Gnipst Bulletin 31.1

8/13/2019 Gnipst Bulletin 31.1

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13th

December , 2013 Volume No.: 31 Issue No.

Contents Message from GNIPS

Letter to the Editor News Update

Health awareness

Disease Outbreak Ne

Forth Coming Events

Drugs Update

Campus News

Students Section

Editors Note

Archive

Vision

TO GROW AS A CENTRE OF EXCELLENCE IN THE FIELD O

PHARMACEUTICAL AND BIOLOGICAL SCIENCE

EDITOR: Soumya BhattacharyaGURU NANAK INSTITUTE OF PHARMACEUTICAL SCIENCE AND

TECHNOLOGY

GNIPST Photo Gallery

For your comments/contributionORFor ack-Issues,

mailto:[email protected]
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Click here to go at the top

MESSAGE FROM GNIPSTGNIPST BULLETIN is the official publication of Guru Nanak

Institute of Pharmaceutical Science & Technology. All the members

of GNIPST are proud to publish the 31st Volume of GNIPSTBULLETIN. Over the last two years this bulletin updating readers

with different scientific, cultural or sports activities of this

prestigious institute and promoting knowledge of recent development

in Pharmaceutical and Biological Sciences. Students section is

informing readers about some curious facts of drug discovery, science,

sports and other relevant fields. We look forward to seeing your

submission and welcome comments and ideas you may have.

LETTER TO THE EDITOR.

NEWS UPDATE

Dietary Amino Acids Improve Sleep Problems in

Mice with Traumatic Brain Injury (11th

December, 2013)Scientists have discovered how to fix sleep disturbances in mice withtraumatic brain injuries, a discovery that could lead to help forhundreds of thousands of people who have long-term and debilitating

sleep and wakefulness issues after they suffer concussions. Read

more

Stimulant-Addicted Patients Can Quit Smoking

without Hindering Treatment(11thDecember, 2013)

Smokers who are addicted to cocaine or methamphetamine can quit

smoking while being treated for their stimulant addiction, without interfering

with stimulant addiction treatment. This is according to new research

funded by the National Institute on Drug Abuse (NIDA), part of the National

Institutes of Health.Read more

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More Powerful Approach to Analyze Melanoma's

Genetic Causes(11thDecember, 2013)There may be a better way to analyze the genetic causes of cutaneous

melanoma (CM) according to a study published in Human

Genetics conducted by researchers Yale and Dartmouth. A statistical

analysis using the natural and orthogonal interaction (NOIA) model showed

increased power over existing approaches for detecting genetic effects and

interactions whenRead more

Antiviral for HCV Improve Kidney, Cardiovascular

Diseases in Diabetic Patients(11thDecember, 2013)Researchers from Taiwan reveal that antiviral therapy for hepatitis Cvirus (HCV) improves kidney and cardiovascular outcomes for

patients with diabetes. Results of the study published in Hepatology,

a journal of the American Association for the Study of Liver Diseases,

show that incidents of kidney disease, stroke, and heart attack were

lower in patients treated with pegylated interferon and ribavirin

compared to HCV patients not treated with antivirals or diabeticpatients not infected with the virus.Read more

Researchers Find Shape-Shifting Stops Migrating

Cancer Cells(4thDecember, 2013)In research published in the December issue of Molecular and CellularBiology, investigators reveal how interplay of molecules keeps cancercells moving forward, and how disturbing the balance of these

proteins pushes their shape to change, stopping them in their tracks.Investigators say they have already identified a number of agents somealready used in the clinic for different disorders that may force shape-

shifting in tumor cells.Read more

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Newly Identified Brown Fat Stem Cells Hold

Possibilities for Treating Diabetes, Obesity (21stNovember, 2013)Obesity and diabetes have become a global epidemic leading to severecardiovascular disease. Researchers at the University of Utah believe

their recent identification of brown fat stem cells in adult humans

may lead to new treatments for heart and endocrine disorders,

according to a new study published in the peer-reviewed journal Stem

Cells.Read more

HEALTH AWARENESS

Dementia

Dementia is a syndrome usually of a chronic or progressive nature

in which there is deterioration in cognitive function (i.e. the ability toprocess thought) beyond what might be expected from normalageing. It affects memory, thinking, orientation, comprehension,calculation, learning capacity, language, and judgement.Consciousness is not affected. The impairment in cognitive function iscommonly accompanied, and occasionally preceded, by deteriorationin emotional control, social behaviour, or motivation.

