Date post: | 31-Oct-2014 |
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Transcription and Translation Flip Book
By: Ivy Phillips and Hunter Smith
Transcription
Cell Nucleu
s
Cell Nucleu
s
Cell Nucleu
s
Cell Nucleu
s
DNA Strand
RNA Polymerase
Step 1- RNA polymerase binds to DNA and unwinds it
RNA PolymeraseTAC GCA AGC ATG CGT CGC
ATG CGT TCG TAC GCA GCG
Step 1- RNA polymerase binds to DNA and unwinds it
RNA Polymerase
TAC GCA AGC ATG CGT CGC GGG AAA ACG CCC ATC
ATG CGT TCG TAC GCA GCG CCC TTT TGC GGG TAG
Coding Region
Step 1- RNA polymerase binds to DNA and unwinds it
TAC GCA AGC ATG CGT CGC GGG AAA ACG CCC ATC
ATG CGT TCG TAC GCA GCG CCC TTT TGC GGG TAG
Promoter Region
RNA Polymerase Start Codon
Step 2- RNA polymerase binds to promoter region of DNA
TAC GCA AGC ATG CGT CGC GGG AAA ACG CCC ATC
ATG CGT TCG TAC GCA GCG CCC TTT TGC GGG TAG
RNA PolymeraseAUG CGU
Step 3- RNA polymerase reads DNA and creates mRNA
mRNA strand
TAC GCA AGC ATG CGT CGC GGG AAA ACG CCC ATC
ATG CGT TCG TAC GCA GCG CCC TTT TGC GGG TAG
RNA PolymeraseAUG CGU UCG UAC
Step 3- RNA polymerase reads DNA and creates mRNA
TAC GCA AGC ATG CGT CGC GGG AAA ACG CCC ATC
ATG CGT TCG TAC GCA GCG CCC TTT TGC GGG TAG
RNA PolymeraseAUG CGU UCG UAC GCA GCG
Step 3- RNA polymerase reads DNA and creates mRNA
TAC GCA AGC ATG CGT CGC GGG AAA ACG CCC ATC
ATG CGT TCG TAC GCA GCG CCC TTT TGC GGG TAG
RNA PolymeraseAUG CGU UCG UAC GCA GCG CCC UUU
Step 3- RNA polymerase reads DNA and creates mRNA
RNA Polymerase
TAC GCA AGC ATG CGT CGC GGG AAA ACG CCC ATC
ATG CGT TCG TAC GCA GCG CCC TTT TGC GGG TAG
Termination Sequence
AUG CGU UCG UAC GCA GCG CCC UUU UGC GGG UAG
Step 3- RNA polymerase reads DNA and creates mRNA
RNA Polymerase
TAC GCA AGC ATG CGT CGC GGG AAA ACG CCC ATC
ATG CGT TCG TAC GCA GCG CCC TTT TGC GGG TAG
Stop Codon
AUG CGU UCG UAC GCA GCG CCC UUU UGC GGG UAG
Step 4- RNA polymerase hits stop codon and releases mRNA
Cell Nucleu
s
AUG CGU UCG UAC GCA GCG CCC UUU UGC GGG UAG
Step 5- mRNA leaves nucleus and enters cytoplasm
Cell Nucleu
s
AUG CGU UCG UAC GCA GCG CCC UUU UGC GGG UAG
Step 5- mRNA leaves nucleus and enters cytoplasm
Nuclear Pore
Cytoplasm
Cell Nucleu
s
Cytoplasm
AUG CGU UCG UAC GCA GCG CCC UUU UGC GGG UAG
Step 5- mRNA leaves nucleus and enters cytoplasm
Translation
Cell Cytoplasm
RibosomerRN
A
Step 1- rRNA forms ribosome
Cell Cytoplasm
AUG CGU UCG UAC GCA GCG CCC UUU UGC GGG UAG
mRNA Strand
Step 2- mRNA binds to ribosome and is read
Start Codon
Cell Cytoplasm
AUG CGU UCG UAC GCA GCG CCC UUU UGC GGG UAG
mRNA Strand
Step 3- tRNA proof reads mRNA and transfers amino acids
tRNA
UAC
amino acid
Cell Cytoplasm
AUG CGU UCG UAC GCA GCG CCC UUU UGC GGG UAG
mRNA Strand
Step 3- tRNA proof reads mRNA and transfers amino acids
UAC GCA
Cell Cytoplasm
AUG CGU UCG UAC GCA GCG CCC UUU UGC GGG UAG
mRNA Strand
UAC GCA
Peptide Bond
Step 4- amino acids attached to tRNA bind with peptide bond
Anti-codon
Cell Cytoplasm
AUG CGU UCG UAC GCA GCG CCC UUU UGC GGG UAG
mRNA Strand
GCA
Step 4- amino acids attached to tRNA bind with peptide bond
