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Curriculum Vitae Andrea Ruzzenente

INFORMAZIONI PERSONALI Andrea Ruzzenente

Via Verdi 5a, Negrar, (VR), Italia 37024

+390457514451 +393385850255

[email protected]

Genere Maschile | Data di Nascita 18/06/1973 | Nazionalità Italiana

Luogo di Nascita Verona | CF RZZNDR73H18L781E

ESPERIENZE LAVORATIVE

2017- presente Professore Associato Università dedli studi di VeronaChirurgia generale ed epatobiliare

2008 -Presente Dirigente medico Ospedaliero I Livello Azienda Ospedaliera Universitaria Integrata di VeronaChirurgia generale ed epatobiliare

2006 -2008 Assegno di ricerca

Università degli studi di Verona,

Dipartimento di Scienze Chirurgiche e Anestesiologiche

2004 -2006 Medico Frequentatore

I Chirurgia Clinicizzata, Azienda Ospedaliera di Verona

© European Union, 2002-2013 | http://europass.cedefop.europa.eu Page 1 / 25


ISTRUZIONE

2013-2014 Master universitario di II livello in chirurgia robotica avanzata epato-pancreatica e trapiantologicaUniversità di Pisa, Italia

2009-2012 Dottorato di ricerca in scienze chirurgiche e malattie epato-biliari e pancreaticheScuola di dottorato in Scienze biomediche traslazionali – ciclo XXIX/2009 Università degli Studi di Verona

1998-2004 Specializzazione in chirurgia generale - indirizzo d’urgenzaUniversità di Verona – Votazione 50/50 con lode

1992-1998 Laurea in medicina e chirurgia

Università di Verona – Votazione 110/110 con lode

ALTRI TITOLI

2015 Visiting researcher Division of Surgical Oncology of NagoyaUniversità di Nagoya, Giappone

2014 Advanced Laparoscopic Liver Surgery 2014 Course Università di Gent, Belgio

2014 NET Materclass Londra, UK

2012 IHPBA – postgraduate course – mini-invasive HPB surgeryParigi - Francia

2011 Advanced Robotic COLORECTAL - HPB - ENDOCRINE CourseGrosseto - Italia

2008-2009 European University Diploma - Hepatic-pancreatic and biliary cancers : oncosurgical strategiesUniversità di Parigi Sud XI - Francia

2003-2004 European Hesperis Diploma – European Society of Organ Transplantation



ATTIVITA’ DIDATTICA

2007 – ad oggi Attività didattica del corso di Laurea di Medicina e Chirurgia dell’Università degli Studi di Verona2007/08 ad oggi coadiuvatore dell’attività didattica per l’insegnamento di clinica chirurgica

2007/08 ad oggi docente del corso elettivo “Aspetti di epatologia medica e chirurgica”

2008/09 ad oggi docente corso elettivo “Chirurgia delle vie biliari intra ed extra epatiche”

2008/09 ad oggi docente corso elettivo “Chirurgia del pancreas e dell’area periampollare e problematiche postoperatorie”

2008/09 ad oggi docente del corso elettivo “La chirurgia epatica: dalla preparazione del paziente, all’intervento, al monitoraggio postoperatorio”

2010/2011 ad oggi tutor per l’attività pratica per il Tirocinio professionalizzante di Clinica Chirurgica

2007/2008 ad oggi attività di correlatore di numerose tesi di laurea e di specializzazione in chirurgia generale

2009 – ad oggi Professore a contratto per la scuola di specializzazione in chirurgia generaleUniversità degli Studi di Verona

2010 –ad oggi Docente Tutor Valutatore per gli Esami di Stato per l’abilitazione all’esercizio della professione sanitaria di Medico Chirurgo

2012 – ad oggi Docente dei master universitari dell’Università degli studi di Verona2012- ad oggi docente del master universitario di II livello “Chirurgia epato-pancreatico biliare”

2015-ad oggi docente del master universitario di II livello “Ecografia interventistica oncologica”


2016 – ad oggi Docente della Scuola Italiana di Chirugia Mini-Invasiva (IGoMils)


ATTIVITA’ DI RICERCA

2009 – ad oggi Coordinatore locale di trials clinici multicentrici - Epigenetics in liver cancer (ET study Prot. ET 001, Prot. 15295 del 16/4/2009, Prog.

N. 1647, approved and Prot. N. 5486 of 4/2/2010 emendament N.1 27/11/2009, Prog. N. 1647

- Bayer SPACE (Study Number: 12918): "A phase II randomized, double-blind, placebo- controlled study of sorafenib or placebo in combination with transarterial chemoembolization (TACE) performed with DC Bead and doxorubicin for intermediate stage hepatocellular carcinoma (HCC)"- EudraCT n. 2008-005056-24.

- Studio clinico multicentrico internazionale “Protocol BR1-129 – Quantitative evaluation of SONOVUE enhanced ultrasonography in assessing early response oh hepatocellular carcinoma to sorafenib treatment: a phase II explorative, intra-patients comparative study versus contrast enhanced CT/MRI imaging”

- Studio "ASTRO" ONC-2009-002 (Sorafenib after TACE)- Studio “STELLA – Sorafenib Treatment modalities for HEpatoceLLular carcinoma

patients in itAly. X1110IT - Impact nr. 16028- Studio Bayer HCC 15982 Resorce “A randomized, double blind, placebo-con-

trolled, multicenter phase III study of regorafenib in patients with hepatocellular carcinoma (HCC) after sorafenib”

2000 – ad oggi 179 Pubblicazioni scientifiche

84 articoli su riviste peer review indicizzate su index medicus con IF totale di 379,8

1881 citazioni, h index 23 (SCOPUS);

2817 citazioni h Index: 27 i10index: 42 (Google Scholar)

81 abstract pubblicate su riviste internazionali

12 capitoli di libro

2 libri


2009 – ad oggi Attività revisore riviste scientifiche

Medicine (Academic Editor – Editorial Board)

World J gastrointestinal Sugery (Edirorial Board)

British Journal surgeryThe Surgeon

Liver International, Biomarkers

International Journal of surgery Journal of Liver


RELAZIONI SU INVITO

18.2.10 Il modello organizzativo della week surgery” Dalla Necessità di riorganizzare l’ospedale all’opportunità di migliorare l’assistenza (Seriate)

19.2.10 Chirurgia delle metastasi epatiche, New Strategies in the treatment of colo-rectal cancer (Brunico)

1.10.10 La strategia terapeutica nella litiasi intraepatica: evidenze e controversie Approccio multidispliplinare all’ittero ostruttivo (Verona)

23-24.11.10 La chirurgia delle metastasi epatiche - Il cancro del retto oggi: Attualità diagnostiche e terapeutiche (Verona)

26.02.11 L’urgenza in chirurgia- La colecistite acuta - 37° congresso Società chirurgica Tirolo veneta Lombarda (Bressanone)

12-16.4.11 Radiofrequency ablation for HCC - E-AHPBA congress (Cape town – Sud Africa)

16-18.6.11 Epatocarcinoma: chirurgia vs radiofrequenza - IX Congresso nazionale della società Italiana dei chirurghi universitari (Siena)

25.02.12 Treatment of liver metastases - 38° congresso Società chirurgica Tirolo Veneta Lombarda (Innsbruck)

10.10.13 Il trattamento chirurgico dell’HCC Dall’epatite cronica all’epatocarcinoma (Verona)

13-16.10.13 Le fistole biliari dopo anastomosi biliodigestiva - Congresso nazionale Società Italiana di chirurgia (Torino)

14.12.13 Terapie ablative locali - Nuove frontiere nel trattamento dei tumori del retto (Trento)

15.3.14 Laproscopic liver resections - 40° congresso Società chirurgica Tirolo Veneta Lombarda (Alpbach - Austria)

19-20.4.14 Le recidive del colangiocarcinoma - 7° congresso nazionale it-IHPBA (Bologna)

12-13.9.14 La terapia chirurgica delle metastasi epatiche - Novità e strumenti nella gestione delle neoplasie neuroendocrine (Preganziol)

6-7.11.14 Update nei NET, terapia chirurgica NET fegato - 8° congresso nazionale it-IHPBA (Catania)

21.11.14 La terapia chirurgica HCC - Steatosi epatica non-alcolica (NAFLD) e neoplasie del fegato: una nuova minaccia? (Verona)

4-5.12.14 La chirurgia delle metastasi epatiche - Attualità chirurgiche nel colon-retto (Verona)

26.9.15 La litiasi intraepatica - 40° congresso Società chirurgica Tirolo Veneta Lombarda (Verona)

6.2.15 La terapia chirurgica delle metasatsi epatiche - I tumori neuroendocrini funzionanti di difficile gestione: una sfida terapeutica (Verona)

15-16.12.15 Video nel trattamento mini-invasivo delle metastasi epatiche Attualità chirurgiche nel colon retto (Verona)

4.3.16 La linfoadenectomia nei tumori del fegato - Le linfoadectomie nella chirurgia oncologica tra tradizione ed innovazione (Trento)

9-11.6.16 ICGR15 and FRLV predicting postoperative liver failure - XX annual conference of european


2010 – ad oggi Attività relatore congressi nazionali e internazionali


society of surgery (Napoli) 16.6.2016 Terapia chirurgica delle metastasi epatiche - Congresso società triveneta di chirurgia (Peschiera

del garda VR)

PRESENTAZIONI ORALI A CONGRESSI INTERNAZIONALI

20-25.5.06 Radiofrequency ablation for HCC in cirrhotic patients: Prognostic factors for survival. SSAT-DDW meeting (Los angeles – US)

17-22.5.08 Is liver resection justified in advanced hepatocellular carcinoma? Results of an observational study in 464 patients. SSAT-DDW meeting (San Diego –US)

12-14.4.11 Surgical versus non surgical therapy of HCC on cirrhosis: results of an observational study of 692 cases. 9th congress E-AHPBA (Cape town Sud Africa)

7-11.5.11 Surgical Resection Versus Local Ablation for HCC on Cirrhosis: Results From a Propensity Case-Matched Study. DDW-SSAT (Chicago –US)

1-5.7.12 AGGRESSIVE TREATMENT OF RECURRENCE OF PERI-HILAR AND INTRAHEPATIC CHOLANGIOCARCINOMA AFTER SURGICAL RESECTION CAN IMPROVE LONG TERM SURVIVAL. IHPBA world congress (Parigi, Francia)

29-31.5.13 MUC5AC Novel serum marker for cholangiocarcinoma - 10th congress E-AHPBA (Belgrado)

22-27.3.14 COMPUTED TOMOGRAPHIC PERFUSION (CTP) OF THE LIVER: A NEW NON-INVASIVE LIVER FUNCTION TEST?(BEST ORAL) IHPBA World congress (Seul, Corea del sud)

15-19.5.15 The Concept of Perihilar Cholangiocarcinoma Is Still Valid? Analysis of Clinicopathological Features and Mutational Genes Profiling in a Series of 56 Cases - SSAT-DDW congress (Washington – US)

