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Front Matter Source: Proceedings of the National Academy of Sciences of the United States of America, Vol. 94, No. 20 (Sep. 30, 1997), pp. i-viii Published by: National Academy of Sciences Stable URL: http://www.jstor.org/stable/43361 . Accessed: 03/05/2014 16:07 Your use of the JSTOR archive indicates your acceptance of the Terms & Conditions of Use, available at . http://www.jstor.org/page/info/about/policies/terms.jsp . JSTOR is a not-for-profit service that helps scholars, researchers, and students discover, use, and build upon a wide range of content in a trusted digital archive. We use information technology and tools to increase productivity and facilitate new forms of scholarship. For more information about JSTOR, please contact [email protected]. . National Academy of Sciences is collaborating with JSTOR to digitize, preserve and extend access to Proceedings of the National Academy of Sciences of the United States of America. http://www.jstor.org This content downloaded from 130.132.123.28 on Sat, 3 May 2014 16:07:02 PM All use subject to JSTOR Terms and Conditions
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Front MatterSource: Proceedings of the National Academy of Sciences of the United States of America,Vol. 94, No. 20 (Sep. 30, 1997), pp. i-viiiPublished by: National Academy of SciencesStable URL: http://www.jstor.org/stable/43361 .

Accessed: 03/05/2014 16:07

Your use of the JSTOR archive indicates your acceptance of the Terms & Conditions of Use, available at .http://www.jstor.org/page/info/about/policies/terms.jsp

.JSTOR is a not-for-profit service that helps scholars, researchers, and students discover, use, and build upon a wide range ofcontent in a trusted digital archive. We use information technology and tools to increase productivity and facilitate new formsof scholarship. For more information about JSTOR, please contact [email protected].

.

National Academy of Sciences is collaborating with JSTOR to digitize, preserve and extend access toProceedings of the National Academy of Sciences of the United States of America.

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PROCEEDINGS OF THE

NATIONAL ACADEMY OF SCIENCES

OF THE UNITED STATES OF AMERICA

September 30, 1997 Volume 94/ Number 20

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PROCEEDINGS OF THE

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Officers of the Academy

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14,'sO III Lj

PROCEEDINGS OF THE

NATIONAL ACADEMY OF SCIENCES

OF THE UNITED STATES OF AMERICA

September 30, 1997 Volume 94, Number 20 pp. 10487-11108

Table of Contents

Commentaries

Energy sensors for aerotaxis in Escherichia coli: 10487-10489 Something old, something new

Ann M. Stock

Tetrahymena: The key to the genetic analysis of 10490-10492 the regulated pathway of polypeptide secretion?

John C. Hutton

Hydrogen bonding revisited: Geometric selection as a 10493-10495 principal determinant of DNA replication fidelity

Myron F. Goodman

The immunologist's grail: Vaccines that generate 10496-10498 cellular immunity

Margaret A. Liu

Are the current three-site models valid descriptions of 10499-10500 the ribosomal elongation cycle?

Knud H. Nierhaus, Ralf Jiinemann, and Christian M. T. Spahn

Inaugural Articles

The cloud-ionosphere discharge: A newly observed 10512-10519 thunderstorm phenomenon

John R. Winckler

Ordinary representations and modular forms 10520-10527 C. M. Skinner and A. J. Wiles

Structure at 2.7 A resolution of the Paracoccus 10547-10553 denitrificans two-subunit cytochrome c oxidase complexed with an antibody Fv fragment

Christian Ostermeier, Axel Harrenga, Ulrich Ermler, and Hartmut Michel

Physical Sciences

ASTRONOMY

Implications of a possible clustering of 10501-10505 highest-energy cosmic rays

Gunter Sigl, David N. Schramm, Sangjin Lee, and Christopher T. Hill

CHEMISTRY

A thymidine triphosphate shape analog lacking 10506-10511 Watson-Crick pairing ability is replicated with high sequence selectivity

Sean Moran, Rex X.-F. Ren, and Eric T. Kool

GEOPHYSICS

The cloud-ionosphere discharge: A newly observed 10512-10519 thunderstorm phenomenon

