Institute for Public Health GeneticsInstitute for Public Health GeneticsA University Initiatives Fund Program

Institute for Public Health GeneticsInstitute for Public Health GeneticsA University Initiatives Fund Program

Soul Catcher: Northwest Coast Indian symbol of physical and mental well being.Artist: Marvin Oliver

http://depts.washington.edu/phgenhttp://depts.washington.edu/phgen

What is Public Health Genetics?What is Public Health Genetics?What is Public Health Genetics?What is Public Health Genetics?The application of advances in human

genetics and genomic sciences to improve public health and prevent disease.

UW Institute for Public Health GeneticsUW Institute for Public Health GeneticsMission: To provide broad,

multidisciplinary training for future public health professionals, to facilitate

research in public health genetics, and to serve as a resource for continuing

professional education.

Core Faculty in Public Health GeneticsCore Faculty in Public Health Genetics

Dept of Medical Dept of Medical History and Ethics History and Ethics (Medicine)(Medicine)

Epidemiology, Epidemiology, Biostatistics,Biostatistics,

Environ & OccupEnviron & OccupHealth Sciences, Health Sciences, Health Services,Health Services,

PathobiologyPathobiology

School of LawSchool of Law

Fred Hutchinson Fred Hutchinson Cancer Research Cancer Research

CenterCenter

School of School of PharmacyPharmacySchool of School of

NursingNursing

Dept of Dept of AnthropologyAnthropology(Arts & Sciences)(Arts & Sciences)

Evans Evans School School of Public of Public AffairsAffairs

Washington Washington State Dept State Dept of Healthof Health

Public Health SciencesPublic Health Sciences

Institute for Public Health Genetics Institute for Public Health Genetics Multidisciplinary Academic ProgramMultidisciplinary Academic ProgramInstitute for Public Health Genetics Institute for Public Health Genetics Multidisciplinary Academic ProgramMultidisciplinary Academic Program

Master of Public Health (MPH) Degree Track (1998)

Graduate Certificate Program (1998)M.S. Degree Track in Genetic

Epidemiology (2003)Ph.D. program in Public Health

Genetics (2003)

Public Health Genetics CompetenciesAustin et. al., Community Genetics, 2001

Public Health Genetics CompetenciesAustin et. al., Community Genetics, 2001

1. Apply knowledge of inheritance, including basic cellular and molecular mechanisms, to understand a variety of rare and common health conditions.

2. Apply epidemiological and statistical approaches to the study of risk factors and diseases with a genetic component.

3. Identify interactions among genes, environmental factors and behaviors.

Public Health Genetics Competencies (con’t)Public Health Genetics Competencies (con’t)

4. Understand how genetic principles/technologies apply to diagnosis, screening, and interventions for disease prevention and health promotion programs.

5. Incorporate genetic information into assessment, policy development, and assurance activities.

6. Apply methods to address ethical, legal, social and financial implications of the use of genetic principles/technologies in public health, including protecting privacy and autonomy, and preventing discrimination.

Ethics & Social

Science

Public Health

Human Genetics

Ecogenetics & Pharmaco-

genetics

Genetic Epidemiology

Health Economics &

Outcomes Research

Law & Policy

Training in Public Health Genetics

FundamenFundamental Areas tal Areas of Studyof Study

Core Knowledge Core Knowledge AreasAreas

A. Genomics in Public Health

B. Implications of Genetics for

Society

Public Health Genetics CoursesPublic Health Genetics CoursesPublic Health Genetics CoursesPublic Health Genetics CoursesMPH Core CoursesMPH Core Courses

• Genetic Epidemiology• Basic Concepts in

Pharmacogenetics and Toxicogenomics

• Legal, Ethical and Social Issues in Public Health Genetics

• Socio-Cultural Perspectives on Public Health Genetics

• Ethical Frameworks of Public Health Genetics

• Genetics and the Law

Ph.D. coursesPh.D. courses• Economic and Policy

Issues for Genetic Technologies and Services

• Genetic Discovery in Medicine and Public Health

• Social and Behavioral Research Methods in Public Health Genetics

Electives Electives Interactive Seminar SeriesInteractive Seminar Series

UW Institute for UW Institute for Public Health Genetics Public Health Genetics

CollaborationsCollaborations

CDC-funded UW Center for Genomics and Public Health

Ethical, Legal and Social Implications Core of the UW Center for Ecogenetics and Environmental Health

A vision of the future of genomics research:

A blueprint for the genomic era

Collins, Green,Guttmacher,Guyer, on behalf of NHGRI

Nature 422: 835-847 (April),2003

Themes (floors), cross-cutting elements,“Grand Challenges”