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GNIPST BULLETIN 2012
21st
December 2012 Volume No.: 21 Issue No.: 0
Contents Message from GNIPS
Letter to the Editor News Update
Disease Outbreak Ne
Health Awareness
Forth Coming Events
Drugs Update
Campus News
Students Section
Editors Note
Archive
Vision
TO GROW AS A CENTRE OF EXCELLENCE IN THE FIELD O
PHARMACEUTICAL AND BIOLOGICAL SCIENCE
EDITOR: Debabrata Ghosh DastidarGURU NANAK INSTITUTE OF PHARMACEUTICAL SCIENCE AND
TECHNOLOGY
GNIPST Photo Gallery
For your comments/contribution
ack-Issues,
mailto:[email protected]
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MESSAGE FROM GNIPST
All the members of GNIPST are proud to publish the 21st
Volume
of GNIPST BULLETIN. This bulletin has successfully
completed its twenty months journey. We hope it has kept the
readers updated of recent activities in pharmaceutical & biological
sciences and also introduced them with the different activities of
our esteemed institution. We are thankful to all of you for your
great cooperation & support and are looking forward to the same in
future.
LETTER TO THE EDITOR.
NEWS UPDATE
New Targets for Drugs to Defeat Aggressive
Brain Tumor(14DECEMBER 2012
)Researchers have identified over 125 genetic components in a
chemotherapy-resistant, brain tumor-derived cell line, which
could offer new hope for drug treatment to destroy the cancer
cells. The potential drug targets were identified after testing more
than 5,000 genes derived from glioblastoma multiforme. Antidepressant Could Do Double Duty as
Diabetes Drug, Study Shows (14 DECEMBER 2012)
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Researchers have discovered that the commonly used anti-
depressant drug paroxetine could also become a therapy for the
vascular complications of diabetes.
Dogs Can Accurately Sniff out 'Superbug'
Infections(13 DECEMBER 2012)
Dogs can sniff out Clostridium difficile (the infective agent that is
responsible for many of the dreaded "hospital acquired infections")
in stool samples and even in the air surrounding patients inhospital with a very high degree of accuracy, a new study finds.
Drug Used to Treat HIV Might Defuse Deadly
Staph Infections?(14 DECEMBER 2012)
A new study suggests that an existing HIV drug called
could be a potential therapy for Staphylococcus aureus, a notorious
and deadly pathogen linked to hundreds of thousands of
hospitalizations each year.
Ordinary Heart Cells Become 'Biological
Pacemakers' With Injection of Single Gene?
(16 DECEMBER 2012)
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Researchers have reprogrammed ordinary heart cells to become
exact replicas of highly specialized pacemaker cells by injecting a
single gene -- a major step forward in the decade-long search for a
biological therapy to correct erratic and failing heartbeats.
Scientists Developing Quick Way to ID People
Exposed to Ionizing Radiation(17 DECEMBER 2012)
A new study could lead to a blood test that detects if a person has
been exposed to radiation, measures their dose, and separates
people suffering from inflammation injuries -- all in a matter of
hours. They identified eight DNA-repair genes in human blood
whose expression responses change more than twofold soon after
blood is exposed to radiation.
New Technology May Enable Earlier Cancer
Diagnosis: Nanoparticles Amplify Tumor Signals,
Making Them Much Easier to Detect in Urine
(17 DECEMBER 2012)
Finding ways to diagnose cancer earlier could greatly improve the
chances of survival for many patients. One way to do this is to look
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for specific proteins secreted by cancer cells, which circulate in the
bloodstream. However, the quantity of these biomarkers is so low
that detecting them has proven difficult. A new technology may
help to make biomarker detection much easier. Researchers have
developed nanoparticles that can home to a tumor and interact
with cancer proteins to produce thousands of biomarkers, which
can then be easily detected in the patient's urine.
Pocket Test Measures Fifty Things in a Drop of
Blood (19 DECEMBER 2012)
A new device about the size of a business card could allow health
care providers to test for insulin and other blood proteins,
cholesterol, and even signs of viral or bacterial infection all at the
same time - with one drop of blood.
Super-Fine Sound Beam Could One Day Be an
Invisible Scalpel(19 DECEMBER 2012)
A carbon-nanotube-coated lens that converts light to sound can
focus high-pressure sound waves to finer points than ever before.
