+ All Categories
Home > Documents > DRUG STUDY

DRUG STUDY

Date post: 30-Oct-2014
Category:
Upload: joy-jarin
View: 204 times
Download: 3 times
Share this document with a friend
Description:
Ferrous Sulfate, Magnesium Sulfate, Oxytocin, etc.
Popular Tags:
14
Generic Name / Brand Name Classification Stocks Indication ( client Specific) Dosage & Frequency Mechanism of action Side Effect / Adverse Reaction Nursing Responsibilities Includes Health Teaching and implication (Pre, Intra, Post) FeSO 4 (Ferrous sulfate) - For Iron Preparation Classification: Hematologic Drug Anti-anemic Iron deficiency and prophylaxis for iron deficiency anemia Pregnant patient 150 mg PO daily during last 2 trimesters Elevates the serum iron concentration which then helps to form High or trapped in the reticuloendo- thelial cells for storage and eventual conversion to a usable form of iron. - temporary staining of the teeth - constipation - black or dark- colored stools - upset stomach - anorexia Advice patient to take medicine as prescribed. Caution patient to make position changes slowly to minimize orthostatic hypotension. Instruct patient to avoid concurrent use of alcohol or OTC medicine without consulting the physician. Advice patient to consult physician if irregular heartbeat, dyspnea, swelling of hands and feet and hypotension occurs. Inform patient that angina attacks may occur 30 min. after administration due reflex tachycardia. Encourage patient to comply with additional intervention for
Transcript
Page 1: DRUG STUDY

Generic Name / Brand Name

Classification Stocks

Indication( client

Specific) Dosage & Frequency

Mechanism of action

Side Effect / Adverse Reaction

Nursing Responsibilities Includes Health Teaching and implication

(Pre, Intra, Post)

FeSO4

(Ferrous sulfate)- For Iron Preparation

Classification:Hematologic DrugAnti-anemic

Iron deficiency and prophylaxis for iron deficiency anemia Pregnant patient 150 mg PO daily during last 2 trimesters

Elevates the serum iron concentration which then helps to form High or trapped in the reticuloendo-thelial cells for storage and eventual conversion to a usable form of iron.

- temporary staining of the teeth- constipation- black or dark-colored stools- upset stomach- anorexia

Advice patient to take medicine as prescribed.

Caution patient to make position changes slowly to minimize orthostatic hypotension.

Instruct patient to avoid concurrent use of alcohol or OTC medicine without consulting the physician.

Advice patient to consult physician if irregular heartbeat, dyspnea, swelling of hands and feet and hypotension occurs.

Inform patient that angina attacks may occur 30 min. after administration due reflex tachycardia.

Encourage patient to comply with additional intervention for hypertension like proper diet, regular exercise, and lifestyle changes and stress management.

Page 2: DRUG STUDY

Generic Name / Brand NameClassification

Stocks

Indication( client

Specific) Dosage & Frequency

Mechanism of action Side Effect / Adverse Reaction

Nursing Responsibilities Includes Health Teaching and implication

(Pre, Intra, Post)

GN: AmpicillinBN: Pricipen

Pharmacologic Class: Penicillin

Therapeutic Class:Antibiotic

Route/ Dosage:Cesarean Section Prophylaxis:

IV Single dose immediately after cord clamping. ( 2 grams )

Indication:

Prophylaxis in cesarean section in certain high risk patients.

Inhibits bacterial cell wall mucopeptide synthesis.

CNS:Dizziness; fatigue; insomnia; reversible hyperactivity; neurotoxicity ( lethargy, neuromuscular irritability, hallucinations, convulsions, seizures)GI:Diarrhea; pseudomembranous colitisGU:Interstitial nephritis (eg, oliguria, hematuria, pyuria); nephropathy; vaginitis; increase in creatinineHEMA:Decrease Hct, Hgb, RBC, WBC, neutrophils, lymphocytes, platelets; increase monocytes, basophils, eosinophils and platelets.DERM:Urticaria, maculopapular to exfoliative dermatitis; vesicular eruptions; skin rashesMETA:Elevated serum alkaline phosphatase, glutamic oxaloacetic transminase; reduced serum albumin and total proteinsOther:Pain at injection site; hyperthermia

PRE:- Obtain patient history, including drug history

and known allergies.- Review results of culture and sensitivity

testing, as available.INTRA:- Monitor patient’s condition closely for

several hours after administering the first dose even when there is no history of allergy.

- Notify the physician of any signs or symptoms of hypersensitivity or anaphylactic reaction.

- Evaluate the skin daily for presence of classic ampicillin rash, usually macupapular, and pruritic and generalized.

- Monitor for bleeding in patients receiving anticoagulant therapy.

POST:- Inform the patient to notify the physician

immediately if rash develops or if patient has difficulty of breathing.

- Tell the patient to increase fluid intake to 2000 – 3000 ml/day, unless contradicted.

