet. That's when I "happened"across Marge Berger and CMO. I contacted Marge for further information and readthe book giving details of how CMO came into being, along with many testimonials.We went back to the clinic at that time and the "Specialist" wanted to put him onMethotrexate and launched into a diatribe of how safe a drug it is! We left the clinicwith pills in hand, but I'm happy to say he never took them. We decided it would beworth it to take the CMO capsules before contaminating his body with toxic drugs.He was in great pain and had to wear three pairs of socks and wrist braces just tobe able to continue working. He would literally drag himself out of the car andhobble into the house after work and collapse on the bed until the next morning.Because of our finances he was forced to continue working but was only able toendure about 20 hours per week.Then came the miracle of CMO! The four bottles my husband took have brought himback to 90-95% of what he was before he became ill. Now he can work a full daywith no braces or extra socks. Through the four treatments the pain and swellingwould come and go. He had good days and bad days and there were times wewondered if it was really working at all. But he stuck with it and now we are lookingforward to his retirement and freedom from this crippling, life altering disease. Anextra bonus is that his lower back problem of many, many years has also benefitedfrom the CMO. We look forward to a hopeful future in our retiring years.Sincerely,WT and Jean McKinney (Georgia)

Date: Tue, 29 Jun 1999 12:18:02 -0500 (EST)From: grants@mail.zimlink.comDear Marge,It's Mavis Grant from Zimbabwe. Just a little note to share the good news with youabout Beverley Scrooby. She has finished the courses of the CMO and has sincehad blood tests which show that she now has no trace of arthritis!I also wanted to thank you for all your help over the last couple of months!Thanks again.RegardsMavis Grant

From: EEJR1@aol.comSubject: Re: Sarcoid update - July, 1999Dear Marge,Just wanted to email you and let you know that David is still fine. You recall I wroteyou when he recovered from that horrible sarcoidosis in December of last year. Well,it has been seven months now, and he is still at 100 percent fine. We have told somany people about this wonderful product, CMO! Many have tried the product basedon actually SEEING the wonderful recovery from what was a near-death situation! Istill have trouble understanding that he only took the CMO for ten days and on theeleventh day, he felt about 80 percent recovered. Within the next few days, he wasout roller-blading with the kids! I ordered another bottle of CMO for him, but he hasnever needed to take it. So we are keeping it on hand if any of us should ever have

a similar disorder (as insurance!.) Just wanted to give you an update, Marge!Thanks again,Elizabeth Rawlins ( Pensacola, Flordia)

Date: Mon, 10 May 1999 20:20:52 -0400From: Terry Hicks kegler@cybergap.netJust wanted to let you know I have seen an 80 percent improvement since takingyour CMO. My hand and wrist pain is down to a small ache after bowling whereasafter 3 games before I couldn't even pick up a ball the next day. Now I can bowlback to back days and even more if needed. My knees which had cartilage removedand ached during walks have improved also. I really doubted CMO's claims but wasdesperate and it really did work. I tried MSM but seen no improvement with themalone but I did continue taking them with the CMO.Terry Hicks (Pensylvania)

Date: Thu, 11 Mar 1999 12:50:50 +0800From: Alicen Spencer alicenjohn@telstra.easymail.com.auDear Marge,Just a quick note to thank you for sending over the CMO product to us, my fiancéehas appeared to have recovered extremely well and to this date has had no painwhatsoever for the past 2 weeks solid. This result is after having taken the seconddosage of what we ordered from you. We would just like to thank you very much andstate that it is quite like a miracle product.For your information, we have passed on several of your brochures and details andso far 5 other acquaintances of ours have purchase and commenced using CMO.Nothing better than 'word of mouth' promoting. Good luck with an excellent product.Thanks again.Alicen Spencer [ on behalf of John Bosco ] (Australia)

Note: John is a young man whose chronic joint pain and stiffness was secondary toa major auto accident a few years before. 6 months after the message he was stillpain free. Have not heard from him since.

Notice: Not all users have the same results as the authors of thesetestimonials. Human response can vary greatly due to a variety of complex

health and human genetic factors. Those taking immune suppressingmedication, those with liver disease and those with a low thyroid condition

(untreated) usually do not benefit from CMO+ products.

