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E Case 8
SVNGMCYAVATMAL
DEPT. OF PATHOLOGY
CASE HISTORY
• A 33 year old man presented with extensive skin lesions all over body mainly involving face region.
• known case of CML, “Ph” chromosome positive and on imatinib therapy since two years.
• PS examination – WNL.
Photograph showing extensive skin lesion on face.
FNAC smear from : Nodule On Face (MGG).
FNAC smear from skin lesion ( MGG ) .
• Skin biopsy studied showed dermal infiltration by similar cells in upper as well as deeper dermis. Skin adnexal tissue also showed infiltration. • IHC on skin biopsy – cells were found positive for cKit and MPO. •CD34 was found negative.• Background lymphoid cells were found highlighted by CD3. (Images not available)