13th Annual Meeting of theItalian Melanoma Intergroup

Padova, 29 - 31 October 2007

Holiday Inn - Padova Ovest

Melanoma Present and Future

Programme

Monday, 29 October 2007Aula Magna Palazzo del Bò

Opening CeremonyPresidents: P. A. Ascierto (Naples), V. Chiarion Sileni (Padova), C. R. Rossi (Padova)

9.00 Opening Addresses

9.45 MelAnOMA And MOdels Of preventiOn Chairs: C. Catricalà (Rome), M. Cristofolini (Trento) Epidemiology: classes of age for priority intervention G. L. De Salvo (Padova) The role of photoprotection A. Peserico (Padova) Organizational Models: Veneto - G. Bonavina (Padova) Toscana - L. Fioretto (Florence)

10.45 MelAnOMA And sOciety Chairs: M. Lise (Padova) andScientificDirectorofIOV(Padova) Updates in research P. Zanovello (Padova) Melanoma and the web: the Melanoma Molecular Map Project S. Mocellin (Padova) The role of Associations: P. Castorina (Piccoli Punti), A. Marchet (Lega Tumori), A. Romanini (Associazione Contro il Melanoma)

11.45 rOund tAble ethics And tOOls Of infOrMAtiOn in therApeutic chOices Chairs: R. Pegoraro (Padova), D. Boresi (Padova) Clinical Researcher, P. A. Ascierto (Naples) Patient, M. Miotti (Padova) Bioethicist, G. Marsico (Padova) Chairman of the Ordine dei Medici di Padova, M. Benato Legal medicine doctor, P. Benciolini (Padova)

Discussion

Conclusions by on. I. Marino - President of the Health Committee of the Italian Senate

13.15 WelcOMe receptiOn Caffè Pedrocchi - Via VIII Febbraio 15, Padova

Steering Committee IMI (Italian Melanoma Intergroup)Paolo A. Ascierto Oncologia Medica, Istituto Nazionale Tumori - NapoliGiovanna Bianchi Scarrà Dip. Oncologia, Biologia e Genetica - GenovaVanna Chiarion Sileni Oncologia Medica, Istituto Oncologico Veneto - PadovaFranco Di Filippo Chirurgia, Istituto Regina Elena - RomaMichele Guida Oncologia Medica, Istituto Nazionale Tumori - BariGiuseppe Palmieri Genetica Tumori, Istituto Chimica Biomolecolare, CNR - Alghero RuggeroRidolfi OncologiaMedica, Ospedale Pierantoni - ForlìAntonella Romanini Oncologia Medica, Ospedale S. Chiara - PisaCarlo Riccardo Rossi Clinica Chirurgica II, Azienda Ospedaliera- Università - Padova Ignazio Stanganelli Ist. Oncologico Romagnolo - RavennaAlessandro Testori Chirurgia, Istituto Europeo di Oncologia - Milano

Local Scientific CommitteeMauro Alaibac Clinica Dermatologica, Azienda Ospedaliera - Università di Padova Franco Bassetto Chirurgia Plastica, Azienda Ospedaliera - Università di PadovaAngelo Chiarelli Chirurgia Plastica Pediatrica, Azienda Ospedaliera-Università di PadovaGianLucaDeSalvo UfficioEpidemiologiaClinica, Istituto Oncologico Veneto, Padova Edoardo Midena Clinica Oculistica, Azienda Ospedaliera -Università di PadovaMaria Cristina Montesco Anatomia Patologica, Azienda Ospedaliera -Università di PadovaDonato Nitti Clinica Chirurgica II, Azienda Ospedaliera -Università di PadovaAdriano Paccagnella Oncologia Medica, Ospedale di Venezia - Mestre Leopoldo Rubaltelli Radiologia, Azienda Ospedaliera - Università di Padova Paola Zanovello Oncologia Sperimentale, Istituto Oncologico Veneto - Padova

SecretariatClinica Chirurgica II, Università di PadovaFederica Dottovia Giustiniani, 2 - 35128 Padovaph. 049 821 2137 - fax 049 821 8349

IMI SecretariatIlenia Visconti, Stefano Leonardivia M. Semmola - 80131 Naplesph. and fax 081 5903841

Organizing Secretariat via San Nicolò 14 - 34121 Trieste ph. 040 368343 + 1 + 15 fax 040 368808 e-mail:melanoma@theoffice.it www.theoffice.it/melanoma07

GENERAL INFORMATIONConference venueHotel Holiday Inn - Padova OvestVia Po, 19735135 Padova

LanguagesThe working languages will be Italian and English. No simultaneous translation is provided.

