Emphysematous abomasitis in one month
old lambsHein Snyman BVSc
DVSc Anatomic Pathology ResidentDepartment of PathobiologyOntario Veterinary College
University of Guelph
Signalment
• One month old lambs (n=3)
• Male• Rideau Arcott
History• Novice small scale operation• Farmer away on the weekend• Returned to find 3 lambs dead• Acute death within last 36
hours• Growing well
Gross findings
• Good body condition• Fibrinous peritonitis & serosal
petechiae• Abomasal mucosal haemorrhage,
necrosis and ulceration• Exuberant autolysis of the kidney
and liver
Gram + Rods
Ancillary diagnostics• Faecal flotation – NAD• Bacterial culture:
4 + Clostridium perfringens3 + Mannheimia haemolytica
• Clostridial Fluorescent antibody test (FAT)
Clostridium septicum
www.vet.uga.edu
DiagnosisMdx - Emphysematous, necrotizing and suppurative abomasitis, trans mural, regionally extensive, acute.Edx - Clostridial gangrenous abomasitis/BraxyEtiology – Clostridium septicum & C. perfringens
Braxy• Highly fatal• Acute to peracute• Treatment rarely successful• NW Europe
• Norway, Denmark, North Germany, Iceland and the Faroe islands – Bradsot
• UK, Ireland, North America and Australia
Braxy• Low prevalence• Cold winters• Overwintering on
summer pasture• Autumn, early to
mid winter• North America –
early spring
Braxy
• Severe oedema, necrosis and gangrenous inflammation of the mucosa of the abomasum
• C. septicum, C. novyi, C. perfringens type A & C
Braxy
• Good condition• 6 to 18 months• Morbidity up to 50 %• Calves• Abomasal ulcers
Pathogenesis• Poorly understood• Mucosal invasion and proliferation
without any predisposing lesion• Coarse and frozen vegetation• Toxin production• Abomasal canula – Glucose & VFA’s• Centrifugal emphysematous lesions
Ellis T.M., Rowe J.B. and Lloyd J.M. (1983). Acute abomasitis due to Clostridium septicum infection in experimental sheep. Aust. Vet. J. 60, 308-309.
Prevention
• Immunoprophylaxis• Toxoid/Bacterin• No vaccination
protocol• No Clostridial
vaccines
References• Coetzer J.A.W., Tustin R.C. Infectious
diseases of livestock, 2nd Edition, Volume Three, Section Five: Bacterial diseases, 183 Clostidium septicum infections, pg. 1869-1873.
• Ellis T.M., Rowe J.B. and Lloyd J.M. (1983). Acute abomasitis due to Clostridium septicum infection in experimental sheep. Aust. Vet. J. 60, 308-309.
• Eustis S.L. and Bergeland M.E. (1981). Suppurative abomasitis associated with Clostridium septicum infection. J. Am. Vet. Med. Assoc. 178, 732-734.
• Songer JG. (1996). Clostridial enteric diseases of domestic animals. Clin. Microbiol. Rev. 9, 216-234.