EbolaThe Deadly African Virus

http://www.youtube.com/watch?v=aE69K_lP2ug (2min)

Virus Classification

Group: Group V (-)ssRNA Order:Mononegavirales

Family:Filoviridae Genus:Ebolavirus

History

Outbreaks

Outbreaks Continued

Summary of Lethality

Possible Origin?

Transmission/Target Groups

Tissue/Organ Damage Methods Pro-Inflammatory Cytokines –

promotes systemic inflammation Coagulation (thrombogenesis) is the

process by which blood forms clots.

Incubation Period From 2-21 Days Early Symptoms Severe headache Weakness Muscle aches

Delayed Symptoms Severe vomiting Abdominal pain Diarrhea Pharyngitis (throat

inflammation) Conjunctivitis (Pink

Eye) External bleeding Extremely high body

temperature Prostration

Unfortunate Result

Diagnosis/Laboratory Testing ELISA- The enzyme-linked

immunosorbent assay (ELISA) is a test that uses antibodies and color change to identify a substance

The polymerase chain reaction (PCR) is a biochemical technology that generates thousands to millions of copies of a particular DNA sequence

THERE IS NO CURE FOR EBOLA

Safety Precautions

Future Outlook

Citations“Ebola Hemorrhagic Fever.” Special Pathogens Branch: Diseases.

Nov. 26, 2003. Center for Disease Control and Prevention. 3/19/04 <http://www.cdc.gov/ncidod/dvrd/spb/mnpages/dispages/ebola.htm>

Murphy, Frederick A. “Ebola Virus.” Encarta. CD-ROM. Microsoft, 2002

Russell, Brett. Ebola Information. 3/19/04 <http://www.brettrussell.com/personal/ebola.html>

Col. Weeks, Byron, M.D. “Ebola – A Serious Threat.” NewsMax.com. Oct. 17, 2001. 3/19/04 <http://www.newsmax.com/archives/articles/2001/10/12/82239.shtml>

Citations Continued http://www.cdc.gov/ncidod/dvrd/spb/mnpages/

dispages/ebotabl.htm http://www.who.int/mediacentre/factsheets/fs103/

en/ Hampton, Tracy. Vaccines Against Ebola and

Marburg Viruses Show Promise in Primates Studies. Maedical News and Perspectives. JAMA. Vol. 294 No. 2 July 2005.

Jones, Steven. Live attenuated recombinant vaccine protects nonhuman primates against Ebola and Marburg viruses. Nature Medicine. Vol. 11 No. 7 July 2005.