Chemical Name/Generic Name

Brand Name

Functional Class Dose, Route, Frequency

Action Indication Contraindication

Side Effects

Nurses Responsibilities

Nurokind

Nervijen750mcg,

Nootropics & Neurotonics/Neurotrophics / Vitamin B-Complex / with C

Oral, sublingual, injection.

NUROKIND PLUS cap: methylcobalamin 1.5 mg, folic acid 1.5 mg, vitamin B1 10 mg, vitamin B6 3 mg, alpha lipoic acid 100 mg.Click

VitB12 deficiency,Peripheral neuropathy,

Hypersensitivity.

Assess for hypersensitivity reactions.

Cortiza

Ecospirin

Aspirin BP 75 mg.

Antiplatelet (inhibitor of platelet aggregation)

Thrombot ic cerebrovascular orcardiovascular disease: 4 tablets ofECOSPRIN 75 daily.After myocardial infarction: 2 tablets ofECOSPRIN 75 daily for one month.Following bypass surgery: One tabletof ECOSPRIN 75 daily

Itinhibits the formation of cyclooxygenaseproducts (Thromboxanes,Prostaglandins, Prostacycl ins) .

Prophylaxis against arterial occlusiveevents : Stroke, myocardial infarction,myocardial reinfarction and afterbypass surgery.

hypersensi tive and gastrointestinal ulceration, last 3 months ofpregnancy.

nausea, dyspepsia,gastrointestinal ulceration, bronchospasmand asthma in hypersensitivepatients

It should be administeredwith caution to patients in asthma,nasal polyps, and allergy. Aspirinpenetrates into breast milk, so itshould

be administered with caution tolactating mother.

Clodrel Clopact 75mg,Clopiget 75mg,). Aclotil

antiplatelet agent (thienopyridine class),

Anticoagulants, & Fibrinolytics (Thrombolytics)

Oral Prophylaxis of thromboembolic disordersAdult: 75 mg once daily.Acute coronary syndrome Adult: For ST-elevation myocardial infarction: In combination with aspirin: 75 mg once daily. Patients ≤75 years old may be given a loading dose of 300 mg. Continue treatment for up to 28 days. For unstable angina, non-ST-elevation myocardial infarction: Initial: 300 mg loading dose, followed by 75 mg once daily (with aspirin 75-325 mg once daily

inhibits the binding of adenosine diphosphate to its platelet receptor and the subsequent ADP-mediated activation of the glycoprotein GPIIb/IIIa complex, thereby inhibiting platelet aggregation.

Given alone or with other medications for prevention or treatment of stroke and heart attack (which are usually caused by blood clots)

Lactation, hypersensitivity, peptic ulcer or bleeding within the skull

Dyspepsia, abdominal pain, nausea, vomiting, flatulence, constipation, gastritis, gastric and duodenal ulcers. GI upset, diarrhoea, paraesthesia, vertigo, headache, dizziness, pruritus and rashes. Bleeding disorders including GI and intracranial haemorrhage. Blood dyscrasias

Co-admin with NSAIDs may increase the risk of stomach and intestinal bleeding. High-dose clopidogrel may lead to increased warfarin levels thus increasing the risk of

bleeding.

Caution needed for patients at risk of increased

bleeding from trauma, surgery, or other pathological conditions; ulcer; liver and kidney impairment; history of bleeding or haemostatic disorders, pregnancy.*Avoid injury or bruising while taking this medication.*It may

cause dizziness, avoid driving a car or operating machinery, or other unsafe tasks.

Megteol

Dobutamine

Cardiforce Inj, Dobutam , Dobutasys Inj, Dobutrex Vial, Dobutrop Inj, Dotamin Vial,

beta-adrenergic stimulating agent, Ionotropic agent.

Dilute with dextrose 5% in water or normal saline solution to at least 50 ml of solution. Know that drug is incompatible with alkaline solutions, such as sodium bicarbonate injection.

Stimulates beta1-adrenergic receptors of heart, causing a positive inotropic effect that increases myocardial contractility and stroke volume. Also

severe chronic congestive heart failure and to provide adjunct in cardiac surgery.

