Front Matter Source: Proceedings of the National Academy of Sciences of the United States of America, Vol. 74, No. 7 (Jul., 1977), pp. v-x Published by: National Academy of Sciences Stable URL: http://www.jstor.org/stable/67198 . Accessed: 07/05/2014 20:13 Your use of the JSTOR archive indicates your acceptance of the Terms & Conditions of Use, available at . http://www.jstor.org/page/info/about/policies/terms.jsp . JSTOR is a not-for-profit service that helps scholars, researchers, and students discover, use, and build upon a wide range of content in a trusted digital archive. We use information technology and tools to increase productivity and facilitate new forms of scholarship. For more information about JSTOR, please contact [email protected]. . National Academy of Sciences is collaborating with JSTOR to digitize, preserve and extend access to Proceedings of the National Academy of Sciences of the United States of America. http://www.jstor.org This content downloaded from 169.229.32.136 on Wed, 7 May 2014 20:13:47 PM All use subject to JSTOR Terms and Conditions
Transcript
Front MatterSource: Proceedings of the National Academy of Sciences of the United States of America,Vol. 74, No. 7 (Jul., 1977), pp. v-xPublished by: National Academy of SciencesStable URL: http://www.jstor.org/stable/67198 .
Accessed: 07/05/2014 20:13
Your use of the JSTOR archive indicates your acceptance of the Terms & Conditions of Use, available at .http://www.jstor.org/page/info/about/policies/terms.jsp
.JSTOR is a not-for-profit service that helps scholars, researchers, and students discover, use, and build upon a wide range ofcontent in a trusted digital archive. We use information technology and tools to increase productivity and facilitate new formsof scholarship. For more information about JSTOR, please contact [email protected].
.
National Academy of Sciences is collaborating with JSTOR to digitize, preserve and extend access toProceedings of the National Academy of Sciences of the United States of America.
http://www.jstor.org
This content downloaded from 169.229.32.136 on Wed, 7 May 2014 20:13:47 PMAll use subject to JSTOR Terms and Conditions
National Academy of Sciences OF THE UNITED STATES OF AMERICA
Officers PHILIP HANDLER President of the SAUNDERS MAC LANE Vice President Academy DAVID R. GODDARD Home Secretary
GEORGE S. HAMMOND Foreign Secretary E. R. PIORE Treasurer
Editorial Board ROBERT L. SINSHEIMER Chairman of the ROBERT M. SOLOW Vice Chairman Proceedings HARRISON SHULL Vice Chairman
DAVID R. GODDARD Home Secretary GEORGE S. HAMMOND Foreign Secretary E. R. PIORE Treasurer
ALEXANDER G. BEARN S. M. LIPSET P. D. BOYER MACLYN MCCARTY HARRY EAGLE EUGENE P. ODUM HERMAN EISEN ALEXANDER RICH RICHARD M. HELD E. R. STADTMAN MARTIN D. KAMEN ELIAS M. STEIN HENRY S. KAPLAN HOWARD M. TEMIN SEYMOUR S. KETY JAMES TOBIN
Managing Editor: BERNARD K. FORSCHER Associate Managing Editor: FRANKLIN H. PORTUGAL Assistant Managing Editor: GARY T. COCKS Adjunct Associate Managing Editor: MURRIE W. BURGAN
Editorial correspondence: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, 2101 Constitution Avenue, Washington, D.C. 20418.
Business correspondence: Circulation Office of the PROCEEDINGS, National Academy of Sciences, 2101 Constitution Avenue, Washington, D.C. 20418. (For Member's subscriptions, see below.)
Subscriptions: Members of the National Academy of Sciences should address all correspondence concerning their sub- scriptions to the Home Secretary's Office.
Other subscribers should address all correspondence concerning subscriptions to the Circulation Office of the Proceedings. Subscriptions are entered on a calendar-year basis only. The 1977 subscription rate is $55. Subscribers are requested to notify the Circulation Office of the Proceedings 6 weeks in advance of any change of address; also the local postmaster. The Academy is not responsible for nonreceipt of issues because of improper address unless a change of address is on file. The notice of address change should list both the old and new addresses. Claims for replacement copies will not be honored more than 60 days after the mailing date for domestic subscribers and not more than 90 days after the mailing date for foreign subscribers.
Back Issues (Volumes 1-68, through December 1971) are available from Walter J. Johnson, Inc., 355 Chestnut Street, Norwood, N.J. 07648. Prices are available from that organization upon request. Back Issues (Volumes 69-73, January 1972 and thereafter) are available from the Circulation Office of the Proceedings. The price of a single issue is $5.50.