20-23.4.16 Comparison of UICC/AJCC pN stage, number of metastatic lymph nodes, lymph node ratio and log odds of metastatic lymph node in patients with perihilar cholangiocarcinoma - IHPBA world congress (Sao Paulo, Brasile)



2008 – ad oggi Membership società scientifiche

Societa Italiana di Chirurgia (SIC)

Surgical Society of Alimentary Tract (SSAT)

International Hepato Pancreato Biliary Association (IHPBA)

African-European Hepato-Pancreato-Biliary Association (E-AHPBA)

Italian Chapter International Hepato-Pancreato-Biliary Association (it-IHPBA)

European Neuroendocrine Tumor Society (ENETS)

Associazione Italiana Chirurgia epatica mini-invasiva (IGOMILS)

2009 – ad oggi Premi e riconoscimenti

- SSAT 2006 (Los Angeles – US) poster of distinction “Radiofrequency ablayion for HCC on cirrhosis”

- SSAT 2008 (SanDiego – US) Fellow and resident conference grant “Is liver resection justified in advanced HCC? Results of an observational study on 464 patients”

- Congresso dell’apparato digerente Palazzini 2009 (Roma) -1° premio video “Mesoepatectomia per colangiocarcinoma perilare”

- IHPBA 2012 world congress (Parigi – Francia) Best poster award “Usefulness of contrast-enhanced intraoperative ultrasonography (CE-IOUS) in patients with colorectal liver metastases after preoperative chemotherapy”

- IHPBA 2014 word congress (Seul – Corea del sud) Travel award grant - Best oral presentation “computed tomographic perfusion (CTP) of the liver: a new non-invasive liver function test?”



ATTIVITA’ CLINICA

2016 -- ad oggi Incarico di responsabile del centro regionale specializzato per la chirurgia oncologica epato-biliare

Regione Veneto - Chirurgia generale ed epatobiliare Azienda Ospedaliera Universitaria Integrata di Verona

2015 -- ad oggi Incarico di alta specialità in chirurgia epatobiliare mininvasiva e robotica

Chirurgia generale ed epatobiliare Azienda Ospedaliera Universitaria Integrata di Verona

2000 -- ad oggi Attività operatoria di chirurgia generale con particolare riferimento alla chirurgia digestive oncologica e epatobiliare anche con approccio laparoscopico e robotico

2852 interventi chirurgici eseguiti - 1464 come primo operatore

739 resezione epatiche - 439 come primo eperatore

120 resezioni epatiche miniinvasive come primo operatore-

(110 laparoscopiche – 10 robot assistite)

70 resezioni pancreatiche maggiori – 35 come primo operatore

(59 duodenocefalopancreasectomie – 11 pancreasectomie sinistre o totali)

314 chirurgia digestiva maggiore –106 come primo operatore

2000 – ad oggi Oltre 1000 procedure interventistiche ecoguidate come primo operatore

Oltre 400 procedure di ablazione locali di neoplasie epatobiliari come primo operatore



Lingua Italiano

Altre Lingue COMPRENSIONE PARLATO SCRITTURA

ASCOLTO LETTURA INTERAZIONE ORALE

PRODUZIONE ORALE

INGLESE C1 C1 C1 C1 C1

COMPETENZE INFORMATICHE Utilizzo professionale applicazioni Microsoft Office™ tools, applicative statistici (SPSS inc), Mac OS.



PUBBLICAZIONI SCIENTIFICHE

PUBBLICAZIONI PEER REVIEW INDICIZZATE1. Moruzzi S, Guarini P, Udali S, Ruzzenente A, Guglielmi A, Conci S, Pattini P, Martinelli N, Olivieri O,

Tammen SA, Choi SW, Friso S. One-carbon genetic variants and the role of MTHFD1 1958G>A in liver and colon cancer risk according to global DNA methylation. PLoS One. 2017 Oct 2;12(10):e0185792. doi: 10.1371/journal.pone.0185792. eCollection 2017. PubMed PMID: 28968444.

2. D'Onofrio M, Cardobi N, Ruzzenente A, Conci S, Ciaravino V, Guglielmi A, Mucelli RP. Unenhanced magnetic resonance imaging immediately after adiofrequency ablation of liver malignancy: preliminary results. Abdom Radiol (NY). 2017 Aug 31. doi: 10.1007/s00261-017-1299-9. [Epub ahead of print] PubMed PMID: 28861631.

3. Reames BN, Bagante F, Ejaz A, Spolverato G, Ruzzenente A, Weiss M, Alexandrescu S, Marques HP, Aldrighetti L, Maithel SK, Pulitano C, Bauer TW, Shen F, Poultsides GA, Soubrane O, Martel G, Koerkamp BG, Guglielmi A, Itaru E, Pawlik TM. Impact of adjuvant chemotherapy on survival in patients with intrahepatic cholangiocarcinoma: a multi-institutional analysis. HPB (Oxford). 2017 Oct;19(10):901-909. doi: 10.1016/j.hpb.2017.06.008. Epub 2017 Jul 17. PubMed PMID: 28728891.

4. Ruzzenente A, Conci S, Ciangherotti A, Campagnaro T, Valdegamberi A, Bertuzzo F, Bagante F, Mantovani G, De Angelis M, Dorna AE, Piccino M, Pedrazzani C, Guglielmi A, Iacono C. Impact of age on short-term outcomes of liver surgery: Lessons learned in 10-years' experience in a tertiary referral hepato-pancreato-biliary center. Medicine (Baltimore). 2017 May;96(20):e6955.doi: 0.1097/MD.0000000000006955. PubMed PMID: 28514317; PubMed Central PMCID: PMC5440154.

5. Pedrazzani C, Mantovani G, Fernandes E, Bagante F, Luca Salvagno G, Surci N, Campagnaro T, Ruzzenente A, Danese E, Lippi G, Guglielmi A. Assessment of neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio and platelet count as predictors of long-term outcome after R0 resection for colorectal cancer. Sci Rep. 2017 May 4;7(1):1494. doi: 10.1038/s41598-017-01652-0. PubMed PMID: 28473700; PubMed Central PMCID: PMC5431463.

6. Pedrazzani C, Moro M, Mantovani G, Lazzarini E, Conci S, Ruzzenente A, Lippi G, Guglielmi A. C-reactive protein as early predictor of complications after minimally invasive colorectal resection. J Surg Res. 2017 Apr;210:261-268. doi: 10.1016/j.jss.2016.11.047. Epub 2016 Dec 5. PubMed PMID: 28457337

7. D'Onofrio M, Cingarlini S, Ortolani S, Crosara S, DE Robertis R, Vallerio P, Grego E, Ciaravino V, Ruzzenente A, Landoni L, Scarpa A, Bassi C, Tortora G. Perfusion CT Changes in Liver Metastases from Pancreatic Neuroendocrine Tumors During Everolimus Treatment. Anticancer Res. 2017 Mar;37(3):1305-1311. PubMed PMID: 28314296.

8. Conci S, Ruzzenente A, Sandri M, Bertuzzo F, Campagnaro T, Bagante F, Capelli P, D'Onofrio M, Piccino M, Dorna AE, Pedrazzani C, Iacono C, Guglielmi A. What is the most accurate lymph node staging method for perihilar cholangiocarcinoma? Comparison of UICC/AJCC pN stage, number of metastatic lymph nodes, lymph node ratio, and log odds of metastatic lymph nodes. Eur J Surg Oncol. 2017 Apr;43(4):743-750. doi: 10.1016/j.ejso.2016.12.007. Epub 2017 Jan 8. PubMed PMID: 28094085.

9. Marini O, Costa S, Bevilacqua D, Calzetti F, Tamassia N, Spina C, De Sabata D, Tinazzi E, Lunardi C, Scupoli MT, Cavallini C, Zoratti E, Tinazzi I, Marchetta A, Vassanelli A, Cantini M, Gandini G, Ruzzenente A, Guglielmi A, Missale F, Vermi W, Tecchio C, Cassatella MA, Scapini P. Mature CD10(+) and immature



CD10(-) neutrophils present in G-CSF-treated donors display opposite effects on T cells. Blood. 2017 Mar 9;129(10):1343-1356. doi: 10.1182/blood-2016-04-713206. Epub 2017 Jan 4. Erratum in: Blood. 2017 Jun 15;129(24):3271. PubMed PMID: 28053192.

10. Pedrazzani C, Mantovani G, Salvagno GL, Baldiotti E, Ruzzenente A, Iacono C, Lippi G, Guglielmi A. Elevated fibrinogen plasma level is not an independent predictor of poor prognosis in a large cohort of Western patients undergoing surgery for colorectal cancer. World J Gastroenterol. 2016 Dec 7;22(45):9994-10001. doi: 10.3748/wjg.v22.i45.9994. PubMed PMID: 28018106; PubMed Central PMCID: PMC5143766.

11. Moruzzi S, Udali S, Ruzzenente A, Guglielmi A, Guarini P, Martinelli N, Conci S, Mazzi F, Pattini P, Tammen SA, Olivieri O, Pizzolo F, Choi SW, Friso S. The RFC1 80G>A, among Common One-Carbon Polymorphisms, Relates to Survival Rate According to DNA Global Methylation in Primary Liver Cancers. PLoS One. 2016 Dec 9;11(12):e0167534. doi: 10.1371/journal.pone.0167534. eCollection 2016. PubMed PMID: 27936032; PubMed Central PMCID: PMC5147923.

12. Cingarlini S, Ortolani S, Salgarello M, Butturini G, Malpaga A, Malfatti V, DʼOnofrio M, Davì MV, Vallerio P, Ruzzenente A, Capelli P, Citton E, Grego E, Trentin C, De Robertis R, Scarpa A, Bassi C, Tortora G. Role of Combined 68Ga-DOTATOC and 18F-FDG Positron Emission Tomography/Computed Tomography in the Diagnostic Workup of Pancreas Neuroendocrine Tumors: Implications for Managing Surgical Decisions. Pancreas. 2017 Jan;46(1):42-47. PubMed PMID: 27906872.

13. Sasaki K, Morioka D, Conci S, Margonis GA, Sawada Y, Ruzzenente A, Kumamoto T, Iacono C, Andreatos N, Guglielmi A, Endo I, Pawlik TM. The Tumor Burden Score: A New "Metro-ticket" Prognostic Tool For Colorectal Liver Metastases Based on Tumor Size and Number of Tumors. Ann Surg. 2016 Oct 19. [Epub ahead of print] PubMed PMID: 27763897.

