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Gavin Morrison Guy’s & St Thomas’ Hospitals, London, UK 28 th Politzer Society, Athens, 28 Sept 1 October 2011
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Page 1: Guy’s & St Thomas’ Hospitals, London, UK 28 Politzer ... · Gavin Morrison Guy’s & St Thomas’ Hospitals, London, UK 28th Politzer Society, Athens, 28 Sept – 1 October 2011

Gavin Morrison

Guyrsquos amp St Thomasrsquo Hospitals London UK

28th Politzer Society Athens 28 Sept ndash 1 October 2011

Otosclerosis amp Dizziness

Clinical Features

Aetiologies of Hydrops with otosclerosis

Temporal bone studies

Investigations

Managements When to Operate

Post operative

Hydrops

Simulated Hydrops

frac14 patients have some dizziness

Most do not have endolymphatic Hydrops

Types of Dizziness

Vague or brief dizziness - resolves after stapedectomy

BPPV ndash improves after Epley manoeuvre and after stapedectomy

True Endolymphatic Hydrops

Post Operative Endolymphatic Hydrops With fistula

Delayed

Simulated Post-op Hydrops

Fluctuant hearing levels

Menierersquos disease like Vertigo attacks

Aural Fullness tinnitus

Possible Hennebertrsquos sign

Audiogram

2007 Anita Pollak Zurich ndash 2 bones with hydrops due to otosclerotic foci obstructing endolymphatic duct (ref 1)

1982 Johnsson et al ndash 4 temporal bones with cochleo-saccular hydrops at otospongiotic foci fluid dynamics disturbed (ref 2)

1984 Liston Paparella et al (ref 3)

1990 Yoon Paparella Schachem 4128 (3) temporal bones with otosclerosis involved VA and had hydrops 10128 (78) had hydrops (ref 4)

1990 H Fisch ndash hydrops due to capsular otosclerosis causing duct obstruction 18 other cases without hydrops (5) ref 5

Last 200 referrals with Otosclerosis

Presentation with clinical picture of associated Hydrops in 11 cases

Incidence at presentation = 55

No suggestive history ndash no need

Suggestive History

Electrocochleography (70-85 sensitivity 2002 Shea Ear Clinic) ( ref6 )

MRI Scan

Cutting edge inner ear MRI (ref 7) Japan

3 Tesla novel phase sequences after Gd

Otology amp Neurotology 2008 29(4)571-572 Active Otospongiosis amp Hydrops (ref8)

Dilated Saccule or Reissnerrsquos membrane in contact with footplate

Intraoperative or post operative rupture

Confirm with ECOG Treat Medically

Fluoride Low salt Possible Diuretics vasodilators or Dexametasone

Avoid Stapedotomy Hearing aid BAHA Consider Stapes surgery after 2 years if no symptoms and

ECOG returned to normal Only consider stapes surgery if audiogram favourablehellip

If surgery undertaken ndash Mobilisation or posterior 13 small fenestra

Poor cochlear function amp Good hearing in other ear

Bone conduction worse than 45dB at 500 Hz and high frequency loss (House group 1984) (ref 9)

Early ndash with Perilymph Fistula Leak rate too fast for replacement through cochlear

aqueduct Low CSF pressure syndrome E Hydrops Management ndash SURGERY to close fistula

Delayed Hydrops

Otospongiotic obstruction of VAELS Inner ear scar tissue ndash obstruction (eg Saccule collapse) Non-suppurative labyrinthitis causes altered fluid

production drainage (ref 10)

Simulated Hydrops

Piston abutting or adherent to saccule ndash vertigo but not hydrops (-ve ECOG)

Endolymphatic Hydrops occurs secondary to Otosclerosis in about 8 cases presenting for treatment

If the history is suggestive ndash Undertake ECOG

Avoid Stapes Surgery with genuine active hydrops

Post-operative Hydrops can develop due to fistulization ndash if so seal it

Delayed Post-op hydrops is also described and requires conservative management

1 Otosclerosis associated with Meacuteniegraveres disease a histological study Advances in oto-rhino-laryngology Adv-Otorhinolaryngol 2007 vol 65 p 50-2 ISSN 0065-3071 Pollak-Anita