Microfilms of complete volumes are available to regular subscribers only and may be obtained from University Microfilms, Xerox Corporation, Ann Arbor, Michigan 48103.
frtecond c la.ss po*stage paid at Washington, D.C. anDd at addi tional mailin,g offices PRINTED IN THE UJSA
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA is published monthly by THE NATIONALJ ACADEMY OF SCIENCES, 2101 Constitution Avenue, Washington, D.C. 20418
This content downloaded from 169.229.32.136 on Wed, 7 May 2014 20:13:47 PMAll use subject to JSTOR Terms and Conditions
Aaronson, S. A. 2953 Abe, M. 2756 Adar, F. 2607 Agarwal, R. C. 2835 Aharonov, A. 2790 Ahrens, E. H., Jr. 3043 Allet, B. 3104 Andres, R. Y. 2785 Andrew, S. L. 2989 Athwal, R. S. 2943 Atiyah, M. F. 2662 August, J. T. 2729 Ausubel, F. M. 2963 Balmas, K. 3095 Barak, L. S. 2909 Barratt, D. G. 2751 Ben-Ari, Y. 3078 Bender, M. L. 2634 Bennett, V. 2860 Berg, H. C. 3060 Bevan, S. 3090 Bhatia, B. 3095 Bieber, L. L. 2795 Bina-Stein, M. 2780 Binns, A. 2928 Bishop, J. M. 2879 Blanchard, M. H. 2672 Blazej, D. C. 2639 Bono, V. H., Jr. 2889 Boyd, D. H. 2756 Bradshaw, R. A. 2785 Brice, M. 2923 Browder, F. E. 2659 Brown, C. 2756 Brown, M. 2874 Burton, W. G. 2687 Butchko, G. M. 3006 Butow, R. A. 2715 Cabradilla, C. D. 2953 Cannon, F. C. 2963 Canuel, L. L. 2624 Carey, C. 3095 Cedar, H. 2725 Champion, M. J. 2968 Chang, J. C. 3047 Chang, R. L. 2746 Cheeger, J. 2651 Chern, C. J. 2948 Chock, P. B. 2761, 2766 Choi, H.-S. 3033 Choi, Y. R. 2795 Clifford, P. 2756 Cohen, A. M. 2899 Conlon, S. 3019 Conn, J. F. 2655 Conney, A. H. 2746 Cosand, W. L. 2771 Cote, R. H. 2756 Croce, C. M. 2985 Crouse, J. R. 3043 Cuatrecasas, P. 2860 Das, M. 2790 Davis, B. D. 2830 Destree, A. 2855 de Zoeten, G. A. 2919 Diaconescu, C. 2697 Diamond, L. 2894 Dixon, G. H. 2810 Domnina, L. V. 2865 Dreyfus, C. F. 3086 Duesler, E. 2602 Dunham, P. B. 3099 Eipper, B. A. 3014 Eisen, H. 3104
Elde, R. 3081 Elson, E. L. 2909 Emmett, W. W. 2644 Ennis, F. A. 3006 Erdmann, V. A. 2706 Eventoff, W. 2677 Eyring, H. 2598 Fernandez-J'ol, J. A. 2889 Finn, F. M. 2697 Fox, C. F. 2790 Freeman, M. J. 3011 Friedman, J. M. 2607 Friesen, H.-J. 2697 Gelfand, I. M. 2865 Gerber, L. 1). 3052 Gerhard, W. 2985 Gershon, M. D. 3086 Gitel, S. N. 3028 Glass, J. 2739 Golubovsky, M. D. 2973 Good, R. A. 3002 Goto, T. 2799 Grant, C. W. M. 2751 Green, M. M. 2973 Hakomori, S. 3023 Hall, T. C. 2682 Hammes, (G. G. 2909 Harold, F. M. 3060 Hartley, J. W. 3065 Hashimoto, J. 2734 Hata, R.-I. 2933 Hayakawa, H. 2958 Heinemann, S. 3090 Hendrickson, W. G. 2756 Herrera, I. 2595 Herschman, H. R. 2790 Hirota, Y. 2976 Hitchin, N. J. 2662 Hodgkin, J. 2938 Hofmann, K. 2697 Hokfelt, T. 3081 Hollenberg, M. D. 2860 Holsters, M. 2848 Horecker, B. L. 2742 Hu, W. W. L. 2904 Hynes, R. 0. 2855 Ikemura, P. 2710 Incefy, G. S. 3002 Isaacs, N. W. 2835 Ivanov, Yui. N. 2973 Iwaya, M. 2980 Jeng, I. 2785 Jerina, D. M. 2746 Joh, T. H. 3086 Johnson, F. H. 2799 Johnson, G. S. 2889 Jordan, S. R. 2820 Kacian, D. L. 2840 Kaiser, D. 2938 Kan, Y. W. 3047 Karle, I. L. 2602 Karle, J. M. 2746 Keenan, T. W. 3011 Keil, W. 2677 Keppel, F. 3104 Kiehn, D. 2874 Kiltz, H.-H. 2677 Kloppel, 'r. M. 3011 Knight, B. W. 3068 Kodama, Y. 2734 Kohl, R. .J. 2682 Komiyama, M. 2634 Kopelovich, L. 3019 Koprowski, H. 2985