14. Ruzzenente A, Bagante F, Bertuzzo F, Aldrighetti L, Ercolani G, Giuliante F, Ferrero A, Torzilli G, Grazi GL, Ratti F, Cucchetti A, De Rose AM, Russolillo N, Cimino M, Perri P, Cataldo I, Scarpa A, Guglielmi A, Iacono C. A Novel Nomogram to Predict the Prognosis of Patients Undergoing Liver Resection for Neuroendocrine Liver Metastasis: an Analysis of the Italian Neuroendocrine Liver Metastasis Database.J Gastrointest Surg. 2016 Aug 8. IF 2,8

15. Ruzzenente A, Bagante F, Sandri BSM, Pedrazzani C, Brunelli M, et al. (2016) Risk A Novel Prognostic Score based on Serum Alpha-Fetoprotein, Number of Nodules, and MYC Gene Status Predicts Prognosis of Patients after Liver Resection for Hepatocellular Carcinoma. J Integr Oncol 5: 168. doi:10.4172/2329- 6771.1000168

16. Bagante F, Spolverato G, Ruzzenente A, Wilson A, Gani F, Conci S, Yahanda A, Campagnaro T, Guglielmi A, Pawlik TM. Validation of a Nomogram to Predict the Risk of Perioperative Blood Transfusion for Liver Resection. World J Surg. 2016 May 11. IF 2,5

17. Bagante F, Tran T, Spolverato G, Ruzzenente A, Buttner S, Ethun CG, Groot Koerkamp B, Conci S, Idrees K, Isom CA, Fields RC, Krasnick B, Weber SM, Salem A, Martin RC, Scoggins C, Shen P, Mogal HD, Schmidt C, Beal E, Hatzaras I, Vitiello G, et al. Perihilar Cholangiocarcinoma: Number of Nodes Examined and Optimal Lymph Node Prognostic Scheme. J Am Coll Surg. 2016 May;222(5):750-759.e2. IF 4,2

18. Conci S, De Bellis M, Ruzzenente A, Capelli P, D'Onofrio M, Iacono C, Guglielmi A. Totally intrabiliary colorectal liver metastasis mimicking intraductal growth-type cholangiocarcinoma. Updates Surg. 2016 Jun;68(2):211-2. doi: 10.1007/s13304-016-0364-1.

19. Bagante F, Spolverato G, Cucchetti A, Gani F, Popescu I, Ruzzenente A, Marques HP, Aldrighetti L,



Gamblin TC, Maithel SK, Sandroussi C, Bauer TW, Shen F, Poultsides GA, Marsh JW, Guglielmi A, Pawlik TM. Defining when to offer operative treatment for intrahepatic cholangiocarcinoma: A regret-based decision curves analysis. Surgery. 2016 Jul;160(1):106-17. doi: 10.1016/j.surg.2016.01.023. Epub 2016 Apr 1. IF 3,3

20. Bailey P, Chang DK, Nones K, Johns AL, Patch AM, Gingras MC, Miller DK, Christ AN, Bruxner TJ, Quinn MC, Nourse C, Murtaugh LC, Harliwong I, Idrisoglu S, Manning S, Nourbakhsh E, Wani S, Fink L, Holmes O, Chin V, Anderson MJ, Kazakoff S, et al. (Ruzzenente A Collaborators) Genomic analyses identify molecular subtypes of pancreatic cancer. Nature. 2016 Mar 3;531(7592):47-52. doi: 10.1038/nature16965. Epub 2016 Feb 24. IF 38,1

21. Andrici J, Goeppert B, Sioson L, Clarkson A, Renner M, Stenzinger A, Tayao M, Watson N, Farzin M, Toon CW, Smith RC, Mittal A, Samra JS, Hugh TJ, Chou A, Lawlor RT, Weichert W, Schirmacher P, Sperandio N, Ruzzenente A, Scarpa A, Gill AJ. Loss of BAP1 Expression Occurs Frequently in Intrahepatic Cholangiocarcinoma. Medicine (Baltimore). 2016 Jan;95(2):e2491. doi: 10.1097/MD.0000000000002491. IF1,2

22. Iacono C, Zicari M, Conci S, Valdegamberi A, De Angelis M, Pedrazzani C, Ruzzenente A, Guglielmi A. Management of pancreatic trauma: A pancreatic surgeon's point of view. Pancreatology. 2016 May-Jun;16(3):302-8. doi: 10.1016/j.pan.2015.12.004. IF 2,4

23. Ruzzenente A, Fassan M, Conci S, Simbolo M, Lawlor RT, Pedrazzani C, Capelli P, D'Onofrio M, Iacono C, Scarpa A, Guglielmi A. Cholangiocarcinoma Heterogeneity Revealed by Multigene Mutational Profiling: Clinical and Prognostic Relevance in Surgically Resected Patients. Ann Surg Oncol. 2016 May;23(5):1699-707. doi: 10.1245/s10434-015-5046-6. Epub 2015 Dec 30. IF 3,6

24. Simbolo M, Fassan M, Mafficini A, Lawlor RT, Ruzzenente A, Scarpa A. New genomic landscapes and therapeutic targets for biliary tract cancers. Front Biosci (Landmark Ed). 2016 Jan 1;21:707-18. IF 2,48

25. Udali S, Moruzzi S, Ruzzenente A, Choi SW, Friso S. Reply. Hepatology. 2016 May;63(5):1746-7. doi: 10.1002/hep.28271. Epub 2015 Nov 26. IF 11,7

26. Ruzzenente A, Conci S, Valdegamberi A, Pedrazzani C, Guglielmi A. Role of surgery in the treatment of intrahepatic cholangiocarcinoma. Eur Rev Med Pharmacol Sci. 2015 Aug;19(15):2892-900. IF 1,5

27. Ercolani G, Dazzi A, Giovinazzo F, Ruzzenente A, Bassi C, Guglielmi A, Scarpa A, D'Errico A, Pinna AD. Intrahepatic, peri-hilar and distal cholangiocarcinoma: Three different locations of the same tumor or three different tumors? Eur J Surg Oncol. 2015 Sep;41(9):1162-9. doi: 10.1016/j.ejso.2015.05.013. Epub 2015 Jun 10. IF 2,9

28. De Robertis R, Tinazzi Martini P, Demozzi E, Puntel G, Ortolani S, Cingarlini S, Ruzzenente A, Guglielmi A, Tortora G, Bassi C, Pederzoli P, D'Onofrio M. Prognostication and response assessment in liver and pancreatic tumors: The new imaging. World J Gastroenterol. 2015 Jun 14;21(22):6794-808. doi: 10.3748/wjg.v21.i22.6794. Review. IF 2,78

29. Udali S, Guarini P, Ruzzenente A, Ferrarini A, Guglielmi A, Lotto V, Tononi P, Pattini P, Moruzzi S, Campagnaro T, Conci S, Olivieri O, Corrocher R, Delledonne M, Choi SW, Friso S. DNA methylation and gene expression profiles show novel regulatory pathways in hepatocellular carcinoma. Clin Epigenetics. 2015;7:43. doi: 10.1186/s13148-015-0077-1. IF:4,32

30. Udali S, Guarini P, Moruzzi S, Ruzzenente A, Tammen SA, Guglielmi A, Conci S, Pattini P, Olivieri O, Corrocher R, Choi SW, Friso S. Global DNA methylation and hydroxymethylation differ in hepatocellular carcinoma and cholangiocarcinoma and relate to survival rate. Hepatology. 2015 Aug;62(2):496-504. doi: 10.1002/hep.27823. Epub 2015 Apr 28. IF:11,7

31. Pedrazzani C, Lauka L, Sforza S, Ruzzenente A, Nifosì F, Delaini G, Guglielmi A. Management of nodal



disease from colon cancer in the laparoscopic era. Int J Colorectal Dis. 2015 Mar;30(3):303-14. doi: 10.1007/s00384-014-2075-8. Epub 2014 Nov 22. Review. IF: 2,3

32. Iacono C, Ruzzenente A, Bortolasi L, Guglielmi A. Central pancreatectomy: the Dagradi Serio Iacono operation. Evolution of a surgical technique from the pioneers to the robotic approach.World J Gastroenterol. 2014 Nov 14;20(42):15674-81. doi: 10.3748/wjg.v20.i42.15674. Review. IF 2,78

33. Iacono C, Ruzzenente A, Conci S, Xillo L, Guglielmi A. Head dorsal pancreatectomy: an alternative to the pancreaticoduodenectomy for not enucleable benign or low-grade malignant lesions. Pancreatology. 2014 Sep-Oct;14(5):419-24. doi: 10.1016/j.pan.2014.07.014. Epub 2014 Aug 8. IF 2,4

34. Danese E, Ruzzenente O, Ruzzenente A, Iacono C, Bertuzzo F, Gelati M, Conci S, Bendinelli S, Bonizzato G, Guglielmi A, Salvagno GL, Lippi G, Guidi GC. Assessment of bile and serum mucin5AC in cholangiocarcinoma: diagnostic performance and biologic significance. Surgery. 2014 Nov;156(5):1218-24. doi: 10.1016/j.surg.2014.05.006. Epub 2014 Aug 21. IF 3,3

35. Guglielmi A, Ruzzenente A, Conci S, Valdegamberi A, Vitali M, Bertuzzo F, De Angelis M, Mantovani G, Iacono C. Hepatocellular carcinoma: surgical perspectives beyond the barcelona clinic liver cancer recommendations. World J Gastroenterol. 2014 Jun 28;20(24):7525-33. doi: 10.3748/wjg.v20.i24.7525. Review. IF 2,78

36. Pedrazzani C, Moro M, Ghezzi G, Ruzzenente A, Delaini G, Guglielmi A. What should we intend for minimally invasive treatment of colorectal cancer? Surg Oncol. 2014 Sep;23(3):147-54. doi: 10.1016/j.suronc.2014.06.002. Epub 2014 Jun 11. Review. IF 3,5

37. Simbolo M, Fassan M, Ruzzenente A, Mafficini A, Wood LD, Corbo V, Melisi D, Malleo G, Vicentini C, Malpeli G, Antonello D, Sperandio N, Capelli P, Tomezzoli A, Iacono C, Lawlor RT, Bassi C, Hruban RH, Guglielmi A, Tortora G, de Braud F, Scarpa A. Multigene mutational profiling of cholangiocarcinomas identifies actionable molecular subgroups. Oncotarget. 2014 May 15;5(9):2839-52. IF 5,0

38. D'Onofrio M, De Robertis R, Ruzzenente A, Mantovani W, Puntel G, Crosara S, Canestrini S, Guglielmi A, Mucelli RP. Time-to-peak values can estimate hepatic functional reserve in patients undergoing surgical resection: a comparison between perfusion CT and indocyanine green retention test. J Comput Assist Tomogr. 2014 Sep-Oct;38(5):733-41. doi: 10.1097/RCT.0000000000000102. IF 1,4

39. Guglielmi A, Ruzzenente A, Bertuzzo F, Iacono C. Assessment of nodal status for perihilar cholangiocarcinoma location, number, or ratio of involved nodes. Hepatobiliary Surg Nutr. 2013 Oct;2(5):281-3. doi: 10.3978/j.issn.2304-3881.2013.08.10.

