Fall 2012Organic

Chemistry LabCHML211

Lab Schedule, Course Policies, and Safety

Information

Prerequisite/Required Materials

PREREQUISITE: Grade of “C” or better in CHM102!

REQUIRED TEXTS/SUPPLIES: 1.LAB MANUAL:

– Organic Chemistry: Chemistry 211-212 Laboratory Manual Fall 2010 Edition—previous editions are unacceptable

2.LAB NOTEBOOK:– Organic Chemistry Laboratory Notebook

3.SAFETY GLASSES/GOGGLES:– Can be glasses or goggles, as long as

they form a complete seal around eyes!

Course Website• https://learn.uncw.edu/webapps/login/

Lab Schedule

Exp. #

Experiment Title

*** Introduction to Lab: Policies, Safety, Report Formatting1 Structure, Intermolecular Forces, and Solubility4 TLC and HPLC Analysis of Nitroanilines6 Extraction of Analgesics 7 Recrystallization, Melting Point, and HPLC Analysis of

Analgesics3 Stereochemistry and Molecular Modeling of Cycloalkanes

Quiz 1(Exp. 1, 4, 6, 7)5 Column Chromatographic Separation of Nitroanilines 8 Bromination of Stilbene—Green Synthesis 2 Distillation and Gas Chromatography of Alkanes

Quiz 2 (Exp. 3, 5, 8)10 Acid-Catalyzed Dehydration of an Alcohol with

Rearrangement 9* Stereochemistry: Enantiomers and Diastereomers11 Conversion of an Alcohol to an Alkyl Halide with

Rearrangement12 Base-Promoted Elimination of HBr from an Alkyl Halide Lab

Checkout Quiz 3 (Exp. 2, 9, 10, 11, 12)

Actual dates

depend on lab day. Please

see your syllabus

for specific dates.

Attendance Policy• All labs are mandatory.

• No make-up labs for any reason.

• Missed lab = zero (regardless of reason). 

• Missing 3+ labs = F for course.

• Athletic events are NOT excused absences.

Grading• Lab is graded separately than lecture!

– Quizzes (45%)– Final Lab Reports (55%)

• Course Grading: – A = 90-100, B = 80-89, C = 70-79, D = 60-69, F =

59 and below. – Plus (+) or minus (-) grades may be awarded at

the discretion of the instructor.

Lab Quizzes• 3 lab quizzes , 3-5 experiments on each.

• Full experiment after all quizzes! Plan on staying for the entire lab period!

• Make up quizzes will only be allowed for excused absences. – To have a quiz absence excused, the

student must: • Email before beginning of lab• Bring doctor’s note

Final Lab Reports• All lab assignments will be available on

the course website.

• Final Lab Reports consist of:– Pre-Lab Assignments (20 pts)– In-Lab Assignments (20 pts)– Post-Lab Assignments (50 pts)– Lab Technique/Preparation (10 pts)

• Due dates announced by instructor.

• Late reports = 5% penalty per day– Once lab reports are returned to students graded,

NO MORE WILL BE ACCEPTED!

Lab Technique• You are responsible for your own

safety!– Be prepared and familiar with safety

hazards!– Wear proper shoes and eye protection!– Common sense and thinking are

REQUIRED.

• You are responsible for cleaning up after yourself!– YOU. Not your lab instructor. If we clean,

you pay.

Personal Electronics• Cell phone use WILL NOT BE tolerated.

– Turn ON SILENT OR VIBRATE before lab and PUT IT AWAY!

– YOURS rings = you leave = ZERO– Cannot use phone as calculator during quizzes!

• Laptops and desktop computers use is allowed for lab related activities ONLY.

• Ipod use is not acceptable in lab!

Other Issues• Please refer to the online

syllabus for information regarding:– Learning Outcomes– Academic Integrity– Students with Disabilities– Violence and Harassment

Safety in the Organic Lab

• Follow instructions at all times!

• Act responsibly at all times!

• No food or drinks on lab benches!

• Dress appropriately for lab!

• Come prepared! Know what you are going to do, and what the hazards are!

• Report all accidents to the instructor, no matter how small.

Acceptable Clothing for Lab…

• DO wear – Goggles/safety glasses– Closed-toe shoes– Tie back long hair

• DON’T wear– Sandals/flip-flops– Jewelry– Loose or baggy clothing

Lab Safety Equipment

Safety Shower Eyewash

Safety Goggles/glasses

Lab Safety Equipment

Fire Extinguisher Fume Hood

Accidents and Injuries

• Report ALL injuries to lab instructor IMMEDIATELY, no matter how minor.

• Be aware of hazards associated with each chemical and technique you will use in the experiment!

• Complete an Injury Report Form.

First Aid• Eye accidents: Wash eyes in stream of water

using eyewash station for 15 minutes!

• Chemical burns: Immediately flush the affected area with a large amount of water in the sink! Use safety shower if necessary!

• Thermal burns: Determine the type and extent of the burn. Take appropriate action.– 1st degree: red skin, no blisters.

• Immerse in cold water/apply ice.– 2nd degree: blisters.

• Immerse in cold water, then apply clean gauze.– 3rd degree: broken skin, tissue damage.

• Cover with clean gauze. Visit the Health Center.

First Aid• Bleeding, cuts, and abrasions:

– Clean wound with soap and warm water.– Apply pressure with clean gauze pad until

bleeding stops.– Cover wound with bandage or clean gauze pad

and secure.

• Poisoning:– If, after contact with, inhalation of, or accidental

ingestion of a chemical, you experience discoloration of the lips, a burning sensation in the throat, stomach cramps, nausea and vomiting, or confusion, seek treatment IMMEDIATELY for chemical poisoning!

UNCW Safety Contract• READ Laboratory Rules and Guidelines (p.

vii) CAREFULLY!

• READ, SIGN, AND SUBMIT safety contract (p. xi) to instructor!

Waste Disposal• Waste disposal procedures are at end

of the procedure for each experiment.

• If you do not know which waste goes where, ASK!

• NOTHING DOWN THE SINK!