Kosower, E. M. 2884 Kosower, N. S. 2884 Kullberg, R. 3090 Lai, T. L. 2667 Law, S. K. 2701 Lee, S. T. 2598 Legon, S. 2692 Lehr, R. E. 2746 Leopold, L. B. 2644 Levin, W. 2746 Levine, R. P. 2701 Levings, C. S., III 2904 Levitan, H. 2914 Levy W, B. 2810 Lindstrom, J. 3090 Ling, N. 3014 Ljungdahl, A. 3081 Lustig, S. 2884 Ma, S.-M. 2598 McBride, 0. W. 2943 Machida, Y. 2776 McKimm, J. 3056 McMahan, U. J. 3073 McNamara, D. J. 3043 Mains, R. E. 3014 Manson, M. D. 3060 Marsh, R. C. 2720 Marshall, L. M. 3073 Martiin, W. J. 3006 Maruyama, I. N. 2976 Matsuhashi, M. 2976 Meins, F., Jr. 2928 Merrif'ield, R. B. 2771 Merrif'ield, R. E. 2616 Metzger, H. 2993 Meyer, H. 2677 Miller, M. D. 2820 Miura, K.-I. 2734 Miyakawa, T. 2790 Model, P. 2692 Morgan, E. A. 2710 Morre, D. J. 3011 Muller, J. E. 3033, 3035 Murphy, R. A. 2672 Myers, J. C. 2840 Myers, P. A. 2687 Nagasawa, S. 2998 Nilsson, G. 3081 Nishimura, Y. 2976 Nomura, M. 2710 Novikoff, P. M. 3038 O'Brien, T. G. 2894 Ogino, U. 2976 Okada, Y. 2958 Okazaki, R. 2776 Okazaki, T. 2776 O'Reilly, R. J. 3002 Paganelli, C. 3095 Pahwa, R. 3002 Pahwa, S. 3002 Papayannopoulou, T. 2923 Paronetto, F. 3033 Pastan, I. 2909 Patel, D. J. 2624 Pauling, L. 2612, 2614 Pedrosa, F. 0. 2742 Pelzig, M. 2739 Peterkofsky, B. 2933 Peticolas, W. L. 2639 Petit, A. 2848 Philo, J. S. 2620 Pickel, V. M. 3086 Pincus, M. R. 2629 Pinon, R. 2850
v
This content downloaded from 169.229.32.136 on Wed, 7 May 2014 20:13:47 PMAll use subject to JSTOR Terms and Conditions
Pletyushkina, 0. Y. 2865 Pluznik, D. H. 2884 Pollack, R. 3019 Pontremoli, S. 2742 Powell, C. A. 2919 Pring, D. R. 2904 Pruss, R. M. 2790 Rahn, H. 3095 Rao, P. N. 2869 Rapp, F. 3056 Razin, A. 2725 Reinisch, C. L. 2989 Reis, I). J. 3086 Reynolds, J. A. 2803 Rice, J. 3090 Riedel, G. E. 2963 Ringold, G. M. 2879 Robbins, H. 2667, 2670 Robbins, K. C. 2953 Roberts, R. J. 2687 Robertson, H. D. 2692 Rossmann, M. G. 2677 Rousseau, D. L. 2607 Rovera, G. 2894 Rowe, W. P. 3065 Rubinstein, M. 3052 Sager, R. 2687 Sahyoun, N. 2860 Saide, J. D. 2672 Salemme, F. R. 2820 Salts, Y. 2850 Samuel, P. 3043 Sanes, J. R. 3073 Schaechter, M. 2756 Schaefer-Ridder, M. 2746 Schell, J. 2848 Scheraga, H. A. 2629 Schlessinger, J. 2909
Schlossman, S. F. 2989 Segal, D. M. 2993 Sekiguchi, M. 2958 Senyk, 0. 3099 Shapley, R. M. 3068 Sharom, F. J. 2751 Shimomura, 0. 2799 Shimotohno, K. 2734 Shows, T. B. 2968 Silverman, M. 2825 Simmons, H. E. 2616 Simpson, R. T. 2780 Singer, I. M. 2662 Smith, W. P'. 2830 Spiegelman, S. 2840 Staal, S. P. 3065 Stadtman, E. R. 2761, 2766 Stamatoyannopoulos, G. 2923 Stein, A. 2780 Stein, S. 3052 Stephenson, J. R. 2953 Stephenson, R. C. 3028 Stoeckenius, W. 2803 Strand, M. 2729 Straus, E. 3033, 3035 Strausberg, R. L. 2715 Strominger, J. L. 2980 Stroud, R. M. 2998 Sunkara, P. 5. 2869 Suzuki, H. 2976 Szent-Gyorgyi, A. 2844 'I'ai, P.-C. 2830 'I'akagaki, Y. 2976 'I'akeda, A. 2634 'I'amaki, 5. 2976 'I'an, K. B. 2805 'I'anaka, K. 2958 'I'aurog, J. D. 2993