40. Luchini C, Capelli P, Fassan M, Simbolo M, Mafficini A, Pedica F, Ruzzenente A, Guglielmi A, Corbo V, Scarpa A. Next-generation histopathologic diagnosis: a lesson from a hepatic carcinosarcoma. J Clin Oncol. 2014 Jun 10;32(17):e63-6. doi: 10.1200/JCO.2012.47.5855. Epub 2014 Feb 3. No abstract available. IF 20,9

41. Ruzzenente A, Iacono C, Conci S, Bertuzzo F, Salvagno G, Ruzzenente O, Campagnaro T, Valdegamberi A, Pachera S, Bagante F, Guglielmi A. A novel serum marker for biliary tract cancer: diagnostic and prognostic values of quantitative evaluation of serum mucin 5AC (MUC5AC). Surgery. 2014 Apr;155(4):633-9. doi: 10.1016/j.surg.2013.12.003. Epub 2013 Dec 14. IF 3,3

42. Guglielmi A, Ruzzenente A, Valdegamberi A, Bagante F, Conci S, Pinna AD, Ercolani G, Giuliante F, Capussotti L, Aldrighetti L, Iacono C. Hepatolithiasis-associated cholangiocarcinoma: results from a multi-institutional national database on a case series of 23 patients. Eur J Surg Oncol. 2014 May;40(5):567-75. doi: 10.1016/j.ejso.2013.12.006. Epub 2013 Dec 18. IF 2,9

43. Jiao Y, Pawlik TM, Anders RA, Selaru FM, Streppel MM, Lucas DJ, Niknafs N, Guthrie VB, Maitra A, Argani P, Offerhaus GJ, Roa JC, Roberts LR, Gores GJ, Popescu I, Alexandrescu ST, Dima S, Fassan M,



Simbolo M, Mafficini A, Capelli P, Lawlor RT, Ruzzenente A, et al. Exome sequencing identifies frequent inactivating mutations in BAP1, ARID1A and PBRM1 in intrahepatic cholangiocarcinomas. Nat Genet. 2013 Dec;45(12):1470-3. doi: 10.1038/ng.2813. Epub 2013 Nov 3. IF 31,6

44. Guglielmi A, Ruzzenente A, Campagnaro T, Valdegamberi A, Bagante F, Bertuzzo F, Conci S, Iacono C. Patterns and prognostic significance of lymph node dissection for surgical treatment of perihilar and intrahepatic cholangiocarcinoma. J Gastrointest Surg. 2013 Nov;17(11):1917-28. doi: 10.1007/s11605-013-2331-1. Epub 2013 Sep 19. IF 2,8

45. Pedica F, Ruzzenente A, Bagante F, Capelli P, Cataldo I, Pedron S, Iacono C, Chilosi M, Scarpa A, Brunelli M, Tomezzoli A, Martignoni G, Guglielmi A. A re-emerging marker for prognosis in hepatocellular carcinoma: the add-value of fishing c-myc gene for early relapse. PLoS One. 2013 Jul 10;8(7):e68203. doi: 10.1371/journal.pone.0068203. Print 2013. IF 3,05

46. Iacono C, Verlato G, Ruzzenente A, Campagnaro T, Bacchelli C, Valdegamberi A, Bortolasi L, Guglielmi A.Systematic review of central pancreatectomy and meta-analysis of central versus distal pancreatectomy.Br J Surg. 2013 Jun;100(7):873-85. doi: 10.1002/bjs.9136. Review. IF 5,5

47. Ruzzenente A, Conci S, Iacono C, Valdegamberi A, Campagnaro T, Bertuzzo F, Bagante F, De Angelis M, Guglielmi A. Usefulness of contrast-enhanced intraoperative ultrasonography (CE-IOUS) in patients with colorectal liver metastases after preoperative chemotherapy. J Gastrointest Surg. 2013 Feb;17(2):281-7. doi: 10.1007/s11605-012-2043-y. Epub 2012 Oct 11. IF 2,8

48. Iacono C, Ruzzenente A, Campagnaro T, Bortolasi L, Valdegamberi A, Guglielmi A. Role of preoperative biliary drainage in jaundiced patients who are candidates for pancreatoduodenectomy or hepatic resection: highlights and drawbacks. Ann Surg. 2013 Feb;257(2):191-204. doi: 10.1097/SLA.0b013e31826f4b0e. Review. IF 8,56

49. Giuliante F, Ardito F, Pinna AD, Sarno G, Giulini SM, Ercolani G, Portolani N, Torzilli G, Donadon M, Aldrighetti L, PulitanÃ² C, Guglielmi A, Ruzzenente A, Capussotti L, Ferrero A, Calise F, Scuderi V, Federico B, Nuzzo G. bLiver resection for hepatocellular carcinoma <3 cm: results of an Italian multicenter study on 588 patients. J Am Coll Surg. 2012 Aug;215(2):244-54. doi: 10.1016/j.jamcollsurg.2012.04.013. Epub 2012 May 26. IF 4,2

50. Guglielmi A, Ruzzenente A, Conci S, Valdegamberi A, Iacono C. How much remnant is enough in liver resection? Dig Surg. 2012;29(1):6-17. doi: 10.1159/000335713. Epub 2012 Mar 15. Review. IF 1,7

51. Nuzzo G, Giuliante F, Ardito F, Giovannini I, Aldrighetti L, Belli G, Bresadola F, Calise F, Dalla Valle R, D'Amico DF, Gennari L, Giulini SM, Guglielmi A, Jovine E, Pellicci R, Pernthaler H, Pinna AD, Puleo S, Torzilli G, Capussotti L; Italian Chapter of the International Hepato-Pancreato-Biliary Association, Cillo U, Ruzzenente A et al. Improvement in perioperative and long-term outcome after surgical treatment of hilar cholangiocarcinoma: results of an Italian multicenter analysis of 440 patients. Arch Surg. 2012 Jan;147(1):26-34. doi: 10.1001/archsurg.2011.771. IF 4,1

52. Ruzzenente A, Valdegamberi A, Campagnaro T, Conci S, Pachera S, Iacono C, Guglielmi A. Hepatocellular carcinoma in cirrhotic patients with portal hypertension: is liver resection always contraindicated? World J Gastroenterol. 2011 Dec 14;17(46):5083-8. doi: 10.3748/wjg.v17.i46.5083. IF 2,78

53. Ruzzenente A, Guglielmi A, Sandri M, Campagnaro T, Valdegamberi A, Conci S, Bagante F, Turcato G, D'Onofrio M, Iacono C. Surgical resection versus local ablation for HCC on cirrhosis: results from a propensity case-matched study. J Gastrointest Surg. 2012 Feb;16(2):301-11; discussion 311. doi: 10.1007/s11605-011-1745-x. Epub 2011 Nov 18. IF 2,8

54. Guglielmi A, Ruzzenente A, Campagnaro T, Pachera S, Conci S, Valdegamberi A, Sandri M, Iacono C. Prognostic significance of lymph node ratio after resection of peri-hilar cholangiocarcinoma. HPB (Oxford).



2011 Apr;13(4):240-5. doi: 10.1111/j.1477-2574.2010.00277.x. Epub 2011 Jan 28. IF 2,9

55. Guglielmi A, Ruzzenente A, Campagnaro T, Pachera S, Valdegamberi A, Capelli P, Pedica F, Nicoli P, Conci S, Iacono C. Does intrahepatic cholangiocarcinoma have better prognosis compared to perihilar cholangiocarcinoma? J Surg Oncol. 2010 Feb 1;101(2):111-5. doi: 10.1002/jso.21452. IF 3,1

56. D'Onofrio M, Gallotti A, Martone E, Nicoli L, Mautone S, Ruzzenente A, Mucelli RP. Is intraoperative ultrasound (IOUS) still useful for the detection of liver metastases? J Ultrasound. 2009 Dec;12(4):144-7. doi: 10.1016/j.jus.2009.09.003. Epub 2009 Sep 25. IF 1,5

57. Gallotti A, D'Onofrio M, Ruzzenente A, Martone E, De Robertis R, Guglielmi A, Pozzi Mucelli R. Contrast-enhanced ultrasonography (CEUS) immediately after percutaneous ablation of hepatocellular carcinoma. Radiol Med. 2009 Oct;114(7):1094-105. doi: 10.1007/s11547-009-0436-0. Epub 2009 Sep 5. IF 1,5

58. Vecchiato F, D'Onofrio M, MalagÃ² R, Martone E, Gallotti A, Faccioli N, Cantisani V, Marigliano C, Ruzzenente A, Pozzi Mucelli R. Detection of focal liver lesions: from the subjectivity of conventional ultrasound to the objectivity of volume ultrasound. Radiol Med. 2009 Aug;114(5):792-801. doi: 10.1007/s11547-009-0421-7. Epub 2009 Jun 23. English, Italian. IF 1,5

59. Ruzzenente A, Capra F, Pachera S, Iacono C, Piccirillo G, Lunardi M, Pistoso S, Valdegamberi A, D'Onofrio M, Guglielmi A. Is liver resection justified in advanced hepatocellular carcinoma? Results of an observational study in 464 patients. J Gastrointest Surg. 2009 Jul;13(7):1313-20. doi: 10.1007/s11605-009-0903-x. Epub 2009 May 6. IF 2,8

60. Guglielmi A, Ruzzenente A, Campagnaro T, Pachera S, Valdegamberi A, Nicoli P, Cappellani A, Malfermoni G, Iacono C. Intrahepatic cholangiocarcinoma: prognostic factors after surgical resection. World J Surg. 2009 Jun;33(6):1247-54. doi: 10.1007/s00268-009-9970-0. IF 2,5

61. Guglielmi A, Ruzzenente A, Valdegamberi A, Pachera S, Campagnaro T, D'Onofrio M, Martone E, Nicoli P, Iacono C. Radiofrequency ablation versus surgical resection for the treatment of hepatocellular carcinoma in cirrhosis. J Gastrointest Surg. 2008 Jan;12(1):192-8. Epub 2007 Nov 13. IF 2,8

62. Guglielmi A, Ruzzenente A, Pachera S, Valdegamberi A, Sandri M, D'Onofrio M, Iacono C. Comparison of seven staging systems in cirrhotic patients with hepatocellular carcinoma in a cohort of patients who underwent radiofrequency ablation with complete response. Am J Gastroenterol. 2008 Mar;103(3):597-604. Epub 2007 Oct 26. IF 10,3

63. Iacono C, Bortolasi L, Facci E, Nifosì F, Pachera S, Ruzzenente A, Guglielmi A. The Dagradi-Serio-Iacono operation central pancreatectomy. J Gastrointest Surg. 2007 Mar;11(3):364-76. IF 2,8

64. Guglielmi A, Ruzzenente A, Sandri M, Pachera S, Pedrazzani C, Tasselli S, Iacono C. Radio frequency ablation for hepatocellular carcinoma in cirrhotic patients: prognostic factors for survival. J Gastrointest Surg. 2007 Feb;11(2):143-9. IF 2,8

65. Pedrazzani C, Veraldi GF, Tasselli S, Tomasi I, Bernini M, Giacopuzzi S, Ruzzenente A, Guglielmi A, de Manzoni G. Surgical treatment of gastric cancer with coexistent abdominal aortic aneurysm. Personal experience and literature review. Hepatogastroenterology. 2006 Nov-Dec;53(72):973-5. Review. IF 0,79

66. Veraldi GF, De Manzoni G, Tasselli S, Minicozzi A, Ruzzenente A, Pacca R, Firpo M.Iatrogenic axillary artery injury from humeral neck fracture repair. A rare and unusual event in which and aggressive strategy was mandatory to save a child limb. Chir Ital. 2006 Mar-Apr;58(2):247-51. Review.

