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8/11/2019 GI Summer Review -Answers- Bosch (2013)
1/16
8/11/2019 GI Summer Review -Answers- Bosch (2013)
2/16
2013
Gl
Summer
Review;
Barbara
D
Bosch.
M D page 2
A
34 year-old
man comes
to
the emergency
department
complaining
of the
sudden onset of
vomiting
an d epigastric
abdominal
pain
radiating
to
the
back.
On
physical
examination,
the patient is
afebrile
and has abdominal
tenderness;
decreased bowel sounds are
noted,
as is
diffuse bruising that
he
describes as
having appeared suddenly. He
also reports continuous
epistaxis.
Laboratory tests
show
a slightly
elevated
WBC
count,
thrombocytopenia,
increased
amylase an d
lipase activity,
increased
prothrombin time
(PT)
an d
partial
thromboplastin
time (PTT), and the presence
of fibrin split products.
An
abdominal
ultrasound
performed
at
the
bedside
shows a
dilated common bile
duc t. Wh ich
of the
following
is the
most likely etiology of
this
patient's
abnormal
coagulation
profile?
A. abdominal aortic
aneurysm
meag+ \
,
20?
acute pancreatitis
Vv
*
y*
*
C.
appendicitis
FK?*>
.
V
?
\
'
,*
D. gastric
ulcer
\
2
'*>
.*,
W
E.
gram-negative sepsis
boA
Jf?
In the
H&E-stained
photomicrograph, the
arrow points
to which o f the
following specific
structures?
central
(hepatic)
vein
hepatic artery
5?
portal
vein
D.
sinusoid
E.
space of Disse
On
the
da y
of the
BaL*aaBrcafcQn-in
pathology,
a 26 year-old medical student notices that he r
sclerae have a
sfightyellowish
color.
She ha s never
ha d
a major illness. On physical exam,
there
are
no
significant
findings other than the
mild scleral icterus.
Laboratory studies
revea l a total bilirubin
of
4.9 mg/dL
(normal
0.1-1.0
mg/dL)
with a
direct
bilirubin of 0.8
mg/dL (normal
0.0-0.3
mg/dL). The
scleral icterus resolves within
2
days. Which
of
the following conditions
is
most
likely
to produce
these
findings?
IV
/
A.
acute
hepatitis
A
virus
infection
y
\
B.
Dubin-Johnson
syndrome
hST
& n
tQ)
Gilbert
syndrome
T*
D.
ingestion of acetaminophen
-
o>
A
60
year-old
woman presents to
the
physician
with
painlesy?eddish-brown
blood
in
heTstooT)
Initial
laboratory
tests show
the
following
results:
hematocrit:
33%
(normal
36-46%)
hemoglobin:
11
g/d
L
(normal
12-16
g/dL)
mean corpuscular volume: 73
pm 3
(normal
80-100
pm3)
white blood
cell count:
8,000/mm3
(normal
4,500-1
1
,000/mm3)
platelet
count:
200,
000/mm3
(normal
150,
000-400,
000/mm3)
Which of
the following
is
the
most
important next
step
in
the
management
of
this
patient?
A.
abdominal plain
films
colonoscopy
C.
CT scan of
the abdomen
D.
esophagoduodenoscopy
E.
pelvic
ultrasound
A patient
presents to
the
emergency
room
withTpper
Gl
bleeding
Administration
of
an agonist/
analog
of
which of the
following agents
would inhibit
gastric,
ar.id
spr.rpfinn?
*
/K.
acetylcholine
gastrin
-6T
histamine
pepsin
somatostatin
i
8/11/2019 GI Summer Review -Answers- Bosch (2013)
3/16
2013
Gl
Summer
Review;
Barbara
D.
Bosch, M.D.
page
3
A2year-olchild
presents
with_a
history
ofeonataT
)7nchT
UJ1CV
_
_
_
_ _
as
well
as
aQhronic
cougand
SluincgFironirdiafrhea
frjthliqhlcolored
Joul-smelling
stools.
A
deTiciency
of
which
of
the
following
vitamins could
develop?