John R. Winckler

iii

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Contents

MATHEMATICS

Ordinary representations and modular forms 10520-10527 C. M. Skinner and A. J. Wiles

PHYSICS

Broken symmetry and critical transport properties 10528-10531 of random metals

J. C. Phillips

Critical transport properties of random metals in 10532-10535 large magnetic fields

J. C. Phillips

Biological Sciences

AGRICULTURAL SCIENCES

CytA enables CryIV endotoxins of Bacillus 10536-10540 thuringiensis to overcome high levels of CryIV resistance in the mosquito, Culex quinquefasciatus

M. C. Wirth, G. P. Georghiou, and B. A. Federici

BIOCHEMISTRY

The Aer protein and the serine chemoreceptor Tsr 10541-10546 independently sense intracellular energy levels and transduce oxygen, redox, and energy signals for Escherichia coli behavior

Anuradha Rebbapragada, Mark S. Johnson, Gordon P. Harding, Anthony J. Zuccarelli, Hansel M. Fletcher, Igor B. Zhulin, and Barry L. Taylor

Structure at 2.7 A resolution of the Paracoccus 10547-10553 denitrificans two-subunit cytochrome c oxidase complexed with an antibody Fv fragment

Christian Ostermeier, Axel Harrenga, Ulrich Ermler, and Hartmut Michel

Polyvalent binding to carbohydrates immobilized 10554-10559 on an insoluble resin

Rui Liang, Jennifer Loebach, Nina Horan, Min Ge, Chris Thompson, Lin Yan, and Daniel Kahne

Stabilization of microtubule dynamics by 10560-10564 estramustine by binding to a novel site in tubulin: A possible mechanistic basis for its antitumor action

Dulal Panda, Herbert P. Miller, Khalid Islam, and Leslie Wilson

Strained DNA is kinked by low concentrations 10565-10570 of Zn2+

Wenhai Han, Mensur Dlakic, Yinwen Judy Zhu, S. M. Lindsay, and Rodney E. Harrington

Structure and function in rhodopsin: Packing of 10571-10576 the helices in the transmembrane domain and folding to a tertiary structure in the intradiscal domain are coupled

John Hwa, Pere Garriga, Xun Liu, and HI. Gobind Khorana

Rhodopsin kinase: Expression in baculovirus-infected 10577-10582 insect cells, and characterization of post-translational modifications

Kiweon Cha, Christophe Bruel, James Inglese, and H. Gobind Khorana

Subunit rotation in Escherichia coli F0F1-ATP 10583-10587 synthase during oxidative phosphorylation

Yuantai Zhou, Thomas M. Duncan, and Richard L. Cross

The orphan nuclear receptor LXRa is positively 10588-10593 and negatively regulated by distinct products of mevalonate metabolism

Barry Marc Forman, Benfang Ruan, Jasmine Chen, George J. Schroepfer, Jr., and Ronald M. Evans

Evidence for two nonidentical drug-interaction 10594-10599 sites in the human P-glycoprotein

Saibal Dey, Muralidhara Ramachandra, Ira Pastan, Michael M. Gottesman, and Suresh V. Ambudkar

Terpenoid biosynthesis from 1-deoxy-D-xylulose 10600-10605 in higher plants by intramolecular skeletal rearrangement

Duilio Arigoni, Silvia Sagner, Christoph Latzel, Wolfgang Eisenreich, Adelbert Bacher, and Meinhart H. Zenk

Both DNA gyrase and reverse gyrase are present 10606-10611 in the hyperthermophilic bacterium Thermotoga maritima

Olivier Guipaud, Evelyne Marguet, Kenneth M. Noll, Claire Bouthier de la Tour, and Patrick Forterre

In vitro selection of self-cleaving RNAs with a low 10612-10617 pH optimum

Vineetha K. Jayasena and Larry Gold

A versatile synthetic dimerizer for the regulation of 10618-10623 protein-protein interactions

Jane F. Amara, Tim Clackson, Victor M. Rivera, Tao Guo, Terence Keenan, Sridaran Natesan, Roy Pollock, Wu Yang, Nancy L. Courage, Dennis A. Holt, and Michael Gilman

