Date post: | 22-Jan-2018 |
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www.guidetopharmacology.org
GtoPdb and GtoImmuPdb in the context of
other informatics resources
Chris Southan
NC-IUPHAR and BPS Focused Meeting on the Guide to IMMUNOPHARMACOLOGY, 9-10
April 2016, Edinburgh
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http://www.slideshare.net/cdsouthan/gtopdb-and-gtoimmpdb-in-context
GtoImmuPdb has no direct overlap
• ImmPort focused on the collation of data sets
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ImmunoDB
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• also primarily for data input
Immune Epitope Database 2.0
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Collaborative
opportunities
immgen.org
5
• Currently mouse but will expand to human
The GtoPdb ecosystem is crowded
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http://www.guidetopharmacology.org/helpPage.jsp#databaseLinks
Direct overlaps (I)
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Direct overlaps (II)
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Overlapping content by protein targets
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Overlapping content by chemistry
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• 1259 GtoPdb CIDs are not in the other three
• We all concur on 1036
Integrated bioactivity databases: also getting crowded
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http://cdsouthan.blogspot.co.uk/2015/11/integrated-bioactivity-databases.html
Integrated databases: specificity issues
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Important sub-ecosystem
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Subset overlaps (I)
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Subset overlaps (II)
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Discussion points
• Maximising GtoImmuPdb expansion
• Sustaining GtoPdb expansion
• Adding/enhancing unique content/quality/divergence
• Advertising/highlighting unique value
• Collaborative opportunities
• Dealing with errors in other resources
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