2 Cochlear and otoconial abnormalities in capsular otosclerosis with hydrops Johnsson LG Hawkins JE Jr Rouse RC Linthicum FH Jr Ovid MEDLINE(R) Annals of Otology Rhinology amp Laryngology - Supplement 973-15 1982 Sep-Oct

3 Extensive otosclerosis and endolymphatic hydrops histopathologic study of temporal bones Li W Schachern PA Paparella MM

4 Ovid MEDLINE(R) American Journal of Otolaryngology 15(2)158-61 1994 Mar-Apr Otosclerosis involving the vestibular aqueduct and Menieres disease Yoon TH Paparella MM Schachern PA Ovid MEDLINE(R) Otolaryngology - Head amp Neck Surgery 103(1)107-12 1990 Jul

5 Menieres symptoms resulting from bilateral otosclerotic occlusion of the endolymphatic duct an analysis of a causal relationship between otosclerosis and Menieres disease Franklin DJ Pollak A Fisch U Ovid MEDLINE(R) American Journal of Otology 11(2)135-40 1990 Mar

6 Transtympanic electrocochleography a 10-year experience Otology amp neurotology official publication of the American Otological Society American Neurotology Society (and) European Academy of Otology and Neurotology Otol-Neurotol Sep 2002 vol 23 no 5 p 799-805

7 Cutting edge of inner ear MRI Acta oto-laryngologica Supplementum Acta-Otolaryngol-Suppl Feb 2009 no 560 p 15-21 22 refs ISSN 0365-5237 Naganawa-Shinji Nakashima-Tsutomu

8 Cochlear otosclerosis amp endolymphatic hydrops Otology amp Neurotology 2008 29(4)571-572 A Makarem FH Linthicum

9 The effect of stepedectomy on hearing of patients with otosclerosis and menierersquos disease American J of Otology 19834323-326

10 Endolymphatic hydrops associated with otosclerosis The American journal of otology Am-J-Otol May 1994 vol 15 no 3 p 348-57 ISSN 0192-9763 Shea-J-J-Jr Ge-X Orchik-D-J

Page 2: Guy’s & St Thomas’ Hospitals, London, UK 28 Politzer ... · Gavin Morrison Guy’s & St Thomas’ Hospitals, London, UK 28th Politzer Society, Athens, 28 Sept – 1 October 2011

Otosclerosis amp Dizziness

Clinical Features

Aetiologies of Hydrops with otosclerosis

Temporal bone studies

Investigations

Managements When to Operate

Post operative

Hydrops

Simulated Hydrops

frac14 patients have some dizziness

Most do not have endolymphatic Hydrops

Types of Dizziness

Vague or brief dizziness - resolves after stapedectomy

BPPV ndash improves after Epley manoeuvre and after stapedectomy

True Endolymphatic Hydrops

Post Operative Endolymphatic Hydrops With fistula

Delayed

Simulated Post-op Hydrops

Fluctuant hearing levels

Menierersquos disease like Vertigo attacks

Aural Fullness tinnitus

Possible Hennebertrsquos sign

Audiogram

2007 Anita Pollak Zurich ndash 2 bones with hydrops due to otosclerotic foci obstructing endolymphatic duct (ref 1)

1982 Johnsson et al ndash 4 temporal bones with cochleo-saccular hydrops at otospongiotic foci fluid dynamics disturbed (ref 2)

1984 Liston Paparella et al (ref 3)

1990 Yoon Paparella Schachem 4128 (3) temporal bones with otosclerosis involved VA and had hydrops 10128 (78) had hydrops (ref 4)

1990 H Fisch ndash hydrops due to capsular otosclerosis causing duct obstruction 18 other cases without hydrops (5) ref 5

Last 200 referrals with Otosclerosis

Presentation with clinical picture of associated Hydrops in 11 cases

Incidence at presentation = 55

No suggestive history ndash no need

Suggestive History

Electrocochleography (70-85 sensitivity 2002 Shea Ear Clinic) ( ref6 )

