Educating the Scientist

EntrepreneurStefano Fantoni, SISSA Trieste

International School of Advanced Studies

spin-off companies

worldwide network

english language

new initiatives and projects

entreprenurial culture

scientific excellence

dynamic

international PhD school

interdisciplinaryapproach

Connecting Scientific Ideas to Market

Social Network Models

Business Models

Open Cooperative and Community based Social Networks

Concept Vs

Structure

Problems: security, intellectual property, privacy, hierarchy…

How to reach breakthrough innovations

• entrepreneurial mindsets and attitudes

• new approaches and educational models that

• enable the capacity to understand markets and implementation complexity in the real world

• learn from the traditional scientific approach

• learn how to follow multiple pathways 

• work with global scale partners with complementary skills

• better deal with complexity by mobilizing global social networks

SCIENTISTS MANAGERS

Short-circuiting scientists’ mindset to market needs and complexity will contribute to radical innovations in market processes and to the generation of new scientific

paradigms.

Entrepreunership: recognize opportunity!

Open, cooperative, and community based “Business” Models ------

Computer 1948 (ENIAC)

Internet 1983 (TCP/IP)

WWW 1980 (CERN)

Electronic publications 1992 (SISSA)

Citation Index => Link Ranking => Google 1996 (Stanford, PhD thesis)

Web 2.0 now

…… future

Scientists Entrepreneurs

recognize opportunities and create new business models

work at knowledge borderlines

Italian community for computer simulation at nano scale level.

Theoretical a numerical support to chemistry and physics large-scale facilities.

Ideal environment for innovative ideas in numerical simulations

R&D in HPC methods and systems (parallel, cluster, and grid computing)

DEMOCRITOS

www.democritos.it

Mission

9 institutions (Universities, laboratories)

1 office in ELETTRA laboratory4 research activities + 1 R&D

service in IT70 researchers (45 university

researchers) 40 PhD students and 20

postdoc4 amministrative employee200 years cpu time / year>100 high impact publications

/ year

NumbersComputational nanoscience

and materials engineering

Computational biochemistry, biotechnology, and drug design

Hard and soft condensed matter: superconductivity and disordered systems

IT for computer simulations: software engineering, parallel, cluster, and grid computing

Research

Democritos

Catalysis Material

Ethylene Epoxidation

QUANTUM ESPRESSO

LausanneMIT, Boston

Princeton

Minneapolis SISSA-Democritos,TriesteParis

a world-wide connected project…

…for materials modeling at the nanoscale….

..by computer simulations

Designing a new business model

product evaluation

competitors study

market mapping

financial analysis

extend analysisin the future

üThe guide-lines• open model• community-based (QE)

Scientific community

üThe core:• HPC/IT technologies • materials design OS project

Scientific accelerator Market

üMarket approach• use the community• world-wide network

…done…and to be done..

Developed by: S. Baroni, G. Chiarotti, S. Cozzini, S. Paolini

ICT at SISSA: eLab• in collaboration with CNR/INFM Democritos National Simulation Center • it leverages on the long standing experience in High Performance Scientific Computing

developed so far. • The term e-Science (or eScience) is used to describe computationally intensive science that

is carried out in highly distributed network environment. [from wikipedia]

Maintaining a cutting-edge computational infrastructure for research groups at SISSA and DEMOCRITOS

Plan and setup advanced solution for scientific and technical computing

• Software engineering• Parallel computing (platforms &

algorithms)• Cluster computing (high-performance

and distributed)• Grid computing

Enable technological transfer toward industry on the above theme Technology and products

The mission The activities

• Cooperating with Eurotech on setting-up a HPC/Grid-environment for SME in FVG (MercurioFVG as promoter)

The proposal:• create a collaborative environment

among research institution and industry • Setup of a common infrastructure• Identify industrial technical problems to

run o on the infrastructure • Create “human capital”

Sissa MedialabSissa Medialab's scholarly publishing activities date back to the early 1990's when, in the pre-Web era, SISSA set up the first electronic e-print service in Europe with the Babbage archive. Just a few years on, this was to trigger the idea of setting up JHEP (Journal of High Energy Physics) an online-only journal for high energy physicists that would revolutionise publishing habits in that community.

Sissa Medialab is an active player in the arena of science communication to the general public, using different media aimed at different audiences, with a network of over 600 scientists. Using the web, Sissa Medialab reaches out to the general public – ranging from children to scientists – in order to impart scientific knowledge in a spirit of dialogue and debate.

