Glycolysis
The three steps
Glucose + 2Pi +2ADP +2NAD
2Pyruvate + 2ATP +2NADH +2H+ +2H2O
Glucose to Glucose 6 phosphate
Hexokinase
G6P to F6P
Phosphohexoseisomerase
Mg++
G’O=1.7 kJ/mol
G’o= -14.2 KJ/mol
F6P to F1,6, BP
F1,6BP to DHAP & G3P
G’O = 23.8kJ/mol
DHAP & GAP
GAP to 1,3-BPG
G’O = 6.3kJ/mol
1,3-BPG to 3-PG
G’O = -18.5kJ/mol
3’PG to 2’PG
Rearrangement shifts PO4 position from C3 to C2.
2PG to PEP
Enol PO4
PEP to Pyruvate
Thermodynamics
Uses of Pyruvate
Regeneration of NAD
Pyruvate to ethanol
Pyruvate to lactate
Recycling NAD
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Galactose
Glycogen to glucose (starvation)
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