Gut And Psychology Syndrome Gut And Physiology Syndrome

The 1st WAPF UK conferenceDr Natasha Campbell-McBride MD

All diseases begin in the gut!Hippocrates, 460-370 BC

Gut And Psychology / Gut And Physiology Syndrome

GAP Syndrome establishes a connection

between the state of the gut and the health

of the rest of the body

Protection from Invaders

Health and Integrity of the Gut

Appropriate Digestion and Absorption

Vitamin Production

Detoxification

Immune System Modulation

Roles of Gut Flora

What can damage gut flora

• Antibiotics

• Steroids, The Pill

• Other Drugs

• Stress

• Poor Diet

• Infections

• Disease

• Bottle Feeding

• Old Age

• Pollution

• Radiation

• Alcohol

• Toxic Chemicals

• Dental Work

A Typical Scenario• Mother with gut dysbiosis

• The baby does not develop normal gut flora

• Immune system compromised

• Ear infections, antibiotics

• Chest infections, antibiotics

• Further damage to gut flora & immune system

• Vaccinations

• Usual weaning diet

• Gut dysbiosis leads to damaged gut wall

• Toxins, microbes, undigested foods enter the body

•Autoimmunity joins in

DAMAGED GUT WALL

• Lack of protection by beneficial gut flora

• Attack by pathogenic microbes & toxins

• Enterocytes degenerate, tight junctions open

• Foods absorb partially digested leading to food allergies & intolerances

• Damaged gut lets toxins & microbes through into the blood steam

• General toxicity in the body

• Immune system reacts adding autoimmunity

Cleaning the flow from the gut

Water soluble nutrients & toxins

• Stage 1: through the gut wall into the blood steam

• Stage 2: liver• Stage 3: lungs

Fat soluble nutrients & toxins

• Stage 1: through the gut wall into lymph

• Stage 2: lungs

Liver• Greatly increased toxic flow from the gut

• Blocked detox pathways

• Toxins by-pass filtering & go into the blood stream

• From the environment: heavy metals, phenols, petro-chemicals, glue adhesives, agricultural chemicals, personal care & cleaning products, plasticisers, etc, etc

• By-products of body’s own metabolism

• All liver functions suffer

Lungs•Toxins, undigested foods, microbes eliminate through phagocytes & “mucociliary escalator”

•Toxic gases escape

•Damage to bronchi

•Bronchospasm (wheeze) - a protective mechanism for healing bronchi

•Anti-asthma drugs stop this mechanism leading to long-term lung damage

D Freed, J Mansfield. Asthma: What we do and why we do it. JNutr&EnvirMed, June 2008,17(2):97-110

Gut and Physiology Syndrome: Asthma

• Used to be a benign condition (no asthma mortality) until anti-asthma drugs invented in 1950-60s

• Now a deadly disease

• Anti-asthma drugs do not allow the lungs to eliminate toxins and heal the damage

• Toxins go elsewhere in the body, causing damage

• Fatal food allergies are associated with “well-controlled” asthma

Committee on Toxicity of Chemicals in Food. CTCFCPE; 2007, p.25, Crown Copyright

Gut and Physiology Syndrome Elimination of toxins & undigested food

• through lungs: asthma, other chronic lung conditions

• through skin: eczema, other skin problems

• through urine: chronic cystitis, bed wetting, thrush

• through mucous membranes: sinusitis, post-nasal drip, rhinitis, gingivitis, vaginitis, diarrhoea/constipation, etc – all chronic

Gut and Physiology SyndromeAutoimmunity

• Caused by absorption of protein and peptide complexes through damaged gut wall

• Immune system produces antibodies, which then attack body’s own tissues

• In type 1 diabetes pancreatic cells are attacked

• In celiac disease small intestine is attacked

• In MS, autism & other neurological problems nervous system is attacked

• Always more than one tissue is attacked

Gut And Physiology Syndrome• Autoimmunity: multiple sclerosis,

rheumatoid arthritis, diabetes type one, celiac disease, osteoarthritis, lupus, etc

• Arthritis of any kind• ME, fybromialgia, chronic fatigue• Allergies• Migraines & other headaches• Chronic cystitis• Skin problems: psoriasis, eczema, etc

BLOOD - BRAIN BARRIER

• Very selective in letting things through• Tight junctions & zonulin• Microbial toxins and autoimmune attack• Damaged blood – brain barrier• Toxins, microbes & antibodies get through• Impaired brain function leads to impaired

learning, behaviour, social skills & perception

• Epileptic seizures

Gut And Psychology Syndrome

Child Adult• AUTISM

• ADHD/ADD

• DYSLEXIA

• DYSPRAXIA

• LEARNING, BEHAVIOURAL, SOCIAL PROBLEMS

• SUBSTANCE

ABUSE

• DEPRESSION

• OBSESSIVE-

COMPULSIVE

• MANIC-

DEPRESSIVE

• SCHIZOPHRENIA

Epilepsy in children • 1% of population under the age of 20• 50% of children with mental problems• 70% - no cause is apparent

In vast majority of cases childhood epilepsy is due to toxicity coming from the gut

The treatment needs to concentrate on the gut health

GAPS Diet www.gaps.me

An Effective Probiotic

Address Nutritional Deficiencies

Detoxification

GAPS Nutritional Protocol