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Evolution for Cardiac

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GE Healthcare Evolution for Cardiac Evolution for Cardiac with Infinia Hawkeye cuts scan time Dr. Tarik Belhocine Associate Director of Clinical Research London Health Sciences Centre Department of Nuclear Medicine London, Ontario, Canada Overview Evolution for Cardiac is an innovative SPECT reconstruction package for both gated and non-gated Tc-99m based myocardial perfusion imaging (MPI). This package improves image quality while reducing imaging time by up to 50 percent * . This method can be used with or without Hawkeye CT-based attenuation correction, providing corrections for image-degrading factors including photon scatter, soft tissue attenuation and collimator detector response. Image quality is clinically equivalent to that of the FBP/OSEM full time acquisition. Methods MPI studies were performed with a two-day gated rest-stress Tc-99m MIBI protocol, on an Infinia Hawkeye SPECT/CT system, using Evolution for Cardiac for reconstruction. This iterative reconstruction (IR) method incorporates collimator detector response correction for resolution recovery (RR), attenuation correction (AC) and scatter correction (SC). The half-time acquisition (10 sec/proj) processed wtih RR, AC and SC was compared to full-time acquisition (20 sec/proj) routinely processed with FBP and IRAC reconstruction methods. The stress test was performed with Dipyridamole plus cycling exercise. Patient A History A 68 year-old male with an intermediate pretest likelihood of CAD was referred for a pre-surgical workup. BMI = 31.3. Patient A Findings A definitely normal study. * For complete product details refer to the Evolution for Cardiac product data sheet (5240720HNF, version 6/2007) Patient A - Evolution for Cardiac with corrections for soft tissue attenuation, photon scatter and collimator detector response, applied to a 10-second projection study.
Transcript
Page 1: Evolution for Cardiac

GE Healthcare

Evolution for CardiacEvolution for Cardiac with Infinia™ Hawkeye™ cuts scan time

Dr. Tarik BelhocineAssociate Director of Clinical ResearchLondon Health Sciences CentreDepartment of Nuclear MedicineLondon, Ontario, Canada

OverviewEvolution for Cardiac is an innovative SPECT reconstruction packagefor both gated and non-gated Tc-99m based myocardial perfusionimaging (MPI). This package improves image quality while reducing imaging time by up to 50 percent*. This method can be used with or without Hawkeye CT-based attenuation correction, providing corrections for image-degrading factors including photon scatter, soft tissue attenuation and collimator detector response. Image quality is clinically equivalent to that of the FBP/OSEM full time acquisition.

MethodsMPI studies were performed with a two-day gated rest-stress Tc-99m MIBI protocol, on an Infinia Hawkeye SPECT/CT system, using Evolution for Cardiac for reconstruction. This iterativereconstruction (IR) method incorporates collimator detectorresponse correction for resolution recovery (RR), attenuationcorrection (AC) and scatter correction (SC). The half-time acquisition (10 sec/proj) processed wtih RR, AC and SC was compared to full-time acquisition (20 sec/proj) routinely processed with FBP and IRAC reconstruction methods. The stress test was performed with Dipyridamole plus cycling exercise.

Patient A HistoryA 68 year-old male with an intermediate pretest likelihood of CADwas referred for a pre-surgical workup. BMI = 31.3.

Patient A FindingsA definitely normal study.

* For complete product details refer to the Evolution for Cardiac product data sheet (5240720HNF, version 6/2007)

Patient A - Evolution for Cardiac with corrections for soft tissue attenuation, photon scatter and collimator detector response, applied to a 10-second projection study.imagination at work

Page 2: Evolution for Cardiac

Patient A - FBP reconstruction applied to a 20-second projection full-time study of the same patient.

Patient A - IR+AC reconstruction applied to a 20-second projection full-time study of the same patient.

Page 3: Evolution for Cardiac

Patient B HistoryA 78 year-old male with known CAD (2 previous MI’s) was exploredfor unstable angina. BMI = 21.8.

Patient B FindingsA definitely abnormal study demonstrating a myocardial infarctionin the antero-septo-apical region (LAD territory) with a peri-infarctresidual ischemia.

ConclusionThese studies illustrate the feasibility of Evolution for Cardiacprocessing for half-time SPECT/CT MPI, without compromising theclinical information.

London Health Sciences Centre (London, Ontario, Canada) continues to use Evolution for Cardiac in a research framework, evaluating the many promising perspectives for MPI in routine clinical use.

Patient B - Evolution for Cardiac with corrections for soft-tissue attenuation, photon scatter and collimator detector response, applied to a 10-secondprojection study.

Page 4: Evolution for Cardiac

© 2008 General Electric Company – All rights reserved. GE and GE Monogram are trademarks of General Electric Company.

Infinia and Hawkeye are registered trademarks of GE Healthcare.

General Electric Company, doing business asGE Healthcare.

GE Healthcare3000 North Grandview BlvdWaukesha, WI 53188U.S.A.www.gehealthcare.com

NU-0160-12.07-EN-US

Patient B - FBP reconstruction applied to a 20-second projection full-time study of the same patient.

Patient B - IR+AC reconstruction applied to a 20-secondprojection full-time study of the same patient.

imagination at work


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