The engineering researchers who developed the new therapeutic
ultrasound approach say it could lead to an invisible knife for
noninvasive surgery.
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HEALTH AWARENESS
Oral health
Oral health is essential to general health and quality of life. It is a
state of being free from mouth and facial pain, oral and throat
cancer, oral infection and sores, periodontal (gum) disease, tooth
decay, tooth loss, and other diseases and disorders that limit an
individuals capacity in biting, chewing, smiling, speaking, and
psychosocial wellbeing.
The most common oral diseases are dental cavities, periodontal
(gum) disease, oral cancer, oral infectious diseases, trauma from
injuries, and hereditary lesions.
Dental cavities
Worldwide, 6090% of school children and nearly 100% of adults
have dental cavities, often leading to pain and discomfort.
Periodontal disease
Severe periodontal (gum) disease, which may result in tooth loss,
is found in 1520% of middle-aged (35-44 years) adults.
Tooth loss
Dental cavities and periodontal disease are major causes of tooth
loss. Complete loss of natural teeth is widespread and particularly
affects older people. Globally, about 30% of people aged 6574
have no natural teeth.
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Oral cancer
The incidence of oral cancer ranges from one to 10 cases per 100
000 people in most countries. The prevalence of oral cancer is
relatively higher in men, in older people, and among people of loweducation and low income. Tobacco and alcohol are major causal
factors.
Fungal, bacterial or viral infections in HIV
Almost half (4050%) of people who are HIV-positive have oral
fungal, bacterial or viral infections. These often occur early in the
course of HIV infection.
Oro-dental trauma
Across the world, 16-40% of children in the age range 6 to12 years
old are affected by dental trauma due to unsafe playgrounds,
unsafe schools, road accidents, or violence.
Noma
Noma is a gangrenous lesion that affects young children living in
extreme poverty primarily in Africa and Asia. Lesions are severe
gingival disease followed by necrosis (premature death of cells in
living tissue) of lips and chin. Many children affected by noma
suffer from other infections such as measles and HIV. Without any
treatment, about 90% of these children die.
Cleft lip and palate
Birth defects such as cleft lip and palate occur in about one per
500700 of all births. This rate varies substantially across different
ethnic groups and geographical areas.
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Common causes
Risk factors for oral diseases include an unhealthy diet, tobacco
use and harmful alcohol use. These are also risk factors for the four
leading chronic diseases cardiovascular diseases, cancer, chronicrespiratory diseases and diabetes and oral diseases are often
linked to chronic disease. Poor oral hygiene is also a risk factor for
oral disease.
The prevalence of oral disease varies by geographical region, and
availability and accessibility of oral health services. Social
determinants in oral health are also very strong. The prevalence oforal diseases is increasing in low- and middle-income countries,
and in all countries, the oral disease burden is significantly higher
among poor and disadvantaged population groups.
Prevention and treatment
The burden of oral diseases and other chronic diseases can be
decreased simultaneously by addressing common risk factors.These include:
o decreasing sugar intake and maintaining a well-balanced
nutritional intake to prevent tooth decay and premature
tooth loss;
o consuming fruit and vegetables that can protect against oral
cancer;
o stopping tobacco use and decreasing alcohol consumption toreduce the risk of oral cancers, periodontal disease and tooth
loss;
o ensuring proper oral hygiene;
o using protective sports and motor vehicle equipment to
reduce the risk of facial injuries; and
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o safe physical environments.
Dental cavities can be prevented by maintaining a constant low
level of fluoride in the oral cavity. Fluoride can be obtained from
fluoridated drinking water, salt, milk and toothpaste, as well as
from professionally-applied fluoride or mouth rinse. Long-term
exposure to an optimal level of fluoride results in fewer dental
cavities in both children and adults.
Most oral diseases and conditions require professional dental care,
however, due to limited availability or inaccessibility, the use of
oral health services is markedly low among older people, people
living in rural areas, and people with low income and education.
Oral health care coverage is low in low- and middle- income
countries.
Traditional curative dental care is a significant economic burden
for many high-income countries, where 510% of public health
expenditure relates to oral health. In low- and middle-income
countries, public oral health programmes are rare. The high cost of
dental treatment can be avoided by effective prevention and health
promotion measures.