B cell receptor-associated protein a4 displays 10624-10629 rapamycin-sensitive binding directly to the catalytic subunit of protein phosphatase 2A

Kohei Murata, Jun Wu, and David L. Brautigan

BIOPHYSICS

Fluorescence and photobleaching dynamics of single 10630-10635 light-harvesting complexes

Martin A. Bopp, Yiwei Jia, Liangquan Li, Richard J. Cogdell, and Robin M. Hochstrasser

Protein folding kinetics exhibit an Arrhenius 10636-10640 temperature dependence when corrected for the temperature dependence of protein stability

Michelle L. Scalley and David Baker

Conformational fluctuations in single 10641-10646 DNA molecules

Stefan Wennmalm, Lars Edman, and Rudolf Rigler

iv

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Contents

Proteins unfold in steps 10647-10651 G. Zocchi

Characteristic temperatures of folding of a 10652-10656 small peptide

Ulrich H. E. Hansmann, Masato Masuya, and Yuko Okamoto

CELL BIOLOGY

Constitutive and impaired signaling of leptin 10657-10662 receptors containing the Gln -> Pro extracellular domain fatty mutation

David W. White, Yanping Wang, Streamson C. Chua, Jr., J. P. Morgenstern, Rudolph L. Leibel, Heinz Baumann, and Louis A. Tartaglia

Strain-specific differences in mouse hepatic wound 10663-10668 healing are mediated by divergent T helper cytokine responses

Zengdun Shi, Adil E. Wakil, and Don C. Rockey

Transforming growth factor ,8-induced 10669-10674 phosphorylation of Smad3 is required for growth inhibition and transcriptional induction in epithelial cells

Xuedong Liu, Yin Sun, Stefan N. Constantinescu, Edmund Karam, Robert A. Weinberg, and Harvey F. Lodish

Analysis of exocytosis mutants indicates 10675-10680 close coupling between regulated secretion and transcription activation in Tetrahymena

Alex Haddad and Aaron P. Turkewitz

Iron regulatory protein 1 is not required for the 10681-10686 modulation of ferritin and transferrin receptor expression by iron in a murine pro-B lymphocyte cell line

Kevin L. Schalinske, Kenneth P. Blemings, Daniel W. Steffen, Opal S. Chen, and Richard S. Eisenstein

Lack of cell cycle regulation of telomerase 10687-10692 activity in human cells

Shawn E. Holt, Dara L. Aisner, Jerry W. Shay, and Woodring E. Wright

Two sterol regulatory element-like sequences 10693-10698 mediate up-regulation of caveolin gene transcription in response to low density lipoprotein free cholesterol

Anita Bist, Phoebe E. Fielding, and Christopher J. Fielding

Hypo-phosphorylation of the retinoblastoma 10699-10704 protein (pRb) by cyclin D:Cdk4/6 complexes results in active pRb

Sergei A. Ezhevsky, Hikaru Nagahara, Adita M. Vocero-Akbani, David R. Gius, Michael C. Wei, and Steven F. Dowdy

Cell-cell interaction in prostate gene regulation 10705-10710 and cytodifferentiation

Alvin Y. Liu, Lawrence D. True, Leah LaTray, Peter S. Nelson, William J. Ellis, Robert L. Vessella, Paul H. Lange, Leroy Hood, and Ger van den Engh

Na,K-ATPase transport from endoplasmic 10711-10716 reticulum to Golgi requires the Golgi spectrin-ankyrin G119 skeleton in Madin Darby canine kidney cells

Prasad Devarajan, Paul R. Stabach, Maria Antonietta De Matteis, and Jon S. Morrow

CLARP, a death effector domain-containing 10717-10722 protein interacts with caspase-8 and regulates apoptosis

Naohiro Inohara, Takeyoshi Koseki, Yuanming Hu, Shu Chen, and Gabriel Nuinez

Nuclear localization signal binding protein from 10723-10728 Arabidopsis mediates nuclear import of Agrobacterium VirD2 protein

Nurit Ballas and Vitaly Citovsky

DEVELOPMENTAL BIOLOGY

Xenopus Cdc6 confers sperm binding competence 10729-10734 to oocytes without inducing their maturation