Dementia is caused by a variety of diseases and injuries that primarily

or secondarily affect the brain, such as Alzheimer's disease or stroke.

Dementia is one of the major causes of disability and dependencyamong older people worldwide. It is overwhelming not only for thepeople who have it, but also for their caregivers and families. There isoften a lack of awareness and understanding of dementia, resulting instigmatization and barriers to diagnosis and care. The impact of

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dementia on caregivers, family and societies can be physical,psychological, social and economic.

Signs and symptoms

Dementia affects each person in a different way, depending upon theimpact of the disease and the persons personality before becoming ill.The signs and symptoms linked to dementia can be understood inthree stages.

Early stage: the early stage of dementia is often overlooked, becausethe onset is gradual. Common symptoms include:

forgetfulness losing track of the time becoming lost in familiar places.

Middle stage: as dementia progresses to the middle stage, the signsand symptoms become clearer and more restricting. These include:

becoming forgetful of recent events and people's names becoming lost at home having increasing difficulty with communication needing help with personal care experiencing behaviour changes, including wandering and repeated

questioning.

Late stage:the late stage of dementia is one of near total dependenceand inactivity. Memory disturbances are serious and the physicalsigns and symptoms become more obvious. Symptoms include:

becoming unaware of the time and place having difficulty recognizing relatives and friends having an increasing need for assisted self-care having difficulty walking experiencing behaviour changes that may escalate and include

aggression.

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Common forms

There are many different forms, or causes, of dementia. Alzheimer'sdisease is the most common form of dementia and may contribute to

6070% of cases. Other major forms include vascular dementia,dementia with Lewy bodies (abnormal aggregates of protein thatdevelop inside nerve cells), and a group of diseases that contribute tofrontotemporal dementia (degeneration of the frontal lobe of thebrain). The boundaries between different forms of dementia areindistinct and mixed forms often co-exist.

Rates of dementia

Worldwide, 35.6 million people have dementia, with just over half(58%) living in low- and middle-income countries. Every year, thereare 7.7 million new cases.

The estimated proportion of the general population aged 60 and overwith dementia at a given time is between 2 to 8 per 100 people.

The total number of people with dementia is projected to almostdouble every 20 years, to 65.7 million in 2030 and 115.4 million in2050. Much of this increase is attributable to the rising numbers ofpeople with dementia living in low- and middle-income countries.

Treatment and care

There is no treatment currently available to cure dementia or to alterits progressive course. Numerous new treatments are beinginvestigated in various stages of clinical trials.

Much can be, however, offered to support and improve the lives ofpeople with dementia and their caregivers and families. The principalgoals for dementia care are:

early diagnosis optimizing physical health, cognition, activity and well-being

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identifying and treating accompanying physical illness detecting and treating behavioural and psychological symptoms providing information and long-term support to caregivers.

Risk factors and prevention

Research identifying modifiable risk factors of dementia is scarce.Prevention focuses on targets suggested by available evidence, whichinclude countering risk factors for vascular disease, such as diabetes,midlife hypertension, midlife obesity, smoking and physical inactivity.

Social and economic impacts

Dementia has significant social and economic implications in terms ofdirect medical costs, direct social costs and the costs of informal care.In 2010, the total global societal costs of dementia was estimated to beUS$ 604 billion. This corresponds to 1.0% of the worldwide grossdomestic product (GDP), or 0.6% if only direct costs are considered.The total cost as a proportion of GDP varied from 0.24% in low-income countries to 1.24% in high-income countries.

Impact on families and caregivers

Dementia is overwhelming for the families of affected people and fortheir caregivers. Physical, emotional and economic pressures cancause great stress to families and caregivers, and support is requiredfrom the health, social, financial and legal systems.