DISEASE OUTBREAK NEWS
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FORTHCOMING EVENTS
DRUGS UPDATES
FDA permits marketing of device to seal lung
punctures (19 DECEMBER 2012)
The U.S. FDA allowed marketing of the
, a device that seals punctures left by biopsies
performed to confirm a diagnosis of suspected lung conditions.
CAMPUS NEWS
There are needs of pharmacists (D.Pharm./B.Pharm.) in
Bhagirathi Neotia Women & Child Health Care Centre.Interested persons are required to contact Registrar Sir (Prof.
Dipankar Chakraborty) immediately.
STUDENTS SECTION
WHO CAN ANSWER FIRST???() MAKRUK is the THAI version of which
board game?
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() Which was the first Indian armed force toinduct women into combat role?
A) HMG-CoA B)Simvastatin
EDITORS NOTE
I am very happy to publish the 4th
issue of 20th
Volume of GNIPST
BULLETIN. It is my great pleasure to introduce you to the newly
launched facebook account GNIPST bulletin. You are cordially
invited to add this account to your friend list. The current issues will
also be directly available on facebook.
I would like to convey my thanks to all the GNIPST members and
the readers for their valuable comments, encouragement& supports.
Special thanks to Dr. Prerona Saha for her advice; Mr. Soumya
Bhattacharya, for his contribution in students section.
It would be my great pleasure to receive the contributions,
suggestions & feedback from your desk for further upliftment of this
deliberation GNIPST BULLETIN.
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ARCHIVE
The general body meeting of APTI, Bengal Branch has been
conducted at GNIPST on 15
th
June, 2012. The programme startedwith a nice presentation by Dr. Pulok Kr. Mukherjee, School of
Natural Products, JU on the skill to write a good manuscript for
publication in impact journals. It was followed by nearly two hour
long discussion among more than thirty participants on different
aspects of pharmacy education. Five nonmember participants
applied for membership on that very day.
GNIPST is now approved by AICTE and affiliated to WBUT for
conducting the two years post graduate course (M.Pharm) in
The approved number of seat is 18.
The number of seats in B.Pharm. has been increased from 60 to
120.
2nd World Congress on Ga-68 (Generators and Novel Radiopharmaceuticals),
Molecular Imaging (PET/CT), Targeted Radionuclide Therapy, and
Dosimetry (SWC-2013) : On the Way to Personalized Medicine
Dates 28 Feb 2013
02 Mar 2013Location: Chandigarh, India.
5-Days Hands-on Workshop on Molecular Biotechnology and Bioinformatics.
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7thto 11th January 2013, Pune, Maharashtra, India.
IAMLE- 2013 4th International Conference on Medical Negligence and
litigation in Medical Practice, and 4th International Conference on Recent
Advances in Forensic Sciences, Forensic Medicine & Toxicology.
Date: 25 Jan 2013 27 Jan 2013, Location: Kovalam, Thiruvanthapuram,
India.
will be held
from , at Chennai. The four-day event
will be organized by the Association of Pharmacy Teachers of India
(APTI).
45th Annual Conference of Indian pharmacological Society &
International Conference on
will be organized at on
Jan 05-07, 2013.
For further detail, visit:http://www.ipsnagpur2012.org/InternalPage.aspx
AICTE has sanctioned a release of grant under Research
Promotion Scheme (RPS) during the financial year 2012-
13 to GNIPST as per the details below:
a. Beneficiary Institution: Guru Nanak Institution of
Pharmaceutical Science & Technology.
b. Principal Investigator: Dr. Lopamudra Dutta.
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c. Grant-in-aid sanctioned: Rs. 16,25000/- only
d.Approved duration: 3 years
e. Title of the project: Screening and identification of
potential medicinal plant ofPurulia & Bankura districts of West
Bengal with respect to diseases such as diabetes, rheumatism,
Jaundice, hypertension and developing biotechnological tools for
enhancing bioactive molecules in these plant.
Special classes on Communication Skills, G.D. and
Interview will commence from 3rd week of January 2013for the students of this Institute. Interested students are
required to contact the undersigned for enrolment either
personally or by e-mail.
Dr. Lopamudra Datta
E-mail: [email protected]
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