WATCHING A GENE AT WORK AND DNA FACTORY BUILDS UP

STEAM

Luz Eugenia Pérez Jaramillo 3rd Semester

Medicine Student

THE GENETIC REVOLUTION

Has a real effect and changein the last years, thatsituation permit us see theworld with the eyes of thesolution.

The “boom” of the geneticrepresents nowadays thesolution for things that wehad considered imposible.

With these news, I canobserve the realdevelopment in investigationabout genetic topics.

WATCHING A GENE AT WORKNATURE MEDICINE JOURNAL. JULY 18, 2010

WATCHING A GENE AT WORK

Scientists have viewed thereal-time dynamics of geneexpression, thatinvestigations for give to thescience a new ideas of themechanism that use eachone of the cells.

They explain variation amonggenetically identical cells andthe molecular processes thatlead to cancer.

WATCHING A GENE AT WORK

The late 1990s, researchersdeveloped a technique to taggenes so that they produce afluorescent signal the momentthey are transcribed into proteinblueprints known as messengerRNA.

Researchers have imagedindividual genes in bacteria andsingle-celled animals they seem toflicker on and off in bursts as theyproduce mRNA

WATCHING A GENE AT WORK

The researchers wereable to work out thedifferent mechanics oftranscription betweenthe human and viralpromoter.

Cells with the normalpromoter shut down forabout 20 minutes every200 minutes, whereas thecells with the viralpromoter remainedactive for a 10-hourstretch

WATCHING A GENE AT WORK

PERSONAL OPINION

Know the real process that realize the cell in its geneexpression, implies for the actual world manypossibilities for resolve important medical unknowns,and of these manner begin to search answers for use inall the people who need it.

DNA FACTORY BUILDS UP STEAMNature Medicine Journal. July 22, 2010

DNA FACTORY BUILDS UP STEAM

BIOFAB aims to supplysynthetic biologists witha collection of geneticparts that they can use intheir experiments.

Synthetic biologists aimto redesign bacterial cellsfor useful ends, such asproducing biofuels orcreating new types ofmedicines.

DNA FACTORY BUILDS UP STEAM

The pilot project tested adozen or so of the mostcommonly used genepromoters and segments ofDNA that encode ribosome-binding sites to determinewhether they behaveconsistently in differentcellular contexts.

DNA FACTORY BUILDS UP STEAM

Another continuingBIOFAB project is tocreate a bookshelf ofreference tools testedunder conditions used incommercial metabolicengineering.

BIOFAB isn't alone inworking on suchproblems on acommunity-wide scale.

PERSONAL OPINION

Now is real! We can buy parts ofDNA! That gives us thepossibility of many goodthings for resolve problemsthat affect the actual world.Cancer, contamination and somany factors are ending withthe live of all people; inspecial with the actual optionthat is of a “simple” mannerprevent, change and resolvethe illness since the beginning.

DNA FACTORY BUILDS UP STEAM

MEDICAL UTILITY

MEDICAL UTILITY

The development of the cellular biology brings to the medical personal so many important instruments for resolve some actual problems

MEDICAL UTILITY

We can know the specific mechanism that uses the cellin the process and development of some pathology thatnowadays doesn’t know the real cure.

MEDICAL UTILITY

The ADN implies for the medicine world a new necessityfor use in all the situations, and can be an additionalstrategy with the first case for of these manner locatethe section of DNA for cure a pathology, after theystudied the specific patient.

BIBLIOGRAPHY

MARTINEZ SÁNCHEZ, Lina María. Biología molecular. 5.ed. Medellín: UPB. Fac. de Medicina, 2009. 153-154 p.

Borrell, Brendan. Watching a gene at work. NatureMedicine Journal. 2010 July 18 [Epud ahead print].

Katsnelson, Alla. DNA factory builds up steam. NatureMedicine Journal. 2010 July 22 [Epud ahead print].

THANKS!!