A. ascorbic
acid
B. folate
C.
niacin
retinolCvi*
Ay
E.
riboflavin
F.
thiamine
d\
~
C-Vk-oAWLXj*
You recommend a
colonoscopy to
a
50
year-old
patient.
He agrees, bu t
wants
you
to
describe
the
procedure
an d
potential
risks and
complications.
You
explain
that the goal of
the
procedure
is to
look
at
the
entire length
of the
large
intestine with
a
flexible
fiberoptic colonoscope
and
to biopsy
any
observable lesions.
You tell him that
there
is
a small risk of perforating the
bowel,
especially
when
the
colon takes a sudden turn or
twists
on itself
at
regions
where
it
is
intraperitoneal
rather
than attached
to the
posterior
abdominal
wall
(retroperitoneal). With your
knowledge
of
anatomy,
which
of
the
following regions
of the large
intestine pose
the
greatest
risk for
perforation
to
the
gastroenterologist?
A . a sc en din g
colon,
transverse colon and descending colon
B.
descending
colon,
sigmoid
colon an d
rectum
yC>
hepatic
flexure,
splenic
flexure
and
sigmoid
colon
D.
hepatic
flexure,
transverse colon and
splenic
flexure
E. splenic
flexure,
descending
colon
an d sigmoid
colon
A
hepatitis panel
is
ordered
for a
27
year-old
woman as
part
of a routine workup for
abdominal
pain.
Results
of serologic testing
are negative
for HBeAg
an d
HBsAg,
bu t
positive
for
HBsAb and
IgG
HBcAb.
Which
of the following is the
appropriate
conclusion?
The
patient
has been
exposed
to
hepatitis
B
and has
completely
recovered.
B.
The
patient
has
been
exposed
to
hepatitis
B
an d is
in
the acute disease
phase.
C.
The
patient
has been
exposed
to
hepatitis
B
an d
is in
the window
phase.
D.
The
patient
ha s
been
exposed
to
hepatitis B
bu t was not
infected.
E.
Th e
patient
has been
exposed
to
hepatitis
B
and is now chronically
infected.
F.
The
patient
ha s been successfully vaccinated for
hepatitis
B.
An
overweight, 46 year-old
man has complained
of heartburn
for the
past
is
pr
ears.
A photomicrograph from
a
biopsy
of
his lower esophagus
vided. Which of
the
following
is
the most likely diagnosis?
f
Barrett
esophagus
Candida esophagitis
C.
herpes
esophagitis
D.
Plummer-Vinson syndrome
E.
viral
esophagitis
A
67 year-old woman
has
experienced
severe
nausea,
vomiting,
early
satiety,
and
a
9-kg weight
loss over the
past
4
months.
On
physical
examination,
she ha s mild muscle wasting.
Upper gastrointestinal
endoscopy shows
that
the
entire gastric
mucosa is eroded
and erythematous.
Upper
gastrointestinal
imaging
studies reveal that the
stomach is
small
and shrunken.
Which
of
the following
is most
likely
to
tie
founon
histologic
examination of a gastric biopsy
specimen?
jlffi
chronic
atrophic
gastritis
B.
granulomatous
inflammation
t
Q
C.
intestinal-type
adenocarcinoma
.
parietal
cell hyperplasia
T
V\r~*
0
signet-ring cell
adenocarcinoma,
8/11/2019 GI Summer Review -Answers- Bosch (2013)
4/16
2013
Gl
Summer
Review;
Barbara
D.
Bosch,
M.D.
page
4
Which
one o f
the
following is
most likely to be
present
within
the
smooth
endoplasmic reticulum
of
hepatocytes?
v
--
.
albumin
cholesterol
_
C. fibrinogen
D.
glycogen
* ~'a
E.
hydrogen peroxide
-
lpcowitPWck
t-Jr v\
hemolytic
anemia
I
~
pancreatic
carcinoma
lv
I
8/11/2019 GI Summer Review -Answers- Bosch (2013)
5/16
2013
Gl
Summer Review; Barbara
D.
Bosch,
M.D.
page 5
In
the
accompanying photomicrograph
of an H&E-stained
tissue
section,
the
structures
indicated
by
arrows are which
of
the
following?