MRI Scan

Cutting edge inner ear MRI (ref 7) Japan

3 Tesla novel phase sequences after Gd

Otology amp Neurotology 2008 29(4)571-572 Active Otospongiosis amp Hydrops (ref8)

Dilated Saccule or Reissnerrsquos membrane in contact with footplate

Intraoperative or post operative rupture

Confirm with ECOG Treat Medically

Fluoride Low salt Possible Diuretics vasodilators or Dexametasone

Avoid Stapedotomy Hearing aid BAHA Consider Stapes surgery after 2 years if no symptoms and

ECOG returned to normal Only consider stapes surgery if audiogram favourablehellip

If surgery undertaken ndash Mobilisation or posterior 13 small fenestra

Poor cochlear function amp Good hearing in other ear

Bone conduction worse than 45dB at 500 Hz and high frequency loss (House group 1984) (ref 9)

Early ndash with Perilymph Fistula Leak rate too fast for replacement through cochlear

aqueduct Low CSF pressure syndrome E Hydrops Management ndash SURGERY to close fistula

Delayed Hydrops

Otospongiotic obstruction of VAELS Inner ear scar tissue ndash obstruction (eg Saccule collapse) Non-suppurative labyrinthitis causes altered fluid

production drainage (ref 10)

Simulated Hydrops

Piston abutting or adherent to saccule ndash vertigo but not hydrops (-ve ECOG)

Endolymphatic Hydrops occurs secondary to Otosclerosis in about 8 cases presenting for treatment

If the history is suggestive ndash Undertake ECOG

Avoid Stapes Surgery with genuine active hydrops

Post-operative Hydrops can develop due to fistulization ndash if so seal it

Delayed Post-op hydrops is also described and requires conservative management

1 Otosclerosis associated with Meacuteniegraveres disease a histological study Advances in oto-rhino-laryngology Adv-Otorhinolaryngol 2007 vol 65 p 50-2 ISSN 0065-3071 Pollak-Anita

2 Cochlear and otoconial abnormalities in capsular otosclerosis with hydrops Johnsson LG Hawkins JE Jr Rouse RC Linthicum FH Jr Ovid MEDLINE(R) Annals of Otology Rhinology amp Laryngology - Supplement 973-15 1982 Sep-Oct

3 Extensive otosclerosis and endolymphatic hydrops histopathologic study of temporal bones Li W Schachern PA Paparella MM

4 Ovid MEDLINE(R) American Journal of Otolaryngology 15(2)158-61 1994 Mar-Apr Otosclerosis involving the vestibular aqueduct and Menieres disease Yoon TH Paparella MM Schachern PA Ovid MEDLINE(R) Otolaryngology - Head amp Neck Surgery 103(1)107-12 1990 Jul

5 Menieres symptoms resulting from bilateral otosclerotic occlusion of the endolymphatic duct an analysis of a causal relationship between otosclerosis and Menieres disease Franklin DJ Pollak A Fisch U Ovid MEDLINE(R) American Journal of Otology 11(2)135-40 1990 Mar

6 Transtympanic electrocochleography a 10-year experience Otology amp neurotology official publication of the American Otological Society American Neurotology Society (and) European Academy of Otology and Neurotology Otol-Neurotol Sep 2002 vol 23 no 5 p 799-805

7 Cutting edge of inner ear MRI Acta oto-laryngologica Supplementum Acta-Otolaryngol-Suppl Feb 2009 no 560 p 15-21 22 refs ISSN 0365-5237 Naganawa-Shinji Nakashima-Tsutomu

8 Cochlear otosclerosis amp endolymphatic hydrops Otology amp Neurotology 2008 29(4)571-572 A Makarem FH Linthicum

9 The effect of stepedectomy on hearing of patients with otosclerosis and menierersquos disease American J of Otology 19834323-326

10 Endolymphatic hydrops associated with otosclerosis The American journal of otology Am-J-Otol May 1994 vol 15 no 3 p 348-57 ISSN 0192-9763 Shea-J-J-Jr Ge-X Orchik-D-J

