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    1118-1177-4796-9849-7562-5062mail

    GNIPST BULLETIN 2012

    21st

    December 2012 Volume No.: 21 Issue No.: 0

    Contents Message from GNIPS

    Letter to the Editor News Update

    Disease Outbreak Ne

    Health Awareness

    Forth Coming Events

    Drugs Update

    Campus News

    Students Section

    Editors Note

    Archive

    Vision

    TO GROW AS A CENTRE OF EXCELLENCE IN THE FIELD O

    PHARMACEUTICAL AND BIOLOGICAL SCIENCE

    EDITOR: Debabrata Ghosh DastidarGURU NANAK INSTITUTE OF PHARMACEUTICAL SCIENCE AND

    TECHNOLOGY

    GNIPST Photo Gallery

    For your comments/contribution

    ack-Issues,

    mailto:[email protected]

    https://picasaweb.google.com/111714720327580099858/FreshersWelcome20122012mailto:[email protected]:[email protected]:[email protected]://picasaweb.google.com/111714720327580099858/FreshersWelcome20122012
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    MESSAGE FROM GNIPST

    All the members of GNIPST are proud to publish the 21st

    Volume

    of GNIPST BULLETIN. This bulletin has successfully

    completed its twenty months journey. We hope it has kept the

    readers updated of recent activities in pharmaceutical & biological

    sciences and also introduced them with the different activities of

    our esteemed institution. We are thankful to all of you for your

    great cooperation & support and are looking forward to the same in

    future.

    LETTER TO THE EDITOR.

    NEWS UPDATE

    New Targets for Drugs to Defeat Aggressive

    Brain Tumor(14DECEMBER 2012

    )Researchers have identified over 125 genetic components in a

    chemotherapy-resistant, brain tumor-derived cell line, which

    could offer new hope for drug treatment to destroy the cancer

    cells. The potential drug targets were identified after testing more

    than 5,000 genes derived from glioblastoma multiforme. Antidepressant Could Do Double Duty as

    Diabetes Drug, Study Shows (14 DECEMBER 2012)

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    Researchers have discovered that the commonly used anti-

    depressant drug paroxetine could also become a therapy for the

    vascular complications of diabetes.

    Dogs Can Accurately Sniff out 'Superbug'

    Infections(13 DECEMBER 2012)

    Dogs can sniff out Clostridium difficile (the infective agent that is

    responsible for many of the dreaded "hospital acquired infections")

    in stool samples and even in the air surrounding patients inhospital with a very high degree of accuracy, a new study finds.

    Drug Used to Treat HIV Might Defuse Deadly

    Staph Infections?(14 DECEMBER 2012)

    A new study suggests that an existing HIV drug called

    could be a potential therapy for Staphylococcus aureus, a notorious

    and deadly pathogen linked to hundreds of thousands of

    hospitalizations each year.

    Ordinary Heart Cells Become 'Biological

    Pacemakers' With Injection of Single Gene?

    (16 DECEMBER 2012)

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    Researchers have reprogrammed ordinary heart cells to become

    exact replicas of highly specialized pacemaker cells by injecting a

    single gene -- a major step forward in the decade-long search for a

    biological therapy to correct erratic and failing heartbeats.

    Scientists Developing Quick Way to ID People

    Exposed to Ionizing Radiation(17 DECEMBER 2012)

    A new study could lead to a blood test that detects if a person has

    been exposed to radiation, measures their dose, and separates

    people suffering from inflammation injuries -- all in a matter of

    hours. They identified eight DNA-repair genes in human blood

    whose expression responses change more than twofold soon after

    blood is exposed to radiation.

    New Technology May Enable Earlier Cancer

    Diagnosis: Nanoparticles Amplify Tumor Signals,

    Making Them Much Easier to Detect in Urine

    (17 DECEMBER 2012)

    Finding ways to diagnose cancer earlier could greatly improve the

    chances of survival for many patients. One way to do this is to look

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    for specific proteins secreted by cancer cells, which circulate in the

    bloodstream. However, the quantity of these biomarkers is so low

    that detecting them has proven difficult. A new technology may

    help to make biomarker detection much easier. Researchers have

    developed nanoparticles that can home to a tumor and interact

    with cancer proteins to produce thousands of biomarkers, which

    can then be easily detected in the patient's urine.

