7/27/2019 Fungus and Parasite

1/54

Fungus and ParasitesWhy me?

7/27/2019 Fungus and Parasite

2/54

Systemic Fungi

Dimorphic

Mold in soil, yeast in tissue

Cold=mold; Heat=yeast

Histoplasmosis Bird or Bat droppings

Mississippi and Ohio River

Blastomycosis Mississippi River

Big, Broad-Based Budding

7/27/2019 Fungus and Parasite

3/54

HIsToplasmosis & BLASTomycosis

7/27/2019 Fungus and Parasite

4/54

Coccidiomycosis

Southwest US

San Joaquin valley fever

7/27/2019 Fungus and Parasite

5/54

Skin Fungus

Tinea all skin fungi

Tinea versicolor

Odd Color Caused by Malassezia furfur

7/27/2019 Fungus and Parasite

6/54

Skin fungus

Tinea nigra

Brown/black

Cladosporium werneckii

7/27/2019 Fungus and Parasite

7/54

Skin fungus

Others are by location:

Tinea pedisAthletes foot

Tinea cruris Jock itch

Tinea corporis Body (ringworm)

Tinea capitis - Head

7/27/2019 Fungus and Parasite

8/54

Opportunistic fungi

Candida

Normal

Thrush

Vaginitisyeast infection

Diaper rash or under breasts

Immunocompromised

Esophagitis Disseminated infection

7/27/2019 Fungus and Parasite

9/54

Opportunistic fungi

AspergillusAspirateAsthma(?)

A forAcuteAngle branching

7/27/2019 Fungus and Parasite

10/54

Opportunistic Fungi

Cryptococcus Neoformans

7/27/2019 Fungus and Parasite

11/54

Opportunistic Fungi

Mucor and Rhizopus

>90 branching mold

Ketoacidosis and leukemia

Pneumocystis carinii

Pneumonia

Cyst circle yeast (not mold)

7/27/2019 Fungus and Parasite

12/54

Opportunistic Fungi

Sporothrix schenckii

Dimorphic fungus

Rose gardeners disease

7/27/2019 Fungus and Parasite

13/54

ProtozoaHaving fun yet?

7/27/2019 Fungus and Parasite

14/54

Entamoeba Histolytica

Things to remember:

Inflammatory Diarrhea

Liveranchovy paste

Flask-shaped ulcer

Cysts

Tx with Metronidazole

7/27/2019 Fungus and Parasite

15/54

7/27/2019 Fungus and Parasite

16/54

7/27/2019 Fungus and Parasite

17/54

Anchovy Paste

7/27/2019 Fungus and Parasite

18/54

Giardia lamblia

From drinking untreated water (cysts)

Flatulence, foul-smelling diarrhea

7/27/2019 Fungus and Parasite

19/54

Cryptosporidium

Starts w/ Crypto, so think AIDS

Spore, so think cysts

Causes diarrhea (surprise) The 1994 Milwaukee outbreak from water

treatment problem

7/27/2019 Fungus and Parasite

20/54

Toxoplasma

Cat feces to pregnant moms

Hydrocephalus / birth defects

7/27/2019 Fungus and Parasite

21/54

Plasmodium

Malaria

Diagnosed w/ blood smear

Tx w/ mosquito (female)

7/27/2019 Fungus and Parasite

22/54

Plasmodium

7/27/2019 Fungus and Parasite

23/54

Plasmodium

7/27/2019 Fungus and Parasite

24/54

Plasmodium

7/27/2019 Fungus and Parasite

25/54

Trichimonas vaginalis

STD

7/27/2019 Fungus and Parasite

26/54

Trichimonas vaginalis

7/27/2019 Fungus and Parasite

27/54

Trypanosoma cruzi

American

Things to remember:

Chagas (heart) disease

Reduviid bug

7/27/2019 Fungus and Parasite

28/54

Trypanosoma cruzi

Chagas problems of the heart

7/27/2019 Fungus and Parasite

29/54

Reduviid - The Kissing Bug

Dont let the

kissing bug

poop on you!

7/27/2019 Fungus and Parasite

30/54

Trypanosoma gambiense

Trypanosoma rhodesiense

African (Gambia, Rhodesia)

Things to remember

Africansleeping sickness

Tsetse fly

Tutsis are inAfrica

(Rwanda)

7/27/2019 Fungus and Parasite

31/54

Leishmania

Things to remember:

Cutaneous

Visceral (kala-azar)

Sandfly

7/27/2019 Fungus and Parasite

32/54

Leishmania

7/27/2019 Fungus and Parasite

33/54

Babesia microti

Ixodes tick

Maltese cross on blood smear

7/27/2019 Fungus and Parasite

34/54

Naegleria Fowleri

Things to remember

Fowl play 95% die in a week

Meningitis

Swimming

7/27/2019 Fungus and Parasite

35/54

Naegleria Fowleri

7/27/2019 Fungus and Parasite

36/54

Metronidazole

7/27/2019 Fungus and Parasite

37/54

WormsItll be over soon

7/27/2019 Fungus and Parasite

38/54

Tapeworms

Treat tapeworms with

niclosamide

7/27/2019 Fungus and Parasite

39/54

Taenium solium

Pork tapeworm

Causes mass lesions in the brain

7/27/2019 Fungus and Parasite

40/54

Echinococcus granulosus

Hydatid tapeworms

Granulosus think of these big cysts

mostly liver and lung

7/27/2019 Fungus and Parasite

41/54

Schistosoma

Snails, Swimmers itch, Skin, Spleen

7/27/2019 Fungus and Parasite

42/54

Clonorchis sinensis

Undercooked fish

Inflamed biliary tract

7/27/2019 Fungus and Parasite

43/54

Paragonimus westermani

Lung fluke

Western man Marlboro man lung

problems

7/27/2019 Fungus and Parasite

44/54

Ancyclostoma duodenale

Hookworm

Can penetrate feet

Can cause anemiaRemember

An=not

cyclo=round Stoma=mouth

7/27/2019 Fungus and Parasite

45/54

Ascaris lumbricoides

Scariest intestinal worm

Wandering behavior

7/27/2019 Fungus and Parasite

46/54

Enterobius vermicularis

Pinworm (vermin)

Most common parasite in US

Scotch tape test

7/27/2019 Fungus and Parasite

47/54

Strongyloides stercoralis

Threadworm

Tx with Ivermectin

7/27/2019 Fungus and Parasite

48/54

Trichinella spiralis

Worm in undercooked prok

Causes muscle inflammation & periorbital

edema

7/27/2019 Fungus and Parasite

49/54

Dracunculus medinensis

In untreated water

7/27/2019 Fungus and Parasite

50/54

Loa Loa

Transmitted by deer fly

See worm crawling on conjunctiva

7/27/2019 Fungus and Parasite

51/54

Onchocerca volvulus

From blackflies

River blindness

Onco-tumor

Cerca-circle (eye)?

7/27/2019 Fungus and Parasite

52/54

Toxocara canis

From dogs

-cara rhymes with sclera

7/27/2019 Fungus and Parasite

53/54

Wuchereria bancrofti

Elephantiasis lymph blockage

7/27/2019 Fungus and Parasite

54/54

Thank you!