Page 3: Guy’s & St Thomas’ Hospitals, London, UK 28 Politzer ... · Gavin Morrison Guy’s & St Thomas’ Hospitals, London, UK 28th Politzer Society, Athens, 28 Sept – 1 October 2011

frac14 patients have some dizziness

Most do not have endolymphatic Hydrops

Types of Dizziness

Vague or brief dizziness - resolves after stapedectomy

BPPV ndash improves after Epley manoeuvre and after stapedectomy

True Endolymphatic Hydrops

Post Operative Endolymphatic Hydrops With fistula

Delayed

Simulated Post-op Hydrops

Fluctuant hearing levels

Menierersquos disease like Vertigo attacks

Aural Fullness tinnitus

Possible Hennebertrsquos sign

Audiogram

2007 Anita Pollak Zurich ndash 2 bones with hydrops due to otosclerotic foci obstructing endolymphatic duct (ref 1)

1982 Johnsson et al ndash 4 temporal bones with cochleo-saccular hydrops at otospongiotic foci fluid dynamics disturbed (ref 2)

1984 Liston Paparella et al (ref 3)

1990 Yoon Paparella Schachem 4128 (3) temporal bones with otosclerosis involved VA and had hydrops 10128 (78) had hydrops (ref 4)

1990 H Fisch ndash hydrops due to capsular otosclerosis causing duct obstruction 18 other cases without hydrops (5) ref 5

Last 200 referrals with Otosclerosis

Presentation with clinical picture of associated Hydrops in 11 cases

Incidence at presentation = 55

No suggestive history ndash no need

Suggestive History

Electrocochleography (70-85 sensitivity 2002 Shea Ear Clinic) ( ref6 )

MRI Scan

Cutting edge inner ear MRI (ref 7) Japan

3 Tesla novel phase sequences after Gd

Otology amp Neurotology 2008 29(4)571-572 Active Otospongiosis amp Hydrops (ref8)

Dilated Saccule or Reissnerrsquos membrane in contact with footplate

Intraoperative or post operative rupture

Confirm with ECOG Treat Medically

Fluoride Low salt Possible Diuretics vasodilators or Dexametasone

Avoid Stapedotomy Hearing aid BAHA Consider Stapes surgery after 2 years if no symptoms and

ECOG returned to normal Only consider stapes surgery if audiogram favourablehellip

If surgery undertaken ndash Mobilisation or posterior 13 small fenestra

Poor cochlear function amp Good hearing in other ear

Bone conduction worse than 45dB at 500 Hz and high frequency loss (House group 1984) (ref 9)

Early ndash with Perilymph Fistula Leak rate too fast for replacement through cochlear

aqueduct Low CSF pressure syndrome E Hydrops Management ndash SURGERY to close fistula

Delayed Hydrops

Otospongiotic obstruction of VAELS Inner ear scar tissue ndash obstruction (eg Saccule collapse) Non-suppurative labyrinthitis causes altered fluid

production drainage (ref 10)

Simulated Hydrops

Piston abutting or adherent to saccule ndash vertigo but not hydrops (-ve ECOG)

Endolymphatic Hydrops occurs secondary to Otosclerosis in about 8 cases presenting for treatment

If the history is suggestive ndash Undertake ECOG

Avoid Stapes Surgery with genuine active hydrops

Post-operative Hydrops can develop due to fistulization ndash if so seal it

Delayed Post-op hydrops is also described and requires conservative management

1 Otosclerosis associated with Meacuteniegraveres disease a histological study Advances in oto-rhino-laryngology Adv-Otorhinolaryngol 2007 vol 65 p 50-2 ISSN 0065-3071 Pollak-Anita

2 Cochlear and otoconial abnormalities in capsular otosclerosis with hydrops Johnsson LG Hawkins JE Jr Rouse RC Linthicum FH Jr Ovid MEDLINE(R) Annals of Otology Rhinology amp Laryngology - Supplement 973-15 1982 Sep-Oct

3 Extensive otosclerosis and endolymphatic hydrops histopathologic study of temporal bones Li W Schachern PA Paparella MM