Dementia is one of the priority conditions in the WHO Mental HealthGap Action Programme (mhGAP), which aims to scale up care for

mental, neurological and substance use disorders.(Based on WHO database)

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DISEASE OUTBREAK NEWS

Chikungunya in the French part of the Caribbean

isle of Saint Martin(11th December,2013)WHO was notified of two laboratory confirmed cases of locally

acquired chikungunya disease in the French part of the Caribbean isle

of Saint Martin. The other part of the isle is a country that is part of

the Kingdom of the Netherlands (Sint Maarten). These two cases

were confirmed by polymerase chain reaction (PCR) test performed

by the French National Reference Centre for arboviruses in Marseille.

Read more

FORTHCOMING EVENTS

The 2nd Pharm. Tech IAPST International Conference on "New insights into

diseases and recent therapeutic approaches"from 17th to 19th January 2014 in

Kolkata, India.Read more

DRUGS UPDATES

FDA approves first generic versions of

antidepressant drug Cymbalta (11thDecember, 2013)

The U.S. Food and Drug Administration today approved the first

generic versions of Cymbalta (duloxetine delayed-release capsules), a

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prescription medicine used to treat depression and other conditions.

Aurobindo Pharma Ltd., Dr. Reddys Laboratories Ltd., Lupin Ltd.,

Sun Pharma Global FZE, Teva Pharmaceuticals USA, and Torrent

Pharmaceuticals Ltd. have received FDA approval to market

duloxetine in various strengths.

Read more

CAMPUS NEWS

B.Pharm 3

rd

year won the GNIPST Football Champions trophy,2013. B.Pharm 3rdyear won the final match 1-0 against B.Pharm 2nd

year. Deep Chakrabortywas the only scorer of the final.

Students of GNIPST organized pre puja celebration programme,Saaranya on 7thOctober, 2013 in college Auditorium.

GNIPST organized a garment distribution programme on 28th

September, 2013 at Dakshineswar Kali Temple and Adyapith,Kolkata. On this remarkable event about hundred people have

received garments. More than hundred students and most of the

faculties participated on that day with lot of enthusiasm.

GNIPST celebrated World Heart Day (29th September) andPharmacists Day(25thSeptember) on 25thand 26thSeptember,

2013 in GNIPST Auditorium. A seminar on Violence againstwoman and female foeticide was held on GNIPST Auditorium on

25th September organized by JABALA Action Research

Organization. On 26thSeptember an intra-college Oral and Poster

presentation competition related to World Pharmacists day and

Heart day was held in GNIPST. Ms. Purbali Chakraborty of

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B.Pharm 4th year won the first prize in Oral Presentation. The

winner of Poster presentation was the group of Ms. Utsa Sinha,

Mr. Koushik Saha and Mr. Niladri Banerjee(B.Pharm 4thyear). A

good number of students have participated in both the competitionwith their valuable views.

STUDENTS SECTION

WHO CAN ANSWER FIRST????

Karplus, Levitt and Warshell won Nobel prize in

which discipline?

Franois Englert and Peter Higgs were awarded the

2013 Nobel Prize in Physics for the theory of how

particles acquire mass. In 1964, they proposed their

ideas independently of one another. When were their

ideas confirmed?

Answer of Previous Issues QuestionsA) Harald zur Hausen for his discovery of "human papilloma virusescausing cervical cancer"and the other half jointly toFranoise Barr-Sinoussi and Luc Montagnier for their discovery of "humanimmunodeficiency virus" B) Ritonavir

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Identify the place

Answer of Previous Issues ImageArthur Robert Ashe,(July 10, 1943 February 6, 1993)

was an American World No. 1 professional tennis player.

In the early 1980s, Ashe contracted HIV from a blood

transfusion he received during heart bypass surgery. He

founded the Arthur Ashe Foundation for the Defeat of

AIDS and the Arthur Ashe Institute for Urban Healthbefore his death from AIDS-related pneumonia on

February 6, 1993.Solve the Puzzle

3/8 *4/7*? =5376

Answer of Previous Issues Puzzle2

Send your thoughts/ Quiz/Puzzles/games/write-ups or any other contributions for Students Sectionanswers of this Section [email protected]

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EDITORS NOTE

I am proud to publish the 1st issue of 31st Volume of GNIPST

BULLETIN. GNIPST BULLETIN now connected globally

throughfacebook account GNIPST bulletin

I want to convey my thanks to all the GNIPST members and the

readers for their valuable comments, encouragement and supports.

