Emerging Hot Topics in Milk Science
Danielle G. Lemay, PhDGenome Center
University of California-DavisOctober 26, 2015
Overview
• IMGC’s e-newsletter: “SPLASH! milk science update”
• This year’s most popular topics• Fun facts about SPLASH!
– Who writes it– Who reads it
• Emerging hot topics for next year and beyond
IMGC’s monthly e-newsletter
SPLASH! content on IMGC websitehttp://milkgenomics.org
Many ways to subscribe
• Attend an IMGC Symposium (we’ll add you)
• Text SPLASHMILK to 22828 (in the U.S.)
• Click on “Join our mailing list” in a forwarded e-newsletter
• Join on milkgenomics.org• Email [email protected]
Number of Articles Published in SPLASH!
Which articles were the most popular in 2015?
Readers love a controversy
• Association != Causality• Hypothesis: milk-drinking and non-drinking subjects have different
genetic backgrounds that influence their health independent of milk consumption
Novel benefits of cow’s milk
More benefits of human milk oligosaccharides
• Feed beneficial gut bacteria• Act as decoys for pathogenic bacteria• Reduce inflammation in intestines
Microbes and milk
Changing views on dairy fat
New technologies
Molecular signals in milk
Mammary gland epigenetics
Can we find the jewels in the junk DNA?
See talk by Dr. Monique Rijnkelson Tuesday morning
Human milk as a commodity
Improving milk production with genetics
Comparing Mammals
http://milkgenomics.org/newsletter-archive
Cow’s milk ingredients improve infant formula
Dr. Bing Wang will talk about lactoferrin and cognition Tuesday afternoon
Control of cow’s milk fat composition
Benefits of dairy for metabolic health
Explore synergistic opportunities
Accelerate progress
Goal: Something for everyone
SPLASH! Editorial Team (2015)
Prof. Foteini Kakulas
Prof. Peter Williamson
Dr. Lauren Newmark
Prof. Katie Hinde
Dr. Lillian SandoAnna Petherick
Dr. Danielle Lemay
Dr. SandeepRavindran
IMGC Impact: SPLASH newsletter
ConferenceAttendees
NewsletterSubscribers
Number of People
ConferenceAttendees
NewsletterSubscribers
Number of People
WebsiteVisitors
IMGC Impact: SPLASH online
NEW VISITORS RETURNING
For every 1 person attending the conference,6,000 people are visiting the website.
SPLASH! content online
82,266 page views
Sept 2014-2015
Average time spent on a page?
2.15 minutes
How do people reach SPLASH content?
Over 2000 Facebook shares!
Who is reading SPLASH?
Top countries: US, India, UK, Australia, Canada, Denmark, New Zealand, Phillipines, Netherlands, Germany
Who is reading SPLASH?
Top cities: New Dehli, London, Melbourne, Sydney, New York
Future
Beneficial effects of dairy
• Cardiovascular disease • Metabolic disease• Weight loss & body composition• Bone health• New! Role of dairy in healthy aging • New! Health effects of milk fat• New! Effects of dairy on inflammation• New! Effects of dairy on gut health
New tools to help farmers select most profitable cows
• Improvements in genomic selection of dairy cattle• New tools for assessing phenotypes
– Scanning milk samples with mid-infrared spectrometry– On-farm sensors to monitor cows
Learn about new methods today with talks by Dr. Cameron Clark, Dr. Toni Reverter, and Mary Abdelsayed
Milk Production, Sustainability, & Food Choices
Cows are part of the solution!
For more about the web of food choices,stay for the talks on Wednesday morning by Dr. Stephen Simpson and Dr. David Raubenheimer
For improving milk production, see talks by Dr. Peter Thomson and Dr. Peter Williamson on Tuesday AM
Milk microRNAs
• What are they? Do they survive milk processing?• Do they survive digestion?• Do they affect the consumer?
See talks on Tuesday afternoon!
Dr. Christophe LefevreDr. Meagan Gillespie
Milk miRNA expression, transfer, and effects of milk processing
Milk and offspring development
• Acquisition of tolerance of self, food, microbes
Talk on Wednesday morning by Dr. Bernd Stahl
Milk and offspring development
• Metabolic programming
Talk at noon today by Dr. Jennie Brand-Miller
Talk on Wednesday morning by Dr. Ross Tellam
Immunity
Viruses and (human) milk
• CMV• HIV• Rotavirus• RSV• Retroviruses• Bacteriophages
Bovine milk exosomes
• What are they? How does nature use them? How might we use them?
• A flavor delivery system?• A drug delivery system?
What would Dr. van de Loo do?See his exciting talk next!
Peptides in milk
See talk by Dr. David Dallason Tuesday afternoon
Anti-fungal? Prebiotic?
Milk glycans & gut bacteria
• What is the fate of milk glycans in the gastrointestinal tract?
• Which bacteria consume milk glycans?• What is the impact on the host?
See talk this afternoon by Dr. Steven Frese
Milk oligosaccharides for infant formula
Who will win the race to full-scale production of diverse milk sugars?• Extraction, purification from bovine milk• Chemo-enzymatic synthesis• Synthesis by genetically engineered microbes
http://milkgenomics.org/newsletter
Synbiotics: bovine milk and probiotics
• Human milk and gut microbes co-evolved• Many human milk components are in cow’s milk• Are there specific bovine milk components and
specific probiotics that together (synbiotics) have beneficial effects on the host?
Tuesday afternoon talk by Dr. Veronique Demers-Mathieuand later this morning by Megan Sanctuary
Novel fermented dairy products
Better control of microbes inmilk production &
processing
Antimicrobial resistance is a growing issueNew methods to monitor microbesNew solutions to control microbes for better safety, longer shelf life
Create the Future
Ideas on how to increase number of subscribers
Send suggestions for topics, feedback, announcements, etc, to Danielle Lemay at [email protected]
AcknowledgmentsASSOCIATE EDITORSAnna PetherickProf. Foteini KakulasProf. Katie HindeDr. Lauren NewmarkDr. Lillian SandoProf. Peter WilliamsonDr. Sandeep Ravindran
Assistance with material for slides: Tasslyn GesterCora MorganErik Kwok Cora Morgan, Tasslyn Gester
FUNDING PROVIDED BY
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