4 Ovid MEDLINE(R) American Journal of Otolaryngology 15(2)158-61 1994 Mar-Apr Otosclerosis involving the vestibular aqueduct and Menieres disease Yoon TH Paparella MM Schachern PA Ovid MEDLINE(R) Otolaryngology - Head amp Neck Surgery 103(1)107-12 1990 Jul

5 Menieres symptoms resulting from bilateral otosclerotic occlusion of the endolymphatic duct an analysis of a causal relationship between otosclerosis and Menieres disease Franklin DJ Pollak A Fisch U Ovid MEDLINE(R) American Journal of Otology 11(2)135-40 1990 Mar

6 Transtympanic electrocochleography a 10-year experience Otology amp neurotology official publication of the American Otological Society American Neurotology Society (and) European Academy of Otology and Neurotology Otol-Neurotol Sep 2002 vol 23 no 5 p 799-805

7 Cutting edge of inner ear MRI Acta oto-laryngologica Supplementum Acta-Otolaryngol-Suppl Feb 2009 no 560 p 15-21 22 refs ISSN 0365-5237 Naganawa-Shinji Nakashima-Tsutomu

8 Cochlear otosclerosis amp endolymphatic hydrops Otology amp Neurotology 2008 29(4)571-572 A Makarem FH Linthicum

9 The effect of stepedectomy on hearing of patients with otosclerosis and menierersquos disease American J of Otology 19834323-326

10 Endolymphatic hydrops associated with otosclerosis The American journal of otology Am-J-Otol May 1994 vol 15 no 3 p 348-57 ISSN 0192-9763 Shea-J-J-Jr Ge-X Orchik-D-J

Page 4: Guy’s & St Thomas’ Hospitals, London, UK 28 Politzer ... · Gavin Morrison Guy’s & St Thomas’ Hospitals, London, UK 28th Politzer Society, Athens, 28 Sept – 1 October 2011

Fluctuant hearing levels

Menierersquos disease like Vertigo attacks

Aural Fullness tinnitus

Possible Hennebertrsquos sign

Audiogram

2007 Anita Pollak Zurich ndash 2 bones with hydrops due to otosclerotic foci obstructing endolymphatic duct (ref 1)

1982 Johnsson et al ndash 4 temporal bones with cochleo-saccular hydrops at otospongiotic foci fluid dynamics disturbed (ref 2)

1984 Liston Paparella et al (ref 3)

1990 Yoon Paparella Schachem 4128 (3) temporal bones with otosclerosis involved VA and had hydrops 10128 (78) had hydrops (ref 4)

1990 H Fisch ndash hydrops due to capsular otosclerosis causing duct obstruction 18 other cases without hydrops (5) ref 5

Last 200 referrals with Otosclerosis

Presentation with clinical picture of associated Hydrops in 11 cases

Incidence at presentation = 55

No suggestive history ndash no need

Suggestive History

Electrocochleography (70-85 sensitivity 2002 Shea Ear Clinic) ( ref6 )

MRI Scan

Cutting edge inner ear MRI (ref 7) Japan

3 Tesla novel phase sequences after Gd

Otology amp Neurotology 2008 29(4)571-572 Active Otospongiosis amp Hydrops (ref8)

Dilated Saccule or Reissnerrsquos membrane in contact with footplate

Intraoperative or post operative rupture

Confirm with ECOG Treat Medically

Fluoride Low salt Possible Diuretics vasodilators or Dexametasone

Avoid Stapedotomy Hearing aid BAHA Consider Stapes surgery after 2 years if no symptoms and

ECOG returned to normal Only consider stapes surgery if audiogram favourablehellip

If surgery undertaken ndash Mobilisation or posterior 13 small fenestra

Poor cochlear function amp Good hearing in other ear

Bone conduction worse than 45dB at 500 Hz and high frequency loss (House group 1984) (ref 9)

Early ndash with Perilymph Fistula Leak rate too fast for replacement through cochlear

aqueduct Low CSF pressure syndrome E Hydrops Management ndash SURGERY to close fistula

Delayed Hydrops

Otospongiotic obstruction of VAELS Inner ear scar tissue ndash obstruction (eg Saccule collapse) Non-suppurative labyrinthitis causes altered fluid

production drainage (ref 10)