'I'aylor, S. S. 2677 Tedesco, P. 3060 'I'eller, E. 2664 'I'empe, J. 2848 'I'emple, G. F. 3047 'I'erenius, L. 3081 'I'hompson, R. C. 2830 'I'imothy, D. H. 2904 'I'orff, H.-J. 2677 'I'urner, R. J. 2825 Udenfriend, S. 3052 Utaka, M. 2634 van der Drift, C. 3060 van Montagu, M. 2848 Varmus, H. E. 2879 Vasiliev, J. M. 2865 Verbonitz, M. W. 3006 Victor, J. D. 3068 Vogan, D. A., Jr. 2649 Wang, S.-M. 3023 Webb, W. W. 2909 Wessler, S. 3028 Wickner, S. 2815 Wilson, B. A. 2869 Wong, N. C. W. 2810 Wood, A. W. 2746 Worcel, A. 2720 Wrede, P. 2706 Yalow, R. S. 3033, 3035 Yamada, K. M. 2909 Yamamoto, K. R. 2879 Yoon, Y. H. 2598 Young, M. 2672 Young, W. W., Jr. 3023 Zahn, H. 2697 Zigmond, R. E. 3078 Zimmerman, S. S. 2629
vi
This content downloaded from 169.229.32.136 on Wed, 7 May 2014 20:13:47 PMAll use subject to JSTOR Terms and Conditions
PHYSIOLOGICAL Modulation of acetylcholine receptor by antibody against the receptor (muscle/acetylcholine sensitivityl SCIENCES acetylcholine noise/myasthenia gravis).
.S..Heinemann,.S..Bevan,.R..K.llberg, J. Lindstrom, and J. Rice 3090-3094 Reduction of pore area of the avian eggshell as an adaptation to altitude (water vapor permeability) ......
........................................ .H. Rahn, C. Carey, K. Balmas, B. Bhatia, and C. Paganelli 3095-3098 Lithium efflux through the Na/K pump in human erythrocytes (cation transport/erythrocyte membranes/manic
depression) .................................. Philip B. Dunham and Oksana Senyk 3099-3103
Correction
CELL BIOLOGY Appearance of a chromatin protein during the erythroid differentiation of Friend virus-transformed cells (nonhistone proteins/dimethyl sulfoxide/erythroleukemia cells/histones).. ................................................ .France Keppel, Bernard Allet, and Harvey Eisen 3104
.i.
This content downloaded from 169.229.32.136 on Wed, 7 May 2014 20:13:47 PMAll use subject to JSTOR Terms and Conditions
Dimeric immunoglobulin E serves as a unit signal for mast cell degranulation (histamine release/exocytosisl crosslinking reagent/Fc receptor) ............... David M. Segal, Joel D. Taurog, and Henry Metzger 2993-2997
Cleavage of C2 by Cls into the antigenically distinct fragments C2a and C2b: Demonstration of binding of C2b to C4b (complement/classical C3 convertase/enzyme activation) ..............................
.................................................... Shigeharu Nagasawa and Robert M2. Stroud 2998-3001 Rationale for combined use of fetal liver and thymus for immunological reconstitution in patients with variants
of severe combined immunodeficiency (lymphoid differentiation/embryology/transplantation/thymic epithelium/chim erism ) ......................................................................
........ .Rajendra Pahwa, Savita Pahwa, Robert A. Good, Genevieve S. Incefy, and Richard J. O'Reilly 3002-3005 Specificity studies on cytotoxic thymus-derived lymphocytes reactive with influenza virus-infected cells:
Evidence for dual recognition of H-2 and viral hemagglutinin antigens (major histocompatibility complex! viral immunity/T cell killing) ................................................................ . ................. Francis A. Ennis, W. John Martin, Martha W. Verbonitz, and Gregory M. Butchko 3006-3010
MEDICAL Glycolipid-bound sialic acid in serum: Increased levels in mice and humans bearing mammary carcinomas SCIENCES (ganglioside/blood/cancer/cancer detection).