A.
clusters
of hepatocytes
B.
intralobular ducts
C
islets
of Langerhans
D.
parasympathetic
ganglia
E.
serous acini
A
19 year-old woman is
bothered
by
8/11/2019 GI Summer Review -Answers- Bosch (2013)
6/16
2013 Gl Summer
Review;
Barbara D.
Bosch,
M.D. page
6
A
45
year-old
woman
presents
with intermittent
episodes
of
epigastric
pain
an d
is found to have
gallstones
on ultrasound. However,
she
is no t
jaundiced. During
exploratory surgery, one stone
is
found to be
obstructing
a
duct.
In
view of her
symptoms,
where is the most
probable
location of the
obstruction?
A. ampulla
of
\Zater~~p >
0
C.
common
heoatic duct
.
common
hepatic
duct
D.
cystic duct
-t>duct
of
Santorini
--
x-rn
Over the
past 3
months, a
41 year-old man ha s
noticed that h is
skin
has
become progressively
more
ye llo w. O n physical exam,
he
is afebrile
but has scleral icterus and
generalized
jaundice.
Laboratory
studies show
a
total
serum
bilirubin
of 8.9 mg/dL
(normal
0.1-1.0
mg/dL)
with
a
direct bilirubin of 6.8
mg/dL
(normal
0.0-0.3
mg/dL).
Serum
ALT
and AST levels
are
normal.
A l iver biopsy
shows
histologic features
of sclerosing cholangitis.
Which
of
the following
diseases
is
most
likely
to coexist
with the liver
disease?
A. celiac
sprue
B.
chronic pancreatitis
C.
Crohn
disease
D.
diverticulosis
ulcerative colitis
A
22
year-old
woman
ha s
ha d several
episodes of aspiration
of food
associated with
difficulty
swallowing
during the
past
year. A barium swallow shows markeoreiobhaaeal
dilation
abovS
the
leybl
of
thedower
esophageal
sphincteft
A
biopsy specimen
from the lower esophagus shows an
sence
of
the
mventprir.
gangTlgfTATHat
js
the
most
likely diagnosis?
achalasia
B.
Barrett
esophagus
C.
Boerhaave
syndrome
D.
Plummer-Vinson
syndrome
E.
Schatzki
ring
A
55
year-old
man presents
with general ized back
pain. X-ray
examination
o f the
spine reveals two wedged thoracic vertebrae,
T7
and T8.
He
is found to
be anemic
with a
normal
peripheral
blood smear. However,
examination of
his bone marrow
shows
an
increased
number of
the
type
of
cells indicated
by
arrows
in
this
photomicrograph of
the
small intestine.
These cells
synthesize
which
of the
following?
collagen
B.
heparin
and histamine
C. his taminase
(> IgA
E.
myeloperoxidase
A 3 week-old bo y
presents
to
his pediatrician because
his
mother has noticed
that
he
looks yellow .
On
questioning, she elaborates that
the
jaundice
began several days
after
birth and has been
associated with
dark
urine and
acholic stools. Laboratory studies
show
a
direct
bilirubin
leve l o f 5 .0
mg/dL
(normal
0.0-0.3 mg/dL) and
a
total bilirubin
level of 5.5 mg/dL
(normal
0.1-1.0
mg/dL).
Which
of
the
following
is the most likely diagnosis?
\oMt\ihK\
jQ/
8/11/2019 GI Summer Review -Answers- Bosch (2013)
7/16
2013
Gl Summer
Review; Barbara D.
Bosch,
M.D.
page
7
A 25
year-old
man with
acquired
immunodeficiency disease (AIDS)
has
malabsorption,
chronic
abdominal
pain,
low-grade
fever,
and
nonbloody diarrhea.
In
fecal
smears,
large
numbers
of oocysts
containing
four
sporozoites
are
observed.
Which
of the following
organisms
is
the
most
likely
etiologic
agent?
Cryptosporidium
parrum
/ B.
Entamoeba histolytica
j
C. Giardia lamblia
\J
D.
Taenia
solium
E.