The statements on this web site have not been evaluated by the Food and DrugAdministration. These products are not intended to diagnose, treat, cure, or preventany disease.

who we are | cmo+ facts | testimonials | order

Friday, November22, 2013

My name is Marge Berger.

My company, PermaHEALTH Inc,was originally set up 14 years ago asa company for nutritional consultationsgenerated primarily by MD referrals.However, due to the overwhelmingresponse to our CMO product line, thecompany focus has shifted tomanaging our web generated nutritionmarketing business.

We evolved into an internet company in 1996 after discoveringCMO for our uncle who was an 84 year old widower at the time.He had painful crippled hands and could not take anymedication other than NSAIDs due to his glaucoma. TheNSAIDs no longer worked and his doctor said immunesuppressants were out of the question. He asked me to use mynutrition training to find help for his pain. A tough assignment!

I found CMO on one obscure web site. I was very skeptical. Atthat time (1996) CMO cost $275.00 for 50 capsules. WOW!Uncle Wilbur said any price was not too high if it helped. Threedays after the CMO arrived in his home in PA he called to sayhis hands had not felt this good in 20 years. He told me he wasable to use the wrench that had been sitting on his desk for 2years waiting to fix a loose bolt on his lamp. Every other time hehad tried to squeeze the wrench (even after soaking his handsin hot water) the pain would not allow him to complete thissimple task. He finished 2 bottles of CMO, though after only onebottle he was able to return to all his chores and hobbies thathad been put 'on hold' when NSAIDS no longer worked. He wasable to hang his laundry outside on the line again (he claimeddryers were a luxury that used too much electricity). He optedfor the second bottle for what he said was "insurance". The 2bottles cost him $550 - 3 times what 2 bottles cost today in theyear 2000. He told me 2 years later that it was worth everypenny.

Before we bought the product for our beloved uncle, wechecked the article written by scientist, Dr. Harry Diehl, who wasworking at the National Institutes of Health at the time (early1970's) he discovered the benefits of injectable CMO on thearthritic joints of mice. His article appeared in the Journal ofPharmaceutical Sciences,(VOL 83, #3, March 1994, pages 296-299) and had been written at the insistence of his doctor whowas amazed at the researcher's personal results when he hadinject his own arthritic joints from CMO he extracted in his homelab long after he retired from NHI. Then we called Dr. Sandswho reported that, yes, he and his researchers had indeedcreated the oral analog of CMO from Diehl's research. He saidhe himself had taken the CMO capsules for his knees the year

before and was now no longer dependent on pain medicationand could walk anywhere and even climb stairs.

After seeing Uncle Wilbur's continued joy in living and aftergiving a few more bottles to friends and relatives who hadsimilar results, I decided to market CMO. The results reported bythe early users were generally excellent. This product wasindeed a marvel! Hence our website http://www.bestcmo.comevolved.

I visited Dr. Sands in his clinic in Oct. 2000. He was still mostlyfree from pain, and more importantly ddi not need to constantlytake pain medication (even 6 years after he originally tookCMO). I cannot promise you that our Duoflex CMO+HPR willwork the same way for you because all bodies are complex andrespond differently to products. I can promise you that if you arenot satisfied with your results, I will refund your productpurchase price. To date we have a 10% refund rate. That saysthat 90% of our customers are happy with their results.

We have improved on the original product by adding appropriateproprietary digestive enzymes to aid in better assimilation of theCMO joint formula. We have also combined it with the fantastichomeopathic pain reliever, HPR. Together Duoflex CMO+HPRare helping many arthritics who had resigned themselves to dailypain medication and limited lifestyles. This new combination ofproducts is rapidly becoming the leader in this field.

If you need a refund please wait 30 days after finishing ourproducts to evaluate your overall results.

Why should I wait 30 days?For some customers the response is slow but just as rewarding.Because Duoflex CMO+HPR is not a pain relief drug, thebenefits can be subtle at first. As days go by you may begin tonotice your "quality of life" is back. You smile and realize youare feeling younger, moving faster, walking farther, sleepingbetter, and forgetting to swallow those pain pills. All in all, life isgood again.

