General Intensive Care
Current Awareness Newsletter
April 2015
Outreach Your Outreach Librarian can help facilitate evidence-based
practise for all ICU members of staff, as well as assisting with academic study and research. We can help with literature searching, obtaining journal articles and books, and
setting up individual current awareness alerts.
Literature Searching We provide a literature searching service for any library member. For those embarking on their own research it is advisable to book some time with one of the librarians for a 1 to 1 session where we
can guide you through the process of creating a well-focused literature research and introduce you to the health databases
access via NHS Evidence.
Critical Appraisal Training We also offer one-to-one or small group training in
literature searching, accessing electronic journals, and critical appraisal/Statistics. These are essential courses that teach how to
interpret clinical papers.
Books Books can be searched for using SWIMS our online catalogue at
www.swims.nhs.uk. Books and journals that are not available on site or electronically may be requested from other locations. Please email requests to: [email protected]
Contents
1: Tables of Contents from March’s
Intensive Care journals
2: New NICE Guidance
3: NHS Behind the Headlines
4: Quick Exercise
Tables of Contents from Paediatric & Critical Care journals
If you require full articles please email me @ [email protected]
Critical Care Medicine - April Vol 43 Issue 4
Hospital-Based Acute Care Use in Survivors of Septic Shock*
Frequency, Cost, and Risk Factors of Readmissions Among Severe Sepsis Survivors*
Tissue Oxygen Saturation and Finger Perfusion Index in Central Hypovolemia: Influence of Pain*
Characteristics and Outcomes of Patients Admitted to ICU Following Activation of the Medical Emergency
Team: Impact of Introducing a Two-Tier Response System
The Role of Systemic Antibiotics in Acquiring Respiratory Tract Colonization With Gram-Negative Bacteria in
Intensive Care Patients: A Nested Cohort Study*
Lung Recruitability Is Better Estimated According to the Berlin Definition of Acute Respiratory Distress
Syndrome at Standard 5 cm H2O Rather Than Higher Positive End-Expiratory...
Dynamic Pituitary-Adrenal Interactions in Response to Cardiac Surgery*
Prehospital Aspirin Use Is Associated With Reduced Risk of Acute Respiratory Distress Syndrome in Critically
Ill Patients: A Propensity-Adjusted Analysis*
Morbidity and Survival Probability in Burn Patients in Modern Burn Care*
Differences in Vital Signs Between Elderly and Nonelderly Patients Prior to Ward Cardiac Arrest
A Qualitative Study Exploring Moral Distress in the ICU Team: The Importance of Unit Functionality and
Intrateam Dynamics*
Is Long-Axis View Superior to Short-Axis View in Ultrasound-Guided Central Venous Catheterization?*
Chest Compression Rates and Survival Following Out-of-Hospital Cardiac Arrest*
Sodium Nitroprusside–Enhanced Cardiopulmonary Resuscitation Facilitates Intra-Arrest Therapeutic
Hypothermia in a Porcine Model of Prolonged Ventricular Fibrillation*
Derivation and Validation of the Acute Organ Failure Score to Predict Outcome in Critically Ill Patients: A
Cohort Study
Clinical and Psychological Effects of Early Mobilization in Patients Treated in a Neurologic ICU: A Comparative Study*
The Formation, Elements of Success, and Challenges in Managing a Critical Care Program: Part I
Current Opinion in Critical Care - April -Vol 21 Issue 2
Recommendations for management of large hemispheric infarction
Blood pressure management in acute intracerebral hemorrhage: current evidence and ongoing controversies
Recommendations for the use of multimodal monitoring in the neurointensive care unit
Rationale for lumbar drains in aneurysmal subarachnoid hemorrhage
Reversal of the novel oral anticoagulants dabigatran, rivoraxaban, and apixaban
Diarrhoea in the critically ill
Acute, nonvariceal upper gastrointestinal bleeding
Liver transplantation in the context of organ shortage: toward extension and restriction of indications
considering recent clinical data and ethical framework
Critical Care – March 2015
Intertwining extracorporeal membrane oxygenation and continuous renal replacement therapy: sense or
nonsense?
Applicability of pulse pressure variation: how many shades of grey?
Colistin and tobramycin resistance during long- term use of selective decontamination strategies in the
intensive care unit: a post hoc analysis
Increase in cerebral oxygenation during advanced life support in out-of-hospital patients is associated
with return of spontaneous circulation
Gastro-oesophageal reflux disease increases the risk of intensive care unit admittance and mechanical
ventilation use among patients with chronic obstructive pulmonary disease: a nationwide population-
based cohort study
Timing for deep vein thrombosis chemoprophylaxis in traumatic brain injury: an evidence-based
review
Aspirin therapy in patients with acute respiratory distress syndrome (ARDS) is associated with reduced
intensive care unit mortality: a prospective analysis
Detection of acute traumatic coagulopathy and massive transfusion requirements by means of
rotational thromboelastometry: an international prospective validation study
Continuous renal replacement therapy in critically ill patients does not affect urinary neutrophil
gelatinase-associated lipocalin levels
Mechanical ventilation modes for respiratory distress syndrome in infants: a systematic review and
network meta-analysis
Identification of haplotype tag SNPs within the nuclear factor-κB family genes and their clinical
relevance in patients with major trauma
Effect of oral melatonin and wearing earplugs and eye masks on nocturnal sleep in healthy subjects in a
simulated intensive care unit environment: which might be a more promising strategy for ICU sleep
deprivation?
