Growing the health and wealth

of the nation through research

Dr Matthew Hallsworth, Head of External Relations at the NIHR Office

for Clinical Research Infrastructure (NOCRI)

Matt Cooper, Business Development Manager and Marketing Director at NIHR Clinical Research Network

Professor Ian Bruce, Director of the NIHR Manchester

Musculoskeletal Biomedical Research Unit and Deputy Director of the

NIHR / Wellcome Trust Manchester Clinical Research Facility Alastair Smith, Director of Business Development, Myriad RBM, Inc.

Dr Matthew Hallsworth

Head of External Relations at the NIHR Office for Clinical Research Infrastructure (NOCRI)

Growing the health and wealth of the nation through research

The National Institute for Health Research is funded through the Department of Health to improve the health and

wealth of the nation through research. It is a large, multi-faceted and nationally distributed organisation.

The NIHR manages its health research activities through four main work strands:

RESEARCH: funding research to generate innovative new healthcare solutions

INFRASTRUCTURE: providing the facilities and the people to conduct first-class research in the NHS

FACULTY: supporting the individuals leading and carrying out research

SYSTEMS: promoting faster, easier clinical research through unified, streamlined and simple systems for managing

ethical research and its outputs.

Investment into the NIHR has driven the transformation of health research within the NHS.

About the NIHR

Growing the health and wealth of the nation through research

NIHR Contribution to Growth

THE NIHR’S KEY CONTRIBUTIONS TO GROWTH INCLUDE:

Supporting collaborations and contract research with the life sciences industry

Creating the research environment that supports the nation’s international

competitiveness

Attracting, developing and retaining a highly skilled health research workforce

Providing the clinical evidence to help the NHS and public sector to make efficient

use of resources

Providing the research evidence that contributes to establishing a healthier workforce

and wider population

Growing the health and wealth of the nation through research

Collaborative working is central to the NIHR’s aim to advance treatments, new diagnostics and medical technologies for

patients and to drive growth.

This contributes to growth through:

attracting investment into the UK

supporting companies based within in the UK

supporting the establishment and growth of UK SME’s

supporting academic researchers to work in partnership with industry.

NIHR Office for Clinical Research Infrastructure (NOCRI)

NOCRI provides the life sciences industry with direct and simple access to :

a wide range of translational research experts and facilities

expert NIHR investigators who can help companies understand the potential of their developmental drugs, devices

and diagnostics

Collaborating with Industry

Growing the health and wealth of the nation through research

The NIHR translational research infrastructure gives industry access to word-class

facilities and the opportunity to work in collaboration with expert investigators.

£120 MILLION

ANNUAL

INVESTMENT FROM

INDUSTRY

The NIHR translational

research infrastructure

has quadrupled its

annual investment by

industry over the last

five years from £33

million per year in

2009/10 to £120 million

per year in 2013/14

585 STRATEGIC

PARTNERSHIPS

WITH INDUSTRY

The NIHR

translational research

infrastructure had

347 existing strategic

partnerships and

developed 238 new

strategic partnerships

with industry during

2013/14

£33.9 MILLION THROUGH

THE EXPLOITATION OF IP

The NIHR translational research

infrastructure generated £33.9m

from exploiting intellectual

property, including the launch of

six spin out companies in

2013/14.

500 PROJECTS with UK SME’s

In 2013/14 the NIHR translational research infrastructure worked

with SME’s during 2013/14 to support more than 500 research

projects

500% INCREASE

The number of industry

studies supported by the

NIHR translational research

infrastructure has increased

by over five-fold from 514 to

2640 studies in 2013/14

Focus on:

Translational Research Infrastructure

GROWTH

THROUGH HEALTH

RESEARCH

The NIHR as an engine for growth

Matt Cooper

Business Development Manager and Marketing Director at NIHR Clinical Research Network

Growing the health and wealth of the nation through research

Myth busting

Growing the health and wealth of the nation through research

The data

No studies up

No recruits up

Delivery up

Set up reduced

Growing the health and wealth of the nation through research

Service offer

FEASIBILITY Manage and deliver:

• Early Feedback

• Site Intelligence

• Site Identification

COMMERCIAL COSTING

TEMPLATES • Support use

• Manage templates

• Trust, Primary Care &

Device versions

NIHR COORDINATED SYSTEM FOR GAINING NHS PERMISSION

• Support use

MODEL AGREEMENTS

• Support use

STUDY MANAGEMENT • Collect & collate

data

• Performance

manage study

Feasibility Set-up Delivery

Professor Ian Bruce

Director of the NIHR Manchester Musculoskeletal Biomedical Research

Unit and Deputy Director of the NIHR / Wellcome Trust Manchester Clinical Research Facility

Growing the health and wealth of the nation through research

How BRUs/BRCs are leveraging income nationally

NIHR Early Phase / EM Infrastructure

Growing the health and wealth of the nation through research

Leveraging income: Co-ordination and collaboration

Early phase EM studies

• New molecules

• New devices

• Unmet needs

Stratified Medicine Consortia

• New devices

• Unmet needs

TRPs: collaborative early phase

clinical development

• Pre-clinical to clinical inc. FIH,

biomarker, MoA studies

• Well characterised cohorts

• Operational support from

NOCRI

– >30 UK institutions: one

operational agreement**

Alastair Smith

Director of Business Development, Myriad RBM, Inc.

Growing the health and wealth of the nation through research

NIHR assisting Myriad RBM

Diagnostic

Evidence

Co-operative