September 2016

Frost & Sullivan

Transformational Health Helping Companies Invent Their Future in the New Healthcare Ecosystem

2

The ‘Transformational Health’ Practice

3

Thought Leadership Across Healthcare

Lifesciences

Ad

van

ced

Med

Tech

Connected

Health

Vis

ion

ary

Healt

hcare

• Personalized

Medicine

• Clinical Diagnostics

• Life Science

Research Tools

• Biotech/ Pharma

• Medical Imaging

• Patient Monitoring

• Medical Products,

Implants, & Tools

• Healthcare IT

Infrastructure

• Population Health

• Virtual Care

• Interoperability

• Future Care

Paradigms

• Business Model

Innovation

• HC Mega Trends

• Integrated Payer

Models

Frost & Sullivan’s Healthcare Practice Covers 4 Key

Research Areas In an increasingly convergent industry

landscape, no firm provides the level of

thought leadership and deep coverage

across the healthcare industry

landscape like Frost & Sullivan.

As market shifts occur due to:

• Provider Consolidation

• Site of Care Evolution

• Value Based Compensation

• Disruptive Innovative Therapeutics

• Service Centric Business Models

• Changing Influencers / Decision

Makers

How will your organization adapt to

capture new revenue streams?

4

Transformation Driven by 8 Critical Trends

Critical Trends for

Transformation

Impact

1. Digital Health

2. Health Data Science

3. Precision Medicine

4. Business Models and

Service Solutions

5. Emerging Markets: Beyond

BRIC

6. Outlooks and Future of

Industry Sectors

7. Medical Technology

Disruptors

8. From Hospital to Home

• Continuum of care

• Payer ecosystem

• Person/Patient

• Location of care (location

agnostic)

• Sickness model to wellness

• Procurement and Distribution

• Roles of different stakeholders

• Service Industry

An

aly

st

Insig

hts

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Alignment of Content / Insights to the Identified Critical Trends

Digital Health Health Data

Science

Medical Technology

Disruptors Precision

Medicine

Care Provider

Transformations

Business Model &

Service Solutions

Emerging

Markets Outlooks &

Future of Markets

Life

Sciences

Advanced

Medical

Technologies

Connected

Health

Visionary

Healthcare

Patient

Engagement

Models

NGS

Informatics

Targeted

Therapies

Chronic

disease

monitoring

Digital

Health

Strategies

for Med Tech

Companies

Telehealth

Consumer

Wearables

mHealth

Care

anywhere

models

AI enabled

decision

support

Industry

convergence

Image

processing,

Clinical

applications

Big Data,

Analytics

Person

centric care

models

Future of

healthcare

workforce

Healthcare

consumeriz

-ation

Innovating

cost of care

& access

models

Macro

predictions

& Mega

Trends

Practice Focus:

Risk Sharing

Models in

Medical

Imaging

Equipment

Deployment

Hybrid

treatment

suites,

Landscape

by Sites of

Care

Future of

Care

Provision -

Hospital

Sector

Landscape

Point of

Care

Testing

Clinical

Lab

Services

Biosimilars,

CRAMS Regen

Medicine

Companion

Diagnostics

Pop Health,

Data

manage,

analytics,

Exchange

Virtual Care

New

Device

models

Genomics

IT and data

analytics

Everything

Value-

based

Care, Risk

Sharing in

IT

Mobile and

Virtual Care

Health IT

and

Telehealth

Next

Generation

Therapies

GLOBAL

Sector

Tracker -

Innovative

Company

Clinical

applications

Big Data,

Analytics

Future of

Care

Provision in

Emerging

Markets in

APAC

China

Healthcare

Outlook

(Emerging +

Developed)

Medical

Devices

Outlook

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Frost & Sullivan Programs

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1. Visionary Healthcare

Business Model Innovation: RISK SHARING/ OUTCOMES SERVICE MODELS E-COMMERCE CONSUMER ENGAGEMENT OPEN SOURCE INNOVATION

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Disruptive Technologies: 3D/ 4D Printing Artificial Intelligence/ Analytics Nanotechnology Computing Hardware IoT

