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Electrocardiography (ECG) and blood...

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Electrocardiography (ECG) and blood pressure Élettani és Neurobiológiai Tanszék EKG gyakorlat
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  • Electrocardiography (ECG) and blood pressure

    Élettani és Neurobiológiai Tanszék

    EKG gyakorlat

  • Human circulation pulmonary circulation

    left

    right atrium

    right

    right ventricule

    atrium

    left

    left ventricule

    Élettani és Neurobiológiai Tanszék

    systemic circulation

    EKG gyakorlat

  • right atrium Cross-section of the human heart

    left atrium

    bicuspid valves

    right ventricule

    left ventricule

    Élettani és Neurobiológiai Tanszék

    EKG gyakorlat

  • Conduction system of the heart Frontal plane

    Left atrium

    Right atrium

    1 SINOATRIAL (SA) NODE 2 ATRIOVENTRICULAR (AV) NODE

    3 ATRIOVENTRICULAR (AV) BUNDLE (BUNDLE OF HIS)

    4 RIGHT AND LEFT BUNDLE BRANCHES

    Right ventricle

    5 PURKINJE FIBERS

    Élettani és Neurobiológiai Tanszék

    Left ventricle

    EKG gyakorlat

  • Einthoven 1895: description of the characteristic ECG waves 1912: declaration of the Einthoven triangle 1924: Nobel Prize

    Élettani és Neurobiológiai Tanszék

  • Standard ECG recording

    • human body is a good volume conductor (~70% contains water and ions) -> electrical activity generated by the heart can be recorded on the

    surface of the skin: electrocardiography (ECG)

    • characteristic waves during a heart cycle: P wave, QRS complex, T wave • provides information about: - generation and conduction of

    action potentials; heart rate - problems with pacemaker activity - loss / damage to the conductive system or to cardiac muscle (myocardial infarct)

    • does NOT provide information about: - pressure changes, ejected blood

    volumes, force generated by cardiac muscle, etc

    Élettani és Neurobiológiai Tanszék

  • Cardiac cycle

    1 Depolarization of atrial contractile fibers

    produces P wave

    events and the

    electrocardio- gram (ECG)

    6 Ve6ntricular diastole (relaxation)

    P

    0 0.2 0.4 0.6 Seconds

    5 Repolarization of5 ventricular contractile

    fibers produces T wave

    T

    P

    Action potential in SA node

    0 0.2

    Seconds

    0.8

    2 Atrial systole (contraction)

    P

    0 0.2 Seconds

    3 Depolarization of ventricular contractile

    fibers produces QRS complex

    Élettani és Neurobiológiai Tanszék

    P

    4 Ventricular 0 0.2 0.4 0.6 systole

    Seconds (contraction)

    P

    0 0.2 0.4 Seconds

    R

    P

    Q S

    0 0.2 0.4 Seconds

    EKG gyakorlat

  • Standard ECG recording

    atrial contraction

    ventricular contraction

    ventricular repolarization

    atrial depolarization

    ventricular depolarization

    Élettani és Neurobiológiai Tanszék

    (and atrial repolarization) EKG gyakorlat

  • Unipolar ECG leads

    aVR aVL

    V1 V2 V3

    V4 V5 V6

    6 unipolar chest leads (Wilson type)

    aVF

    3 unipolar (Goldberger-type) limb leads

    + V

    aVR

    1

    V6 -

    6 V2

    2 V55

    V3 V4

    3 4 aVL

    aVF

    + -

    + -

    Élettani és Neurobiológiai Tanszék

    EKG gyakorlat

  • Standard bipolar ECG leads (Einthoven type)

    right arm

    I

    right leg

    right arm

    II

    right leg

    III

    right leg

    left arm

    left leg

    left arm

    left leg

    + -

    + -

    + -

    Élettani és Neurobiológiai Tanszék

    EKG gyakorlat

  • Einthoven's law and the mean electrical

    axis of the heart

    Lead I + Lead III = Lead II

    É

    right arm

    II

    I -+

    III

    left leg

    left arm mm

    - -

    mm

    II +

    I

    + -

    mm

    + III

  • How to plot the mean electrical axis of

    the heart?

    Élettani és Neurobiológiai Tanszék

    EKG gyakorlat

  • Deviations in the mean electrical axis of

    the heart

    Élettani és Neurobiológiai Tanszék

    EKG gyakorlat

  • Characteristic ECG curves Normal sinus arrhythmia (respiratory sinus arrhythmia)

    inhalation

    22 years

    79 years

    time (s)

    Élettani és Neurobiológiai Tanszék

    EKG gyakorlat

  • Extrasystole

    atrial

    sinoatrial

    ventricular

    repeated ventricular

    Élettani és Neurobiológiai Tanszék

    early, abnormal P wave

    early P wave

    long, deformed QRS

    EKG gyakorlat

  • Abnormal arrhythmias

    atrial flutter (200-300 bpm)

    atrial fibrillation

    (300-500 bpm)

    ventricular flutter

    ventricular

    fibrillation

    Élettani és Neurobiológiai Tanszék

    EKG gyakorlat

  • Infarct

    early

    1-6 h

    2-3 weeks

    3-5 months

    Élettani és Neurobiológiai Tanszék

    • elevated T wave

    • unidirectional elevation • decreased Q, R amplitude

    • negative T wave • increased Q amplitude • decreased R amplitude

    • large Q (>1/3 QRS ampl.) • positive T wave • normal R amplitude • normal ST period

    Pacemaker

    EKG gyakorlat

  • Regulation of cardiovascular activity nervous system:

    hormones:

    • epinephrine, norepinephrine, thyroid hormon: increase heart rate and contractility cations:

    • K+, Na+, Ca2+ plasma levels influence contractility

    Élettani és Neurobiológiai Tanszék

    EKG gyakorlat

  • Baroreceptors in the human body and

    innervation of the heart

    Élettani és Neurobiológiai Tanszék

    EKG gyakorlat

  • Regulation of blood

    pressure via

    baroreceptor reflexes

    Élettani és Neurobiológiai Tanszék

  • Blood pressure measurement

    Élettani és

    yakorlat

  • Tasks during the practicum

    Élettani és Neurobiológiai Tanszék

    EKG gyakorlat

  • ECG I (Lesson 5)

    Effects of breathing, physical activity and circulatory reflexes on heart function

    Carry out short (20-30 sec) ECG recordings in the following order:

    1. Baseline registration (seated, normal breathing activity) 2. Seated, deep inhalation - deep exhalation (respiratory arrhythmia) • don't forget to mark the onset of inspiration on the recordings (F9)

    • recording should last at least for two complete respiratory cycles

    4. Immediately before and after physical activity (in sitting position)

    3. Before, during and after sudden stand-up from lying position

    Élettani és Neurobiológiai Tanszék

    EKG gyakorlat

  • Blood pressure

    Define your blood pressure (systolic / diastolic) and pulse rate on your left arm :

    1. lying down 2. sitting 3. standing 4. before and after exercise (e.g. 20 push-ups)

    Élettani és Neurobiológiai Tanszék

    EKG gyakorlat

    Effects of body postures and physical activity on circulation


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