67. Borzellino G, Ruzzenente A, Minicozzi AM, Giovinazzo F, Pedrazzani C, Guglielmi A. Laparoscopic hepatic resection. Surg Endosc. 2006 May;20(5):787-90. Epub 2006 Mar 16. IF 3,5

68. Veraldi GF, Tasselli S, Firpo M, Pedrazzani C, Ruzzenente A. US-guided percutaneous management of femoral artery pseudoaneurysms by thrombin injection: personal experience and review of the literature.



Chir Ital. 2005 Nov-Dec;57(6):723-30. Review. Italian.

69. Donataccio M, Ruzzenente A, Pachera S, Genco B, Donataccio D. Caval anastomosis in liver transplantation: prospective experience of Verona liver transplantation program. Transplant Proc. 2005 Jul-Aug;37(6):2605-6. IF 0,86

70. de Manzoni G, Pedrazzani C, Laterza E, Pasini F, Grandinetti A, Bernini M, Ruzzenente A, Zerman G, Tomezzoli A, Cordiano C. Induction chemoradiotherapy for squamous cell carcinoma of the thoracic esophagus: impact of increased dosage on long-term results. Ann Thorac Surg. 2005 Oct;80(4):1176-83. IF 2,9

71. Pedrazzani C, Laterza E, Pasini F, Grandinetti A, Bernini M, Giacopuzzi S, Zerman G, Tasselli S, Ruzzenente A, De Manzoni G. Long-term results of neoadjuvant radiochemotherapy in squamous carcinoma of the thoracic esophagus. Minerva Chir. 2005 Feb;60(1):11-6. Italian.

72. Pedrazzani C, Pasini F, Giacopuzzi S, Bernini M, Gabbani M, Grandinetti A, Tomezzoli A, Ruzzenente A, Guglielmi A, de Manzoni G.Preliminary results of neoadjuvant treatment of adenocarcinoma of the gastro-esophageal junction.Chir Ital. 2005 Jan-Feb;57(1):9-14. Italian.

73. Guglielmi A, Fior F, Halmos O, Veraldi GF, Rossaro L, Ruzzenente A, Cordiano C. Transhepatic fibrinolysis of mesenteric and portal vein thrombosis in a patient with ulcerative colitis: a case report. World J Gastroenterol. 2005 Apr 7;11(13):2035-8. Review. IF 2,78

74. Pedrazzani C, Catalano F, Festini M, Zerman G, Tomezzoli A, Ruzzenente A, Guglielmi A, de Manzoni G. Endoscopic ablation of Barrett's esophagus using high power setting argon plasma coagulation: a prospective study. World J Gastroenterol. 2005 Mar 28;11(12):1872-5. IF 2,78

75. Pedrazzani C, Pasini F, Giacopuzzi S, Bernini M, Ruzzenente A, Festini M, Tomasi I, Cristadoro L, de Manzoni G. Surgical treatment of gasto-esophageal junction adenocarcinoma: long-term results of a single Italian centre. G Chir. 2004 Oct;25(10):325-33. Italian.

76. Vivarelli M, Guglielmi A, Ruzzenente A, Cucchetti A, Bellusci R, Cordiano C, Cavallari A. Surgical resection versus percutaneous radiofrequency ablation in the treatment of hepatocellular carcinoma on cirrhotic liver. Ann Surg. 2004 Jul;240(1):102-7. IF 8,56

77. Ruzzenente A, Manzoni GD, Molfetta M, Pachera S, Genco B, Donataccio M, Guglielmi A. Rapid progression of hepatocellular carcinoma after Radiofrequency Ablation. World J Gastroenterol. 2004 Apr 15;10(8):1137-40. IF 2,78

78. Guglielmi A, Ruzzenente A, Battocchia A, Tonon A, Fracastoro G, Cordiano C. Radiofrequency ablation of hepatocellular carcinoma in cirrhotic patients. Hepatogastroenterology. 2003 Mar-Apr;50(50):480-4. IF 0,78

79. de Manzoni G, Catalano F, Festini M, Guglielmi A, Lombardo F, Kind R, Rodella L, Ruzzenente A, Zerman G. Acute hemorrhage caused by duodenal ulcer. Results of endoscopic treatment of the first bleeding episode and of recurrences]. Ann Ital Chir. 2002 Jul-Aug;73(4):387-94; discussion 394-6. Italian.

80. Guglielmi A, Ruzzenente A, Sandri M, Kind R, Lombardo F, Rodella L, Catalano F, de Manzoni G, Cordiano C. Risk assessment and prediction of rebleeding in bleeding gastroduodenal ulcer. Endoscopy. 2002 Oct;34(10):778-86. IF 5,6

81. de Manzoni G, Catalano F, Festini M, Lombardo F, Kind R, Rodella L, Ruzzenente A, Zerman G, Valloncini E. [Esophageal non-variceal hemorrhage: a clinical and epidemiological study]. G Chir. 2002 May;23(5):199-204. Italian.

82. De Manzoni G, Catalano F, Festini M, Lombardo F, Kind R, Pachera S, Rodella L, Ruzzenente A, Valloncini E, Zerman G. [Peptic ulcer hemorrhage in the elderly]. Minerva Med. 2002 Jun;93(3):211-7.



Italian.

83. de Manzoni G, Ruzzenente A, Pachera S, Festini M, Zerman G, Guglielmi A, Catalano F, Rodella L. Acute hemorrhage secondary to gastric ulcer. Results of emergency endoscopic treatment in 775 cases. Chir Ital. 2001 Nov-Dec;53(6):783-91. Italian.

84. Kind R, Guglielmi A, Rodella L, Lombardo F, Catalano F, Ruzzenente A, Borzellino G, Girlanda R, Leopardi F, Pratticò F, Cordiano C. Bucrylate treatment of bleeding gastric varices: 12 years' experience. Endoscopy. 2000 Jul;32(7):512-9. IF 5,6

MONOGRAFIE

1. D'Onofrio M, Ruzzenente A (2007). Ecografie e procedure intervenistiche percutanee: fegato, vie biliari e pancreas . MILANO:Springer-Verlag Italia, ISBN: 8847010616

2. Guglielmi A, Ruzzenente A, Iacono C (2008). Surgical Treatment of Hilar and Intrahepatic Cholangiocarcinoma. Springer Verlag Milan

CONTRIBUTO IN LIBRI SCIENTIFICI

1. Andrea Ruzzenente, Alessandro Valdegamberi, Simone Conci and Alfredo Guglielmi (2016). Treatment Approach of HCC. Hepatocellular Carcinoma in the 3rd Millennium.

2. Valdegamberi A, Ruzzenente A, S. Conci, F. Bagante, A. Cappellani and A. Guglielmi (2015), Primary Liver Cancer: Prognostic Factors and Predictive Response to Therapy. Prognostic and Predictive Response Therapy Factors in Cancer Disease (Colorectal, Breast, Liver, Lung, Gastric, Renal and Prostate Cancers)

3. Valdegamberi A., Ruzzenente A., Guglielmi A. (2011). INVECCHIAMENTO E CHIRURGIA. In: Manuale di gerontologia e geriatria. p. 595-599

4. Valdegamberi A., Ruzzenente A., Guglielmi a (2011). URGENZE CHIRURGICHE ADDOMINALI. In: Manuale di gerontologia e geriatria. p. 603-610

5. Ruzzenente A, Zugni C, Guglielmi A (2008). Clinical Pictures of Intrahepatic Lithiasis. In: Biliary Lithiasis. p. 455-465, MILANO:Springer-Verlag Italia, ISBN: 978-88-470-0762-8

6. D'Onofrio M, Ruzzenente A, Martone E, Manfrin E, Malagò R, Casarin A, Pozzi Mucelli R (2008). Procedure diagnostiche (Fegato e vie biliari). In: (a cura di): D'Onofrio Mirko Ruzzenente Andrea, Ecografia e procedure interventistche percutanee: fegato, vie biliari, e pancreas. p. 3-24, Springer-Verlag Italia, ISBN: 9788847010611

7. Ruzzenente A, D'Onofrio M, Pachera S, Martone E (2008). Procedure terapeutiche (Fegato e vie biliari). In: (a cura di): D'Onofrio Mirko Ruzzenente Andrea, Ecografia e procedure interventistche percutanee: fegato, vie biliari, e pancreas. p. 25-50, Springer-Verlag Italia, ISBN: 9788847010611

8. Pezzangora V, Ruzzenente A (2005). Analisi sull’adozione di un modello organizzativo ispirato all’Ospedale Feriale,. In: Manuale di Day Sugery . PADOVA:PICCIN, ISBN: 978-88-299-1724-2

9. Guglielmi A, Pachera S, Ruzzenente A. (2005). Surgical therapy of hepatic metastases. In: “Rectal Cancer”. New frontiers in diagnosis and treatment. Springer-Verlag Italia



10. Guglielmi A, Ruzzenente A, de Manzoni G, Cordiano C (2003). I tumori maligni del pancreas esocrino. In: Trattato di Clinica e terapia Chirurgica.