Closed-loop assisted versus manual goal-directed fluid therapy during high-risk abdominal surgery: a
case–control study with propensity matching
6% Hydroxyethyl starch versus other fluids for non-septic patients in the intensive care unit: a meta-
analysis of randomized controlled trials
A regional trauma system to optimize the pre-hospital triage of trauma patients
Efficacy and safety of citrate-based anticoagulation compared to heparin in patients with acute kidney
injury requiring continuous renal replacement therapy: a randomized controlled trial
Serum levels of apolipoprotein A-I and high-density lipoprotein can predict organ failure in acute
pancreatitis
Efficacy and safety of 6% hydroxyethyl starches 130/0.4 (Voluven®) for perioperative volume
replacement in children undergoing cardiac surgery: a propensity-matched analysis
Prehospital endotracheal intubation: elemental or detrimental?
β-blockers in critically ill patients: from physiology to clinical evidence
State of the art review: the data revolution in critical care
Update on the role of extracorporeal CO2 removal as an adjunct to mechanical ventilation in ARDS
Rapid response systems: are they really effective?
Cooling techniques for targeted temperature management post-cardiac arrest
Long-term sequelae from acute kidney injury: potential mechanisms for the observed poor renal
outcomes
Extracorporeal gas exchange for acute respiratory failure in adult patients: a systematic review
Angiotensin II in septic shock
A simple prognostic index based on admission vital signs data among patients with sepsis in a
resource-limited setting
An observational study of surface versus endovascular cooling techniques in cardiac arrest patients: a
propensity-matched analysis
Effects of terlipressin as early treatment for protection of brain in a model of haemorrhagic shock
A multicenter study on the effect of continuous hemodiafiltration intensity on antibiotic
pharmacokinetics
Short term amino ac id infusion improves protein balance in critically ill patients
Trauma induced coagulopathy: impact of the early coagulation support protocol on blood product consumption, mortality and costs
Postoperative pneumonia following cardiac surgery in non-ventilated patients versus mechanically
entilated patients: is there any difference?
The ratio of Th17/Treg cells as a risk indicator in early acute respiratory distress syndrome
Exposure to high concentrations of inspired oxygen does not worsen lung injury after cardiac arrest
Optimizing mean arterial pressure in septic shock: a critical reappraisal of the literature
Cathelicidin antimicrobial protein, vitamin D, and risk of death in critically ill patients
Safety evaluation on low-molecular-weight hydroxyethyl starch for volume expansion therapy in
pediatric patients: a meta-analysis of randomized controlled trials
β1-adrenoceptor stimulation promotes LPS-induced cardiomyocyte apoptosis through activating PKA
and enhancing CaMKII and IκBα phosphorylation
Early brain injury after aneurysmal subarachnoid hemorrhage a multimodal neuromonitoring study
Prognostic value of procalcitonin in respiratory tract infections across clinical settings
An ADAM10 promoter polymorphism is a functional variant in severe sepsis patients and confers
susceptibility to the development of sepsis
Advanced age is associated with worsened outcomes and a unique genomic response in severely
injured patients with hemorrhagic shock
Benefit profile of recombinant human soluble thrombomodulin in sepsis-induced disseminated
intravascular coagulation: a multicenter propensity score analysis
Human metabolic response to systemic inflammation: assessment of the concordance between
experimental endotoxemia and clinical cases of sepsis/SIRS
Does intermediate care improve patient outcomes or reduce costs?
Dynamic changes of microbial flora and therapeutic consequences in persistent peritonitis
Levosimendan affects oxidative and inflammatory pathways in the diaphragm of ventilated
endotoxemic mice
The diagnostic and prognostic significance of monitoring blood levels of immature neutrophils in
patients with systemic inflammation
Neurally adjusted ventilatory assist and proportional assist ventilation both improve patient-ventilator
interaction
Perceptions of the appropriateness of care in California adult intensive care units
Automated versus non-automated weaning for reducing the duration of mechanical ventilation for critically
ill adults and children: a cochrane systematic review and meta-analysis
Local hemostasis, immunothrombosis, and systemic disseminated intravascular coagulation in trauma and
traumatic shock
Prospective validation of pediatric disease severity scores to predict mortality in Ugandan children
presenting with malaria and non-malaria febrile illness
Superior vena cava drainage improves upper body oxygenation during veno-arterial extracorporeal
membrane oxygenation in sheep
Transferring the critically ill patient: are we there yet?
