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DysphagiaDr. Ali M Ahmad
Consultant Pediatric Surgery; MBBCH, MS, MD, MRCS-ED, EBPS
Associate Pediatric Surgery KAAUH_ PNU
Dysphagia
Difficulty in swallowing
Sensation of food being hindered in its normal passage from the mouth to the stomach
Dysphagia
1. May be underlying Serious disease
2. Its complications: Risk of aspiration pneumonia Malnutrition, dehydration, weight loss Others
Can be a serious health Problems
Applied Anatomy
Anatomy of the esophagus
25 cm Soft muscular tube From the lower border of the cricoid (C6) Descends posterior mediastinum {Front of
the spine} Passes through Diaphragm into the
abdomen Terminates at the cardiac orifice of the
stomach, opposite to T11 vertebra
3 Natural constrictions
Site LevelCricopharynx C 6Aortic arch T 4Oesophageal hiatus T 10
Upper Esophageal sphincters {UES}
True sphincter {striated muscle} Level C5-C6 level Fibers of cricopharyngeus, part of the
inferior constrictor, which encircles the oesophageal entrance
Lower Esophageal sphincters
Physiological sphincter
High-pressure zone located where the
esophagus merges with the stomach
Swallowing phases
Oro-Pharyngeal stage Mastication Salivation Tongue/ soft palate movements Closure of oral/ nasopharynx/ larynx Opening of cricopharynx
Esophageal stage Involuntary propulsion of bolus
Causes of Dysphagia
Oral Causes of dysphagia
Congenital Cleft palate
Inflammatory Stomatitis, ulcer, TMJ arthritis ……….etc.
Trauma Maxilla/ mandible, cheek/ tongue bite, corrosive poisoning
Neurological Palsy: palatal/ lingual/ facial Spasm: trismus/ tetanus
Neoplastic Salivary tumors, carcinoma, jaw tumors ……… etc.
Oral Causes of dysphagia
Congenital Cleft palate
Oral Causes of dysphagia
Inflammatory Stomatitis, ulcer, TMJ arthritis ……….etc.
Oral Causes of dysphagia
Trauma Maxilla/ mandible, cheek/ tongue bite, corrosive
Oral Causes of dysphagia
Neurological Palsy: palatal/ lingual/ facial Spasm: trismus/ tetanus
Oral Causes of dysphagia
Neoplastic Salivary tumors, carcinoma, jaw tumors ……… etc.
Pharyngeal Causes of dysphagia
Congenital Pharyngeal diverticulum (Zenker’s diverticulum)
Inflammatory Pharyngitis, retro-pharyngeal abscess, acute epiglottitis, etc.
Trauma FB, corrosive poisoning, iatrogenic trauma, road traffic accidents
Neurological Cricopharyngeal spasm, VC palsy (aspiration), tetanus, etc.
Neoplastic Benign: salivary tumors, papilloma, etc., Malignant: tongue/ hypopharynx/ larynx, salivary tumors, etc.
Pharyngeal Causes of dysphagia
Congenital Pharyngeal diverticulum (Zenker’s diverticulum)
Pulsion diverticulum Originates in the midline of the
posterior wall of the hypopharynx at an anatomic weak point known
as Killian's dehiscence Above cricopharyngeus at fiber
divergence with inferior pharyngeal constrictor
During swallowing increased
intraluminal pressure forces
mucosa to herniate through the wall
Pharyngeal Causes of dysphagia
Congenital Pharyngeal diverticulum (Zenker’s diverticulum)
Pharyngeal Causes of dysphagia
Inflammatory Pharyngitis, retro-pharyngeal abscess, acute epiglottitis, etc.
Pharyngeal Causes of dysphagia
Trauma Corrosive poisoning, iatrogenic trauma, road traffic accidents
Pharyngeal Causes of dysphagia
Neurological Cricopharyngeus spasm, VC palsy (aspiration), tetanus, etc.
Pharyngeal Causes of dysphagia
Neoplastic Benign: salivary tumors, papilloma, etc., Malignant: tongue/ hypopharynx/ larynx, salivary tumors, etc.
Esophageal Causes of dysphagia
Congenital Congenital esophageal stenosis, Vascular Ring {Double Aortic Arch}
Inflammatory GERD esophagitis, strictures
Trauma FB, Corrosive esophageal stricture
Neurological Achalasia, Scleroderma, Diffuse esophageal spasm
Neoplastic Benign: Leiomyoma Malignant: Esophageal cancer
Esophageal Causes of dysphagia
Congenital Congenital esophageal stenosis, Double Aortic Arch
Esophageal Causes of dysphagia
Congenital Congenital esophageal stenosis, Vascular Ring {Double Aortic Arch}
Esophageal Causes of dysphagia
Inflammatory GERD esophagitis, strictures
Common cause of esophagitis Common in adults over age 40 Common symptoms is
heartburn Esophageal stricture is
common complication
Esophageal Causes of dysphagia
Trauma FB, Corrosive esophageal stricture
Coins is most common in children Meat bolus is most common in adults Foreign bodies in adults may be due to an
underlying stricture that should be ruled out after foreign body removal
Endoscopic Removal
Esophageal Causes of dysphagia
Trauma FB, Corrosive esophageal stricture
Esophageal Causes of dysphagiaNeurological
Achalasia Scleroderma Diffuse
esophageal spasm
Failure of relaxation of LES
Degeneration of myenteric plexus
Long standing dysphagia and regurgitation
Barium swallow: dilated esophagus with a smooth tapering stricture at its lower end
Esophageal Causes of dysphagiaNeurological
Achalasia Scleroderma Diffuse
esophageal spasm
Generalized disorder of connective tissue affecting skin and many other organs.