    Pocket Test Measures Fifty Things in a Drop of

    Blood (19 DECEMBER 2012)

    A new device about the size of a business card could allow health

    care providers to test for insulin and other blood proteins,

    cholesterol, and even signs of viral or bacterial infection all at the

    same time - with one drop of blood.

    Super-Fine Sound Beam Could One Day Be an

    Invisible Scalpel(19 DECEMBER 2012)

    A carbon-nanotube-coated lens that converts light to sound can

    focus high-pressure sound waves to finer points than ever before.

    The engineering researchers who developed the new therapeutic

    ultrasound approach say it could lead to an invisible knife for

    noninvasive surgery.

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    http://www.sciencedaily.com/releases/2012/12/121217140738.htm?utm_source=feedburner&utm_medium=email&utm_campaign=Feed%3A+sciencedaily%2Fhealth_medicine+%28ScienceDaily%3A+Health+%26+Medicine+News%29http://www.sciencedaily.com/releases/2012/12/121219152621.htm?utm_source=feedburner&utm_medium=email&utm_campaign=Feed%3A+sciencedaily%2Fhealth_medicine+%28ScienceDaily%3A+Health+%26+Medicine+News%29http://www.sciencedaily.com/releases/2012/12/121219173955.htm?utm_source=feedburner&utm_medium=email&utm_campaign=Feed%3A+sciencedaily%2Fhealth_medicine+%28ScienceDaily%3A+Health+%26+Medicine+News%29http://www.sciencedaily.com/releases/2012/12/121219173955.htm?utm_source=feedburner&utm_medium=email&utm_campaign=Feed%3A+sciencedaily%2Fhealth_medicine+%28ScienceDaily%3A+Health+%26+Medicine+News%29http://www.sciencedaily.com/releases/2012/12/121219173955.htm?utm_source=feedburner&utm_medium=email&utm_campaign=Feed%3A+sciencedaily%2Fhealth_medicine+%28ScienceDaily%3A+Health+%26+Medicine+News%29http://www.sciencedaily.com/releases/2012/12/121219152621.htm?utm_source=feedburner&utm_medium=email&utm_campaign=Feed%3A+sciencedaily%2Fhealth_medicine+%28ScienceDaily%3A+Health+%26+Medicine+News%29http://www.sciencedaily.com/releases/2012/12/121217140738.htm?utm_source=feedburner&utm_medium=email&utm_campaign=Feed%3A+sciencedaily%2Fhealth_medicine+%28ScienceDaily%3A+Health+%26+Medicine+News%29
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    HEALTH AWARENESS

    Oral health

    Oral health is essential to general health and quality of life. It is a

    state of being free from mouth and facial pain, oral and throat

    cancer, oral infection and sores, periodontal (gum) disease, tooth

    decay, tooth loss, and other diseases and disorders that limit an

    individuals capacity in biting, chewing, smiling, speaking, and

    psychosocial wellbeing.

    The most common oral diseases are dental cavities, periodontal

    (gum) disease, oral cancer, oral infectious diseases, trauma from

    injuries, and hereditary lesions.

    Dental cavities

    Worldwide, 6090% of school children and nearly 100% of adults

    have dental cavities, often leading to pain and discomfort.

    Periodontal disease

    Severe periodontal (gum) disease, which may result in tooth loss,

    is found in 1520% of middle-aged (35-44 years) adults.

    Tooth loss

    Dental cavities and periodontal disease are major causes of tooth

    loss. Complete loss of natural teeth is widespread and particularly

    affects older people. Globally, about 30% of people aged 6574

    have no natural teeth.

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    Oral cancer

    The incidence of oral cancer ranges from one to 10 cases per 100

    000 people in most countries. The prevalence of oral cancer is

    relatively higher in men, in older people, and among people of loweducation and low income. Tobacco and alcohol are major causal

    factors.