11. Guglielmi A, Ruzzenente A. (2003). I tumori secondari del fegato.. In: Trattato di chirurgia oncologica.

12. Guglielmi A., Ruzzenente A, Molfetta M, Pachera S, Cordiano C(2003). IL TRAPIANTO DI FEGATO. In: Condividere la vita. Cortina edizioni

ABSTRACT SU RIVISTA

1. Ruzzenente, A; De Angelis, M; Conci, S; Bagante, F; Valdegamberi, A; Bertuzzo, F; Mantovani, G; Iacono, C; Guglielmi, A; ,Surgical outcomes of metabolic syndrome related HCC: A comparative study with viral and alcoholic HCC,HPB,18,,e730-e731,2016,Elsevier

2. Conci, S; Ruzzenente, A; Valdegamberi, A; Fontana, M; Bertuzzo, F; Piccino, M; Mantovani, G; Iacono, C; Guglielmi, A; ,Treatment of recurrent hcc after curative resection improves survival,HPB,18,,e731-e732,2016,Elsevier

3. Conci, S; Ruzzenente, A; Bertuzzo, F; Campagnaro, T; Dorna, A; De Angelis, M; Piccino, M; Guglielmi, A; ,"Comparison of UICC/AJCC pN stage, number of metastatic lymph nodes, lymph node ratio and log odds of metastatic lymph node in patients with perihilar cholangiocarcinoma", HPB,18, ,e24,2016, Elsevier

4. Ruzzenente, A; Conci, S; Ciangherotti, A; Bertuzzo, F; Dorna, A; Michela, DA; Bagante, F; Piccino, M; Iacono, C; Guglielmi, A; How can we identify elderly patients at low risk for liver resection?,HPB,18,,e148-e149,2016,Elsevier

5. Moruzzi, Sara; Udali, Silvia; Guarini, Patrizia; Guglielmi, Alfredo; Ruzzenente, Andrea; Pattini, Patrizia; Conci, Simone; Tammen, Stephanie; Olivieri, Oliviero; Choi, Sang-Woon; ,The RFC1 80G> A Relates to Survival Rate According to PBMCs DNA Global Methylation in Primary Liver Cancer,The FASEB Journal,29,1 Supplement,749.4,2015,Federation of American Societies for Experimental Biology

6. Guarini, Patrizia; Moruzzi, Sara; Udali, Silvia; Guglielmi, Alfredo; Ruzzenente, Andrea; Pattini, Patrizia; Martinelli, Nicola; Olivieri, Oliviero; Choi, Sang-Woon; Friso, Simonetta; ,The MTHFD1 1958G> A Relates to Survival Rate According to PBMCs DNA Global Methylation in Cancer,The FASEB Journal,29,1 Supplement,749.3,2015,Federation of American Societies for Experimental Biology

7. Udali, Silvia; Guarini, Patrizia; Moruzzi, Sara; Ruzzenente, Andrea; Tammen, Stephanie; Guglielmi, Alfredo; Conci, Simone; Pattini, Patrizia; Choi, Sang-Woon; Friso, Simonetta; ,Global DNA Methylation and Hydroxymethylation Differ in Hepatocellular-and Cholangio-Carcinoma and Relate to Survival Rate,The FASEB Journal,29,1 Supplement,918.10,2015,Federation of American Societies for Experimental Biology

8. Ruzzenente, Andrea; De Angelis, Michela; Conci, Simone; Bagante, Fabio; Valdegamberi, Alessandro; Bertuzzo, Francesca; Iacono, Calogero; Guglielmi, Alfredo; Outcome of Liver Resection for Metabolic Syndrome Related HCC: A Comparative Study With Viral and Alcohol Related HCC,Gastroenterology,148,4,S-1114,2015,Elsevier

9. Ruzzenente, Andrea; Simbolo, Michele; Conci, Simone; Fassan, Matteo; Lawlor, Rita Teresa; Pedrazzani, Corrado; Capelli, Paola; Iacono, Calogero; Scarpa, Aldo; Guglielmi, Alfredo; ,483 The Concept of Perihilar Cholangiocarcinoma Is Still Valid? Analysis of Clinicopathological



Features and Mutational Genes Profiling in a Series of 56 Cases,Gastroenterology,148,4,S-1111,2015,Elsevier

10. Ortolani, S; De Robertis, R; D'Onofrio, M; Cingarlini, S; Crosara, S; Butturini, G; Ruzzenente, A; Davi, M; Vallerio, P; Trentin, C; ,Perfusion Changes in Liver Metastases (LM) from Pancreatic Neuroendocrine Tumors (PanNETs) during Everolimus (E) Treatment: Update of Perfusion CT (P-CT) Study,NEUROENDOCRINOLOGY,102,1-2,113-113,2015,"KARGER ALLSCHWILERSTRASSE 10, CH-4009 BASEL, SWITZERLAND"

11. Ortolani, S; Butturini, G; Malpaga, A; Cingarlini, S; Malfatti, V; Capelli, P; Ruzzenente, A; Regi, P; Vallerio, P; Grego, E; ,Role of Combined 68Ga-DOTATOC and 18F-FDG PET-CT in the Diagnostic Workup of Well Differentiated Pancreas Neuroendocrine Tumors (PanNETs): A Surgical Series,NEUROENDOCRINOLOGY,102,1-2,113-113,2015,"KARGER ALLSCHWILERSTRASSE 10, CH-4009 BASEL, SWITZERLAND"

12. Campostrini, Natascia; Udali, Silvia; Corbella, Michela; Guarini, Patrizia; Castagna, Annalisa; Pattini, Patrizia; Ruzzenente, Andrea; Guglielmi, Alfredo; Moruzzi, Sara; Ferrarini, Alberto; ,HEPCIDIN REPRESSION BY PROMOTER DNA HYPERMETHYLATION IN NON-VIRAL HEPATOCELLULAR CARCINOMA,AMERICAN JOURNAL OF HEMATOLOGY,91,3,E81-E81,2016,"WILEY-BLACKWELL 111 RIVER ST, HOBOKEN 07030-5774, NJ USA"

13. Ruzzenente, Andrea; Bagante, Fabio; Bertuzzo, Francesca; Aldrighetti, Luca; Ercolani, Giorgio; Ferrero, Alessandro; Giuliante, Felice; Torzilli, Guido; Grazi, Gian Luca; Guglielmi, Alfredo; ,348 Neuroendocrine Liver Metastasis: A Novel Nomogram Predicting the Prognosis of Patients after Liver Resection,Gastroenterology,150,4,S1175,2016,Elsevier

14. Ruzzenente, Andrea; Bagante, Fabio; Dorna, Adriano E; Conci, Simone; Campagnaro, Tommaso; Pedrazzani, Corrado; Iacono, Calogero; Guglielmi, Alfredo; ,Tu1730 A Clinical Score Predicting the Occurence of Liver-Related Complications Following Hepatectomy,Gastroenterology,150,4,S1259,2016,Elsevier

15. Corbella, Michela; Udali, Silvia; Guarini, Patrizia; Moruzzi, Sara; Girelli, Domenico; Pattini, Patrizia; Ruzzenente, Andrea; Guglielmi, Alfredo; Ferrarini, Alberto; Delledonne, Massimo; ,EPIGENETIC REGULATION OF HEPCIDIN EXPRESSION IN NON-VIRAL HEPATOCELLULAR CARCINOMA: RESULTS OF A GENOME-WIDE STUDY,AMERICAN JOURNAL OF HEMATOLOGY,88,5,E180-E181,2013,"WILEY-BLACKWELL 111 RIVER ST, HOBOKEN 07030-5774, NJ USA"

16. Iacono, Calogero; Ruzzenente, Andrea; Conci, Simone; Bacchelli, Claudio; Campagnaro, Tommaso; Valdegamberi, Alessandro; Pedrazzani, Corrado; Bertuzzo, Francesca; Verlato, Giuseppe; Guglielmi, Alfredo; ,Mo1619 A 30-Years Celebration of First Description of Central Pancreatectomy (The Dagradi-Serio-Iacono Operation): Historical Outline and Surgical Outcome,Gastroenterology,146,5,S-1068,2014,Elsevier

17. Cingarlini, S; Trentin, C; Ottolani, S; Grego, E; D'Onofrio, M; Scarpa, A; Ruzzenente, A; Butturini, G; Capelli, P; Tortora, G; ,Streptozotocin/5-Fluorouracil (STZ/5FU) Chemotherapy in G1-G2 Pancreatic Neuroendocrine Tumors (pNETs): Single Institution Experience,NEUROENDOCRINOLOGY,99,3-4,266-266,2014,"KARGER ALLSCHWILERSTRASSE 10, CH-4009 BASEL, SWITZERLAND"

18. Vallerio, P; Cingarlini, S; Trentin, C; Grego, E; D'Onofrio, M; Butturini, G; Davi, M; Scarpa, A; Capelli, P; Ruzzenente, A; ,Normal Tissue Perfusion Changes During Everolimus Treatment: Preliminary Results from a Functional Vascular Study,NEUROENDOCRINOLOGY,99,3-4,264-264,2014,"KARGER ALLSCHWILERSTRASSE 10, CH-4009 BASEL, SWITZERLAND"



19. Andrea Ruzzenente, Calogero Iacono, Simone Conci, Fabio Bagante, Elisabetta Dolci, Alessandro

Valdegamberi, Adriano Dorna, Guido Mantovani, Mirko D’Onofrio and Alfredo Guglielmi COMPUTED TOMOGRAPHIC PERFUSION (CTP) OF THE LIVER: A NEW NON-INVASIVE LIVER FUNCTION TEST? HPB 2014, 16 (Suppl. 2), 79

20. Andrea Ruzzenente, Alessandro Valdegamberi, Calogero Iacono, Fabio Bagante,Francesca Bertuzzo, Tommaso Campagnaro, Simone Conci, Guido Mantovani, Michela De Angelis and Alfredo Guglielmi. A NEW PROGNOSTIC NOMOGRAM FOR PERIHILAR CHOLANGIOCARCINOMA AFTER SURGICAL RESECTION: COMPARISON WITH THE CURRENT STAGING SYSTEMS. HPB 2014, 16 (Suppl. 2), 139

21. Andrea Ruzzenente, Fabio Bagante, Calogero Iacono, Federica Pedica, Matteo Brunelli, Paola

Capelli, Alessandro Valdegamberi, Simone Conci, Aldo Scarpa and Alfredo Guglielmi. C-MYC DEREGULATION AS NEW PREDICTIVE FACTOR FOR EARLY RECURRENCE OF HCC AFTER SURGICAL RESECTION. HPB 2014, 16 (Suppl. 2), 189

22. Andrea Ruzzenente, Alessandro Valdegamberi, Calogero Iacono, Simone Conci, Fabio Bagante, Tommaso Campagnaro, Marco Costa, Marco Piccino, MichelaDe Angelis and Alfredo Guglielmi. PREDICTING THE POST- HEPATECTOMY LIVER FAILURE: APPLICATION AND INTERNAL VALIDATION OF A NEW MATHEMATICAL MODEL. HPB 2014, 16 (Suppl. 2), 214

23. Corbella M., Udali S., Guarini P., Moruzzi S., Girelli D., Pattini P., Ruzzenente A., Guglielmi A., Ferrarini A., Delledonne M., Choi S-W., Friso S (2013). Epigenetic Regulation Of Hepcidin Expression In Non-Viral Hepatocellular Carcinoma: Results Of A Genome-Wide Study. AMERICAN JOURNAL OF HEMATOLOGY, vol. 88, p. 180-181, ISSN: 0361-8609

24. Udali Silvia, Guarini Patrizia, Ruzzenente Andrea, Guglielmi Alfredo, Ferrarini Alberto, Tononi Paola, Pattini Patrizia, Moruzzi Sara, Choi Sang-Woon, Delledonne Massimo, Friso Simonetta (2013). Genome-wide DNA methylation and gene expression profiles analysis show novel regulatory pathways in alcohol-related hepatocellular carcinoma. FASEB JOURNAL, vol. 27, p. 68, ISSN: 0892-6638

25. Ruzzenente A, T. Campagnaro, C. Iacono, A. Valdegamberi, F. Bagante, M. De Angelis and A. Guglielmi (2012) AGGRESSIVE TREATMENT OF RECURRENCE OF PERI-HILAR AND INTRAHEPATIC CHOLANGIOCARCINOMA AFTER SURGICAL RESECTION CAN IMPROVE LONG TERM SURVIVAL. HPB 2012, 14 (Suppl. 2), 15C.