Page 3: DRUG STUDY
Page 4: DRUG STUDY

Generic Name / Brand NameClassification

Stocks

Indication( client Specific) Dosage

& FrequencyMechanism of action Side Effect /

Adverse Reaction

Nursing Responsibilities Includes Health Teaching and implication

(Pre, Intra, Post)

Magnesium sulfate

CNS depressant

Seizures of eclampsia (toxemia of pregnancy)

Anticonvulsant:♥IM = loading dose (10 g of 50% solution [20 mL] divided into 2 doses); maintenance dose (4 – 5 g of 50% solution [10 mL] q4H deep IM; alternate buttocks♥ IV = loading does (4 g MgSO4 in 250 mL of D5W infuse at 10 mL per minute; maintenance dose (1 – 2 g per hour by continuous infusion)

♥ CNS depressants = potentiate CNS depressant effects of MgSO4 (barbiturates, analgesics, general anesthetics, tranquilizers, and alcohol♥ Neuromuscular blocking agents = concurrent use with MgSO4 will further depress muscular activity.

♥ Deep tendon reflexes = absent♥ Decreased urine output♥ Decreases respiratory rate, blood pressure, fetal heart rate (fetal distress)♥ Confusion♥ Neonates = hypotension, hyporeflexia, respiratory depression

Pregnancy safety: Magnesium sulfate is administered to treat toxemia of pregnancy. It is recommended that the drug not be administered in the 2 hours before delivery, if possible. IV calcium gluconate or calcium chloride should be available as an antagonist to magnesium if needed. Convulsions may occur up to 48 hr after delivery, necessitating continued therapy. The "cure" for toxemia is delivery of the baby. Magnesium must be used with caution in patients with renal failure, since it is cleared by the kidneys and can reach toxic levels easily in those patients. Prophylactic administration of magnesium sulfate for patients with acute myocardial infarction should be considered.

GN: OxytocinBN: Syntocinon

Pharmacologic Class: Posterior pituitary hormoneTherapeutic Class: Uterine-active agent

To induce or stimulate labor

10 units/ml in1ml ampule, vial or syringe incompatible IV solution.

As for endogenous oxytocin, but with little vasopressin activity

Stimulates uterine contraction

Stimulates lactating breast to eject milk

HypertensionCardiac outputNauseaVomitingAsphyxiaLow APGAR score

Continuously monitor contraction, fetal and maternal heart rate, and blood pressureMonitor patient extremely closely during 1st and 2nd labor because of risk of cervical laceration and uterine rupture and maternal and fetal death.

Page 5: DRUG STUDY
Page 6: DRUG STUDY

Generic Name / Brand NameClassification

Stocks

Indication( client Specific)

Dosage & Frequency

Mechanism of action

Side Effect / Adverse Reaction

Nursing Responsibilities Includes Health Teaching and implication

(Pre, Intra, Post)

GN: HydralazineBN: Apresoline

Cardiovascular System Drug

Pre-eclampsia /eclampsia

5 mg/dose then 5-10 mg every 20-30 minutes as needed. (TIV)

Hydralazine↓

Directly relaxes arteriolar smooth

muscle↓

Vasodilaion↓

Lowers Blood Pressure

♥ CNS: headache, dizziness♥ CV: orthostatic hypotension, tachycardia, arrythmias, angina, palpitations.♥ GI: n/v, diarrhea, anorexia♥ Metabolic: weight gain, sodium retentionSkin: rash

♥ Assess blood pressure before starting therapy and regularly thereafter.♥ Instruct client to take oral form with meals.♥ Inform client that orthostatic hypotension can be minimized by rising slowly and not changing position suddenly.♥ Tell pt. not to abruptly stop taking drug, but to call the one who prescribed it if adverse reaction occurs.♥ Tell client to limit sodium intake.

GN: CefuroximeBN: Ceftin, Zinazef

Anti-Infective

Bacterial infections, such as:

♥ bronchitis♥ gonorrhea♥ Lyme disease♥ infections of the ears, throat, sinuses, urinary tract, and skin750 mg cefuroxime sodium I.V q 8 hours for 5 days.

Second-generation pephalosporin that inhibits cell-wall synthesis, promoting osmotic instability; usually bactericidal.

♥ nausea♥ anorexia♥ vomiting♥ diarrhea

♥ Determine history of hypersensitivity reactions to cephalosporin, penicillin, and history of allergies, particularly to drugs, before therapy is initiated.♥ Inspect IM and IV injection sites frequently for signs of phlebitis.♥ Report onset of loose stools or diarrhea. Although pseudo membranous colitis.♥ Monitor I&O rates and pattern: Especially important in severely ill patients receiving high doses. Report any significant changes.♥ Prior to reconstitution, protect drug from light. The power and reconstituted drug may darken without affecting potency.

Page 7: DRUG STUDY
Page 8: DRUG STUDY

Generic Name / Brand NameClassification

Stocks

Indication( client Specific)

Dosage & Frequency

Mechanism of action Side Effect / Adverse Reaction

Nursing Responsibilities Includes Health Teaching and implication

(Pre, Intra, Post)

GN: PhenerganBN: Promethazine HCI

anti-emetics, antihistamines, sedative/hypnotics

Preoperative sedation, treatment and prevention of nausea and vomiting, adjunct to anesthesia and analgesia.

