giovanna viale_nyex2011

NYEX 2011 Conference, 13-16 March Judea, Israel

TALENTED STUDENTS AND MOTIVATED TEACHERS: AN INTERACTIVE AND SYNERGISTIC TANDEM TO

DESIGN INNOVATIVE HANDS-ON LEARNING PRACTICES IN BIOLOGY

Giovanna Viale and Cinzia GrazioliCusMiBio, Milan – Italy



Study groups

Hands-on

activities

Tutorials

Sharing of experiences Accountable sources

Continuous education

Suggestions forIBSE

CUSMIBIO FOR SCIENCE TEACHERS

•filling the GAP•recover motivation & social role

Internationalcontacts


CUSMIBIO FOR HIGH SCHOOL STUDENTS

•for a future in science

a dream-postcard from Cambridge


OPPORTUNITIES FOR TALENTED YOUNG PEOPLE IN BIOSCIENCES

Promote students’ investigation experiences

...I’m not so sure!!!

Can I have a look too ?


CUSMIBIO“FROM MANY TO FEW”

An opportunity for all students. Reach the largest possible number of

students attending all types of high schools

A challenge for the most talented.Selected actions envisaged for the most gifted students



An opportunity for all students.




CUSMIBIO HAS DEDICATED LABS IN THE MILAN STATE UNIVERSITY CAMPUS

These labs are an integral part of the Lombardy school system


CusMiBio activities are funded by UniMi (University of Milan),

USR (Educational Office of Lombardy), MIUR (Italian Ministry of University and Research).

Lab costs are partly covered by students’ fees.

Unfortunately no EC funds yet


Since 2009 CusMiBio has been appointed by the Italian Ministry of Education as reference

centre for the valorization of talented High School students

Selected actions envisaged for the most gifted studentsA WEEK AS A RESEARCHER



HOW TO INVOLVE TALENTED STUDENTS IN NEW INITIATIVES?

1.WANNABE A RESEARCHER: ATTEND A TOP SCIENCE PROJECT

2.FROM SCHOOL to UNIVERSITY: A ROUND TRIP


RESULTSThe project greatly excited all the students involved and also their school teachers!The results obtained were published in a Science and Society correspondence in EMBO Reports (EMBO Reports 9, 3, 208–211, 2008).

WANNABE A RESEARCHER: ATTEND A TOP SCIENCE PROJECT •to keep tight contacts with the talented students selected through the annual contests•to combine professional quality research with a novel strategy for research-based undergraduate education


From CusMiBio to SchoolKits (materials, handbook, protocols, teacher guide etc..)

that can be “hired” from CusMiBio and taken to school.

FROM SCHOOL TO UNIVERSITY: A ROUND TRIP

From School to CusMiBioTry the biolab: hands-on activities for High School students at the CusMiBio Laboratories


AN INTERACTIVE AND SYNERGISTIC TANDEMTO DESIGN INNOVATIVE HANDS-ON LEARNING PRACTICES

IN BIOLOGY The most motivated and skilled students, identified through selective competitions, are invited together with their teachers

to set-up KITS and learning modules adapted to be transferred to their schools.

Both are actors of the project. Together they develop the theoretical and practical

activities to be proposed to their peers

A positive reciprocal feedback


Using peer-to-peer teaching: •Engages students and inspires their peers•Helps students motivate each other to delve deeper into science•Talented students returning to their schools share their knowledge with fellow students through a combination of experiments and dialogue

This approach facilitates productive interactions and dialogue within peers and can break the intimidating “teacher-student” barrier

FROM SCHOOL to UNIVERSITY: A ROUND TRIP

RESULTS: Students (1)


‘learning by teaching’ strategy: you learn a lot when you have to

teach others


students’ own knowledge and confidence grows as they pass on their knowledge and experiences


Moreover…students have an opportunity to develop a wide range of complementary skills, such as work in groups, peer exchange abilities, communication with an appropriate language

whether the students taught by the tutors benefit is yet to be evaluated.


RESULTS: Students (2)


•acquisition of additional knowledge to manage the topics with the required competence• •design of Lab activities suitable for being performed at school

•creation of the most favorable conditions for cooperation within and between schools• •exchange of materials and experiences.


RESULTS: Teachers

CusMiBio

PILOTSCHOOL

PILOTSCHOOL


This project needs the

teachers’

contribution for:

•the identification of pilot schools (provided with some kind of lab space and equipment) that can act as reference labs for all the schools of a given area •development of school networks

DEVELOPMENT OF SCHOOL NETWORKS


The collaboration starts during the training courses where the different stake-holders, i.e. scientists, student and their teachers come in close contact. Scientists have agreed to mentor classroom teachers and students through these courses.

TRAINING FOR TEACHERS AND THEIR STUDENTS

How to use the kits at school

WHO IS THE CULPRIT?WHO IS THE CULPRIT?


DNA PROFILING •constructing a real life crime scene investigation, collecting the evidence



•finding the incriminating evidence, through blood testing and DNA analysis to obtain molecular identikits for human genotypic identification.


FLASH GEL SYSTEM

5 min separation & recovery

…find the culprit

YEAST : HONORARY MAMMALYEAST : HONORARY MAMMAL


YEAST: HONORARY MAMMAL

•mating of yeast cells of opposite mating type and observe complementation

•selection of cell division cycle (cdc) mutants based on their temperature-sensitivity

•microscopic observation of Saccharomyces cells during cell division;


NB: All materials must be returned to CusMiBio. Mishandling, breakage or missing instruments costs will be borne by the school. All materials provided in the kit, if correctly handled, don’t pose risks and conform to safety standards. For further information, check the instructions in the kit.

EACH KIT COMES WITH THE LIST OF MATERIALS

CHROMOSOME ANALYSISCHROMOSOME ANALYSIS


CHROMOSOME ANALYSIS

•Microscope observation to compare human and mouse metaphase chromosomes;•cytogenetic analysis of human normal and pathological karyotypes.

FISHFISH


Fluorescent in situ hybridization

Magnetic bars + iron beads serving as probes!!

FISH is suitable for gene mapping and for the identification of small chromosomal aberrations involving a single gene, not visible by cytogenetics.


HOW TO IDENTIFY SPECIFIC GENES ON CHROMOSOMES?

HOW TO IDENTIFY SMALL CHROMOSOMAL ABERRATIONS INVOLVING SINGLE GENES?

The use of a model simulating FISH allows the students to acquire the basic principles of this technique and to appreciate its high resolution power.


Deletion of a small chromosome region

Fluorescent in situ hybridization (FISH)

Real FISH Simulated FISH

VIRTUAL MICROARRAYSVIRTUAL MICROARRAYS


RED LIGHT GENES

……… and NOT ONLY RED

VIRTUAL MICROARRAYS(Initially developed at EMBL-ELLS labs, Heidelberg)


VIRTUAL MICROARRAYS

To visualize gene expression a custom-made mat, Velcro and torches are used, following step by step the microarray technology and learning about its possible future applications.


This initiative •facilitates productive connections and synergies between High School and Research Universities

• provides a challenging and rewarding experience to talented students


Thank you!website: www.cusmibio.unimi.it

e-mail: [email protected]

http://www.cusmibio.unimi.it/






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