I am thankful to Dr. Abhijit Sengupta, Director of GNIPST for

his valuable advice and encouragement. Special thanks to Dr.

Prerona Sahaand Mr. Debabrata Ghosh Dastidarfor their kindco-operation and technical supports. I am thankful to Mr. Subha

Bhattacharjee for his contribution tosolve the puzzle section .An

important part of the improvement of the bulletin is the

contribution of the readers. You are invited to send in your write

ups, notes, critiques or any kind of contribution for the

forthcoming special and regular issue.

ARCHIVE

Teachers daywas celebrated on 5thSeptember, 2013 by the

students of GNIPST in GNIPST Auditorium.

A zalea exotic flower ) , the fresher welcome programme fornewcomers of GNIPST in the session 2013-14 was held on 8th

August in GNIPST Auditorium.

One day seminar cum teachers development programme forschool teachers on the theme of Recent Trends of Life Sciences

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in Higher Education organized by GNIPST held on 29th June,

2013 at GNIPST auditorium. The programme was inaugurated by

Prof . Asit Guha, Director of JIS Group, Mr. U.S. Mukherjee, Dy

Director of JIS Group and Dr. Abhijit Sengupta, Director cumPrincipal of GNIPST with lamp lighting. The programme started

with an opening song performed by the B.Pharm students of this

institute. The seminar consists of a series of lectures, video

presentations and poster session. On the pre lunch session 4

lectures were given by Dr. Lopamudra Dutta, Mr. Debabrata

Ghosh Dastidar, Ms. Swati Nandy and Ms. Tamalika Chakraborty

respectively. On their presentation the speakers enlighten the

recent development of Pharmacy, Genetics and Microbiology andtheir correlation with Life Sciences. On the post lunch session, Ms.

Saini Setua and Ms. Sanchari Bhattacharjee explained the recent

development and career opportunities in Biotechnology and

Hospital Management. The programme was concluded with

valedictory session and certificate distribution.

About 50 Higher secondary school teachers from different

schools of Kolkata and North& South 24 Parganas district ofWest Bengal participated in this programme. A good interactive

session between participants and speakers was observed in the

seminar. The seminar was a great success with the effort of

faculties, staffs and students of our Institute. It was a unique

discussion platform for school teachers and professional of the

emerging and newer branches of Life Science.

The following B.Pharm. final year students have qualified, GPAT-

2013. We congratulate them all.

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The general body meeting of APTI, Bengal Branch has been

conducted at GNIPST on 15th June, 2012. The program started

with a nice presentation by Dr. Pulok Kr. Mukherjee, School of

Natural Products, JU on the skill to write a good manuscript for

publication in impact journals. It was followed by nearly two hour

long discussion among more than thirty participants on differentaspects of pharmacy education. Five nonmember participants

applied for membership on that very day.

GNIPST is now approved by AICTE and affiliated to WBUT for

conducting the two years post graduate course (M.Pharm) in

P H A R M A C O L O G Y .The approved number of seat is 18.The number of seats in B.Pharm. has been increased from 60 to

120.

AICTE has sanctioned a release of grant under Research

Promotion Scheme (RPS) during the financial year 2012-13to

GNIPST as per the details below:

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a. Beneficiary Institution:Guru Nanak Institution of Pharmaceutical

Science & Technology.

b.Principal Investigator:Dr. LopamudraDutta.

c. Grant-in-aid sanctioned:Rs. 16,25000/- onlyd.Approved duration: 3 years

e. Title of the project:Screening and identification of potential

medicinal plant of Purulia & Bankura districts of West Bengal

with respect to diseases such as diabetes, rheumatism, Jaundice,

hypertension and developing biotechnological tools for enhancing

bioactive molecules in these plants.

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Gnipst Bulletin 31.1

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