. ................... Thomas M. Kloppel, Thomas W. Keenan, Max J. Freeman, and D. James Morre' 3011-3013 Common precursor to corticotropins and endorphins (pituitary tumor cells/I-lipotropin/I-melanotropin/
peptide analysis/immunoprecipitation) ........ Richard E. Mains, Betty A. Eipper, and Nicholas Ling 3014-3018 Defective organization of actin in cultured skin fibroblasts from patients with inherited adenocarcinoma (ad-
enomatosis of colon and rectum/cytoskeleton/cancer detection/immunofluorescence/inherited disease) . ............................... ............ Levy Kopelovich, Susan Conlon, and Robert Pollack 3019-3022
Isoantigenic expression of Forssman glycolipid in human gastric and colonic mucosa: Its possible identity with "A-like antigen" in human cancer (Forssman-positive and Forssman-negative populations/tumor! globoside/blood group) ............................ S. Hakomori, S.-M. Wang, and W. W. Young, Jr. 3023-3027
In vitro and in vivo correlation of clotting protease activity: Effect of heparin (coagulation/antithrombin III/animal model) ........... Sanford N. Gitel, Ronald C. Stephenson, and Stanford Wessler 3028-3032
Immunohistochemical localization in rabbit brain of a peptide resembling the COOH-terminal octapeptide of cholecystokinin (neuropeptides/gastrointestinal-like peptide/antibody specificity/cortical neurons) .......... Eugene Straus, Jurgen E. Muller, Ho-Soon Choi, Fiorenzo Paronetto, and Rosalyn S. Yalow 3033-3034
Cholecystokinin and its COOH-terminal octapeptide in the pig brain (neuropeptides/radioimmunoassay/size and charge discrimination/antibody specificity/gastrointestinal-like peptide) ......................
......................................... .Jurgen E. Muller, Eugene Straus, and Rosalyn S. Yalow 3035-3037 Fatty liver induced in Zucker "fatty" (ff) rats by a semisynthetic diet rich in sucrose (hyperlipidemia/obe-
sity/congenital disorders/Golgi apparatus/GERL) ............................. Phyllis M. Novikoff 3038-3042 Measurement of daily cholesterol synthesis rates in inan by assay of the fractional conversion of mevalonic
acid to cholesterol (sterol balance/squalene kinetics/cholesterol kinetics/input-output analysis/isotope ratio) .... Donald J. McNamara, E. H. Ahrens, Jr., Paul Samuel, and John R. Crouse 3043-3046
Authentic ,B-globin mRNA sequences in homozygous 30-thalassemia (cDNA/hybridization/nucleotide se- quences) ....G ary F. Temple, Judy C. Chang, and Yuet Wai Kan 3047-3051
Isolation and characterization of the opioid peptides from rat pituitary: f-Lipotropin (fluorescence analy- sis/high performance liquid chromatography) .................................................. ......................................... .M. Rubinstein, S. Stein, L. D. Gerber, and S. Udenfriend 3052-3055
MICROBIOLOGY Variation in ability of measles virus plaque progeny to induce interferon (genetics/paramyxovirus/induction) . ........................................................... Jennifer McKimm and Fred Rapp 3056-3059
A protonmotive force drives bacterial flagella (bacterial motility/ionophores/fluorescent dyes) .......... ....... .Michael D. Manson, Pat Tedesco, Howard C. Berg, Franklin M. Harold, and Chris van der Drift 3060-3064
Isolation of transforming murine leukemia viruses from mice with a high incidence of spontaneous lymphoma (AKR mice/Akv-2 congenic/nonproducer cell line/pseudotype) ................................... . ....................................... Stephen P. Staal, Janet W. Hartley, and Wallace P. Rowe 3065-3067
NEUROBIOLOGY Nonlinear analysis of cat retinal ganglion cells in the frequency domain (neural networks/vision) ......... . ................................... Jonathan D. Victor, Robert M. Shapley, and Bruce W. Knight 3068-3072
Reinnervation of original synaptic sites on muscle fiber basement membrane after disruption of the muscle cells (neuromuscular junction/topographic specificity/regeneration/denervation/synaptogenesis). . ..................................... Lawrence M. Marshall, Joshua R. Sanes, and U. J. McMahan 3073-3077
Electrical stimulation of preganglionic nerve increases tyrosine hydroxylase activity in sympathetic ganglia (tyrosine 3-monooxygenase/superior cervical gang,lion) . . . ................. Richard E. Zigmond and Yehezkel Bien-Ani................ 3078-3080
Immunohistochemical analysis of peptide pathways possibly related to pain and analgesia: Enkephalin and substance P (spinal interneurons/descending spinal systems/primary afferents)........... ....................Tomas H6k felt, Ake Ljungdahl, Lars Terenius, Robert Elde, and Go3ran Nilsson ............................. 3081-3085