Simulated Hydrops

Piston abutting or adherent to saccule ndash vertigo but not hydrops (-ve ECOG)

Endolymphatic Hydrops occurs secondary to Otosclerosis in about 8 cases presenting for treatment

If the history is suggestive ndash Undertake ECOG

Avoid Stapes Surgery with genuine active hydrops

Post-operative Hydrops can develop due to fistulization ndash if so seal it

Delayed Post-op hydrops is also described and requires conservative management

1 Otosclerosis associated with Meacuteniegraveres disease a histological study Advances in oto-rhino-laryngology Adv-Otorhinolaryngol 2007 vol 65 p 50-2 ISSN 0065-3071 Pollak-Anita

2 Cochlear and otoconial abnormalities in capsular otosclerosis with hydrops Johnsson LG Hawkins JE Jr Rouse RC Linthicum FH Jr Ovid MEDLINE(R) Annals of Otology Rhinology amp Laryngology - Supplement 973-15 1982 Sep-Oct

3 Extensive otosclerosis and endolymphatic hydrops histopathologic study of temporal bones Li W Schachern PA Paparella MM

4 Ovid MEDLINE(R) American Journal of Otolaryngology 15(2)158-61 1994 Mar-Apr Otosclerosis involving the vestibular aqueduct and Menieres disease Yoon TH Paparella MM Schachern PA Ovid MEDLINE(R) Otolaryngology - Head amp Neck Surgery 103(1)107-12 1990 Jul

5 Menieres symptoms resulting from bilateral otosclerotic occlusion of the endolymphatic duct an analysis of a causal relationship between otosclerosis and Menieres disease Franklin DJ Pollak A Fisch U Ovid MEDLINE(R) American Journal of Otology 11(2)135-40 1990 Mar

6 Transtympanic electrocochleography a 10-year experience Otology amp neurotology official publication of the American Otological Society American Neurotology Society (and) European Academy of Otology and Neurotology Otol-Neurotol Sep 2002 vol 23 no 5 p 799-805

7 Cutting edge of inner ear MRI Acta oto-laryngologica Supplementum Acta-Otolaryngol-Suppl Feb 2009 no 560 p 15-21 22 refs ISSN 0365-5237 Naganawa-Shinji Nakashima-Tsutomu

8 Cochlear otosclerosis amp endolymphatic hydrops Otology amp Neurotology 2008 29(4)571-572 A Makarem FH Linthicum

9 The effect of stepedectomy on hearing of patients with otosclerosis and menierersquos disease American J of Otology 19834323-326

10 Endolymphatic hydrops associated with otosclerosis The American journal of otology Am-J-Otol May 1994 vol 15 no 3 p 348-57 ISSN 0192-9763 Shea-J-J-Jr Ge-X Orchik-D-J

Page 5: Guy’s & St Thomas’ Hospitals, London, UK 28 Politzer ... · Gavin Morrison Guy’s & St Thomas’ Hospitals, London, UK 28th Politzer Society, Athens, 28 Sept – 1 October 2011

2007 Anita Pollak Zurich ndash 2 bones with hydrops due to otosclerotic foci obstructing endolymphatic duct (ref 1)

1982 Johnsson et al ndash 4 temporal bones with cochleo-saccular hydrops at otospongiotic foci fluid dynamics disturbed (ref 2)

1984 Liston Paparella et al (ref 3)

1990 Yoon Paparella Schachem 4128 (3) temporal bones with otosclerosis involved VA and had hydrops 10128 (78) had hydrops (ref 4)

1990 H Fisch ndash hydrops due to capsular otosclerosis causing duct obstruction 18 other cases without hydrops (5) ref 5

Last 200 referrals with Otosclerosis

Presentation with clinical picture of associated Hydrops in 11 cases

Incidence at presentation = 55

No suggestive history ndash no need

Suggestive History

Electrocochleography (70-85 sensitivity 2002 Shea Ear Clinic) ( ref6 )

MRI Scan

Cutting edge inner ear MRI (ref 7) Japan

3 Tesla novel phase sequences after Gd

Otology amp Neurotology 2008 29(4)571-572 Active Otospongiosis amp Hydrops (ref8)