Thank you for considering our product and please contact me ifI can be of help as you continue to research to make aninformed decision. Wishing you healthy and happy days ahead.

Marge Berger, NutritionistPermaHealth Inc

P.O. Box 653 Emmaus,PA 18049 USA843.838.4672 - 800.224.8912

email: info@bestcmo.com

The statements on this web site have not been evaluated by the Food and DrugAdministration. These products are not intended to diagnose, treat, cure, or preventany disease.

who we are | cmo+ facts | testimonials | order

SAN DIEGO CLINICTHE FIRST TRIALS

THE SAN DIEGO STUDY:An informal human study was undertaken at a facility called the San Diego Clinic in late 1995. It wasconducted by Dr. Len Sands, Ph.D. It started with some stated objectives:

THE QUESTIONS TO BE ANSWERED WERE:

1. What are the optimum dosage levels for treating the various types of arthritis with CMO?

2. Are different dosages important relative to the different types of arthritis?

3. What is the lag time between the start of the treatment and the expected relief of symptoms?

4. What percentage of patients respond to the treatment?

5. What factors, if any, contribute to non-responsiveness?

The study was conducted with 48 volunteer patients who had (OA) osteoarthritis, (RA) rheumatoid, and (PA)psoriatic arthritis. The group was comprised of 28 females and 20 males ranging from 32 to 82 years of age.All races and all ethnic backgrounds were represented. Age, gender, race and ethnic background appearedto be irrelevant to the results of the program.

CMO was administered orally in the form of 385 mg capsules. The number of capsules and duration oftreatment varied for each group. The final protocol will be found later in this study.

At the end of each trial an evaluation was made using three parameters; inflammation, pain and motion. Allbut four of the subjects in the studies reported 80% to 100% return of articular mobility as well as 70% to100% decrease in pain. Probably the most interesting finding was that the relief of inflammation frequentlyresulted in partial correcting of the deformities. In some cases it resulted in complete corrections. At the endof the entire study, only two subjects said they had failed to notice any change. An examination confirmed nochanges in the pair. These two non-responders had prior hepatic problems, one from alcohol abuseresulting in cirrhosis of the liver and the other had abused steroids for the purpose of bodybuilding. It wasconcluded, then, that liver damage may have been the cause of the failures. This could, at least, be aworking hypothesis for future study. Two other patients showed less than 75% return of articular mobility.

During the entire study and follow-up, there were no discernible side effects.

This was an informal and independent trial at a private medical clinic. It was undertaken by an individualdoctor and other professionals without funding from the government or drug companies. Clinical studies suchas these point out fruitful directions for future studies.

GROUP 1

Eleven (11) subjects, was comprised of mild to moderately severe osteoarthritis, including one case ofreactive psoriatic arthritis. The eleven subjects took two capsules of CMO twice daily for five days and quit.That was the entire treatment.

Nine of the patients reported 20% to 30% improvement in articulation and inflammation and about 40% to50% relief of arthritic pain within 36 hours. Improvements, in the same nine, continued rapidly for the next60 hours, reaching 80% to 100% overall relief by the end of four days. The two remaining subjects reporteda 70% to 80% improvement by the end of the fourth day, and both of them continued to see improvementsover the next week even though they were no longer on the capsules.

Half of this entire group experienced a return of some mild arthritic symptoms after about 3 to 5 weeksfollowing the study. All of them were re

The patient with reactive psoriatic arthritis also experienced an almost complete reversal of his arthritis aswell as his associated severe psoriatic skin condition which affected about 20% of his total skin area.

GROUP 2

Nine patients (9) with severe rheumatoid arthritis were grouped together for a second study. Four patients inthis group required wheelchairs. One of the patients was on crutches because of a hip fusion. Theremaining 4 needed walkers or canes. All of them had pain, inflammation and marked deformations of all thejoints in the fingers as well as restriction of motion. Five had some permanent lower back flexion as well asback pain. All of the patients in this study had difficulty grasping and manipulation common objects.

The dosage schedule was two 385 mg capsules twice a day for 7 days, then stop for 7 days and thenresume for 5 and 1/2 days.