Toxoplasma
gondii
A
30
year-old
woman sees he r physician
because she
has had
diarrhea
an d
fatigue,
as
well
as a 3-kg
weight
loss over
the
past
6 months.
On
physical
examination,
sh e
is afebrile
and has
mild muscle
wasting,
but
her
motor
strength
is normal. Laboratory studies show no occult
blood,
ova
or
parasites
in the
stool.
A biopsy
specimen
from
the upper jejunum
is
obtained. The
patient
is
placed
on a
special
diet with
no wheat
or
rye
grain
products.
This
dietary
change produces
dramatic
improvement.
Which of
the following
microscopic
features was most likely seen on
the
biopsy
specimen?
A.
crypt
abscesses
/
B. foamy macrophages within the lamina
propria
I
/
C. lymphatic
obstruction
\y
D.
non-necrotizing
granulomas
villous
blunting
an d flattening
A
26
year-old
man
has
recently aten
raw
oystersjon
three
occasions1
The
patient
ha s
always
been
healthy,
but now
has the
sudden onset of
fatigue,
loss of
appetite,
nausea,
vomiting,
abdominal
pain,
and fever. Which o f the following viral
pathogens
is
most likely
responsible
for
this
clinical
Presen,aj9~s
/ff
hepatitis B
virus
rotavirus
A
63
year-old man
who
had worsening congestive
heart
failure with
cardiac
dysrhythmias in
the last
year of
his
life
died
of
pneumonia.
At
autopsy,
his
pancreas
is small an d hard.
Microscopic
examination shows
extensive
atrophy
of the
acini with abundant
collagenous interstitial
fibrosis,
but
the
islets
of Langerhans
appear
normal.
Inspissated
proteinaceous
secretions
are
present
in
branches
of the
pancreatic
duct.
The
heart
weighs
500
g
(normal
300-350 g),
and
al l four chambers
are dila ted. What
condition is
most
likely to
account for
these
findings?
blunt trauma to the abdomen
B.
cholelithiasis
t
chronic alcoholism
diabetes melli tus
E. hypercholesterolemia
A 42
year-old
woman
has to
undergo(emergency
choiecystecto
fo
du e
to
intense
surgery is indie
wing
arrows?
$
\
.
3
/L
T 4
5
'he
structure to
be
removed during
Accompanying radiograph
by
which of the
8/11/2019 GI Summer Review -Answers- Bosch (2013)
8/16
2013
Gl
Summer
Review;
Barbara D
Bosch,
M .D. page
8
A
full-term
neonate
presents to the
pediatrician
with failure
to
pass
meconium.
Digital examination
of
the rectum
results
in
a gush
of retained fecal material.
Which of
the
following is the most
likely
diagnosis
in
this infant?
carcinoma of the colon
Chagas
disease
Hirschprung
disease
imperforate
anus
necrotizing
enterocolitis
of
Plasma
The figure to the
right sh ows a
gastric
parietal
cell with
selected
membrane transporters and
channels.
What
do
X,
Y and Z
represent?
Y Z
IT K+
K* IT
CI'
hco3-
Na+
IT
IT K+
Prlliptrjt
lll
HCO-s
atr
Lume
C. H
D. K+
E. Na+
The
symptoms
of
thiamine
deficiency
were
first
described
over 4000
years ago. In adults,
these
symptoms
commonly
include
polyneuropathy
of the
distal extremities,
resulting
in
paresthesias and
motor dysfunction.
In
addition
to neuropathy,
how
else can
isolated
thiamine
deficiency
present
in
adults?
A.
chronic infections
.
.
diarrhea,
dermatitis
an d dementia
C.
Tjerirritability,
seizures and
jaundice
peripheral
edema an d congestive
heart
failure
E.
renal
failure
An obese
43
year-old white woman
presents to
the
emergency
department
with
right upper
quadrant
pain,
fever and jaundice.
Abdominal
examination
reveals
right
upper
quadrant
tenderness
without
peritoneal signs.
Endoscopic
retrograde
cholangiopancreatography shows several stones
in the
common
bile duct. Laboratory testing reveals a
WBC
count of
14,200/mm3
(normal
4,500-
11
,000/mm3),
with
74% segmented
neutrophils,
and a serum amylase level
of 78 U/L
(normal
25-125
U/L).