26. Iacono, G. Verlato, A. Ruzzenente, T. Campagnaro, C. Bacchelli, A. Valdegamberi, M. De Angelis and A. Guglielmi. A 30-YEAR CELEBRATION OF ‘THE DAGRADI-SERIO-IACONO OPERATION’. SYSTEMATIC REVIEW OF CENTRAL PANCREATECTOMY AND META-ANALYSIS VERSUS DISTAL PANCREATECTOMY (DP). HPB 2012, 14 (Suppl. 2), 80

27. Ruzzenente A, T. Campagnaro, G. Ercolani, F. Giovinazzo, A. Dazzi, C. Bassi, A. D. Pinna andA.

Guglielmi. PROGNOSTIC SIGNIFICANCE OF LYMPH-NODE METASTASES IN CHOLANGIOCARCINOMA, RESULTS OF MULTI-INSTITUTIONAL STUDY ON 481 PATIENTS. HPB 2012, 14 (Suppl. 2), 122

28. G. Ercolani, A. Dazzi, F.Giovinazzo, A. Ruzzenente, M. Cescon, P. Guglielmi, C. Bassi and A. D. Pinna . PATHOLOGIC CHARACTERISTICS OF INTRAHEPATIC, PERI-HILAR AND DISTAL CHOLANGIOCARCINOMA: A RETROSPECTIVE ANALYSIS OF A MULTICENTRIC DATABASE ON 481 RESECTED PATIENTS. HPB 2012, 14 (Suppl. 2), 114

29. Ruzzenente, A. Valdegamberi, C. Iacono, S. Conci, M. De Angelis and A. Guglielmi. INTRAOPERATIVE CONTRAST- ENHANCED ULTRASONOGRAPHY: ASSESSMENT OF EFFICACY IN COLORECTAL LIVER METASTASES AFTER PREOPERATIVE CHEMOTHERAPY. HPB 2012, 14 (Suppl. 2), 418



30. Iacono C, Ruzzenente A, Valdegamberi A, Bertuzzo F, Conci S, Bagante F, Xillo L, Guglielmi A (2012). Dorsal Pancreatectomy: An Alternative to the Total Pancreatectomy. Report of Two Cases and Review of the Literature. JOP. JOURNAL OF THE PANCREAS, ISSN: 1590-8577

31. Valdegamberi A, Ruzzenente A, Iacono C, Campagnaro T, Conci S, Baldiotti E, Bagante F, Guglielmi A. (2012). 'Recurrence of cholangiocarcinoma after surgical treatment: an analysis of modes of occurrence, risk factors, and results of treatment.. In: 7° congresso del capitolo italiano IT-IHPBA. Bologna, 19-20 april 2012

32. Silvia Udali, Patrizia Guarini, Andrea Ruzzenente, Alfredo Guglielmi, Alberto Ferrarini, Paola Tononi, Patrizia Pattini, Sara Moruzzi, Sang-Woon Choi, Massimo Delledonne, Simonetta Friso (2012). Array-based genome-wide DNA methylation profiles and gene expression analyses show novel regulatory pathways in alcohol-related hepatocellular carcinoma . In: Annual Symposium: Epigenetic mechanisms in development and disease. p. P041, Leeds, United Kingdom, December 11-13, 2012

33. Conci S., Ruzzenente A., Iacono C., Valdegamberi A., Costa M., De Angelis M., Guglielmi A. (2012). Contrast-enhanced intraoperative ultrasonography is a valuable method to improve detection of colorectal liver metastases after preoperative chemotherapy.. In: 7° congresso del capitolo italiano IT-IHPBA. Bologna, 19-20 april 2012

34. Ruzzenente A, Campagnaro T, Valdegamberi A, Bertuzzo F, Bagante F, Iacono C, Guglielmi A (2012). Patterns and Prognostic Significance of Lymph-Node Dissection for Surgical Treatment of Peri-Hilar and Intrahepatic Cholangiocarcinoma. GASTROENTEROLOGY, vol. 142, p. S1077-S1078, ISSN: 0016-5085

35. Guglielmi A, Ruzzenente A, Valdegamberi A, Campagnaro T, Iacono C (2012). Right Hepatectomy With Caval Thrombectomy After Neoadjiuvant Therapy-TACE and Sorafenib-for HCC With Caval Thrombosis. GASTROENTEROLOGY, vol. 142, p. S1031, ISSN: 0016-5085

36. Ruzzenente A, Valdegamberi A, Campagnaro T, Conci S, Baldiotti E, Iacono C, Guglielmi A (2012). Risk Factors, Pattern of Onset and Result of Treatment of Recurrence After Liver Resection of Peri-Hilar and Intrahepatic Cholangiocarcinoma. GASTROENTEROLOGY, vol. 142, p. S1049, ISSN: 0016-5085

37. Ruzzenente A, Campagnaro T, Conci S, Valdegamberi A, Costa M, Baldiotti E, Iacono C, Guglielmi A (2012). Usefulness of Contrast-Enhanced Intraoperative Ultrasonography in Colorectal Liver Metastases After Preoperative Chemotherapy. GASTROENTEROLOGY, vol. 142, p. S1042, ISSN: 0016-5085

38. Guglielmi A, Ruzzenente A, Valdegamberi A, Campagnaro T, Iacono C (2011). Right Trisectionectomy With "en-bloc" Resection of Portal Vein for Peri-Hilar Cholangiocarcinoma. GASTROENTEROLOGY, vol. 140, p. S996, ISSN: 0016-5085

39. Ruzzenente A, Campagnaro T, Valdegamberi A, Conci S, Bagante F, Turcato G, Iacono C, Guglielmi A (2011). Surgical Resection Versus Local Ablation for HCC on Cirrhosis: Results From a Propensity Case-Matched Study. GASTROENTEROLOGY, vol. 140, p. S995, ISSN: 0016-5085

40. Iacono C, Verlato G, Ruzzenente A, Campagnaro T, Valdegamberi A, Bortolasi L, Tezza C, Guglielmi A (2011). Systematic Review of Central Pancreatectomy "The Dagradi-Serio-lacono Operation" and Meta-Analysis Versus Distal Pancreatectomy. GASTROENTEROLOGY, vol. 140, p. S1038-S1039, ISSN: 0016-5085

41. Guglielmi A., Ruzzenente A., Capra F., Campagnaro T., Valdegamberi A., Ieluzzi D., Turcato G., Iacono C. (2011). Surgical versus non surgical therapy of HCC on cirrhosis: results of an observational study of 692 cases. In: IX E-AHPBA Congress. Cape Town, South Africa, 12-16 April 2011

42. Guglielmi A., Ruzzenente A., Campagnaro T., Pachera S., Iacono C. (2010). Prognostic value of lymph node ratio after resection of peri-hilar cholangiocarcinoma.. In: IX IHPBA World Congress. Buenos Aires, Argentina, 18-22 April 2010



43. Guglielmi A, Ruzzenente A, Pachera S, Campagnaro T, Valdegamberi A, Iacono C. (2010). Surgical resection of HCC on cirrhosis: prognostic value of portal hypertension.. In: XXIII Congresso Nazionale SICO - Società Italiana di Chirurgia Oncologica,. Milano, Italia, 10-12 Giugno 2010

44. Guglielmi A, Ruzzenente A, Pachera S, Campagnaro T, Valdegamberi A, Iacono C. (2010). Surgical resection of HCC on cirrhosis: prognostic value of portal hypertension. In: IX IHPBA World Congress. Buenos Aires, Argentina, 18-22 April 2010

45. Guglielmi A, Ruzzenente A, Pachera S, Campagnaro T, Valdegamberi A, Turcato G, Bagante F, Iacono C (2010). Prognostic value of portal hypertension after surgical resection of HCC in cirrhotic patients. In: 6° IT-IHPBA Italian Chapter. Torino, Italia, 24-25 Settembre 2010

46. Guglielmi A, Ruzzenente A, Campagnaro T, Pachera S, Conci S, Iacono C. (2010). Prognostic value of lymph node ratio after resection of intrahepatic and peri-hilar cholangiocarcinoma. In: XXIII Congresso Nazionale SICO - Società Italiana di Chirurgia Oncologica. Milano, Italia, 10-12 Giugno 2010

47. Guglielmi A, Ruzzenente A, Campagnaro T, Valdegamberi A, Conci S, Iacono C. (2010). Mesohepatectomy estended to caudate lobe for perihilar cholangiocarcinoma.. In: 6° IT-IHPBA Italian Chapter. Torino, Italia, 24-25 Settembre 2010

48. Iacono C, Ruzzenente A, Campagnaro T, Pachera S, Conci S, Tezza C, Guglielmi A. (2010). Intrahepatic and perihilar cholangiocarcinoma: prognostic value of lymph node ratio after surgical resection. In: 6° IT-IHPBA Italian Chapter. Torino, Italia, 24-25 Settembre 2010

49. Ruzzenente A, D'Onofrio M, Pachera S, Martone E, Valdegamberi A, Campagnaro T, Iacono C, Guglielmi A (2009). Local Ablative Therapies for Hepatocellular Carcinoma: Does Immediate Contrast Enhanced Ultrasonography (CEUS) Predict Complete Necrosis At CT Follow Up?. GASTROENTEROLOGY, vol. 136, p. A915, ISSN: 0016-5085

50. D'Onofrio M, Ruzzenente A, Malagò R, Faccioli N, Pozzi Mucelli R (2009). Can immediate CEUS study after percutaneous treatment of focal liver lesions always predict complete necrosis at CT follow-up?. In: (ECR ) European Congress of Radiology 2009. EUROPEAN RADIOLOGY, vol. 19, p. B-683, ISSN: 0938-7994, Vienna, 6-10/03/2009

51. Ruzzenente A., Guglielmi A., Campagnaro T., Pachera S., Valdegamberi A., Capelli P., Nicoli P., Malfermoni G., Iacono C. (2009). Surgical treatment of peripheral intra-hepatic cholangiocarcinoma and peri-hilar cholangiocarcinoma: analysis of prognostic factors.. In: XXXII Congresso Nazionale SICO. Bari, Italia, 4-6 Giugno 2009

52. Ruzzenente A., Iacono C., Pachera S., Nicoli P., Fontana M., Guglielmi A. (2008). Is the early recurrence related with survival after surgical resection of hepatocellular carcinoma?. In: English American Hepato Pancreato Biliary Congress Annual Scientific Session and Postgraduate Course. S. Diego, California, March 27-30, 2008

