Far Eastern University Institute of Nursing
Evidence Based NursingJose Reyes Memorial Medical Center BSN113 Group 52 Ms. Analiza DimaanoClinical Instructor
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Comparative Study of Topical Application of Timolol and Verapamil in Patients with Glaucoma within 6 MonthsI. CLINICAL QUESTION
Is there a significant difference between the use of topical Timolol and Verapamil in patients with glaucoma within 6 months application? II. CITATIONComparative Study of Topical Application of Timolol and Verapamil in Patients with Glaucoma Within 6 Months. JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS Volume 25 pp 551-553, Number 6, 2009
III. STUDY CHARACTERISTICS 1. Patients Included The study population consisted of 59 patients; 31 patients were male and 28 were female. The patients age was between 27 to 81 years of age. All 59 patients were diagnosed with glaucoma. 2. Interventions Compared Early in the first step, the IOPs of patients were measured by applanation tonometry and those with the IOP of 23 mmHg and more were chosen for the study. Pachymetry was done to adjust the IOPs. 3. Outcome Monitored Using the same measuring procedure (applanation tonometry), intraocular pressure was measured again after 90 min and was recorded in the file with mentioning which drug (A or B) was used. Finally the data were collected and analyzed. 4. Does the study focus on a significant problem in clinical practice? Yes, the study absolutely focuses on a significant problem in the clinical setting. The study can be one of the key in the treatment of glaucoma patients. Losing ones sense of sight would not be a happy thing. It is a fact that glaucoma is the third reason of blindness around the world. According to the World Health Organization, it is about 2.4 millions of people around the world who suffer this disease and 15% of these cases lead to blindness. This study offers a hand and a supplement in the appropriate management of glaucoma cases thus significantly decreases the cases of glaucoma leading to blindness.
IV. METHODOLOGY AND DESIGN 1. Methodology UsedBSN113 Group 52 Evidence Based Nursing
Page 3 of 5The patients were divided into 2 groups; the first group with 30 patients and the second with the remaining 29 patients. Informed consents were obtained and the research was approved by the institutional review board. The research was based on the tenets of the Declaration of Helsinki, as it was a clinical trial study on patients with glaucoma. The researchers used SPSS v.15 and P value was defined significant