2

Site of Care Innovations: Smart Hospitals Virtualization Aging in Place Rural vs Urban Retail

3

1

Business Model

Innovations

Site of Care

Innovations

3

2

Disruptive Technologies

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2. Lifesciences

2

Invitro Diagnostics

& Research

Tools (Alternate Site

Care)

Pharmaceuticals & Biotech

Track (Targeted Therapies)

1

3 Emerging

Technologies (Disruptive Business

Models)

2

Emerging Technologies: MARKET INSIGHTS • Regenerative Medicine • Biosimilars, Generics 2.0 • CRAMS • Digital Pathology • Downstream Bioprocessing • AntiBody Drug Conjugates

3

Pharmaceuticals & Biotech MARKET LANDSCAPES & OUTLOOKS • Oncology • Diabetes/Metabolic Diseases • Neurology • Cardiovascular Diseases • Infectious Diseases Invitro Diagnostics & Research Tools MARKET ASSESSMENTS • Molecular Dx (incl. Companion Dx) • POCT • Clinical Lab Services • Next Generation Sequencing • Chromatography/Research

Antibodies

1

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3. Connected Health

3

Care Model Transformation

Technology and the Care Continuum

1

2

Healthcare Information Technology

Care Model Transformation Population Health Management Patient/Consumer Engagement Big Data Chronic Disease Management Prevention & Wellness

3

Healthcare Information Technology • Data management (cloud, content

management) • Data analytics • Data exchange • Provider and Payer applications

2

Technology and the Care Continuum: • Aging in place • Virtual Care • Telehealth and mHealth • Consumer health

1

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4. Advanced Medical Technologies

4

3 Care and Business Services

Transformations

Diagnostics and Monitoring

Technologies

1

2

High Impact Interventional &

Therapeutic Technologies

Care & Business Services Transformation: • Innovative Business Models • Managed Equipment and Risk Sharing

Partnership Models • Procurement Changes, Role of

Logistics & Supply Chain

3

High Impact Interventional & Therapeutic Technologies: • Surgical Technologies, Wound Care,

Orthopedics • Cardiac & Vascular therapies • Infection Control; Drug Delivery

2

Diagnostics & Monitoring Technologies : • Radiography, DR, Ultrasound • Interventional X-ray, Hybrid OR • CT, MRI, Nuclear Medicine • Imaging Informatics • Managed Services, Refurbished

1

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Advanced Medical Technologies

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MedTech – Product Centric Coverage

Vascular (Cardiology and

Peripheral)

Medical Devices

Surgery Infusion Therapy

Valves

AFIB Devices

Stents and grafts

Catheters and Guidewires

Rhythm Management

Devices

Surgical Drapes, Gowns & Gloves

Sharp and Safety Devices

Image Guided Surgery Devices

Pumps

Diabetes Care

Intra venous Therapy

Infection Control

Disinfection and Sterilization Equipment

Hand Disinfectants

Gels & Scrubs

Others

Urology Devices

Ophthalmic Devices

Skin Integrity

Neurosurgery

Wound Care Orthopaedics

Wound closure

Wound Debridement

Traditional and Moist Dressings

Advanced Wound

Management

Regenerative Therapy

Joint Replacement

Trauma Fixation

Braces and Supports

Spinal Surgery

Stimulation Devices

Compression Therapy

Ortho-biologics Peripheral

Devices

Enteral Nutrition

Pre-filled Syringes

Energy Based Devices

Patient Prepping

Custom Procedure Trays

P.S: The above mentioned list is not exhaustive

Disinfectants

Endoscopy – incld. ENT, GYN

Surgical Suites

Compliance Monitoring

Services Automation

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How the Advanced Medical Technologies Program Supports Business Strategy for Medical OEM’s