Lubricant molecular structure

NeuroTelemetryMathew E. DIAMOND, Erik ZORZIN, Igor PERKONSISSA - Cognitive Neuroscience Sector - Tactile Perception & Learning Laboratory

http://www.sissa.it/cns/tactile

NeuroTelemetry is a brain-computer interface device designed at SISSA, capable of capturing signals generated by neurons and transmitting them via radio to a remote computer using a wireless digital technology.

RoboticsClinic stimulation

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Health monitoring

Fields of application:

Neuron

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101…

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Audio technology

Patent Pending #PD2006A000348

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promoscienceThe experience of a university spin-off

University Spin off Global company

RESEARCHRESEARCH

PublicationsKnow-howResultsCompetencies

PRODUCT/PRODUCT/SERVICE SERVICE

DEVELOPMENTDEVELOPMENTProduct prototype Market driven customizationProduct introduction to the

marketDissemination

Innovation centers

Public fundsConsultants

MARKET SEGMENT MARKET SEGMENT LEADERSHIP LEADERSHIP

POSITIONPOSITIONProduct marketingProduct updates

Product differentiation

ProfessorsResearchersStudents

A Content Management tool for scientific dissemination

A Project Management tool to support the management of scientific projects

?promoscience experience:

Competencies:- Information Retrieval Systems- Current Research Information Systems- Virtual Document Systems- GUI Design- …

++

Glance Vision Tech. Srl

Innovative morphological analysis tool

PRODUCTS

Self-learning tool for analysis of biological images

application: ROBOTICS(e.g. frame painting)

established in 2005spin-off company

Computer Vision & Machine Learning

face new problems in a possibly original way

solid scientific background

Research as the key factor for

competitiveness

GET TO MARKET FASTER: FROM GENE TO ANTIBODIES

Italian private biotech company

Focus on CNS (Alzheimer’s disease) and other neurological disorders (pain)

Proprietary antibody- based technology platform constantly generating new therapeutic opportunities

Novel animal models for neurodegenerative and aging-related diseases

Pipeline of innovative compounds in advanced preclinical stage

SPLINT is LLG proprietary platform for the selection of superior quality antibodies directly from gene sequences, with no requirement for protein expression, thus removing a severe bottleneck in the procedures for antibody isolation with other existing methods.

The solution for the non invasive delivery of NGF to the brain

The therapeutic concept that NGF might be used to slow or prevent cholinergic neuronal death in Alzheimer’s disease (AD) is an emerging theme, probably one of the most promising avenues to pursue.

After having obtained the first PoC for a non invasive delivery of NGF to the brain, LLG has developed a proprietary form of NGF as a viable option to cure neurodegeneration.

Lay Line Genomics

SISSA-Elettra Nano Innovation Laboratory

The Sissa-Elettra Nano Inovation Laboratory (SENIL) in collaboration with CBM is developing breakthrough technologies that aim at

These new technologies are based on an our ability to measure molecular heights with unprecedented precision coupled to the ability to nanopattern soft materials on an equally unprecedented small scale.

quantitative determination of gene expression

single cell DNA analysis

detection of protein biomarkers with ultra high sensitivity down to the

subpicomolar concentration regime

Finance Portfolio Optimization

Developed by: C. Reina

Non standard Perturbed Gaussian Model for Portfolio Variance Optimization

Better middle term returns!

Integrating Scientific Creativity, Enterpreunership and Business

Processes

Five key themes

Emerging technologies in IT, material science, biotech,

energyidea generation and solution

identification (physics, genetics, evolution, neurosciences)

Opportunity and potential customer needs

and trends

Entrepreneurial, leadership, personal and team-working skills

Implementation processes (project management, organization,

operative flow, HR, mkt, )

Developed by: G. Chiarotti, M. Fuccaro, P. Focher, E. Quadrelli, A. Sfiligoj

New paradigsm needed?

[…...] the issue is whether we can succeed in developing new strategies for combining reductionist and holistic approaches in order to provide a meaningful bridge between molecular mechanism and mental processes: a true molecular biology cognition. If this approach is successful in the twenty first century, we may have a new, unified, and intellectually satisfying view of mental processes.

CELL - Thomas D. Albright, Thomas M. Jessell, Eric R. Kandel and Michael I. Posner