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Figure 2A

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Figure 2A. A. 8. 6. HBV DNA (Log IU/mL). 4. 2. 100%. 0. 80%. WT. 60%. Respective proportions of variant populations. A181V. 40%. N236T. 20%. A181V + N236T. 0%. M0. M7. M14. M28. M35. M21. M42. M49. M56. ADV. ADV+LAM. Figure 2B. 10. B. 8. 6. HBV DNA Log IU/mL. - PowerPoint PPT Presentation
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Figure 2A ADV ADV+LAM 0% 100% 20% 40% 60% 80% M0 M7 M14 M21 M28 M35 M42 M49 M56 0 2 4 6 8 HBV DNA (Log IU/mL) WT A181V N236T A181V + N236T Respective proportions of variant populations A
Transcript
Page 1: Figure 2A

Figure 2A

ADV ADV+LAM

0%

100%

20%

40%

60%

80%

M0

M7

M14

M21

M28

M35

M42

M49

M56

0

2

4

6

8

HB

V D

NA

(Lo

g IU

/mL)

WT

A181V

N236T

A181V+ N236T

Res

pect

ive

prop

ortio

nsof

va

riant

pop

ulat

ions

A

Page 2: Figure 2A

Figure 2B

B

ADV ADV+LAM

M5

M10

M15

M20

M30

M35

M40

M45

0%

20%

40%

N236T

A181V + N236T

M25

60%

80%

WT

A181V

100%

2

4

6

8

10

0

HB

V D

NA

Log

IU

/mL

Res

pect

ive

prop

ortio

nsof

va

riant

pop

ulat

ions

M0

A181T + N236T

Page 3: Figure 2A

Figure 2C

C

ADV

0%

20%

40%

N236T

A181V + N236T

100%

60%

80%

0

2

4

6

8

10

WT

A181V

HB

V D

NA

Log

IU

/mL

Res

pect

ive

prop

ortio

nsof

va

riant

pop

ulat

ions

M0

M5

M10

M15

M20

M25

M30

M35

M40

M45

A181T

Page 4: Figure 2A

Figure 2D

HB

V D

NA

(Lo

g IU

/mL)

H

BV

DN

A (

Log

IU/m

L)

ADV

0%

20%

40%N236T

A181V+ N236T

100%

60%

80% WT

A181V

0

2

4

6

8D

M0

M5

M10

M15

M20

M25

Res

pect

ive

prop

ortio

nsof

va

riant

pop

ulat

ions

A181T

A181T + N236T

Page 5: Figure 2A

ADV ADVADV+LAM

0%0%

20%20%

40%40%

100%100%

60%60%

80%80%

M0M0

M7M7

M14M14

M21M21

M28M28

M35M35

M42M42

N236TN236T

A181V + N236TA181V + N236T

WTWT

A181VA181V

00

22

44

66

88

HB

V D

NA

(Lo

g IU

/mL)

H

BV

DN

A (

Log

IU/m

L)

Figure 2E

E

Res

pect

ive

prop

ortio

nsof

va

riant

pop

ulat

ions

A181T + N236TA181T + N236T

Page 6: Figure 2A

0

2

4

6

8

0 5 10 15 20 25 30 35 40 45 50 55

0

50

100

150

200

250

300

ADV

ADV

N236TN236T

A181V + N236TA181V + N236T

WTWT

A181VA181V

00

22

44

66

88

M0M0

M10M10

M20M20

M30M30

M40M40

M50M50

0%0%

20%20%

40%40%

100%100%

60%60%

80%80%

HB

V D

NA

(Lo

g IU

/mL)

H

BV

DN

A (

Log

IU/m

L)

Figure 2F

F

Res

pect

ive

prop

ortio

nsof

va

riant

pop

ulat

ions

A181T + N236TA181T + N236T

Page 7: Figure 2A

Figure 2G

G

ADV

0%0%

20%20%

40%40%

100%100%

60%60%

80%80%

M0M0

M7M7

M14M14 M

21M21

M28M28

M35M35

M42M42

M48M48

ADV ADV+LAM

A181TA181T

N236TN236T

WTWT

A181VA181V

00

22

44

66

88

1010

HB

V D

NA

(Lo

g IU

/mL)

H

BV

DN

A (

Log

IU/m

L)

Res

pect

ive

prop

ortio

nsof

va

riant

pop

ulat

ions


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