Business Need

New Markets Product

Development M&A, Alliances

Support Scenario Planning

Strategy Development

Implementation & Process

Core Interventional / Therapy Areas

Next Generation

Payor Trends

Customer Segments

Digital Strategies

Innovation

Surgery Cardio- Vascular Orthopaedics Wound Care

Clinical Pathways

Competing Therapies

Procurement Models User Behaviour &

Attitudes

Outcomes based Reimbursement

Sales Models, Logistics

Devices

Pharma

Diagnostics

Supported by…………

-Surgical

technologies

-Infection control

-Patient monitoring

-Orphan diseases

-Drug delivery

-Biosimilar mAbs

-Biomarkers

-Molecular

diagnostics

-Predictive testing

-Imaging dx

Therapy Convergence

New Business Models

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Alignment with Boston Scientific’s Portfolio

Orthopaedics

Joint Replacement

Trauma

Fixation

Braces & Supports

Spinal

Surgery

Endoscopy

Ortho-

biologics

*Please Note: The above mentioned list is not exhaustive

Medical Devices

Surgery

Image Guided and Navigation

Stimulator Devices

Neurosurgery Devices

Urology Devices

Pain Management

Surgical Suites

Vascular

(Cardiology and

Peripheral)

AFIB Devices

Emerging Therapies

Stents Catheters and grafts

Structural Heart

Rhythm Management Devices

Peripheral Devices

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Structure of Deliverables – Syndicated Research

Market Assessments and Outlooks (Market Engineering)

• Solutions / Sector Performance

• Forecasts, Growth Rates, Market

Share

• Penetrations Rates, Adoption

• Price Points

• Sales Channels, Distribution

• Industry / Sector Drivers, Restraints

• Customer Segments

• Competitive Landscape

• Scenario Analysis

• Future Outlook

• Strategic Recommendations

Thought Leadership Perspectives (Market Insights)

• Regional Healthcare System

Landscapes

• Competitive Profiles

• Risk Sharing Models in

Solutions Deployment

• Evolving Procurement Models and Role

of GPO

• Innovative Therapies

• Emerging / Disruptive Technologies

• Service and Solutions Models

MedTech Sector Newsflash/ Alerts (Monthly Trackers)

• Innovative Companies

• Product Launches

• Policy / Regulatory Announcements

• Partnerships, Alliances and

Acquisitions

• Innovative Solutions

• New Business Models

• New Players

• Market Drivers

• Market Metrics

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Structure of a Growth Partnership

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What We Provide as a Growth Partner Core Market Intelligence combined with Customized Content

On Stream Market Intelligence Platform

via Hundreds of Market Studies

• Market Size and Forecasts

• Pricing, Unit Shipment, Forecasts

• Competitive Landscape and Share

• Value Chain and Business Models

• Pipeline / Product Analysis

• Market Trends - Drivers & Restraints

• Emerging Geographic Markets

• Coverage of Key Industry Trends and

Assessment of Impact of Trends

• Continuous Tracking of Key Healthcare

Markets

Interactive Services

• Client Specific Deliverables: Specific

deliverables using analyst hours to deep dive on

issues of relevance to Boston Scientific

• Virtual Analyst Briefings: enabling face to face

interaction with a specialist on a particular

market or technology

• On Demand Insights: leveraging our global

team to provide regional insights for specific

markets not otherwise covered within syndicated

research

• Mega Trends: a novel platform of global

transformative forces expected to change the

future healthcare landscape and provide

opportunities for Boston Scientific’s future growth

Customization to Boston Scientific’s

Business Context

Assist Boston Scientific in evaluating the

addressable market, business planning and better

positioning of solutions to prospective customers

and / or partners

Combined with

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Access for Boston Scientific’s user/s to Frost & Sullivan’s research* within Healthcare

Growth Partnership Service Outline: 1. Market & Strategic Insights Research – Advanced Medical Technologies