Cell Cytoplasm
AUG CGU UCG UAC GCA GCG CCC UUU UGC GGG UAG
mRNA Strand
GCA AGC
Step 4- amino acids attached to tRNA bind with peptide bond
Cell Cytoplasm
AUG CGU UCG UAC GCA GCG CCC UUU UGC GGG UAG
mRNA Strand
AGC
Step 4- amino acids attached to tRNA bind with peptide bond
Cell Cytoplasm
AUG CGU UCG UAC GCA GCG CCC UUU UGC GGG UAG
mRNA Strand
AGC AUG
Step 4- amino acids attached to tRNA bind with peptide bond
Cell Cytoplasm
AUG CGU UCG UAC GCA GCG CCC UUU UGC GGG UAG
mRNA Strand
AUG
Step 4- amino acids attached to tRNA bind with peptide bond
Cell Cytoplasm
AUG CGU UCG UAC GCA GCG CCC UUU UGC GGG UAG
mRNA Strand
AUG CGU
Step 4- amino acids attached to tRNA bind with peptide bond
Cell Cytoplasm
AUG CGU UCG UAC GCA GCG CCC UUU UGC GGG UAG
mRNA Strand
CGU
Step 4- amino acids attached to tRNA bind with peptide bond
Cell Cytoplasm
AUG CGU UCG UAC GCA GCG CCC UUU UGC GGG UAG
mRNA Strand
CGU CGC
Step 4- amino acids attached to tRNA bind with peptide bond
Cell Cytoplasm
AUG CGU UCG UAC GCA GCG CCC UUU UGC GGG UAG
mRNA Strand
CGC
Step 4- amino acids attached to tRNA bind with peptide bond
Cell Cytoplasm
AUG CGU UCG UAC GCA GCG CCC UUU UGC GGG UAG
mRNA Strand
CGC GGG
Step 4- amino acids attached to tRNA bind with peptide bond
Cell Cytoplasm
AUG CGU UCG UAC GCA GCG CCC UUU UGC GGG UAG
mRNA Strand
GGG
Step 4- amino acids attached to tRNA bind with peptide bond
Cell Cytoplasm
AUG CGU UCG UAC GCA GCG CCC UUU UGC GGG UAG
mRNA Strand
GGG AAA
Step 4- amino acids attached to tRNA bind with peptide bond
Cell Cytoplasm
AUG CGU UCG UAC GCA GCG CCC UUU UGC GGG UAG
mRNA Strand
AAA
Step 4- amino acids attached to tRNA bind with peptide bond
Cell Cytoplasm
AUG CGU UCG UAC GCA GCG CCC UUU UGC GGG UAG
mRNA Strand
AAA ACG
Step 4- amino acids attached to tRNA bind with peptide bond
Cell Cytoplasm
AUG CGU UCG UAC GCA GCG CCC UUU UGC GGG UAG
mRNA Strand
ACG
Step 4- amino acids attached to tRNA bind with peptide bond
Cell Cytoplasm
AUG CGU UCG UAC GCA GCG CCC UUU UGC GGG UAG
mRNA Strand
ACG CCC
Step 4- amino acids attached to tRNA bind with peptide bond
Cell Cytoplasm
AUG CGU UCG UAC GCA GCG CCC UUU UGC GGG UAG
mRNA Strand
CCC
Step 4- amino acids attached to tRNA bind with peptide bond
Cell Cytoplasm
AUG CGU UCG UAC GCA GCG CCC UUU UGC GGG UAG
mRNA Strand
CCC AUC
STOP
Stop Codon
Amino acids
Met Arg Ser Tyr Ala Ala Pro Phe Cys Gly
Step 5- Ribosome hits stop codon and completes the protein
Completed Protein
Summary
Transcription:First, RNA polymerase binds to DNA and unwinds it. Then, RNA polymerase binds to promoter region of DNA. After that, RNA polymerase reads DNA and creates mRNA. Then, RNA polymerase hits a stop codon and releases mRNA. Last, mRNA leaves nucleus and enters cytoplasm.
Translation:First, rRNA forms ribosome. Then, mRNA binds to ribosomes and is read. After that, tRNA proof reads mRNA and transfers amino acids. Then, amino acids attached to the tRNA and bind with the peptide bond. Last, ribosome hits stop codon and completes the protein.