Which
of
the
following is the most likely
diagnosis for
this patient?
A.
acute
appendicitis
acute
pancreatitis
acute
viral
hepatitis
bacterial
cholangitis
cholesterolosis
.
Recanalization
of
the bile duct
after
the 13th week
of
development
allows
for
bile
produced
in
the liver
to
reach the
duodenum.
However*juM
C.
midgut
D. yfJIeuroperitoneal
membrane
/septum
transversum
5>
I
8/11/2019 GI Summer Review -Answers- Bosch (2013)
9/16
2013 Gl Summer
Review;
Barbara D.
Bosch, M.D.
page 9
A 36
year-old
woman is
in
the sixth month
of
he r
pregnancy,
but she
is
unsure
of
her
dates
because
she
was taking
oral
contraceptives
at
the
time sh e became
pregnant.
She
experiences
the
sudden
onset of severe
abdominal
pain.
On
physical
exam,
she is afebrile
an d
normotensive.
There is right
upper
quadrant
tenderness on
palpation.
An ult rasound scan of
the abdomen shows
a
well-
circumscribed,
7-cm
subcapsular
hepatic
mass. Paracentesis
yields
bloody fluid. At
surgery,
the
mass
in
the
liver,
which has
ruptured
through
the
capsule,
is
removed. The
remaining
liver
appears
unremarkable.
Which
of
the following is
the
most
likely diagnosis?
cholangiocarcinoma*
3
fibrolamellar
hepatocellular
carcinoma
epatic
adenoma
osa
hepatocellular
carcinoma
metastatic
carcinoma
testae.,
\
VvesfcH
I
C\r
A
32
year-old
man
presents
with diarrhea
and
symptoms
of
peptic
ulcer disease. Endoscopy reveals
two
ulcers,
one
in
the first
portion
of the duodenum and one in
the
mid-duodenum.
However,
they
do
not
respond
to the usual
peptic
ulcer
treatment programs.
The
most likely
explanation
for
the findings
in
this
patient
is which of
the following?
-autoantibodies
to
intrinsic
factor
ectopic
hypersecretion
of gastrin
gastric mucosal
atroohv
_
c.il
Menetrier disease
pressure
ulceration from
y.
vascular
abnormality
A pathologist views the tissues
in
the
accompanying photomicrographs
in
a
biopsy
specimen.
She determines that
the tissues are
normal. The
presence
of
both of these
tissues indicates
that
the
sample
was
taken from
the
region
of the
junction between
which of the
following?
Ar mouth
and
esophagus
/
esophagus
and
stomach
itomach
and duodenum
Ileum
an d colon
rectum an d anus
A
Syarlold
manjresents
to the
clinic with
ffieral
icterusipatosplenomegaly$|scites>and
a
history
of
episodes
of
feundice
over'the oast
th'fgg vear&7
He
was involved
in
an
auto
accident
when
A
LTrVteT
he
was
21,
fo r which he
req
u
i
re
8/11/2019 GI Summer Review -Answers- Bosch (2013)
10/16
8/11/2019 GI Summer Review -Answers- Bosch (2013)
11/16
2013
Gl
Summer
Review;
Barbara
D.
Bosch, M.D. page 11
A 56
year-old man
who is a health care
worker
presents
to his
physician
with
vague
abdominal
discomfort.
A
physical
examination reveals a tender
liver,
palpable
to
6
cm
below
the
costal
margin,
and
scleral icterus. His laboratory
studies are significant
for
an
aspartate
aminotransferase (AST)
level
of
20 0 U/L
(normal
8-20
U/L),
an
alanine
aminotransferase
(ALT)
level
of
450 U/L
(normal
8-20
U/L),
an d an alkaline
phosphatase
level of 24 5
U/L
(normal
20-70
U/L).
A
CT scan
of the abdomen
shows a dominant solid
nodule
in
the liver. The tumor
marker
mjst
likely to be
elevated
in
this patient
is
also
agobd
indicator
of
which
of the
following malignancies?