3. Other Value Adding Services 2. Interactive Services 1. Market & Strategic Insights

Research

Hospital / Services Profiling -Hospital Profiling & Segmentation -Medical Device Distributor Profiling -Evolving Care Delivery Models -Healthcare Policy & Reform -Medical Devices Supply Chain Structures

Cardiovascular & Cardiac Surgery Stents Structural Heart Interventional Cardiac Products Peripheral Vascular Products Cardiac Rhythm Management Emerging Cardiovascular Interventions Electrophysiology

Emerging Markets - Innovative Therapies - Emerging Markets Regional Outlook - Emerging Markets Hospitals Outlooks - Distributors Profiles - Business Models and Service Solutions

Neurosurgery -Deep Brain Stimulator Devices - Neurosurgery Devices - Connected Hospitals -Therapeutic Beds

Minimally Invasive Surgical Devices & Orthopedics - Endoscopy - Spinal Devices - Image Guided Surgery and Navigation Devices -

Other Medical Devices

-Durable Medical Equipment & Supplies -Biosurgery - Electro medical Devices -Urology Devices -Intravenous Therapy Devices

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Monthly Industry Sector Trackers:

Growth Partnership Service Outline: 1. Market & Strategic Insights Research – Advanced Medical Technologies

3. Other Value Adding Services 2. Interactive Services 1. Market & Strategic Insights

Research

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Examples of our Interactivity and Workshops

Personalized Briefings: Hot topics often require a

broader audience to be immersed in a potential

growth opportunity. Our briefings provide

immediate solutions. Examples are:

• Emerging market briefings (choosing geography

related to area of interest)

• Briefings on current events, regulatory changes,

megatrends

• Briefings on market opportunities or growth or

changes that is within the areas we cover

• Briefings on supply chain or distribution

challenges

• Quarterly briefing to the management team on

the outlook for the next quarter across key

markets across the world

A fundamental part of our relationship philosophy is value personalization through availability and access

to our global teams, enabling the integration of market, technology and innovation within our clients.

3. Other Value Adding Services 1. Market & Strategic Insights

Research 2. Interactive Services

Growth Partnership Service Outline: 2. Interactive Services & Briefings

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3. Other Value Adding Services 1. Market & Strategic Insights

Research 2. Interactive Services

Growth Partnership Service Outline: 2. Interactive Services & Briefings

Public - Analyst Briefings:

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3. Other Value Adding Services 1. Market & Strategic Insights

Research 2. Interactive Services

Growth Partnership Service Outline: 2. Interactive Services & Briefings

Industry Sector Specific Analyst Briefings:

Virtual Analyst Briefing : example 1

Evolving Healthcare Delivery Landscape

• Scope to be coordinated with Frost & Sullivan analyst team 6

weeks prior to delivery.

• Content (20-25 slides) to be delivered 1 week prior to

presentation Boston Scientific team (via web or onsite)

• Recording and presentation slides to be provided for

dissemination to Boston Scientific team.

• Debrief one week following event to discuss follow on support.

Virtual Analyst Briefing : example 2

Supply Chain Disruptions & Transformations

• Scope to be coordinated with Frost & Sullivan analyst team 6

weeks prior to delivery.

• Content (20-25 slides) to be delivered 1 week prior to

presentation with Boston Scientific team (via web or onsite)

• Recording and presentation slides to be provided for

dissemination to Boston Scientific team.

• Debrief one week following event to discuss follow on support.

* Other topics willing to be considered and scoped with input from the Boston Scientific team.

Sample Evolving Healthcare Delivery Landscape topics to be

considered:

Impact of value based care

delivery and payment

mechanisms.

Aging in Place- New

opportunities for products &

services

Ongoing implications of PPACA

implementation and roll out

Optimizing care delivery (lean

innovations, role of analytics,

etc.)

Sample Supply Chain Disruptions & Transformation topics to be

considered:

New opportunities for services to

care delivery providers.

