Evidence-Based Clinical Care
Coagulation Disorders DRG
MS DRG 813
Deliverables
Non-tunneled Central Venous Catheter
Removal Algorithm
Order Sets
Order Sets / Power Plans
Order Sets (Down Time Forms) Status Cerner Power Plan
SO-0031 EBCC Transfusion and Ordering
of Blood Products Updated
EBCC MED Transfusion and Ordering of
Blood Products
SO-0245 EBCC ED Transfusion and
Ordering of Blood Products Updated
EBCC ED Transfusion and Ordering of
Blood Products
SO-0001 Emergent Release of Blood
Product
Form Name
Change N/A
EBCC ED and MED Transfusion and Ordering
of Blood Products 1 of 2
EBCC ED and MED Transfusion and Ordering
of Blood Products 2 of 2
Education
eWINK+ - Central Venous Catheter Removal
Central Venous Catheter Removal-
RN Education in BHU
Evidence Based Research
Evidence Based Research
• (2016). Infusion therapy standards of practice. Norwood, MA: Infusion Nurses Society; Wolters Kluwer
• AABB, October 2107, Circular of Information: For the Use of Human Blood and Blood Components brochure, 74 pages,
ISBN 978-1-56395-956-1
• Alamri. (2011). Do We Need Premedication Before Coronary Angiography? A Controlled Clinical Trial. Cardiology
Research. doi: 10.4021/cr68w
• Baptist Hospital of Miami. (2013). Guidelines for Neuroaxial Anesthesia in the Anticoagulated Patient 2010 (Updated
2013). Provided by Neuroaxial Anesthesia
• Camp-Sorrell, D., & Matey, L. (2017). Access device standards of practice for oncology nursing. Pittsburgh, PA:
Oncology Nursing Society.
• Christopher, K. L. (2016). Spontaneous iris bleeding during cataract surgery in a patient with thrombocytopenia. Digital
Journal of Ophthalmology. doi: 10.5693/djo.02.2015.05.005
• Cuker, A., Arepally, G.M., Chong, B.H., Cines, D.B.,. . .Santesso, N (2018). American Society of Hematology 2018
guidelines for management of venous thromboembolism: heparin-induced thrombocytopenia Blood Advances 2018
2:3360-3392; doi: https://doi.org/10.1182/bloodadvances.2018024489
• Davidson, J. C., Rahim, S., Hanks, S. E., Patel, I. J., Tam, A. L., Walker, T. G., . . . Sarode, R. (2019). Society of
Interventional Radiology Consensus Guidelines for the Periprocedural Management of Thrombotic and Bleeding Risk in
Patients Undergoing Percutaneous Image-Guided Interventions—Part I: Review of Anticoagulation Agents and Clinical
Considerations. Journal of Vascular and Interventional Radiology. doi:10.1016/j.jvir.2019.04.016
Evidence Based Research
• Earhart, A. (2013). Central lines: Recognizing, preventing, and troubleshooting complications. American Nurse Today,
8(11), 1-9.
• Emergency Medicine: Coagulation Studies in Patients Presenting with Chest Pain with No Coagulopathy or Bleeding.
(n.d.). Retrieved from https://www.acepnow.com/article/emergency-medicine: coagulation-studies-in-patients-presenting-
with-chest-pain-with-no-coagulopathy-or-bleeding/
• Geiger, T. L., & Howard, S. C. (2007). Acetaminophen and Diphenhydramine Premedication for Allergic and Febrile
Nonhemolytic Transfusion Reactions: Good Prophylaxis or Bad Practice? Transfusion Medicine Reviews, 21(1), 1–12.
doi: 10.1016/j.tmrv.2006.09.001
• George, J.N. & Arnold, D.M. (2018). Approach to the adult with unexplained thrombocytopenia. In Wolters Kluwer (Ed.).
UptoDate. Retrieved June 11th, 2019, from https://www.uptodate.com/contents/ approach-to-the-adult-with-unexplained-
thrombocytopenia
• Hames, K. C. (2003). To premed or not to premed. Anaesthesia, 58(3), 297–297. doi: 10.1046/j.1365-
2044.2003.307327.x
• Heparin-Induced Thrombocytopenia (HIT). The Ohio State University Wexner Medical Center, Columbus, Ohio.
November 30th, 2016, Edition 4. The Ohio State University.
• Jaffe, T. A., Raiff, D., Ho, L. M., & Kim, C. Y. (2015). Management of Anticoagulant and Antiplatelet Medications in Adults
Undergoing Percutaneous Interventions. American Journal of Roentgenology, 205(2), 421–428. doi:
10.2214/ajr.14.13342. https://www.ajronline.org/doi/10.2214/AJR.14.13342
• Kaufman, R. M., Djulbegovic, B., Gernsheimer, T., Kleinman, S., Tinmouth, A. T., Capocelli, K. E., . . . Tobian, A. A.
