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INTRODUCTION

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GERD cases recorded in Amang

Rodriguez Medical Center

Year Gerd Cases Reported

2010 5

2011 1

2012 3

2013 1

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GERD cases recorded in Jose Reyes

Memorial Medical CenterYear Gerd Cases Reported

2011 7

2012 3

2013 5

Age Range Cases Reported

0-10 2

11-20 3

21-40 4

41-60 2

61-80 3

Sex Cases Reported

Female 4

Male 11

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PATHOGENESIS OF GERDMafe Cabiles

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Gastric Acid Production

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Among the mechanisms thought to contribute

to the development of GERD are

Decreased LES restingtone

the normal LES pressuremust be higher than the

gastric pressure Impaired Esophageal Acid

Clearance

Delayed Gastric

Emptying or GastroParesis

Decreased Salivation

Impaired Tissue Resistance

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Pathological

VS.

NormalBea Antonio

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Normal Esophagus

Covered with non-keratinized squamous

epithelium

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Barretts Esophagus The squamous epithelium is replaced with goblet cells, called intestinal metaplasia.

Columnar Epithelia

Major risk factor of GERD

About 1 out of 10 patients with GERD are found to have Barretts Esophagus.

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Alyzza KhimberlyVergara

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Heart burn and acid

regurgitation Dysphagia and

Odynophagia

Non-cardiac chest pain

Extraesophagealsymptoms

Symptom relapse andchronicity

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Antacids that neutralize stomach acid

Prescription-strength medications

Surgery and other procedures used ifmedications don't help.

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Bianca Dela Cruz

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Conclusion:

The pathophysiology of GERD is clearlymultifactorial, despite the many medicalintervention available in the medical field does

not in any way alleviate this disease entirely. Successful treatment of GERD in patients whose

symptoms are poorly controlled with medicaltreatment remains a challenge. GERD remains a

significant clinical problem. A number of majorquestions remain unstudied or, as yet,unanswered.

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References Esophagus: Barrett's esophagus, dysplasia and adenocarcinoma. (n.d.).

Retrieved fromhttp://atlasgeneticsoncology.org/Tumors/BarrettsEsophagID5591.html

Barrett's Esophagus - National Digestive Diseases Information

Clearinghouse. (n.d.). Retrieved from

http://digestive.niddk.nih.gov/ddiseases/pubs/barretts/

Ways to Increase Stomach Acid Production [Video file]. (n.d.). Retrievedfrom http://www.branchbasics.com/learn/ways-to-increase-stomach-acid-

production/

Acid Production in stomach_1.flv [Video file]. (n.d.). Retrieved from

http://www.youtube.com/watch?v=Wvpz9m92ZQA

Developments in pathogenesis and diagnosis of gastroesophageal refluxdisease [Video file]. (n.d.). Retrieved from

http://cat.inist.fr/?aModele=afficheN&cpsidt=18800524

[Video file]Retrieved from

http://www.cedrugstorenews.com/userapp//lessons/page_view_ui.cfm?l

essonuid=&pageid=20E9006810884CADCC67B1249653D55F