Jingdong Tian, Gerald H. Thomsen, Hui Gong, and William J. Lennarz

ECOLOGY

Experimental evidence for a behavior-mediated 10735-10738 trophic cascade in a terrestrial food chain

Andrew P. Beckerman, Maria Uriarte, and Oswald J. Schmitz

EVOLUTION

Intron "sliding" and the diversity of intron positions 10739-10744 Arlin Stoltzfus, John M. Logsdon, Jr., Jeffrey D. Palmer, and W. Ford Doolittle

Phylogenetic assessment of length variation at a 10745-10749 microsatellite locus

Guillermo Orti, Devon E. Pearse, and John C. Avise

The exaptive excellence of spandrels as a term 10750-10755 and prototype

Stephen Jay Gould

GENETICS

Fluorescence energy transfer detection as a 10756-10761 homogeneous DNA diagnostic method

Xiangning Chen, Barbara Zehnbauer, Andreas Gnirke, and Pui-Yan Kwok

Corepressor SMRT binds the BTB/POZ repressing 10762-10767 domain of the LAZ3/BCL6 oncoprotein

Philippe Dhordain, Olivier Albagli, Richard J. Lin, Stephane Ansieau, Sabine Quief, Achim Leutz, Jean-Pierre Kerckaert, Ronald M. Evans, and Dominique Leprince

Mitochondrial DNA rearrangements of Podospora 10768-10773 anserina are under the control of the nuclear gene grisea

Gonina Borghouts, Erik Kimpel, and Heinz D. Osiewacz

v

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Contents

Substrate specificity determinants in the 10774-10779 farnesyltransferase (3-subunit

Cynthia Evans Trueblood, Victor L. Boyartchuk, and Jasper Rine

The unique hetero-oligomeric nature of the 10780-10785 subunits in the catalytic cooperativity of the yeast Cct chaperonin complex

Paul Lin and Fred Sherman

The ARS309 chromosomal replicator of 10786-10791 Saccharomyces cerevisiae depends on an exceptional ARS consensus sequence

James F. Theis and Carol S. Newlon

Wolbachia, normally a symbiont of Drosophila, 10792-10796 can be virulent, causing degeneration and early death

Kyung-Tai Min and Seymour Benzer

Molecular cloning of a family of xenobiotic-inducible 10797-10802 drosophilid cytochrome P450s: Evidence for involvement in host-plant allelochemical resistance

Phillip B. Danielson, Ross J. Maclntyre, and James C. Fogleman

Noninfectious virus-like particles produced by 10803-10808 Moloney murine leukemia virus-based retrovirus packaging cells deficient in viral envelope become infectious in the presence of lipofection reagents

Sanjai Sharma, Fukashi Murai, Atsushi Miyanohara, and Theodore Friedmann

Genetic basis of tolerance to 02 deprivation in 10809-10812 Drosophila melanogaster

Gabriel G. Haddad, Yi-an Sun, Robert J. Wyman, and Tian Xu

Induction of minisatellite mutation in NIH 3T3 10813-10816 cells by treatment with the tumor promoter okadaic acid

Hitoshi Nakagama, Shigeto Kaneko, Hiroshi Shima, Hideaki Inamori, Hirokazu Fukuda, Ryo Kominami, Takashi Sugimura, and Minako Nagao

Minisatellite instability in severe combined 10817-10820 immunodeficiency mouse cells

Hiroshi Imai, Hitoshi Nakagama, Kenshi Komatsu, Taizo Shiraishi, Hirokazu Fukuda, Takashi Sugimura, and Minako Nagao

IMMUNOLOGY

Copolymer 1 induces T cells of the T helper 10821-10826 type 2 that crossreact with myelin basic protein and suppress experimental autoimmune encephalomyelitis

Rina Aharoni, Dvora Teitelbaum, Michael Sela, and Ruth Arnon

Telomere lengthening and telomerase activation 10827-10832 during human B cell differentiation

Nan-ping Weng, Lawrence Granger, and Richard J. Hodes

Immunostimulatory oligodeoxynucleotides 10833-10837 containing the CpG motif are effective as immune adjuvants in tumor antigen immunization

