Text to be added The EFFORT consortium is made up of 20 partners from 10 European coun- tries, representing different sectors (e.g. public institutions, academia, re- search, industry) working on the antimicrobial resistance topic. Partners Contact us www.effort-against-amr.eu Coordinator Prof. Jaap Wagenaar Utrecht University The Netherlands effort-offi[email protected]Media Contact Prof. Katharina Stärk SAFOSO Switzerland [email protected]Ecology from Farm to Fork Of microbial drug Resistance and Transmission (EFFORT) EFFORT (Ecology from Farm to Fork Of microbial drug Resistance and Trans- mission) is supported by the European Commission under the Food, Agriculture and Fisheries, and Biotechnologies theme of the 7 th Framework Programme for Research and Technological Development (Grant Agreement no 613754). Utrecht University (UUVM), NL French Agency for Food, Environmental and Occupa- tional Health & Safety (ANSES), FR Federal Institute for Risk Assessment (BFR), DE SAFOSO AG – Safe Food Solutions (SAFOSO), CH Wageningen University (BEC), NL Vetworks BVBA (Vetworks), BE Porq BV (PORQ), NL Jørgen Lindahl/ Ø-Vet Aps (Ø-Vet), DK ILSI Europe (ILSI), BE Technical University of Denmark (DTU), DK VION Food Group (VION), NL Intomics A/S (Intomics), DK Arttic (ARTTIC), FR Ghent University (UGent), BE Bulgarian Food Safety Agency (NDRVI), BG Central Veterinary Institute (CVI), NL Istituto Zooprofilat- tico Sperimentale delle Regioni Lazio e Toscana (IZSLT), IT National Veterinary Institute (NVRI), PL University of Vet- erinary Medicine Hannover (TIHO), DE Complutense University of Madrid (UCM), ES www.effort-against-amr.eu
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The EFFORT consortium is made up of 20 partners from 10 European coun-tries, representing different sectors (e.g. public institutions, academia, re-search, industry) working on the antimicrobial resistance topic.
Media ContactProf. Katharina StärkSAFOSOSwitzerland [email protected]
Ecology from Farm to Fork Of microbial drug Resistance and Transmission
(EFFORT)
EFFORT (Ecology from Farm to Fork Of microbial drug Resistance and Trans-mission) is supported by the European Commission under the Food, Agriculture and Fisheries, and Biotechnologies theme of the 7th Framework Programme for Research and Technological Development (Grant Agreement no 613754).
Utrecht University (UUVM), NL
French Agency for Food, Environmental and Occupa-
tional Health & Safety (ANSES), FR
Federal Institute for Risk Assessment (BFR), DE
SAFOSO AG– Safe Food Solutions
(SAFOSO), CH
Wageningen University (BEC), NL
Vetworks BVBA (Vetworks), BE
Porq BV (PORQ), NL
Jørgen Lindahl/Ø-Vet Aps
(Ø-Vet), DK
ILSI Europe (ILSI), BE
Technical University of Denmark (DTU), DK
VION Food Group
(VION), NL
Intomics A/S (Intomics), DK
Arttic (ARTTIC), FR
Ghent University(UGent), BE
Bulgarian Food Safety Agency (NDRVI), BG
Central Veterinary Institute (CVI), NL
Istituto Zooprofilat-tico Sperimentale
delle Regioni Lazio e Toscana (IZSLT), IT
National Veterinary Institute
(NVRI), PL
University of Vet-erinary Medicine
Hannover (TIHO), DE
Complutense University of Madrid (UCM), ES
www.effort-against-amr.eu
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EFFORT is an EU-FP7 5 years project (2013-2018), led by Prof. Jaap Wagenaar, Utrecht University (The Netherlands). The consortium of 20 partners from 10 European countries is studying the complex ep-idemiology and ecology of antimicrobial resistance (AMR) and the interactions between bacterial communities, commensals and patho-gens in animals, the food chain and the environment.
Objectives
• Understanding the epidemiology of antimicrobial resistance in the food chain.
• Understanding the ecology of antimicrobial resistance in the microbial communities.
• Understanding the relative contribu-tion of the exposure routes of anti-microbial resistance from animals to humans.
• Understanding the economic impact and animal welfare aspects of antimi-crobial resistance in the food chain.
About the EFFORT project
Knowledge production in EFFORT is structured into 8 interrelated scientific work packages (WPs) and 2 WPs on knowledge translation.
These WPs include a combination of epidemiological and ecological stud-ies, using newly developed molecular and bioinformatics technologies, go-ing therefore beyond previous related research projects. EFFORT will include an exposure as-sessment of humans from animal and environmental sources. The ecologi-cal studies on isolates will be verified by in vitro and in vivo studies.
Moreover, real-life intervention stud-ies will be conducted with the aim of reducing the use of antimicrobials in veterinary practice. The economic im-pact of antimicrobial resistance in the food chain will also be evaluated. Finally, the different sources of infor-mation will be used in our prediction models, with the overall goal of lim-iting the future evolution, in humans, of resistance to the most critically im-portant antimicrobials.
Activities
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Expected outcomes
EFFORT expected outcomes include the answers to the following fundamen-tal, but complex questions demanded by risk managers:
• What is the impact of antimi-crobial usage in food-producing animals on human exposure to AMR determinants?
• What are the most important transmission routes and sources of human exposure to AMR de-terminants?
• What is the impact on human health of the transfer of AMR de-terminants between commensals and pathogenic microorganisms?
• How can human exposure to AMR determinants through food-producing animals be re-duced?
• What is the most cost-effective way of monitoring antimicro-bial resistance occurrence in food-producing animals and in the food chain?
EFFORT results will support future evidence based pol-icies, and the prioritisation of risk management options along the food chain, relat-ed with antimicrobial re-sistance, one of the major threats to the global public health.
Project activities include epidemiological studies, sample analysis and data analysis involving food animals, wildlife, companion animals, humans and the environment.