    Fungal, bacterial or viral infections in HIV

    Almost half (4050%) of people who are HIV-positive have oral

    fungal, bacterial or viral infections. These often occur early in the

    course of HIV infection.

    Oro-dental trauma

    Across the world, 16-40% of children in the age range 6 to12 years

    old are affected by dental trauma due to unsafe playgrounds,

    unsafe schools, road accidents, or violence.

    Noma

    Noma is a gangrenous lesion that affects young children living in

    extreme poverty primarily in Africa and Asia. Lesions are severe

    gingival disease followed by necrosis (premature death of cells in

    living tissue) of lips and chin. Many children affected by noma

    suffer from other infections such as measles and HIV. Without any

    treatment, about 90% of these children die.

    Cleft lip and palate

    Birth defects such as cleft lip and palate occur in about one per

    500700 of all births. This rate varies substantially across different

    ethnic groups and geographical areas.

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    Common causes

    Risk factors for oral diseases include an unhealthy diet, tobacco

    use and harmful alcohol use. These are also risk factors for the four

    leading chronic diseases cardiovascular diseases, cancer, chronicrespiratory diseases and diabetes and oral diseases are often

    linked to chronic disease. Poor oral hygiene is also a risk factor for

    oral disease.

    The prevalence of oral disease varies by geographical region, and

    availability and accessibility of oral health services. Social

    determinants in oral health are also very strong. The prevalence oforal diseases is increasing in low- and middle-income countries,

    and in all countries, the oral disease burden is significantly higher

    among poor and disadvantaged population groups.

    Prevention and treatment

    The burden of oral diseases and other chronic diseases can be

    decreased simultaneously by addressing common risk factors.These include:

    o decreasing sugar intake and maintaining a well-balanced

    nutritional intake to prevent tooth decay and premature

    tooth loss;

    o consuming fruit and vegetables that can protect against oral

    cancer;

    o stopping tobacco use and decreasing alcohol consumption toreduce the risk of oral cancers, periodontal disease and tooth

    loss;

    o ensuring proper oral hygiene;

    o using protective sports and motor vehicle equipment to

    reduce the risk of facial injuries; and

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    o safe physical environments.

    Dental cavities can be prevented by maintaining a constant low

    level of fluoride in the oral cavity. Fluoride can be obtained from

    fluoridated drinking water, salt, milk and toothpaste, as well as

    from professionally-applied fluoride or mouth rinse. Long-term

    exposure to an optimal level of fluoride results in fewer dental

    cavities in both children and adults.

    Most oral diseases and conditions require professional dental care,

    however, due to limited availability or inaccessibility, the use of

    oral health services is markedly low among older people, people

    living in rural areas, and people with low income and education.

    Oral health care coverage is low in low- and middle- income

    countries.

    Traditional curative dental care is a significant economic burden

    for many high-income countries, where 510% of public health

    expenditure relates to oral health. In low- and middle-income

    countries, public oral health programmes are rare. The high cost of

    dental treatment can be avoided by effective prevention and health

    promotion measures.

    DISEASE OUTBREAK NEWS

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    FORTHCOMING EVENTS

    DRUGS UPDATES

    FDA permits marketing of device to seal lung

    punctures (19 DECEMBER 2012)

    The U.S. FDA allowed marketing of the

    , a device that seals punctures left by biopsies

    performed to confirm a diagnosis of suspected lung conditions.

    CAMPUS NEWS

    There are needs of pharmacists (D.Pharm./B.Pharm.) in

    Bhagirathi Neotia Women & Child Health Care Centre.Interested persons are required to contact Registrar Sir (Prof.

    Dipankar Chakraborty) immediately.

    STUDENTS SECTION

    WHO CAN ANSWER FIRST???() MAKRUK is the THAI version of which

    board game?

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    http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm332714.htm
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    () Which was the first Indian armed force toinduct women into combat role?

    A) HMG-CoA B)Simvastatin

    [email protected]

    EDITORS NOTE

    I am very happy to publish the 4th

    issue of 20th

    Volume of GNIPST

    BULLETIN. It is my great pleasure to introduce you to the newly

    launched facebook account GNIPST bulletin. You are cordially

    invited to add this account to your friend list. The current issues will

    also be directly available on facebook.