25-50 mg (sedation); 10-25mg q 4hr as needed (anti-emetic) (1amp)

Selectively blocks H1 receptors, diminishing the effects of histamine on cells of the upper respiratory tract and eyes and decreasing the sneezing, mucus production, itching and tearing that accompany allergic reactions. blocks cholinergic receptors in the vomiting center that are believed to mediate the nausea and vomitting caused by gastric irritation.

CNS: neuroleptic malignant syndrome, confusion, disorientation, sedation, dizziness, extrapyramidal reaction, fatigue, insomnia, nervousness;

EENT: blurred vision, diplopia, tinnitus;

CV: bradycardia, hypertension, hypotension, tachycardia;

GI: constipation, drug-induced hepatitis, dry mouth; Derm: photosensitivity, rashes;

Hema: blood dyscrasias

Monitor BP, pulse and respiratory rate frequently.

Assess level of sedation after administration.

Assess patient for nausea and vomiting before and after administration.

Administer each 25mg slowly over at least 1 hr.

Do not give rectal supp or tabs to children younger than 2 years old because of risk of fetal respiratory depressions

Give IM injections deep into muscle Do not administer SQ, tissue necrosis

may occur Arteriospasms and gangrene of artery

may occur when administered intra-arterially.

Reduce dosage of barbiturates given concurrently within promethazine by least half.

Page 9: DRUG STUDY

Generic Name / Brand NameClassification

Stocks

Indication( client Specific)

Dosage & Frequency

Mechanism of action Side Effect / Adverse Reaction

Nursing Responsibilities Includes Health Teaching

and implication(Pre, Intra, Post)

GN: BuscopanBN: Hyoscine Butylbromide

Anti-emetic

To reduce secretions perioperatively.

Given via IV, 1mg/ml to promote cervical effacement.

Hyoscine Butylbromide↓

Inhibits muscarinic actions of acetylcholine in the ANS

↓Affecting neural pathway

↓Relieves spasticity, nausea and

vomitting; reduces secretions; and blocks cardiac vagal reflexes.

↓Promotes cervical effacement

CNS: dizziness, headache, restlessness, disorientation, irritability, fever

GI: constipation, dry mouth, nausea, vomiting

CV: palpitations, tachycardia, flushing

EENT: dilated pupils, blurred vision, photophobia, dysphagia

GU: urinary hesitancy, urinary retention

Skin: rash, dryness

Be alert for adverse reactions and drug interactions.

Encourage pt. to void Monitor BP for possible

hypotension. Monitor cervical

effacement and dilatation.

D5LR

Class: Hypertonic- Non-pyrogenic, parenteral fluid, electrolyte and nutrient plenisher

- Treatment for persons needing extra calories who cannot tolerate fluid overload.Dosage: 20 drops/ minute

Hypertonic Solutions are those that have an effective osmolality greater than the body fluids. This pulls the fluid into the vascular by osmosis resulting in an increase vascular volume. It raises intravascular osmotic pressure and provides fluid, electrolytes and calories for energy

-Increased serum osmolality-Hypernatremia-Hypokalemia-Altered thermoregulation

- Check vital signs frequently. Report adverse reactions.

Page 10: DRUG STUDY

Generic Name / Brand Name

Classification Stocks

Indication( client Specific)

Dosage & Frequency

Mechanism of action Side Effect / Adverse Reaction

Nursing Responsibilities Includes Health Teaching and

implication(Pre, Intra, Post)

GN: NubainBN: Nalbuphine Hydrochloride

Narcotic agonist-antagonist analgesic

Relief of moderate to severe pain

♥ Preoperative analgesia, as a supplement to surgical anesthesia, and for obstetric analgesia during labor and delivery

Injection – 10 mg/ml, 20mg/ml

Nalbuphine acts as an agonist at specific opioid receptors in the CNS to produce analgesia,sedation but also acts to cause hallucinations and is an antagonist at µ receptors

CNS: Sedation, clamminess, sweating, headache,nervousness, restlessness,depression crying, confusion, faintness, hostility, unusual dreams, hallucinations, euphoria, dysphoria, unreality, dizziness, vertigo,floating feeling, feeling of heaviness, numbness, tingling, flushing, warmth, blurred vision.

CV: Hypotension, Hypertension, bradycardia, tachycardia

DERMATOLOGIC: Itching, burning, urticaria

GI: Nausea,vomiting, cramps,dyspepsia, bitter taste, dry mouth

GU: Urinary urgency RESPIRATORY: Respiratory

depression, dyspnea, asthma

Monitor respiratory rate before and after giving nubain because it causes respiratorydepression

Monitor I and O todetermine if there isexcessive fluid loss

Monitor Bp before andafter administeringthe medication to prevent any complication


Recommended