53. Ruzzenente A., Capra F., Iacono C., Piccirillo G., Lunardi M., Pistoso S., Valdegamberi A., Guglielmi A. (2008). Is the liver resection justified in advanced hepatocellular carcinoma? Results of an observational study in 464 patients.. In: The 49th Annual Meeting of the Society for surgery of the Alimentary Tract.. HPB, ISSN: 1365-182X, S Diego, California., May 17-June 21, 2008

54. Ruzzenente A., Pachera S., Capra F., Calogero I., Valdegamberi A., Piccirillo G., Pistoso S., Guglielmi A. (2008). Liver resection for multinodular hepatocellular carcinoma. Lesson learn from observational study on 464 patients.. In: Congress of the European Hepato-Pancreato-Biliary Association. HPB, ISSN: 1365-182X, Athens, Greece., 18-20 June 2009

55. Pachera S., Ruzzenente A., Iacono C., Campagnaro T., Guglielmi A. (2009). Surgical intervention for hepatocellular carcinoma with obstructive jaundice due to Biliary tumor thrombus.. In: Congress of the



European Hepato-Pancreato-Biliary Association. HPB, ISSN: 1365-182X, Athens, Greece, 18-20 June 2009

56. Pedica F, Bortesi L, Montagna L, Pachera S, Ruzzenente A, Guglielmi A, Chilosi M, Menestrina F, Capelli P (2009). MUC5AC expression and its biological value in cholangiocarcinoma. VIRCHOWS ARCHIV, vol. 455, p. 110, ISSN: 0945-6317

57. Ruzzenente A, Pachera S, Campagnaro T, Valdegamberi A, Capelli P, Nicoli P, Iacono C, Guglielmi A (2009). Prognosis After Surgery of Cholangiocarcinoma: Peripheral Intra-Hepatic Cholangiocarcinoma Versus Peri-Hilar Cholangiocarcinoma. GASTROENTEROLOGY, vol. 136, p. A888, ISSN: 0016-5085

58. Montagnana M, Lippi G, Ruzzenente A, Fontana M, Iacono C, Salvagno GL, Guglielmi A, Guidi GC (2008). Biochemical evaluation of cardiac function in patients with hepatocarcinoma. CLINICAL CHEMISTRY, vol. 54, p. A84, ISSN: 0009-9147

59. Ruzzenente A, Capra F, Iacono C, Piccirillo G, Lunardi M, Pistoso S, Valdegamberi A, Guglielmi A (2008). Is liver resection justified in advanced hepatocellular carcinoma? Results of an observational study in 464 patients. GASTROENTEROLOGY, vol. 134, p. A850, ISSN: 0016-5085

60. Pedica F, Bortesi L, Capelli P, Pachera S, Ruzzenente A, Guglielmi A, Martignoni G, Chilosi M, Scarpa A, Menestrina F (2008). MUC5AC EXPRESSION AND ITS PROGNOSTIC VALUE IN CHOLANGIOCELLULAR CARCINOMA. ANTICANCER RESEARCH, vol. 28, p. 3441-3442, ISSN: 0250-7005

61. Manfredi R, Mehrabi S, Motton M, Mucelli RP, Ruzzenente A, Capelli P, Iacono C, Guglielmi A (2008). Preoperative assessment of intrahepatic cholangiocarcinoma: CT features with pathological correlation. GASTROENTEROLOGY, vol. 134, p. A880, ISSN: 0016-5085

62. Ruzzenente A, Iacono C, Campagnaro T, Capelli P, Mazzoldi S, Valdegamberi A, Nicoli P, Guglielmi A (2008). Significance of tissue expression of MUC5AC in hilar and intrahepatic cholangiocarcinoma. GASTROENTEROLOGY, vol. 134, p. A880, ISSN: 0016-5085

63. Iacono C., Ruzzenente A., Zugni C., Campagnaro T., Bortolasi L., Valdegamberi A., Guglielmi A. (2008). Surgical margin, lymph-node status, tumor differentiation, UICC stage and adjuvant therapy are relevant prognostic factors after resection in pancreatic cancer.. In: English American Hepato Pancreato Biliary Congress Annual Scientific Session and Postgraduate Course. HPB, ISSN: 1365-182X, S. Diego, California, March 27-30, 2008

64. Iacono C, Ruzzenente A, Campagnaro T, Valdegamberi A, Zugni C, Cantore M, Guglielmi A (2008). Surgeon's contribution to long term survival of pancreatic cancer. GASTROENTEROLOGY, vol. 134, p. A908, ISSN: 0016-5085

65. Iacono C., Cantore M., Ruzzenente A., Verlato G., Facci E., Campagnaro T., Mambrini A., Pachera S., Guglielmi A. (2007). Adjuvant chemotherapy is associated to good survival in patients underwent extended pancreaticoduodenenctomy for pancreatic cancer.. In: AHPBA VII American congress. Las Vegas, 19-22 April 2007

66. Ruzzenente A., Pachera S., Nicoli P., Piccirillo G., Campagnaro T., Iacono C., Guglielmi A. (2007). Influence Of Allogenic Blood Transfusion In Surgical Resection Of HCC.. In: VII European Congress of IHPBA. HPB, vol. 9, ISSN: 1365-182X, Verona, 8 June 2007

67. Ruzzenente A., Pachera S., Piccirillo G., Fontana M., Zugni C., Iacono C., Guglielmi A. (2007). Survival after surgical resection of hepatocellular carcinoma according to time-to-recurrence.. In: European Congress of IHPBA. Verona, 8 June 2007

68. Iacono C, Bortolasi L, Facci E, Frisini M, Ruzzenente A, Guglielmi A (2006). Has the Dagradi-Serio-



Iacono operation or central pancreatectomy been correctly applied in surgical practice?. GASTROENTEROLOGY, vol. 130, p. A884, ISSN: 0016-5085

69. Ruzzenente A, Sandri M, Iacono C, Pachera S, Pedrazzani C, Tasselli S, Guglielmi A (2006). Radiofrequency ablation for HCC in cirrhotic patients: Prognostic factors for survival. GASTROENTEROLOGY, vol. 130, p. A859, ISSN: 0016-5085

70. Iacono C., Cantore M., Ruzzenente A., Verlato G., Facci E., Zugni C., Campagnaro T., Mambrini A., Fontana M., Pachera S., Guglielmi A. (2006). Adjuvant chemotherapy is associated to good survival in patients underwent extended pancreaticoduodenenctomy for pancreatic cancer.. In: XXX Congresso Nazionale AISP. Milano, 21-23 Settembre 2006

71. Iacono C., Cantore M., Ruzzenente A., Verlato G., Facci E., Zugni C., Campagnaro T., Mambrini A., Fontana M., Pachera S., Guglielmi A. (2006). Pancreatic ductal carcinoma: adjuvant chemotherapy after extended pancreaticoduodenenctomy is associated to better survival versus surgery alone.. In: 7th World Congress of the International Hepato-Pancreato-Biliary Association. Edinburgh, 3 - 7 September 2006

72. Ruzzenente A., D’Onofrio M., Pachera S., Campagnaro T., Fontana M., Guglielmi A. (2006). RFA and TACE vs RFA in Hepatocellular Carcinoma in Cirrhotic Patients: Local Therapeutic Effects and Patients Outcome.. In: XIX Congresso Nazionale SPIGC. Bologna, 21–23 Giugno 2006

73. Guglielmi A., Ruzzenente A., D’Onofrio M., Pachera S., Valdegamberi A., Iacono C. (2006). Radiofrequency ablation vesrus surgical resection for the treatment of hepatocellular carcinoma in cirrhosis.. In: XX ISDS World congress. Rome, 29 Novembre-2 Dicembre 2006

74. Pachera S., Ruzzenente A., Valdegamberi A., Campagnaro T., Fontana M., Guglielmi A. (2006). Resection of metastatic malignant hemangiopericytoma of the liver with severe hypoglycemia due to production of insuline-like growth factor IGF-II.. In: Congresso Nazionale SPIGC. Bologna, 21–23 Giugno 2006

75. Ruzzenente A., Pachera S., Valdegamberi A., Fontana M., Campagnaro T., Guglielmi A. (2006). Survival of Cirrhotic Patients with HCC After RFA: Comparison of 7 Staging Systems. In: Congresso Nazionale SPIGC. Bologna, 21–23 Giugno 2006

76. Guglielmi A, Ruzzenente A, Pachera S (2005). Il trattamento dell’epatocarcinoma. In: 1° Convegno Nazionale degli Aggiornamenti in Epatologia. Verona , 6 Maggio 2005

77. GuglielmiA, Ruzzenente A, PAchera S (2005). La Chirurgia dei tumori delle vie biliari intraepatiche.. In: Società Italiana di Chirurgia, 107° Congresso Nazionale. Cagliari , 9-12 Ottobre 2005

78. Donataccio M, Ruzzenente A, Molfetta M, Pachera S, Genco B, Donataccio D, Guglielmi A, Polati E, Pinna E. (2004). Anastomosi Cavo-cavale laterolaterale nel trapianto di fegato, senza by pass venoso e senza shunt porto-cavale temporaneo. Esperienza prospettica del centro trapianti di fegato della Università di Verona.. In: 106° Congresso SIC. Roma , 17-20 ottobre

79. Donataccio M, Ruzzenente A, Molfetta M, Pachera S, Genco B, Donataccio D, Guglielmi A, Polati E, Pinna E. (2004). Il trapianto di fegato a Verona: Esperienza iniziale.. In: Congesso NITp. Ancona , 4-5 OTTOBRE 2004

80. Ruzzenente A, Donataccio M, Halmos O, Pachera S, Guglielmi A. (2002). Prognostic Factors for survival after RFA of HCC. Third International Meeting on Hepatocellular Carcinoma Eastern and Western Experiences.. In: Third International Meeting on Hepatocellular Carcinoma Eastern and Western Experiences.. Lodi , 21-22 Novembre

81. Guglielmi A., Ruzzenente A., Frameglia M. (1999). Il carcinoma pancreatico. Supporto e palliazione: Il ruolo della Chirurgia.. In: Giornate di Medicina Oncologica Integrata del Piemonte Orientale sul



Carcinoma pancreatico.. p. 104-109, Novara , 9-10 Dicembre 1999.

Il sottoscritto Andrea Ruzzenente, nato a Verona il 18/08/1973, codice fiscale n. RZZNDR73H18L781E, residente in Negrar, Via Giuseppe Verdi n. 5/a, C, dichiara che tutto quanto sopra riportato nel proprio curriculum vitae corrisponde a verità ai sensi delle norme in materia di dichiarazioni sostitutive di cui agli art. 46 e 47 del D.P.R. 445/2000;

Verona 1 Settembre 2017 Firma:______________________________


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