Within three days, six in this group reported a 30% to 50% decrease in pain. Three of the six noticedincreased joint mobility, and another three subjects reported little change. In 7 days, five of the patients hada 70% to 90% decrease in pain and 70% to 80% improvement in joint mobility. Three reported themselvesto be totally free of pain with almost complete return of joint mobility. The joint deformations which werepreviously severe seemed to show marked improvement. Only one failed to show changes.

After they had been off treatment for a week, roughly half said they had seen further improvements, but mostof it was minor. Two of the patients stayed the same. There was no improvement in the individual who hadnot seen improvement from the start. They were then re-treated for another 5 days. By the end of thetreatment period all but two subjects reported themselves to be 90% free of pain, with 70% to 90%improvement in joint mobility. The non

GROUP 3

Group 3 consisted of 14 subjects with severe rheumatoid arthritis. They were given two 385 mg capsules ofCMO twice a day for six days and then nothing. After three days, eleven out of this group had 40% to 50%improvement in articulation and inflammation and 40% to 50% improvement in arthritic pain. All improvedrapidly over the next four days, approaching 80% to 100% level. The remaining three had 70% to 80%improvement after seven days,

Most of the subjects continued to experience minor improvement during the first week off the treatment. Sixpatients, however, noticed some minor recurrence three or four weeks after the treatment and were re-treated in the same manner. Their symptoms disappeared.

GROUP 4

The fourth group organized contained 14 subjects severely crippled with osteoarthritis. They each took two385 mg capsules of CMO twice a day for seven days, then off seven days, then back on for five and a halfdays.

At the onset, three of this group were unable to walk and required wheelchairs. The other eleven usedwalkers, canes or crutches. All of the patients in this group had pain, inflammation and deformationsthroughout their hands and fingers. Four of the patients had severely limited movement of their backs andlower back pain. Ten had difficulty grasping and holding objects.

Four days later, ten of the patients reported a 30% to 50% improvement in movement and lessening ofinflammation. 40% to 50% of their pain was gone. Ten of them continued to see Improvement over the next3 days. In seven days they were 80% to 100% better. One subject showed no change.

On the 14th day, at the end of their week off treatment, 9 had continued to feel improvements. Four stayedthe same and the one who had failed to improve before stayed the same.

They re-started the CMO again for five and a half more days. At the end of the treatment, eleven had 80%to 100% improvement in pain and mobility. Two had 70% to 80% improvement in mobility and 70% to 90%lessening of pain. One patient, the same as before, experienced no relief.

CONCLUSIONS OF THE STUDY

The optimal dosage level appears to be equal for all three types of arthritis:

Osteoarthritis, Rheumatoid and Psoriatic Arthritis. This is evidenced by the gradual return of minor arthriticsymptoms in several of those treated with only 16 to 24 capsules, and no regression in those treated with 50capsules in two series separated by one week without treatment.

Dosage level requirements appear to be equal irrespective of the severity of the subject's condition.

Initial response time for minor improvement appears to vary from two to seven days irrespective of theseverity of the subject's condition.

The time for maximum attainable response appears to be from seven to twenty-one days, resulting in 70%to 100% overall improvement. (Apart from the study three of the most severely afflicted subjects weretreated again after a five week interval resulting in an additional 10% to 20% overall improvement.)

The two non-responding subjects both proved to have suffered previous damage to the liver from steroid oralcohol abuse, indicating that impaired liver function may preclude success with this protocol. In addition, itwas evident that for many subjects the relief of inflammation resulted in marked improvement in jointdeformation.

There were no side effects of the treatment noted by the subjects or the doctors.

Some of the patients were not entirely happy with 70% improvement and so were re-treated 5 weeks later.In general, they benefited another 10% to 20%.

There are, in addition to these studies, hundreds of testimonials and success stories. And the success rate inmost cases, if you count success as being a substantial improvement in symptoms, is an astonishing 98%and all of this without risk to the patient.

This concludes these studies and their results.

SAN DIEGO CLINICMEMORANDUM

Subject: Heart Disease Relative to CMOThere have been no formal studies conducted with respect to the effects of CMO on individuals with heartdisease.