George J. Weiner, Hsin-Ming Liu, James E. Wooldridge, Christopher E. Dahle, and Arthur M. Krieg

An interleukin 4 (IL-4)-independent pathway for 10838-10843 CD4+ T cell IL-4 production is revealed in IL-4 receptor-deficient mice

Nancy Noben-Trauth, Leonard D. Shultz, Frank Brombacher, Joseph F. Urban, Jr., Hua Gu, and William E. Paul

Impaired CD19 expression and signaling, enhanced 10844-10849 antibody response to type II T independent antigen and reduction of B-1 cells in CD81-deficient mice

Erdyni N. Tsitsikov, Jose Carlos Gutierrez-Ramos, and Raif S. Geha

Two distinct proteolytic processes in the 10850-10855 generation of a major histocompatibility complex class I-presented peptide

Abie Craiu, Tatos Akopian, Alfred Goldberg, and Kenneth L. Rock

Enhanced immunogenicity of HIV-1 vaccine 10856-10861 construct by modification of the native peptide sequence

Jeffrey D. Ahlers, Toshiyuki Takeshita, C. David Pendleton, and Jay A. Berzofsky

MEDICAL SCIENCES

Tertiary hypothyroidism and hyperglycemia in mice 10862-10867 with targeted disruption of the thyrotropin-releasing hormone gene

Masanobu Yamada, Yumiko Saga, Nobuyuki Shibusawa, Jyunko Hirato, Masami Murakami, Toshiharu Iwasaki, Koshi Hashimoto, Teturou Satoh, Katsumi Wakabayashi, Makoto M. Taketo, and Masatomo Mori

The mechanism of cancer-mediated conversion of 10868-10872 plasminogen to the angiogenesis inhibitor angiostatin

Stephen Gately, Przemyslaw Twardowski, M. Sharon Stack, Deborah L. Cundiff, Davida Grella, Francis J. Castellino, Jan Enghild, Hau C. Kwaan, Francis Lee, Robert A. Kramer, Olga Volpert, Noel Bouck, and Gerald A. Soff

Immunologic tolerance to myelin basic protein 10873-10878 decreases stroke size after transient focal cerebral ischemia

Kyra J. Becker, Richard M. McCarron, Christl Ruetzler, Olgica Laban, Esther Sternberg, Kathleen C. Flanders, and John M. Hallenbeck

Role of tyrosine phosphorylation of a cellular protein 10879-10884 in adeno-associated virus 2-mediated transgene expression

Keyun Qing, Xu-Shan Wang, Dagmar M. Kube, Selvarangan Ponnazhagan, Anil Bajpai, and Arun Srivastava

Oncogenic transformation induced by the 10885-10888 Qin protein is correlated with transcriptional repression

Jian Li, Holger Thurm, Hwai Wen Chang, Jason S. Jacovoni, and Peter K. Vogt

vi

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Contents Interleukin 12 and B7-1 costimulatory molecule 10889-10894 expressed by an adenovirus vector act synergistically to facilitate tumor regression

Brigitte M. Piitzer, Mary Hitt, William J. Muller, Peter Emtage, Jack Gauldie, and Frank L. Graham

Somatic mutations in the p53 tumor suppressor gene 10895-10900 in rheumatoid arthritis synovium

Gary S. Firestein, Fernando Echeverri, Michele Yeo, Nathan J. Zvaifler, and Douglas R. Green

Cell death induction by the acute promyelocytic 10901-10906 leukemia-specific PML/RARa fusion protein

Pier Francesco Ferrucci, Francesco Grignani, Mark Pearson, Marta Fagioli, Ildo Nicoletti, and Pier Giuseppe Pelicci

Association of arsenic-induced malignant 10907-10912 transformation with DNA hypomethylation and aberrant gene expression

Christopher Q. Zhao, Matthew R. Young, Bhalchandra A. Diwan, Timothy P. Coogan, and Michael P. Waalkes

A single in vivo administration of bombesin 10913-10918 antagonist RC-3095 reduces the levels and mRNA expression of epidermal growth factor receptors in MXT mouse mammary cancers

