Exercise Induced Pulmonary

Hemorrhaging creates

bleeding in lungsEIPHExercise Induced Pulmonary Hemorrhaging

Causes of EIPH

Locomotor Respiratory Coupling causesbursting capillariesPrevious lung damagePrevious EIPH

EIPH ismonitoredby...

Subjectivescoring systemfrom 1-5

will developof US Racehorses

80%EIPH

EIPH must be prevented to continue racing

Furosemide (Lasix)

Legalized for USRacetracks in 1995

Also known as LasixUsed to prevent fluid buildup in lungs

Lasix reduces

fluid by

11-13%11.6 cases

Lasix dropped EIPHcases from 58 to

**Furosemide is usedto prevent and treatEIPH**

Is Lasix

EFFECTIVE

for EIPH?

No improvementin track times

Dehydration of fluidReduction causesunfair weightadvantage

Potential DrugMasking Abilities

More evidence showsheritability of EIPHwhich is covered bythe use of Lasix.. Thiscan cause selection ofEIPH gene. Increaseneed for Lasix.

Hinchcliff, K. et al. 2009. Efficacy of Furosemide for Prevention of Exercise-Induced

Pulmonary Hemorrhage in Thoroughbred Racehorses. JAVMA. Vol. 235: 76-82.