(2015). Platelet Transfusion: A Clinical Practice Guideline From the AABB. Annals of Internal Medicine, 162(3), 205.
doi:10.7326/m14-1589
• Lee, T., Huang, J., Lee, K., Lai, C., Chen, S., & Kuo, C. (2014). The use of platelet transfusion in thrombocytopenic
patients for phacoemulsification. Taiwan Journal of Ophthalmology, 4(1), 52-55. doi:10.1016/j.tjo.2013.06.003
Evidence Based Research
• Lo GK, Juhl D, Warkentin TE, Sigouin CS, Eichler P, Greinacher A. Evaluation of pretest clinical score (4 T’s) for the
diagnosis of heparin-induced thrombocytopenia in two clinical settings. J Thromb Haemost 2006; 4: 759–65
• Mccarthy, C., Behravesh, S., Naidu, S., & Oklu, R. (2016). Air Embolism: Practical Tips for Prevention and Treatment.
Journal of Clinical Medicine, 5(11), 93. doi: 10.3390/jcm5110093
• Nagler, M., Bachmann, L. M., Cate, H. T., & Cate-Hoek, A. T. (2015). Diagnostic value of immunoassays for heparin-
induced thrombocytopenia: A systematic review and meta-analysis. Blood, 127(5), 546-557. doi:10.1182/blood-2015-07-
661215
• Patel, I. J., Rahim, S., Davidson, J. C., Hanks, S. E., Tam, A. L., Walker, T. G., . . . Weinberg, I. (2019). Society of
Interventional Radiology Consensus Guidelines for the Periprocedural Management of Thrombotic and Bleeding Risk in
Patients Undergoing Percutaneous Image-Guided Interventions—Part II: Recommendations. Journal of Vascular and
Interventional Radiology. doi:10.1016/j.jvir.2019.04.017
• Regional Anesthesia in the Patient Receiving Antithrombotic or Thrombolytic Therapy. (2018). Regional Anesthesia and
Pain Medicine, 43(5), 566. doi: 10.1097/aap.0000000000000807
• Sarai, M., & Tejani, A. M. (2012). Loop diuretics for patients receiving blood transfusions. Cochrane Database of
Systematic Reviews. doi: 10.1002/14651858.cd010138
• Sharma, S., Sharma, P., Tyler, L.N. (2011). Transfusion of Blood and Blood Products: Indications and Complications.
American Family Physician. 2011 Mar 15;83(6):719-724
• Slichter, S. J., Kaufman, R.M., Assmann, S.F., McCullough, J., Triulzi, D.J., Staruss, R.G.,…Granger, S. (2010). Dose of
Prophylactic Platelet Transfusions and Prevention of Hemorrhage. New England Journal Of Medicine 2010; 362:600-613.
DOI: 10.1056/NEJMoa0904084
• Stanworth, S. J. (2007). The Evidence-Based Use of FFP and Cryoprecipitate for Abnormalities of Coagulation Tests and
Clinical Coagulopathy. Hematology, 2007(1), 179-186. doi:10.1182/asheducation-2007.1.179
Evidence Based Research
• Szczepiorkowski, Z. M., & Dunbar, N. M. (2013). Transfusion guidelines: When to transfuse. Hematology, 2013(1), 638-
644. doi:10.1182/asheducation-2013.1.638
• Thacker, S., (2019). Long Term Strategies for Blood Products. Managing Outdating. 2019 Premier Annual Breakthroughs
Conference and Exhibition. Nashville, Tennessee, June 23rd-26th, 2019. Premier Connect.
• Veen, J. J., Nokes, T. J., & Makris, M. (2010). The risk of spinal haematoma following neuraxial anaesthesia or lumbar
puncture in thrombocytopenic individuals. British Journal of Haematology, 148(1), 15-25. doi:10.1111/j.1365-
2141.2009.07899.x
• Warkentin, T. E., & Anderson, J. A. (2016). How I treat patients with a history of heparin-induced thrombocytopenia.
Blood, 128(3), 348-359. doi:10.1182/blood-2016-01-635003
• Wong RSM, Saleh MN, Khelif A, et al. Safety and efficacy of long-term treatment of chronic/persistent ITP with
eltrombopag: final results of the EXTEND study.Blood. 2017;130(23):2527-2536. Blood, 131(6), 709–709. doi:
10.1182/blood-2017-12-823252
• Yuan, S. & Goldfinger, D. (2019). Clinical & laboratory aspects of platelet transfusion therapy. In Wolters Kluwer (Ed.).
UptoDate. Retrieved July 19th, 2019, from https://www.uptodate.com/contents/clinical-&-laboratory-aspects-of-platelet-
transfusion-therapy