Karoly Szepeshazi, Andrew V. Schally, Gabor Halmos, Najib Lamharzi, Kate Groot, and Judit E. Horvath

Heme oxygenase 1 is required for 10919-10924 mammalian iron reutilization

Kenneth D. Poss and Susumu Tonegawa

Reduced stress defense in heme oxygenase 10925-10930 1-deficient cells

Kenneth D. Poss and Susumu Tonegawa

Transformation with human dihydrofolate reductase 10931-10936 renders malaria parasites insensitive to WR99210 but does not affect the intrinsic activity of proguanil

David A. Fidock and Thomas E. Wellems

Molecular origin of cancer: Catechol 10937-10942 estrogen-3,4-quinones as endogenous tumor initiators

E. L. Cavalieri, D. E. Stack, P. D. Devanesan, R. Todorovic, I. Dwivedy, S. Higginbotham, S. L. Johansson, K. D. Patil, M. L. Gross, J. K. Gooden, R. Ramanathan, R. L. Cerny, and E. G. Rogan

MICROBIOLOGY

Transfer of the HIV-1 cyclophilin-binding site to 10943-10948 simian immunodeficiency virus from Macaca mulatta can confer both cyclosporin sensitivity and cyclosporin dependence

Anatoly A. Bukovsky, Andreas Weimann, Molly A. Accola, and Heinrich G. G6ttlinger

Minimum size limit for useful locomotion by 10949-10954 free-swimming microbes

David B. Dusenbery

Efficient allelic exchange and transposon 10955-10960 mutagenesis in Mycobacterium tuberculosis

Vladimir Pelicic, Mary Jackson, Jean-Marc Reyrat, William R. Jacobs, Jr., Brigitte Gicquel, and Christophe Guilhot

Conditionally replicating mycobacteriophages: 10961-10966 A system for transposon delivery to Mycobacterium tuberculosis

Stoyan Bardarov, Jordan Kriakov, Christian Carriere, Shengwei Yu, Carlos Vaamonde, Ruth A. McAdam, Barry R. Bloom, Graham F. Hatfull, and William R. Jacobs, Jr.

Expression of a gene encoding a 16.9-kDa heat-shock 10967-10972 protein, Oshspl6.9, in Escherichia coli enhances thermotolerance

Ching-Hui Yeh, Pi-Fang Linda Chang, Kai-Wun Yeh, Wan-Chi Lin, Yih-Ming Chen, and Chu-Yung Lin

An opsonic function of the neutrophil 10973-10978 bactericidal/permeability-increasing protein depends on both its N- and C-terminal domains

Nicole M. lovine, Peter Elsbach, and Jerrold Weiss

NEUROBIOLOGY

Blind separation of auditory event-related brain 10979-10984 responses into independent components

Scott Makeig, Tzyy-Ping Jung, Anthony J. Bell, Dara Ghahremani, and Terrence J. Sejnowski

Induction of inhibitory factor KBa mRNA in the 10985-10990 central nervous system after peripheral lipopolysaccharide administration: An in situ hybridization histochemistry study in the rat

Ning Quan, Michael Whiteside, Leopold Kim, and Miles Herkenham

Prospero is a panneural transcription factor that 10991-10996 modulates homeodomain protein activity

Bassem Hassan, Ling Li, Kirsten A. Bremer, Weiru Chang, Julia Pinsonneault, and Harald Vaessin

The selectivity of the hair cell's mechanoelectrical- 10997-11002 transduction channel promotes Ca21 flux at low Ca2+ concentrations

Ellen A. Lumpkin, Robert E. Marquis, and A. J. Hudspeth

Maintenance of a somatotopic cortical map in the 11003-11007 face of diminishing thalamocortical inputs

E. G. Jones, P. R. Manger, and T. M. Woods

Responses in the brain of estrogen receptor 11008-11012 a-disrupted mice

Paul J. Shughrue, Dennis B. Lubahn, Andres Negro-Vilar, Kenneth S. Korach, and Istvan Merchenthaler

hSK4, a member of a novel subfamily of 11013-11018 calcium-activated potassium channels