However, considering that CMO is a naturally derived nutritional supplement that has shown to helpnormalize various physiological and immunological body processes in humans, and since it appears to becompletely non

On the contrary, we have received interesting reports regarding persons with certain other ailments whohave taken CMO for arthritis as recommended by their physicians and other health care professionals.

1. There have been reports on individuals suffering from hypertension (high blood pressure) whoseblood pressure has completely normalized or lowered substantially.

2. There have been reports of individuals suffering from hypotension (low blood pressure) whose bloodpressure has completely normalized or raised substantially.

3. There have been reports of individuals with high and even extremely high blood sedi-mentationrates whose sed rates have normalized, even in Lupus patients.

4. There have been reports of individuals with cardiac arrhythmia (abnormal heartbeat rhythm) whosearrhythmia has disappeared.

Those reports are not the result of any formal study. They have been noted from comments provided to usby professionals who have been surprised at these secondary benefits of CMO which they have encounteredin their patients during the treatment for arthritis. This tendency by CMO to normalize body processesconfirms that it functions as an immunomodulator.

It must not be assumed that other patients will enjoy these same secondary benefits. No formal studies havebeen conducted to confirm that these benefits are repeatable on a consistent basis.

It must be emphasized that any individual with a serious ailment or condition of any sort should consult withand be closely monitored by their relevant health care professional any time that person undertakes any sortof therapeutic or even nutritional program.

January 1997

SAN DIEGO CLINICMEMORANDUM

Subject: CMOTM . and HorsesOur very first experience with horses involved a 19-year-old dressage stallion who is considered to be thebest stud horse of that kind on the East Coast. The owners were distressed that the stallion was so severelyafflicted with arthritis that he was unable to move out of his stall, much less participate in dressage practiceor performances. In addition, the horse was not able to rest well because of the arthritic pain. Equallydistressing was the fact that he could no longer perform his breeding duties without resorting to complicatedartificial insemination procedures. We are happy to report that after the administration of four bottles of CMOthe stallion was waking in the morning refreshed and free of pain and able to practice its dressagemaneuvers.

Furthermore tic returned quite comfortably to breeding in the natural way. Needless to say, the owners wereoverjoyed - and we bet the stallion was too.

Another interesting case involved a 14-year-old mare who had become too lame to walk. In all three yearsof working with the horse, her trainer found that she had never been able to canter and sometimes justbarely managed to trot. The mare had very distinct bulging in the tendons her lower front legs. After twobottles of CMO, the horse was no longer lame and the swollen bulges had disappeared. The mare was ableto trot comfortably and even canter again for the first time in years. On a ten point scale estimating painrelief and mobility, the trainer estimated that the horse had improved form a 2.5 level before CMO to a 7.5level after.

More subtle improvements were evident in a case involving another dressage horse that was progressivelybecoming more and more resistant to a right lead. In this instance the trainer had already experienced greatresults with CMO for her own neck and shoulder problems, probably the result of being hauled around anarena by 1000 pound animals for so many years. So why not try CMO on the horse as well? Even beforefinishing the second bottle the horse lost all resistance to the right lead and showed a marked increase influidity of motion which is so important in dressage work.

One horse was conclusively diagnosed as suffering from arthritis by x-ray which clearly revealed thepresence of arthritic bone spurs. After administering three bottles of CMO the owner reports that the bonespurs have decreased in size and are disappearing. We are hoping soon to support the visual evaluationwith X-Ray confirmation as well.

We recently submitted blood samples of a horse undergoing treatment with CMO for the standard analysisrequired on the show horse circuit in California. Nothing unusual appeared in the analysis.

Administering CMO to horses call sometimes be a problem with finicky caters. Some owners use a ball gunwith great success, but some owners prefer to mix the contents of the capsules in with something of whichthe horse is particularly fond. Some find that applesauce works well. Others like grated carrots and apples. Acommercial oat and molasses mixture often works well too. About 20 capsules a day seem to work well foran average size horse.

CMO has been effective an cats, dogs, hamsters, and pot-bellied pigs for arthritis and hip dysplasia as well.Small animals need only one capsule daily. Two capsules daily for each 50 pounds of body weight.

