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Function Express: Architecture
Integrated DB
(Oracle 9i)
LocalDB (MySQL)
Chip DataGene AnnotationsAnalysis
Chip DataVirtual Experiment Data
LocalDB (MySQL)
Individual
Laboratory
Bioinformatics Core
MGA MAC
Compute Nodes
Function Express: Viewers
Clinical Data
Probeset Data
Probeset Comments Category Comments
Category History
• Are co-expressed genes co-regulated?
• What regulatory networks are operating/perturbed in your experimental paradigm?
• What pathways/processes emerge from a set of ‘interesting’ genes?– Promoter Analysis Pipeline
– Gene Network Viewer
– IPA
Function Express: What to do after analysis?
Acknowledgments
Promoter PipelineGary Stormo
On-site PersonnelLi-Wei ChangHrishikesh DeshmukhBurr FontaineCaerie HouchinsGeorge JosephSunita KoulRekha MeyerMukesh SharmaJoanne Zhao
Software Project ManagerSrikanth Adiga
Off-shore PersonnelAnuj TiwariJaydeep ChovatiaRahul JainMadhumita ShrikandeMadhurima BhattacharjeeAshwini Patil