William J. Joiner, Lu-Yang Wang, Michael D. Tang, and Leonard K. Kaczmarek

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Contents

Functional consequences of NR2 subunit 11019-11024 composition in single recombinant N-methyl-D-aspartate receptors

Jessica C. Brimecombe, Faye A. Boeckman, and Elias Aizenman

Site-specific, photochemical proteolysis applied to 11025-11030 ion channels in vivo

Pamela M. England, Henry A. Lester, Norman Davidson, and Dennis A. Dougherty

PHARMACOLOGY

The interaction of the general anesthetic etomidate 11031-11036 with the y-aminobutyric acid type A receptor is influenced by a single amino acid

Delia Belelli, Jeremy J. Lambert, John A. Peters, Keith Wafford, and Paul J. Whiting

p53-dependent regulation of MDR1 gene expression 11037-11042 causes selective resistance to chemotherapeutic agents

Jaideep V. Thottassery, Gerard P. Zambetti, Kazuhiko Arimori, Erin G. Schuetz, and John D. Schuetz

Inter- and intraspecies polymorphisms in the 11043-11048 cholecystokinin-B/gastrin receptor alter drug efficacy

Alan S. Kopin, Edward W. McBride, Michelle C. Gordon, Suzanne M. Quinn, and Martin Beinborn

PHYSIOLOGY

Nitric oxide in the contractile action of bradykinin, 11049-11054 oxytocin, and prostaglandin F2 a in the estrogenized rat uterus

M. Chaud, A. M. Franchi, V. Rettori, S. M. McCann, and M. F. Gimeno

Protein phosphatase 2C dephosphorylates and 11055-11060 inactivates cystic fibrosis transmembrane conductance regulator

Sue M. Travis, Herbert A. Berger, and Michael J. Welsh

Voltage dependence of the pattern and frequency 11061-11066 of discrete Ca2+ release events after brief repriming in frog skeletal muscle

Michael G. Klein, Alain Lacampagne, and Martin F. Schneider

AUTHOR INDEX

INFORMATION FOR AUTHORS

SIZING WORKSHEET

COPYRIGHT ASSIGNMENT FORM

Type II regulatory subunits are not required for the 11067-11072 anchoring-dependent modulation of Ca2+ channel activity by cAMP-dependent protein kinase

Kimberly A. Burton, Barry D. Johnson, Zachary E. Hausken, Ruth E. Westenbroek, Rejean L. Idzerda, Todd Scheuer, John D. Scott, William A. Catterall, and G. Stanley McKnight

Leptin and leptin receptor mRNA and protein 11073-11078 expression in the murine fetus and placenta

Nigel Hoggard, Leif Hunter, Jacqueline S. Duncan, Lynda M. Williams, Paul Trayhurn, and Julian G. Mercer

PLANT BIOLOGY

Molecular and functional characterization of a 11079-11084 novel low-affinity cation transporter (LCT1) in higher plants

Daniel P. Schachtman, Raman Kumar, Julian I. Schroeder, and Ellen L. Marsh

Myelin basic protein kinase activity in tomato 11085-11089 leaves is induced systemically by wounding and increases in response to systemin and oligosaccharide elicitors

Johannes W. Stratmann and Clarence A. Ryan

Cell type-specific loss of atp6 RNA editing in 11090-11095 cytoplasmic male sterile Sorghum bicolor

Werner Howad and Frank Kempken

Link between light and fatty acid synthesis: 11096-11101 Thioredoxin-linked reductive activation of plastidic acetyl-CoA carboxylase

Yukiko Sasaki, Akiko Kozaki, and Mika Hatano

Regulation of sulfur assimilation in higher plants: 11102-11107 A sulfate transporter induced in sulfate-starved roots plays a central role in Arabidopsis thaliana

Hideki Takahashi, Mami Yamazaki, Noriko Sasakura, Akiko Watanabe, Thomas Leustek, Janice de Almeida Engler, Gilbert Engler, Marc Van Montagu, and Kazuki Saito

CORRECTION

PHYSIOLOGY Role of leptin in hypothalamic-pituitary function 11108

W. H. Yu, M. Kimura, A. Walczewska, S. Karanth, and S. M. McCann

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