Other Studies:

San Diego Clinic:The First Trials

CMO Testing byMedisure

A RandomizedClinical Trial

The Effects of FishOil on RheumatoidArthritis

What Is PsoriaticArthritis?

CMO Testing by Medisure

Medisure supplied sufficient IMUNALL (brand of CMO) toAdvanced Medical Systems & Design, Ltd. for a two year fieldstudy on the effectiveness of their "natural nutritionalcompound", Cerasomal-cis-9-cetylmyristoleate (CMO), whichhad after earlier research and testing by Medisure, shown to beeffective in relieving the adverse symptoms of arthritis andperhaps other immune system disorders. The main thrust of thisbattery of tests was primarily focused on arthritis.

The study involved 888 female subjects ranging in age from 28to 82, and 926 male subjects ranging in age from 29 - 74. Allraces and many ethnic backgrounds were represented. Age,gender, race, and ethnological background appeared to beirrelevant to patient response in this study. However, youngersubjects seemed to respond earlier to the regimen program.

CMO was administered orally in the form of three capsules eachmorning and evening until the 96 capsules were consumed for16 days. The subjects were examined on the eighth andsixteenth day for evaluation regarding pain, swelling andinflammation.

Encouraging results were found after testing the 1,814 subjects.The results showed that over 87% of the subjects had greaterthan 50% recovery and over 65% of those showed from 75% -100% recovery following a sixteen day regimen. All types ofarthritis were positively affected by CMO.

Studies showed improvement in all subjects except those whohad suffered liver damage or those with digestive problems ordisorders. Otherwise, every patient benefited.

Initial response times for minor improvement varied from two toseven days irrespective of the subject's condition. Approximately95% of the subjects who had favorable response did so withinthe first 10-day period. The other approximately 5% showedfavorable results after a regimen of 16 days and therefore wouldderive the greatest benefit from a full 20-day regimen of twobottles (120 capsules).

It is the opinion of Dr. Ricky Allen,(managing director ofAdvanced Medical Systems and Design, Ltd.), that the newdosage/regimen recommendation be a 60 capsule, 10-dayprogram. This new regimen would give maximum benefit for thegreatest percentage of subjects.

Other Studies:

San Diego Clinic:The First Trials

CMO Testing byMedisure

A RandomizedClinical Trial

The Effects of FishOil on RheumatoidArthritis

What Is PsoriaticArthritis?

Long-Term Fish Oil Supplementation Benefits RA Patients

LEUVEN, BELGIUM. Belgian researchers have released theresults of a major study aimed at determining the long-termeffects of fish oil supplementation in rheumatoid arthritispatients. Sixty patients completed the year-long, double-blind,randomized study. The participants were divided into 3 groupswith 1 group receiving a daily supplement of 6 capsulescontaining 1 gram of olive oil each (placebo); another groupreceiving 3 olive oil capsules plus 3 fish oil capsules (containing1 gram of fish oil each); and the third group receiving 6 fish oilcapsules daily (corresponding to 2.6 grams/day of omega-3 fattyacid). All patients continued on their regular arthritis medications.

Three months into the study it became clear that the patients onfish oil alone had improved considerably when compared to theother 2 groups and this improvement became even morepronounced after 12 months of supplementation. Fifty-three percent of the patients in the fish oil group showed significantoverall (global) improvement as compared to 10% in theplacebo group and 33% in the fish oil plus olive oil group. Forty-seven per cent of the patients in the fish oil group were alsoable to reduce their intake of NSAIDs and disease-modifyinganti-rheumatic drugs as compared to 15% in the placebo groupand 29% in the olive oil plus fish oil group. The researchersconclude that long-term supplementation with fish oils benefitsrheumatoid arthritis patients significantly and may lessen theirneed for NSAIDs and other RA medications.