Idiopathic hypertrophic subaortic stenosis or known hypersensitivity

cardiovascular effects, including tachycardia, hypertension, arrhythmias, and precipitation of angina. Nausea, vomiting, and

Monitor ECG and blood pressure continuously during administration.• Monitor fluid intake and output.

Icidob Vial, Inoject Inj, Kardia Amp.

Route

Onset

Peak

Duration

I.V.1-2 min

10 min

Brief

reduces peripheral vascular resistance, decreases ventricular filling pressure, and promotes atrioventricular conduction

headache may also occur.

.Assess electrolyte levels. Stay especially alert for hypokalemia.

• Instruct patient to report anginal pain, headache, leg cramps, and shortness of breath.• Explain need for close observation and monitoring.• As appropriate, review all other significant and life-threatening adverse reactions

and interactions,

Doxidin

Folipar Folate, Folic acid

VitB Complex group. 400mcg, subcutaneous/iv .8-1mg/day.

Needed for erythropoesis, increases RBC,WBC,platelet formation in megaloblastic anemia.

Megaloblastic or macrocytic anemia caused by folic acid deficiency, hepatic disease, alcoholism, hemolysis, intestinal obstruction.

Hypersensitivity, anemias other than megaloblasstic/ macrocytic anemia, Vit B12 deficiency,, uncorrected perinicious anemia.

Flushing, Bronchospasm

Assess for fat igue, dyspnoea, weakness.

Insulin

Ismo(isosorbide mononitrate)

Imdur®, Ismo®, Monoket®.

Nitrate 20 mg (one tablet) twice daily, with the two doses given 7 hours apart

its nitric oxide metabolite, is direct relaxation of vascular smooth muscle. The result is dilatation of

angina pectoris due to coronary artery disease.

Hypersensitivity. arrhythmias

, atrial

fibrillation,

hypotensio

n,

palpitation

careful clinical or hemo-dynamic monitoring must be used to avoid the hazards

peripheral arteries and veins.

s, postural

hypotensio

n,

premature

ventricular

contraction

s,

supraventri

cular

tachycardi

a, syncope.

pruritus,

ras

h.abdomina

l pain,

diarrhea,

dyspepsia,

tenesmus,

tooth

disorder,

vomiting.

dysuria,

impotence,

of hypotension and tachycardia.

urinary

frequency

.asthenia,

blurred

vision, cold

sweat,

diplopia,

edema,

malaise,

neck

stiffness,

rigors.

arthralgi

a.agitation,

anxiey,

confusion,

dyscoordin

ation,

hypoesthesi

a,

hypokinesia

, increased

appetite,

insomnia,

nervousnes

s,

nightmares

.bronchitis,

pneumonia,

upper-

respiratory

tract

infection

Vit K Phylloquinone; K1; Menaquinone; K2; sMenadione; K3

Nutrients

List

No.

Container

Inj. In

Container

Volume

Concentration

9157

1 mL Ampul

1 mg 0.5 mL

2 mg/mL

9158

1 mL Ampul

10 mg

1 mL

10 mg/mL

Oral-Whenever possible, Vitamin K1 Injection (Phytonadione Injectable Emulsion, USP) should be given by the subcutaneous route. When intravenous administration is considered unavoidable, the

Promotes hepatic formation of active prothrombin(Factor II), proconvertin(factorVII), Plasma thromboplastin component or Christmas

Hypoprothrombinemia (prophylaxis and treatment), hemorrhagic disease of the newborn.

Hepatic function impairment, Glucose-6-phosphate dehydrogenase (G6PD) deficiency.

Flushing, redness, pain or swelling at place of injection, unusual taste.

Assess for bleeding: emesis, stools, urine.PT during treatment , monitor for bleeding,pulse

drug should be injected very slowly, not exceeding 1 mg per minute.

factor(factor IX),stuart factor (factorX), which are essential for normal blood clotting.

and BP.Nutritional status: liver, spinach, coffee, asparagus, cabbage, lettuce, greens.