Serotonergic neurons in the peripheral nervous system: Identification in gut by immunohistochemical local- ization of tryptophan hydroxylase (myenteric plexus/serotonin/monoamines/tissue culture/neuro- transmission) ........M. D. Gershon, C. F. Dreyf us, V. M. Pickel, T. H. Joh, and D. J. Reis ............................. 3086-3089
(Continued on page vii) viii
This content downloaded from 169.229.32.136 on Wed, 7 May 2014 20:13:47 PMAll use subject to JSTOR Terms and Conditions
Tumor promoters inhibit spontaneous differentiation of Friend erythroleukemia cells in culture (phorbol diesters/terminal differentiation/hemoglobin subunits/mouse erythroleukemia) .................... ........................................ .Giovanni Rovera, Thomas G. O'Brien, and Leila Diamond 2894-2898
Independent expression of the adrenergic phenotype by neural crest cells in vitro (differentiation/catechol- amines/sympathetic neurons/neurogenesis) .................................. Alan M. Cohen 2899-2903
Unique DNA associated with mitochondria in the "S"-type cytoplasm of male-sterile maize (episomal DNA! plasmid DNA/cytoplasmic inheritance) ....................................................... ...................................D. R. Pring, C. S. Levings, III, W. W. L. Hu, and D. H. Timothy 2904-2908
Mobility and distribution of a cell surface glycoprotein and its interaction with other membrane components (membrane-associated glycoprotein/cell adhesion/photobleaching recovery/protein mobility) ......... .... J. Schlessinger, L. S. Barak, G. G. Hammes, K. M. Yamada, I. Pastan, W. W. Webb, and E. L. Elson 2909-2913
Food, drug, and cosmetic dyes: Biological effects related to lipid solubility (molluscan neurons/toxicity/ uncouplers/anticoagulants/brain uptake) ....................................... Herbert Levitan 2914-2918
Replication of pea enation mosaic virus RNA in isolated pea nuclei (RNA polymerase/virus specificity) ... .............................................................. C. A. Powell and G. A. de Zoeten 2919-2922
Hemoglobin F synthesis in vitro: Evidence for control at the level of primitive erythroid stem cells (Hb F regulation/erythroid stem cell differentiation/erythropoietin/hemoglobinopathies) ..................
. ................................... Th. Papayannopoulou, M. Brice, and G. Stamatoyannopoulos 2923-2927 Epigenetic variation of cultured somatic cells: Evidence for gradual changes in the requirement for factors
promoting cell division (tumor progression/crown gall/cytokinin habituation) ....................... ....................................................... Frederick Meins, Jr., and Andrew Binns 2928-2932
Specific changes in the collagen phenotype of BALB 3T3 cells as a result of transformation by sarcoma viruses or a chemical carcinogen (collagen types/4-nitroquinoline 1-oxide/simian virus 40) ................. . ...... .............................................. Ryu-ichiro Hata and Beverly Peterkofsky 2933-2937
Appearance of a chromatin protein during the erythroid differentiation of Friend virus-transformed cells
(Correction) (nonhistone proteins/dimethyl sulfoxide/erythroleukemia cells/histones) ............... ................................................ .Franrce Keppel, Bernard Allet, and Harvey Eisen 3104
GENETICS Cell-to-cell stimulation of movement in nonmotile mutants of Myxococcus (intercellular communication/ swarming/gliding/development) .............................. Jonathan Hodgkin and Dale Kaiser 2938-2942
Serial transfer of a human gene to rodent cells by sequential chromosome-mediated gene transfer (X-linked genes/human gene mapping/somatic cell genetics/hypoxanthine phosphoribosyltransferase/integration)
............................. .. ..................... Raghbir S. Athwal and 0. W esley McBride 2943-2947 Detection of active heteropolymeric 3-glucuronidase in hybrids between mouse cells and human fibroblasts
with f-glucuronidase deficiency (mucopolysaccharidosis type VII/somatic cell genetics/mouse antisera against human 3-glucuronidase/electrophoresis) ..................................... C. J. Chern 2948-2952
Segregation of genetic information for a B-tropic leukemia virus with the structural locus for BALB:virus-1 (molecular hybridization/endogenous type-C RNA viruses/N- and B-tropic viruses/virus-induced leukemia) . ................ Keith C. Robbins, Cirilo D. Cabradilla, John R. Stephenson, and Stuart A. Aaronson 2953-2957
Specific action of T4 endonuclease V on damaged DNA in xeroderma pigmentosum cells in vivo (excision re- pair/incision/hemagglutinating virus of Japan/4-nitroquinoline 1 -oxide/UV irradiation) ............