Geusens, Piet, et al. Long-term effect of omega-3 fatty acidsupplementation in active rheumatoid arthritis. Arthritis &Rheumatism, Vol. 37, June 1994, pp. 824-29

Borage and Fish Oils Go Together

JACKSONVILLE, FLORIDA. Supplementation with gamma-linolenic acid (GLA) found in borage and evening primrose oilsreduces the symptoms of chronic inflammatory diseases such asrheumatoid arthritis and atopic dermatitis. It is believed that thetransformation of GLA to DGLA (dihomo-gamma- linolenic acid)in the inflammatory cells (white blood cells) helps dampen theinflammatory effects of AA (arachidonic acid). Unfortunately,there is a fly in the ointment. While GLA supplementation resultsin a decrease in AA in the inflammatory cells it also causes,somewhat paradoxically, a very significant increase in AA in theblood serum itself. A high blood level of AA is associated withan increased risk of blood clotting and is a potent risk factor forheart disease.

Researchers at the Mayo Clinic now report that the potentiallyharmful effects of GLA supplementation can be eliminated bysimultaneous supplementation with fish oil. Their small clinicaltrial involved a control group of 2 healthy men and 2 healthywomen who consumed a controlled diet while supplementingwith 3 grams/day of GLA (5 capsules of borage oil morning andevening). The active treatment group (5 women and 7 men)followed the same protocol with the addition of 3 grams/day ofEPA (eicosapentaenoic acid) taken in the form of 5 capsules ofconcentrated fish oil (each capsule containing 600 mg of EPAand 280 mg of DHA (docosahexaenoic acid). After 3 weeks ofsupplementation samples of white blood cells and samples ofblood serum were analyzed to determine fatty acid profiles. Bothgroups experienced a marked increase in beneficial DGLA intheir white blood cells. The control group (GLA supplementationonly) also saw a significant increase in detrimental AA in theirblood serum, but no such increase was observed in the grouptaking fish oil as well.

The researchers conclude that the detrimental effects of GLAsupplementation can be avoided by adding fish oils to thesupplementation regimen.

Barham, J. Brooke, et al. Addition of eicosapentaenoic acid togamma-linolenic acid: supplemented diets prevent serumarachidonic acid accumulation in humans. Journal of Nutrition,Vol. 130, 2000, pp. 1925-31

Fish Oils Recommended For RheumatoidArthritis

NEWCASTLE, AUSTRALIA. At least 13 published randomized,controlled clinical trials have reported significant benefits of fishoil supplementation in rheumatoid arthritis patients. Nowresearchers at the University of Newcastle weight in with theadditional evidence to support these earlier findings. Their 15-week study involved 50 patients who had been diagnosed withrheumatoid arthritis. The patients were all consuming a dietwhich contained less than 10 grams/day of omega-6 fatty acids.These fats are known to promote inflammation through theireicosanoid metabolites. Half the patients were given fish oilcapsules to provide a daily intake of 40 mg/kg body weight(about 2.8 grams for a 70 kg person); the other half receivedplacebo capsules containing 50/50 corn/olive oil. All subjectscontinued with their regular diet and medications. About half thepatients dropped out during the experiment, mainly due tochanges in their medications. Complete clinical evaluations werecarried out at baseline, 4, 8 and 15 weeks.

There were no significant changes after 4 or 8 weeks, but at the15-week evaluation major improvements were noted in thegroup receiving fish oil. Particularly impressive were theimprovements in the duration of morning stiffness and theoverall assessment of disease activity (by both patients andphysicians). Significant improvements were noted in 6 of the 9evaluation parameters in the fish oil group; no improvementswere noted in the control group. Only the total number of jointsaffected, the erythrocyte sedimentation rate (ESR), and the C-reactive protein level were unaffected by supplementation.

In an accompanying editorial Drs. Cleland and James of theRoyal Adelaide Hospital emphasize the importance ofmaintaining a low intake of omega-6 fatty acids in order to keepthe ratio of omega-6 to omega-3 as low as possible. Theyconclude that "dietary fish oil supplements should now beregarded as part of standard therapy for rheumatoid arthritis".

Volker, Dianne, et al. Efficacy of fish oil concentrate in thetreatment of rheumatoid arthritis. Journal of Rheumatology, Vol.27, October 2000, pp. 2343-46

Cleland, Leslie G. and James, Michael J. Fish oil andrheumatoid arthritis: antiinflammatory and collateral healthbenefits. Journal of Rheumatology, Vol. 27, October 2000, pp.2305-06 (editorial)