Sh.
choriocarcinoma
.
//
colorectal carcinoma
clSK
SCuroZstoma
QtU,
prostatic
carcinoma
-V-n
n
.
Vo,k
sac
tUmor
yf
A
28 year-old
recently
divorced man with
no significant
past
medical history
presents
with progressive
lower
abdominal
pain
and cramping over
the
past
4
days,
which are
relieved
by
defecation.
He
has
uVir
suffered
from
substantigkgTooand
mucoid
diarrhea\jiring
th'g
time.
His
temperature
is
Lab
studies
reveal
arylevited
WBC
courSt
and'tgiTerythrocyte
sedimentation
Sigmoidoscopy
reveaWextensrveTectaTand sigmoid hyperemia
aTid
edema,
numerous
superficial
ulcerations,
an d
small focal mucosal
hemorrhages, many
of which have
suppurative
centers. These
B.
Crohn disease
C.
cytomegalovirus
enterocolitis
hP&
9*0
A
pseudomembranous
colitis
-erative
colitis
A
30
year-old
man seeks
help
because
heJ]tesLiLrfeels(full
afterating55lcsmal>
8/11/2019 GI Summer Review -Answers- Bosch (2013)
12/16
2013 Gl Summer Review;
Barbara
D.
Bosch.
M.D.
page
12
A 39 year-old woman
presents
with
dyspnea,
fatigue,
pallor,
and
tachy
cardia.
Laboratory results reveal
a
hematocrit of
32 %
(normal
36-44%),
a red cell mean
corpuscular
volume of
102
fL (normal
78-98
fL),
and a
vitamin
B12
level of
95
pg/mL (normal
200-900
pg/mL) due to impaired
absorption.
Autoantibodies are
detected
to a cell
type
which
produces
intrinsic
factor.
Referring
to the
accompanying
diagram,
in
which
region
woulft
those
cells be
found?
V
A 44 year-old
woman
has noticed
increasingly
severe
fatigue
an d generalized
pruritus
for
the past
8
months. Serum levels
of
alkaline
phosphatase
and cholesterol are elevated;
antimitochondrial
antibody titer
is
elevated, bu t
ANAs are
no t present.
The
serum
total
bilirubin
concentration
is
slightly
elevated.
A
l iver biopsy
is
performed
revealing granulomatous
destruction of
small
intrahepatic
bile
ducts.
Which
of
the
following
conditions
is most
likely?
_
A.
autoimmune
hepatitis
B.
choledocholithiasis
'n.rve'W.r.oA
ft*
C.
hepatitis B
primary biliary
cirrhosis
E. primary sclerosing
cholangitis
F.
Wilson
disease
w
VA
A
66
year-old
man
presents with
a 3-month
history of intermittent
dysphagia
that ha s
now
become
constant
an d
is
accompanied
by
pain and
weight
loss.
X-rays
of
the
esophagus
with barium
swallow
show
structural and
filling defects,
and reduced
peristalsis.
A
biopsy is
taken, f rom which
a
representative
photomicrograph
is
provided.
The
best
diagnosis
is which of the
following?
fd'
adenocarcinomaCTT0*9
-
BrBarrett
esophagus
~
Candida
esophagitis
fibrous
stricture
8/11/2019 GI Summer Review -Answers- Bosch (2013)
13/16
2013
Gl
Summer
Review;
Barbara
D.
Bosch,
M.D. page
13
inaseVsefes
-
**#*&*
>,&
1>.
.
J
.
v Iv
r- '
r
-
C-Jysozyme
mucus
an d
HCOV
pepsinogen
A
52
year-old
woman is
referred to
a
gastroenterologist
for
persistent
abdominal
is
performed.
of normal
tissue
structures
A.
B.
enterokina;
An 1
8
year-old
woman
presents
with
a
one-week history
of
fever
an d
malaise>She
has
mild
jaundice
and a
(ffightly
Hemoglobin
is
13.8 g/dL
(normaM3M(fg/dL);
WBC count is
13,000/mm
(normal
4,500-1
1,000/mm3).