Do corticosteroids reduce the mortality of influenza A (H1N1) infection? a meta-analysis
Dexmedetomidine versus standard care sedation with propofol or midazolam in intensive care – an
economic evaluation
Propofol increases morbidity and mortality in a rat model of sepsis
Assessment of patient-ventilator breath contribution during neurally adjusted ventilatory assist in patients
with acute respiratory failure
Neurally adjusted ventilatory assist (NAVA) allows patient-ventilator synchrony during pediatric
noninvasive ventilation: a crossover physiological study
Incidence and outcome of inappropriate in-hospital empiric antibiotics for severe infection: a systematic
review and meta-analysis
Intensive and Critical Care Nursing
Monitoring and optimising outcomes of survivors of critical illness
Psychoeducational support to post cardiac surgery heart failure patients and their partners—A randomised pilot study
Evaluation of postgraduate critical care nursing students’ attitudes to, and engagement with, Team-Based
Learning: A descriptive study
Parents’ experiences of family functioning, health and social support provided by nurses – A pilot study in
paediatric intensive care
Administration of enteral nutrition to adult patients in the prone position
Simulation-based paediatric intensive care unit central venous line maintenance bundle training
Families’ experiences of their interactions with staff in an Australian intensive care unit (ICU): A qualitative
study
Chest X-ray quiz
New NICE Guidance
Medicines optimisation: the safe and effective use of medicines to
enable the best possible outcomes(NG5)
...another, to support high‐quality care. This includes transfers within...example,
when a person moves from intensivecare to a hospital ward – or from one... Stephen
Dean Consultant in Intensive Care and Anaesthesia, Leeds Teaching...
The Sherlock 3CG Tip Confirmation System for placement of
peripherally inserted central catheters(MTG24)
...central catheter in a non‐intensive care setting. When the Sherlock 3CG...analysis
based on the results for intensivecare patients presented in the studies by
Johnston...Assessment Centre considered that intensive care patients may be a
subgroup for...
Axitinib for treating advanced renal cell carcinoma after failure of
prior systemic treatment (TA333)
...because it had no best supportive care comparator as defined in the scope...of
axitinib with best supportive care. 3.2 Patients were eligible to enter...Dr Daniele
Bryden Consultant in Intensive Care Medicine and Anaesthesia, Sheffield..
Insertion of a balloon device to disimpact an engaged fetal head
before an emergency caesarean section(IPG515)
...group (p=0.55). 4.9 Admission to an intensive care unit for more than 24 hours was
needed for 6...extension of the uterine incision, reducing intensive care unit or
neonatal intensive care unit admission and reducing postoperative..
NHS Behind the Headlines
Study finds link between air pollution and stroke risk
Wednesday Mar 25 2015
"Air pollution is linked to an increased risk of stroke," BBC News reports, prompted by a
large global study in The BMJ. Researchers found an association even with brief upsurges in
air pollution levels…
Following UK dietary advice may cut heart disease risk
Thursday Mar 19 2015
"Sensible diet cuts heart attack risk in months," The Times reports after a randomised
controlled trial found evidence that following current UK diet guidelines can reduce
cardiovascular disease risk factors…
Damage to 'heart health' may start in childhood
Wednesday Mar 18 2015
"Children are suffering damage to their hearts as early as 12 due to poor diets, a study has
warned," the Mail Online reports. A US study suggests that an unhealthy diet in childhood
can quickly lead to a deterioration in "heart health"…
All teens should be vaccinated against rare strain of meningitis
Monday Mar 16 2015
"A vaccination for meningitis is to be offered to all 14-18 year-olds in England and Wales,
after a spike in a rare strain of the disease," The Guardian reports. The strain – meningitis W
(MenW) – is described as rare, but life-threatening…
UK Ebola case confirmed but risk remains low
Thursday Mar 12 2015
The Scottish nurse found to have Ebola after arriving in Glasgow from Sierra Leone has
recovered after specialist care at the Royal Free Hospital in London ...
HRT review finds increased risk of blood clots and stroke
Tuesday Mar 10 2015
'Women on HRT pills should be aware that there is a small chance of an increased risk of
blood clots and possibly stroke' BBC News report. A major review, involving over 40,000
patient records, found an increase in risk of clotting….
Quick Exercise
Have a play with Uptodate. Log in via Athens (if you don’t have an Athens
account register using your UHBristol email address here:
https://openathens.nice.org.uk/
Library Opening Times
Staffed times 8.00 am—17.00 pm
Monday to Friday
Swipe Access 7.00 am—23.00pm
7 days a week
Level 5,
Education Centre
University Hospitals Bristol
Contact your outreach librarian @