    I would like to convey my thanks to all the GNIPST members and

    the readers for their valuable comments, encouragement& supports.

    Special thanks to Dr. Prerona Saha for her advice; Mr. Soumya

    Bhattacharya, for his contribution in students section.

    It would be my great pleasure to receive the contributions,

    suggestions & feedback from your desk for further upliftment of this

    deliberation GNIPST BULLETIN.

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    mailto:[email protected]:[email protected]:[email protected]
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    ARCHIVE

    The general body meeting of APTI, Bengal Branch has been

    conducted at GNIPST on 15

    th

    June, 2012. The programme startedwith a nice presentation by Dr. Pulok Kr. Mukherjee, School of

    Natural Products, JU on the skill to write a good manuscript for

    publication in impact journals. It was followed by nearly two hour

    long discussion among more than thirty participants on different

    aspects of pharmacy education. Five nonmember participants

    applied for membership on that very day.

    GNIPST is now approved by AICTE and affiliated to WBUT for

    conducting the two years post graduate course (M.Pharm) in

    The approved number of seat is 18.

    The number of seats in B.Pharm. has been increased from 60 to

    120.

    2nd World Congress on Ga-68 (Generators and Novel Radiopharmaceuticals),

    Molecular Imaging (PET/CT), Targeted Radionuclide Therapy, and

    Dosimetry (SWC-2013) : On the Way to Personalized Medicine

    Dates 28 Feb 2013

    02 Mar 2013Location: Chandigarh, India.

    5-Days Hands-on Workshop on Molecular Biotechnology and Bioinformatics.

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    http://www.2ndworldcongress-ga-68.de/http://www.2ndworldcongress-ga-68.de/http://www.2ndworldcongress-ga-68.de/
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    7thto 11th January 2013, Pune, Maharashtra, India.

    IAMLE- 2013 4th International Conference on Medical Negligence and

    litigation in Medical Practice, and 4th International Conference on Recent

    Advances in Forensic Sciences, Forensic Medicine & Toxicology.

    Date: 25 Jan 2013 27 Jan 2013, Location: Kovalam, Thiruvanthapuram,

    India.

    will be held

    from , at Chennai. The four-day event

    will be organized by the Association of Pharmacy Teachers of India

    (APTI).

    45th Annual Conference of Indian pharmacological Society &

    International Conference on

    will be organized at on

    Jan 05-07, 2013.

    For further detail, visit:http://www.ipsnagpur2012.org/InternalPage.aspx

    AICTE has sanctioned a release of grant under Research

    Promotion Scheme (RPS) during the financial year 2012-

    13 to GNIPST as per the details below:

    a. Beneficiary Institution: Guru Nanak Institution of

    Pharmaceutical Science & Technology.

    b. Principal Investigator: Dr. Lopamudra Dutta.

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    http://www.icsccb.org/workshops/http://www.icsccb.org/workshops/http://www.iamleconf.in/homehttp://www.iamleconf.in/homehttp://www.ipsnagpur2012.org/InternalPage.aspxhttp://www.ipsnagpur2012.org/InternalPage.aspxhttp://www.ipsnagpur2012.org/InternalPage.aspxhttp://www.ipsnagpur2012.org/InternalPage.aspxhttp://www.iamleconf.in/homehttp://www.icsccb.org/workshops/
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    c. Grant-in-aid sanctioned: Rs. 16,25000/- only

    d.Approved duration: 3 years

    e. Title of the project: Screening and identification of

    potential medicinal plant ofPurulia & Bankura districts of West

    Bengal with respect to diseases such as diabetes, rheumatism,

    Jaundice, hypertension and developing biotechnological tools for

    enhancing bioactive molecules in these plant.

    Special classes on Communication Skills, G.D. and

    Interview will commence from 3rd week of January 2013for the students of this Institute. Interested students are

    required to contact the undersigned for enrolment either

    personally or by e-mail.

    Dr. Lopamudra Datta

    E-mail: [email protected]

    [email protected]

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