SeruiTLJubinJs
mg/dL
(normal
0.1-1.0
mg/dl_)
an d is 95% unconjugated
bilirubinLiver
enzyme
tests
arenona
Which
of
the following
is
the most likely cause
of this
patient's
signs
an d
symptoms?
jC
alcohol
abuse
c\
decreased
glucuronyl
transferase
hemolysis
8/11/2019 GI Summer Review -Answers- Bosch (2013)
14/16
2013 Gl Summer
Review;
Barbara
D
Bosch,
M.D page 14
Jaundice caused
by common
bile
duct obstruction is usually
characterized
by
which o f the
following
laboratory
findings?
Urine Urine
Bilirubin Urobilinogen
A.
t
B. T
-gP
T
D.
Normal
E.
Normal
F.
Normal
T
Normal
1
t
Normal
i
A
13
month-old child is brought to
the emergency department
after
his
parents
found blood
in his
stool.
They
state
that
he did
no t
appear
distressed
at the time,
although
he
now displays
some
tenderness
to
abdominal
pressure.
Other
than
this
tenderness,
there
are
no significant findings
on
physical
examination. After performing
radionuclide imaging using
mTc
pertechnetate,
the
doctor
makes a d iagnos is and
recommends
surgery
to correct the problem. What
is
the probable source of
this child's
condition?
A.
blockage of the intestine
du e
to folding
of the
distal ileum into the
proximal
colon
B. breakdown of
the gastric
mucosal
barrier with
erosion
of
the
underlying
mucosa
damage
to the
intestinal
epithelium
due to ingestion of
coins
ectopic
gastric
epithelium
in a
persistent omphalomesenteric
duct
E.
incomplete bowel
rotation
resulting
in obstruction of
the
superior
mesenteric artery
A 2
year-old girl
with
a
lifelong
history of malabsorptive
an d
foul-
smell ing diarrhea,
weakness an d
general
failure
to thrive
has
just
undergone
a sma ll
intestine biopsy
(see
accompanying
photomicro
graph).
Her
parents
believe
her problems began
at 6 months of
age,
when
she
started
eating
solid
foods, but have significantly
worsened
over
the
past few
months.
The only recent
change in her
diet
is
that she
eats a
bowl o f cereal
every
morning
with
her parents
before
they
go
to work.
Sh e
tried a dairy-free
diet
a
month
ago,
bu t
it did not improve
her
symptoms.
Which
of
the
following
js
the
likely
diagnosis?
/yA.
abetalipoproteinemia
/
>.
celiac
disease
cystic fibrosis
pQ-
lactase
deficiency
viral
enteritis
F/Vhipple
disease
1
'mmm
'
'MS
s :v
8/11/2019 GI Summer Review -Answers- Bosch (2013)
15/16
2013
Gl Summer
Review;
Barbara D. Bosch,
M.D.
page
15
A
healthy volunteer received a
continuous
infusion
of physiological
gastrin
concentrations before an d after treatment
with
peptide X.
The
production
of
gastric
acid an d
pancreatic
bicarbonate
secretion
was
monitored before an d after administration of
peptide
X
(at
arrow).
Peptide X
is
most likely to
have been which
of
the
following
hormones?
angiotensin
II
cholecystokinin
motilin
secretin
somatostatin
Last':
=sf;i
Js i
FfcMhc
HCDj
B.
C.
E.
aarc*Mlc
HZO
unrc
H
I r~
i
l
Qutotfl :
8/11/2019 GI Summer Review -Answers- Bosch (2013)
16/16
2013 Gl Summer
Review;
Barbara
D.
Bosch,
M.D.
page
16
A 23
year-old
man
has been
complaining
of
intermittent
diarrhea,
fever and
abdominal pain for
several
months. A radiograph
of
the
small
bowel
reveals
several
separatg_areas
of
luminal
narrowing.
A
photomicrograph
of this
patienVCiieal
bfopsy
is shown.
What
is
the
most
likely
diagnosis?
-r
abetalipoproteinemia
tvlvAvH
carcinoid
tumor
A.
B.
E.
F.
celiac disease
Crohn
disease
ulcerative
colitis
Whipple
disease
,r>;
/'
l
r
.