FUNDAMENTALOPERATIONS

FORDISPENSING

Dr. Dhaivat C. ParikhInstitute of Pharmacy, Nirma University

Dr. Dhaivat Parikh

DISCLAIMER This Presentation is Only for Internal Use.

This Presentation is meant only for giving an overview of Subject concerned to BPharm Students of Institute of Pharmacy, Nirma University.

Unauthorized Sharing, Viewing or Use of Presentation (in Full or in parts) for any other purpose is Not Allowed.

Acknowledgments to all Various Internet Source from which various Images obtained through Search Engines (like Google), which are used in Presentation –Only for Easy Explanation purpose.

Presentation Does Not have any Commercial Value.

Dr. Dhaivat Parikh

Fundamental Operations

Weighing Solids

Measuring Volume for Liquid

Solution / Dissolution

Filtration

Mixing

Size Reduction

Size Separation

Miscellaneous – Microbial Control

Dr. Dhaivat Parikh

Weighing Solids

Dr. Dhaivat Parikh

Sensitivity & Capacity

Standard Operating Procedure

Reducing Error in Weighing

Handling Corrosive Liquid

Handling Sticky Powder

Weighing Solids

Dr. Dhaivat Parikh

Measuring Volume - Liquid

Dr. Dhaivat Parikh

Error in Reading Meniscus

Handling Viscous Liquids

Handling Dark Liquid

Measuring Volume - Liquid

Dr. Dhaivat Parikh

Solution / Dissolution

Size Reduction, Mixing, Heating Check Solubility

First Dissolve in Suitable Solvent

Use Conical Flask for Mixing

Add Volatile ingredient at Last (After Heating)

Wash Powder Traces with Bulk Liquid

Volume Adjustment at Last

Viscous Liquid – Fill directly in Bottle

Dr. Dhaivat Parikh

Filtration

Dr. Dhaivat Parikh

Filtration

Tips for increasing Rate of Filtration Increase Pressure Difference Reduce Viscosity Increase Surface Area Use Filter Media of Higher PorosityCourse Filtration External Preparation – Remove Large Particles Emulsion / Suspension / Viscous Preparation Fine Filtration Filter Paper / Sintered Glass / Membrane Filter Oral Preparation

Dr. Dhaivat Parikh

Mixing

Liquid + Liquid Solution

Emulsion

Solid + Liquid Solution

Suspension

Solid + Solid

Semi Solid

Dr. Dhaivat Parikh

Size Reduction

Dry Grinding

Wet Grinding - Levigation

Dr. Dhaivat Parikh

Size Separation

Shifting

Ideally, First STEP for Using Any Solid Powder

Dr. Dhaivat Parikh

Microbial Control

Careful in Selection of Raw Material

Water Purity

Maintain Hygiene

Add Anti-bacterial, Preservative, Double-strength Chloroform Water

THANKSDr. Dhaivat C. Parikh

Institute of Pharmacy, Nirma University