New opportunities for services to

medical device manufacturers.

Strategic assessment of existing

and emerging competitive threats

The analytics revolution in supply

tracking and information services.

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3. Other Value Adding Services 1. Market & Strategic Insights

Research 2. Interactive Services

Growth Partnership Service Outline: 2. Interactive Services & Briefings

Conference Coverage

• Frost & Sullivan will attend conferences to

support your team in answering your

company’s specific KIQs to remain

competitive and aware of market

opportunities

• This service includes:

o KIQ development

o Playbook/schedule creation

o Primary and secondary intelligence

gathering at the event

o Comprehensive deliverable presenting

key findings and implications

A fundamental part of our relationship philosophy is value personalization through availability and access

to our global teams, enabling the integration of market, technology and innovation within our clients.

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3. Other Value Adding Services 1. Market & Strategic Insights

Research 2. Interactive Services

Growth Partnership Service Outline: 2. Interactive Services & Briefings

Frost & Sullivan is your ideal partner for a Whitepapers / Video Whitepapers because:

• Frost & Sullivan produces more than 100 white papers per year! We have written research based whitepapers for over 50 years

Experience

• Frost & Sullivan has research credibility, brand recognition, and ability to influence with research.

Credibility and Integration

• The Frost & Sullivan name has broad recognition across vendors, around the globe, and with the end-user community.

Powerful Brand Recognition

• Frost & Sullivan has extensive experience developing and promoting white papers.

Whitepaper Best Practices

• 40 offices with 1,800 consultants/analysts; 12,500 clients per year; 80 clients in 80 countries; 3 million Web visitors

Global Footprint and Impact

• Frost & Sullivan has an extensive network of global media, webcasts, events, content distribution systems and social media.

Promotional Machine

• Broad Industry Coverage and Career Tracking

Industry Knowledge

• Multiple formats to maximize communication and influence.

Multimedia Skills

• Experience with fully integrated marketing campaigns to maximize the impact.

Integrated Marketing

Campaigns

• A style of trust and openness, and we make it fun to work together.

Collaborative Style

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1. Market & Strategic Insights

Research 2. Interactive Services 3. Other Value Adding Services

Growth Partnership Service Outline: 3. Value Adding services

In addition to the core GPS services outlined in this

proposal, as a client Boston Scientific will also

receive the following additional benefits as a

subscriber:

Free invitations

to Industry

Relevant events

Invitations to

Interactive

Analyst

Briefings

Industry

Tracker,

Newsletters and

Market Insights

Each user has a

dedicated

homepage on

www.frost.com

Dedicated

Account

Management

Team

Ability to

influence future

research topics

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Milestone Support for Boston Scientific - representative Integrating Business Planning into the Growth Partnership Unlocks Strategic Value

Boston Scientific’s Planning and Budgetary Timelines

March December September

Frost & Sullivan’s 12 Month Customized Services Platform

Access to Hundred’s of Healthcare Market Studies

Covering Infrastructure, Industry Transformation,

Cardiovascular devices , Surgery and more.