. .............. ! .......... Kiyoji Tanaka, Hiroshi Hayakawa, Mutsuo Sekiguchi, and Yoshio Okada 2958-2962 Recombinant plasmid that carries part of the nitrogen fixation (nif) gene cluster of Klebsiella pneumoniae
(cloning/distamycin A/restriction enzymes/phage P1 cotransduction) .............................. . ................................... Frank C. Cannon, Gerard E. Riedel, and Frederick M. Ausubel 2963-2967
Mannosidosis: Assignment of the lysosomal a-mannosidase B gene to chromosome 19 in man (gene map- ping/cell hybrids/inherited storage disease) ....................... M. J. Champion and T. B. Shows 2968-2972
Genetic instability in Drosophila melanogaster: Putative multiple insertion mutants at the singed bristle locus (mutable genes/back mutation/spontaneous mutation) ..................................... .............................................. .M. D. Golubovsky, Yu. N. Ivanov, and M. M. Green 2973-2975
Mutants of Escherichia coli lacking in highly penicillin-sensitive D-alanine carboxypeptidase activity (Esch- erichia coli peptidoglycan/penicillin target/endopeptidase/transpeptidase) ........................ ....... ............................ Michio Matsuhashi, Yohtaroh Takagaki, Ichiro N. Maruyama, ....... Shigeo Tamaki, Yukinobu Nishimura, Hideho Suzuki, Utako Ogino, and Yukinori Hirota 2976-2979
Simultaneous deletion of D-alanine carboxypeptidase IB-C and penicillin-binding component IV in a mutant of Escherichia coli K12 (brute-force powerful muthgen selection/soluble and particulate enzymes/peni- cillin-binding protein) ............... Makoto Iwaya and Jack L. Strominger 2980-2984
.IMMUNOLO)GY Production of antibodies against influenza virus by somatic cell hybrids between mouse myeloma and primed spleen cells (cell fusion/anti-hemagglutinin antibodies/malignancy).
Suppressor cell regulation of immune response to tumors: Abrogation by adult thymectomy (regulatory T cell induction/T cell response to autochthonous murine sarcoma virus-induced sarcomas/complete Freund 's adjuvant/thymus-d erived lymphocyte).............................
(Continued on page viii)
1X
This content downloaded from 169.229.32.136 on Wed, 7 May 2014 20:13:47 PMAll use subject to JSTOR Terms and Conditions
Specific radiolabeling of a cell surface receptor for epidermal growth factor (heterobifunctional crosslinkeri photoactivable reagent/crosslinking of membrane proteins/mitogen receptor) .......... Manjusri Das, . ... ,Tokichi Miyakawa, C. Fred Fox, Rebecca M. Pruss, Aharon Aharonov, and Harvey R. Herschman 2790-2794
Isolation and identification of aliphatic short-chain acylcarnitines from beef heart: Possible role for carnitine in branched-chain amino acid metabolism (isobutyrylcarnitine/isovalerylcarnitine/propionylcarnitine/ butyrylcarnitine) ...............................L. L. Bieber and Y. R. Choi 2795-2798
Source of oxygen in the CO2 produced in the bioluminescent oxidation of firefly luciferin (luminescence/lu- ciferase/oxygen exchange/reaction mechanism) ................................................
... .Osamu Shimomura, Toshio Goto, and Frank H. Johnson 2799-2802 Molecular weight of bacteriorhodopsin solubilized in Triton X-100 (membrane proteins/sedimentation
equilibrium/purple membrane/halobacteria) ....... Jacqueline A. Reynolds and Walther Stoeckenius 2803-2804 Histones: Metabolism in simian virus 40-infected cells and incorporation into virions (DNA synthesis/histone
phosphorylation/Triton-acid-urea gels) ................................ K. B. Tan 2805-2809 Selective association of the trout-specific H6 protein with chromatin regions susceptible to DNase I and DNase
II: Possible location of HMG-T in the spacer region between core nucleosomes (nonhistone proteins/mi- crococcal nuclease/trout testis) .......... Beatriz Levy W., Norman C. W. Wong, and Gordon H. Dixon 2810-2814
DNA or RNA priming of bacteriophage G4 DNA synthesis by Escherichia coli dnaG protein (ADP/DNA binding protein/bacteriophage ST-1 DNA/DNA replication) ................................. Sue Wickner 2815-2819
Structural convergence during protein evolution (single-base substitutions/genetic code/amino acid substi- tutions/Darwinian evolution/protein secondary structure) ........... ............................