The present programme is subject to possible changes.More detailed information is available at the following address: www.theoffice.it/melanoma07

SCIENTIFIC INFORMATIONScientific contributions (either oral communications or posters)may be submitted and sent to the Organizing Secretariat the office (melanoma@theoffice.it). Please follow instructions and download the template from: www.theoffice.it/melanoma07The abstracts must be written in Italian.Selected topics:Dermatology, Surgery and Pathology, Medical Oncology, Basic Research.

The deadline for sending oral communicationsand/orpostersis 15 July 2007.TheOrganizingSecretariatwillconfirmreceiptofabstracts.TheScientificCommitteewill examine the oral communications/postersreceived and inform authors of the outcome by 31 July 2007.

REGISTRATION AND HOTEL BOOKINGThe Registration and Hotel Booking Form can be downloaded from www.theoffice.it/melanoma07 and sent (by fax or surface mail) to the Orga-nizingSecretariattheofficetogetherwithpaymentoftheregistrationfee.

Registration fees (inclusive of VAT)Before 31/07/2007 After 31/07/2007

IMI Member* 180,00 euro 240,00 euroNon IMI Member 240,00 euro 300,00 euroStudent/Researcher Free Free

*Provided the 2007 membership fee is paid.

The registration feeincludesparticipationinthescientificsessions,theConferencekit,thecertificateofattendance,andtheabstractsvolume.

CME CreditsThe Italian Ministry of Health will be requested to grant credits for the fol-lowingfields:oncology, dermatology and venereology, surgery.To obtaincreditsparticipantsmustattend thewholeeventandfill in theCME questionnaire and the evaluation form.TheCMEcertificatewillbesenttothehomeaddressindicatedontheregi-stration form only to those participants who have successfully metthe training target.

Monday, 29 October 2007Conference Centre Hotel Holiday Inn

14.00 registrAtiOn Of pArticipAnts

15.00 Opening

15.15 preventiOn And genetics Chairs: P.A. Ascierto (Naples), E. D’Andrea (Padova) Plenarylecture Primary and secondary prevention R. Mac Kie (Glasgow, U.K.) The dysplastic naevus syndrome M. Pizzichetta (Aviano) HereditaryMelanoma:newfindings P. Grammatico (Rome) Genetic Polymorphisms and melanoma M. Alaibac (Padova)

Discussion

Selected paper

16.30 clinicAl diAgnOsis Chairs: R. Bono (Rome), G. Girolomoni (Verona) Self-diagnosis and conventional diagnosis G. Trevisan (Trieste) New non-invasive techniques for the diagnosis of melanoma I. Stanganelli (Ravenna) How to approach naevus in paediatric age The dermatological approach - A. Belloni Fortina (Padova) The surgical approach - T. Iacopetti (Padova)

Discussion

Selected paper

17.45 pAthOlOgicAl And MOleculAr diAgnOsis Chairs: V. Ninfo (Padova), T. Faraggiana (Rome) Histo-prognostic factors: minimum guidelines for the whole national territory M.C. Montesco (Padova) A second opinion: when is it necessary? C. Clemente (Milan) Molecularclassificationofmelanoma for new therapeutic strategies G. Palmieri (Alghero)