Dysmotility of gut Normal peristalsis in the proximal
striated esophagusAbsent peristalsis in the distal
smooth muscle portion
Esophageal Causes of dysphagia
Neurological
Achalasia Scleroderma Diffuse
esophageal spasm
Dysphagia, Intermittent abdominal pain & constipation Fingers swollen , stiff and tips become ulcerated. Trismus, Raynaud phenomenon, Polyarthritis…… etc.
Barium swallow shows dilated esophagus and loss of peristalsis in distal esophagus, patulous LES.
Skin biopsy confirms diagnosis
Treatment: Proton pump inhibitors & Metoclopramide
Esophageal Causes of dysphagia
Neurological
Achalasia Scleroderma Diffuse
esophageal spasm
Primarily involvement of lower 1/3 High pressure nonperistaltic contractions Severe chest pain / dysphagia Treatment:
Calcium channel blockers Balloon dilatation Botox Heller myotomy
Esophageal Causes of dysphagia
Neoplastic Benign: Leiomyoma Malignant: Esophageal cancer
Ten fold rise in the last 20 y
This increase is not squamous cell carcinoma but in the incidence of adenocarcinoma
Related to damaging effects of GERD
Approach to Diagnosis
History Exam
Investigations
Children: Foreign body or congenital malformation
Middle aged: Reflux oesophagitis, achalasia
Elderly: Malignancy, pharyngeal pouch, motility & neurological disorders.
AgeHistory
History
Sudden onset: suggests a foreign body Rapid onset: over a period of weeks as In carcinoma Gradual onset: over years as in achalasia and benign strictures
Onset
Motility disorders: dysphagia for liquids and solids Structural disorders: dysphagia for solids only
once a solid bolus becomes impacted,
the patient will report dysphagia for liquids and solids
Solids or liquidsHistory
At the beginning of swallowing: oro-pharyngeal Retrosternal bolus hold-up: esophageal
SiteHistory
Progressive: Neoplastic causes (benign or malignant) Intermittent: Motility disorders
ProgressionHistory
Coughing or choking with swallowing
Difficulty initiating swallowing Food sticking in the throat
Symptoms Mostly to oral- pharyngealHistory
Sialorrhea Recurrent pneumonia Change in voice or speech Nasal regurgitation
Patient's conscious level & mental status Vital signs Examination of cranial nerves V and VII-XII Assessment of voice Examination of neck and chest including assessment
LN Swelling Gurgling or crepitus in Zenker’s diverticulum.
Examination
Direct observation of lip closure, jaw closure, chewing and mastication, tongue mobility, palatal and laryngeal elevation
Inspection the oral cavity and pharynx Examination of gag reflex by stroking the pharyngeal mucosa with a
tongue depressor Direct observation of the act of swallowing
Watch the patient while drinks a water Assess the patient's eating of various food textures
Examination
Skin should be examined for features of connective tissue disorders, particularly scleroderma
Signs of malnutrition, weight loss and pulmonary complications from aspiration should be looked for
Examination
Investigations
Infectious or inflammatory conditions Nutritional status Fluid-electrolyte imbalance Thyroid function - in detecting dysphagia associated with
hypothyroidism or hyperthyroidism
Laboratory
FB
X-rayRadiological
Aspiration Pneumonia Retrophary widening
Barium SwallowRadiological
Endoscopy
1. Direct laryngoscopy
2. Flexible nasopharyngoscopy
3. Bronchoscopy
4. Oesophago –gastro -dudenoscopy {OGD} is the first-line investigation for almost all upper GI symptoms
Endoscopy Diagnostic:
Give direct Visualizations Permits biopsy Endoscopic Ultrasound {EUS}
Therapeutic: Dilatation of strictures Insertion of stents Thermal ablation of tumors Removal of foreign bodies Control of bleeding
Endoscopy
EUS is mostly used for staging for oesophagogastric cancer.
Used to allow fine needle biopsy of suspicious lymph nodes.
Endoscopy
Special Tests
Definitive study for evaluation of the swallowing mechanism
Uses different barium consistencies and simulated foods
Assess pharyngeal anatomy and motility and may evaluates all phases of swallowing
Modified Barium Swallow (MBS)
Esophageal Manometry
For Motility Disorders
Inadequate relaxation of the LES – Achalasia
Uncoordinated contractions – Diffuse
Esophageal Spasm (DES)
Hypocontraction – Ineffective motility
Esophageal pH Monitoring
Diagnosing GERD A nasogastric probe is inserted into the
patient's esophagus to record ph. levels These levels are compared with the patient's
record of symptoms over 24 hours to determine whether acid reflux contributes to his/her symptoms
Management
Evaluation of the severity of dysphagia Avoid dysphagia related complications
Nutritional intake Maximize airway protection
Diagnosis of underling cause Treatment: Medical, conservative , surgically or palliative
Goals of Management {Dysphagia}
Conservative
Dietary modification Training in swallowing
techniques and maneuvers
Management
Entearal feeding
NGT OGT Gastrostomy Jujonostomy
Up to 40- 60 F Hydrostatic or pneumatic Indications –
Strictures Achalasia Anastomotic stenosis
Esophageal dilatation
Diverticulotomy: diverticulum Myotomy: motility disorders Fundoplication: GERD Esophageal resection &
Reconstruction: Malignancy caustic injuries
Surgery
Self expanding metal stents Sever dysphagia in non resectable
cancer esophagus Complication - stent blockage & stent
erosion
Palliative Stent
DysphagiaDr. Ali M Ahmad
Consultant Pediatric Surgery; MBBCH, MS, MD, MRCS-ED, EBPS
Associate Pediatric Surgery KAAUH_ PNU
Thank You