...................................... F. R. Salemme, Michael D. Miller, and Steven R. Jordan 2820-2824 Sugar uptake into brush border vesicles from normal human kidney (glucose/membranes/proximal tubule
transport) .................................. R. James Turner and M. Silverman 2825-2829 Extracellular labeling of nascent polypeptides traversing the membrane of Escherichia coli (alkaline phos-
phatase/protein synthesis/protein secretion/membrane-bound polysomes) ......................... . ....................... Walter P. Smith, Phang-C. Tai, Robert C. Thompson, and Bernard D. Davis 2830-2834
Method for obtaining a high resolution protein map starting fromn a low resolution map (protein crystallogra- phy/phase extension technique) ...................... R. C. Agarwal and N. W. Isaacs 2835-2839
Synthesis of full-length DNA copies of avian myeloblastosis virus RNA in high yields (RNA-directed DNA nucleotidyltransferase/complementary DNA/nucleic acid hybridization/methylmercury-agarose gel electrophoresis) ...................... Jeanne C. Myers, S. Spiegelman, and D. L. Kacian 2840-2843
BIOPHYSICS The living state and cancer (a 3 period/methylglyoxal as electron acceptor/doping of protein/glyoxalase and entropy/SH catalysis/oncogenic paradox) ................................ Albert Szent-Gyorgyi 2844-2847
BOTANY Thermosensitive step associated with transfer of the Ti plasmid during conjugation: Possible relation to transformation in crown gall (plant tumors/octopine) . ................. .Jacques Tempe, Annik Petit, Marcelle Holsters, Marc van Montagu, and Jeff Schell 2848-2849
CELL BIOLOGY Isolation of folded chromosomes from the yeast Saccharomyces cerevisiae (chromosome organization/su- percoiled DNA) .................................. R. Pifion and Y. Salts 2850-2854
Extensive disulfide bonding at the mammalian cell surface (LETS glycoprotein/fibroblasts/transformation/ polyacrylamide gels/intermolecular complexes) ....... I....... Richard 0. Hynes and Antonia Destree 2855-2859
Topographic separation of adenylate cyclase and hormone receptors in the plasma membrane of toad erythrocyte ghosts (membrane vesicles/l-receptor-enzyme coupling/mobile receptor hypothesis) ................ . ................................... N. Sahyoun, M. D. Hollenberg, V. Bennett, and P. Cuatrecasas 2860-2864
Effects of antitubulins on the redistribution of crosslinked receptors on the surface of fibroblasts and epithelial cells (Colcemid/microtubules/capping/lamellar cytoplasm/microtubule-destroying drug) .............
............. .................. L. V. Domnina, 0. Y. Pletyushkina, J. M. Vasiliev, and I. M. Gelfand 2865-2868 Regulation of DNA synthesis: Age-dependent cooperation among Gl cells upon fusion (cell cycle/multinucleate
cells/cell fusion/inducers of DNA synthesis) . .Potu N. Rao, Prasad S. Sunkara, and Barbara A. Wilson 2869-2873 Protease effects on specific growth properties of normal and transformed baby hamster kidney cells (anchorage
dependence/serum requirement/saturation densitytplasmin/trypsin active-site inhibitors). ................................................................ .McKay Brown and Don Kiehn 2874-2878
Glucocorticoid-stimulated accumulation of mouse mammary tumor virus RNA: Increased rate of synthesis of viral RNA (steroid receptor/molecular hybridization/hydroxylapatite chromatography) ........... .......... ......Gordon M. Ringold, Keith R. Yamamoto, J. Michael Bishop, and Harold E. Varmus ................................2879-2883
Inhibition of cytokinesis in Friend leukemia cells by membrane mobility agents (multiple nuclei/giant cells/ A2C/Flomol fluorescent probe) ................................ ....................Shlomo Lustig, Nechama S. Kosower, Dov. H. Pluznik, and Edward M. Kosower ............................. 2884-2888
Control of growth by picolinic acid: Differential response of normal and transformed cells (cell synchrony/ chelating agents/NAD+/pyrid ine d erivatives/viral transformation)................. ................. .............J. A. Fernandez-Pol, Vincent H. Bono, Jr., and George S. Johnson ........................ 2889-2893
(Continued on page ix)
This content downloaded from 169.229.32.136 on Wed, 7 May 2014 20:13:47 PMAll use subject to JSTOR Terms and Conditions