Discussion

Selected paper

19.00 iMi generAl AsseMbly

Tuesday, 30 October 2007Conference Centre Hotel Holiday Inn

8.30 surgicAl treAtMent Of the priMitive tuMOur And Of the lyMph nOdes Chairs: D. Nitti (Padova), F. Mazzoleni (Padova) Plenarylecture Themarginsofexeresis:iseverythingdefined? N. Cascinelli (Milan) Criteria and techniques for reconstruction F. Bassetto (Padova) Can the sentinel lymph node be considered as a standard? The opinion of the surgeon - N. Mozzillo (Naples) The opinion of the nuclear medicine doctor - D. Casara (Padova) What to do when the sentinel lymph node is found in unusual sites G. Giudice (Bari) Treatment of lymph node metastasis A. Testori (Milan)

Discussion

Selected paper

10.20 fOllOW-up And distAnt MetAstAses Chairs: G. M. Verdecchia (Forlì), M. Schiavon (Udine)

Plenarylecture Evidence based follow-up C. Garbe (Tuebingen, Germany)

The role of ultrasound scanning in the diagnosis of lymph node metastases A. Tregnaghi (Padova)

A proposal by the IMI: Guidelines for Staging and Follow-up M. Guida (Bari), A. Testori (Milan)

Discussion

Selected paper

Plenarylecture Distant Metastases: what are the limits of exeresis? J. Thompson (Sydney, Australia)

12.00 lOcOregiOnAl treAtMent Chairs: G. Sotti (Padova), A. Chiarelli (Padova) Hyperthermic-antiblastic perfusion F. Di Filippo (Rome) Hypoxic antiblastic perfusion P. Pilati (Padova) Radio-hyperthermia L. Corti (Padova)

Plenarylecture Electro-chemotherapy: a new therapeutic opportunity C. R. Rossi (Padova)

Discussion

14.30 iMi scientific cOMMittee

Introduction (C. R. Rossi - Padova)

14.45 pArAllel sessiOns

Dermatology Surgery and Pathology Medical Oncology Basic Research

14.45 presentAtiOn Of the selected pOsters Chairs: M. Foletto (Padova), W. Pagani (Rovigo)

16.15 rOund tAble uveAl MelAnOMA: priMAry And MetAstAses Chairs: E. Midena (Padova), G. Cartei (Padova)

Diagnosis and treatment of the primary E. Midena (Padova) Risk factors and metastasis E. Kilic (Rotterdam, The Netherlands) The treatment of stage IV patients V. Ferraresi (Rome)

Discussion

17.15 repOrts frOM the pArAllel sessiOns And prOpOsAls fOr neW reseArch tOpics

Dermatology R. Bono (Rome) Surgery and Pathology C. R. Rossi (Padova) Medical Oncology V. Chiarion Sileni (Padova) Basic Research G. Palmieri (Alghero)

18.30 clOsing Of the pOlls

20.30 sOciAl dinner

Wednesday, 31 October 2007Conference Centre Hotel Holiday Inn

9.00 systeMic treAtMent Chairs: E. Bajetta (Milan), A. Paccagnella (Venice)

Plenarylecture Adjuvant Therapy: evidence and future prospects J. Kirkwood (Pittsburgh, USA) Adjuvant Therapy: the European experience A. Romanini (Pisa) Plenarylecture Is there a therapeutic standard for metastatic illness? A. Hauschild (Kiel, Germany) Planning of clinical trials O. Nanni (Forlì) Cerebral Metastases: a predictable event? Results of the TRECEM study V. Chiarion Sileni (Padova) Cerebral Metastases: a study proposal M. Guida (Bari)

Discussion

Selected paper

11.00 prOspects fOr treAtMent Chairs: S. Monfardini (Padova), A.Veronesi (Aviano) Immunotherapy: future or reality? Biological aspects - G. Parmiani (Milan) Clinicalaspects-R.Ridolfi(Forlì) Immuno-suppression and anti-tumoral reaction S. Mandruzzato (Padova) New drugs M. Maio (Siena) New end-points P. Queirolo (Genoa)

12.00 pOsters AWArd cereMOny

12.20 AnnOunceMent Of the vOte results

12.40 fAreWell speech by the OutgOing chAirMAn Opening Address by the chAirMAn elected