• Specific Deliverables on

Atrial Fibrillation

Devices Landscape in

Asia Pacific

• Analyst Interactions

• Syndicated Studies on a

range of Surgical

solution areas

• Analyst Briefings

• Analyst Briefings

• Growth Innovation

and Leadership

Events

• Deep dive on end user

perceptions / needs in

Asia Pacific

• Analyst Interactions

• Med Devices and

Connected Health

Events

• Best Practices

• Strategic

recommendations

for Boston Scientific

- Emerging Markets -

3 Year Horizon

• Strategic Advisory

Session – Theme TBD

• Workshop / Mega

Trends Workshop

• Learning Solution

Rollout – ‘Key Account

Management’ / ‘Selling

on Value’ Training

• Competitive Intelligence

support

June

- Sample Inclusive Proposal Elements

- Customised Consulting Elements

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Bespoke Advisory Services

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NEW MARKETS

Geographic expansion, market entry strategy

PRODUCT DEVELOPMENT

New product development and launch,

innovation management

M&A, ALLIANCES SUPPORT

Partner/target search, market and commercial

due diligence

SCENARIO PLANNING

Forecasting, business planning, business

case development

STRATEGY DEVELOPMENT

Portfolio optimisation, opportunity evaluation,

business case development, financial analysis

IMPLEMENTATION & PROCESS

OPTIMISATION

Performance and cash flow optimisation,

transformation implementation, best practices

MARKETING SUPPORT

White papers, customer engagement, brand

support, customer research

Healthcare Growth Consulting Expertise Growth Processes We Typically Address in Bespoke Engagements

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Our Focus on Customer Research Customer Research Capability to Generate inputs for Strategic and Operational Marketing Decision Making

Market

Feasibility

Market

Segmentation

Usage &

Attitudes

Brand Equity,

Image &

Positioning

Product Development Customer Satisfaction

& Value

Distribution

Channel

Testing

Value Based

Pricing

0

20

40

60

80

100

1

Price

Navigation

Phone

Portability

Digital Radio

Multi-Media

3

2

1

Maximum Reach

Pro

fit

4 5

6

Advertising / Comms

Testing

Pricing

• Strategy Development

• Optimization Elasticity

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Snapshot Global Case Studies Please refer to Appendix for Asia Pacific case studies

• Consumer Analysis of Medical Imaging and Patient Monitoring Markets in Turkey, Iran, Saudi Arabia, Poland and

Egypt . Including Usage trends, affordability challenges, needs and current gaps, increase/ decrease in diagnosis

rates, impact of macro factors on diagnosis rates, customer satisfaction rating for different competitors, company

perception and price associations and key differentiators for decision making are assessed.

• Drivers & Restraints Analysis to Forecast International Growth of Medical Imaging Segments

• Tailored market forecasts and reports for all countries and market sectors. Our highlighting of drivers and

restraints around certain evolving segments and imaging applications allowed our client to prioritize its

planning and marketing activities.

• Market Assessment of the Home Healthcare Solutions Segments in Five Emerging Countries. Frost & Sullivan

worked to identify opportunities and growth strategies to increase their market presence in each emerging country

prioritised.

• Dynamics and Opportunities for Healthcare Infrastructure Development in Africa and Eastern Europe

• Our client was able to understand the relative attractiveness and feasibility of building their capabilities in each

country while also build awareness of what their competition is developing in each area

Examples (type) of work experience Client (Examples)

• Strategic Analysis of Medical Imaging and Patient Monitoring Markets . Frost & Sullivan provide actionable

insights on the market shares of key players, their revenues (current & future), competitive factors by segments

and illustrations of key elements.

• Assessment of Clinical Systems Devices Market in Latin America. The client was provided with in-depth analyses

of their key market segments in the devices market, insights into customers' purchase processes and brand

perceptions and overview of competitors’ offerings

• Strategic Analysis of Medical Imaging and Patient Monitoring Markets in Turkey, Iran, Saudi Arabia, Poland

and Egypt. Frost & Sullivan identified all required information by client; market shares of key players, their

revenues (current & future), competitive factors by segments and illustrations of key elements

Global Healthcare Technology

Company

Global Medical Devices &

Technologies Companies

Global Healthcare Technology

Company

Fortune 500 Company - Leading

Position Within Many Medical

Device Markets

Global Medical Devices

&Technologies companies

Global Healthcare Solutions

Company

Global Healthcare Technology

Company

Global Healthcare Technology

Company

• Strategic Assessment of the C-arm Market in South Africa

• Frost & Sullivan developed a clear, country specific growth strategies both targeting specific public and private

hospital customer groups within a prescribed time period

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www.frost.com

Contact

Name : Aris Ibrahim Position : Account Manager

Phone: +60123451834

Mail: aris.ibrahim@frost.com