Dilated Saccule or Reissnerrsquos membrane in contact with footplate

Intraoperative or post operative rupture

Confirm with ECOG Treat Medically

Fluoride Low salt Possible Diuretics vasodilators or Dexametasone

Avoid Stapedotomy Hearing aid BAHA Consider Stapes surgery after 2 years if no symptoms and

ECOG returned to normal Only consider stapes surgery if audiogram favourablehellip

If surgery undertaken ndash Mobilisation or posterior 13 small fenestra

Poor cochlear function amp Good hearing in other ear

Bone conduction worse than 45dB at 500 Hz and high frequency loss (House group 1984) (ref 9)

Early ndash with Perilymph Fistula Leak rate too fast for replacement through cochlear

aqueduct Low CSF pressure syndrome E Hydrops Management ndash SURGERY to close fistula

Delayed Hydrops

Otospongiotic obstruction of VAELS Inner ear scar tissue ndash obstruction (eg Saccule collapse) Non-suppurative labyrinthitis causes altered fluid

production drainage (ref 10)

Simulated Hydrops

Piston abutting or adherent to saccule ndash vertigo but not hydrops (-ve ECOG)

Endolymphatic Hydrops occurs secondary to Otosclerosis in about 8 cases presenting for treatment

If the history is suggestive ndash Undertake ECOG

Avoid Stapes Surgery with genuine active hydrops

Post-operative Hydrops can develop due to fistulization ndash if so seal it

Delayed Post-op hydrops is also described and requires conservative management

1 Otosclerosis associated with Meacuteniegraveres disease a histological study Advances in oto-rhino-laryngology Adv-Otorhinolaryngol 2007 vol 65 p 50-2 ISSN 0065-3071 Pollak-Anita

2 Cochlear and otoconial abnormalities in capsular otosclerosis with hydrops Johnsson LG Hawkins JE Jr Rouse RC Linthicum FH Jr Ovid MEDLINE(R) Annals of Otology Rhinology amp Laryngology - Supplement 973-15 1982 Sep-Oct

3 Extensive otosclerosis and endolymphatic hydrops histopathologic study of temporal bones Li W Schachern PA Paparella MM

4 Ovid MEDLINE(R) American Journal of Otolaryngology 15(2)158-61 1994 Mar-Apr Otosclerosis involving the vestibular aqueduct and Menieres disease Yoon TH Paparella MM Schachern PA Ovid MEDLINE(R) Otolaryngology - Head amp Neck Surgery 103(1)107-12 1990 Jul

5 Menieres symptoms resulting from bilateral otosclerotic occlusion of the endolymphatic duct an analysis of a causal relationship between otosclerosis and Menieres disease Franklin DJ Pollak A Fisch U Ovid MEDLINE(R) American Journal of Otology 11(2)135-40 1990 Mar

6 Transtympanic electrocochleography a 10-year experience Otology amp neurotology official publication of the American Otological Society American Neurotology Society (and) European Academy of Otology and Neurotology Otol-Neurotol Sep 2002 vol 23 no 5 p 799-805

7 Cutting edge of inner ear MRI Acta oto-laryngologica Supplementum Acta-Otolaryngol-Suppl Feb 2009 no 560 p 15-21 22 refs ISSN 0365-5237 Naganawa-Shinji Nakashima-Tsutomu

8 Cochlear otosclerosis amp endolymphatic hydrops Otology amp Neurotology 2008 29(4)571-572 A Makarem FH Linthicum

9 The effect of stepedectomy on hearing of patients with otosclerosis and menierersquos disease American J of Otology 19834323-326

10 Endolymphatic hydrops associated with otosclerosis The American journal of otology Am-J-Otol May 1994 vol 15 no 3 p 348-57 ISSN 0192-9763 Shea-J-J-Jr Ge-X Orchik-D-J

Page 6: Guy’s & St Thomas’ Hospitals, London, UK 28 Politzer ... · Gavin Morrison Guy’s & St Thomas’ Hospitals, London, UK 28th Politzer Society, Athens, 28 Sept – 1 October 2011

Last 200 referrals with Otosclerosis

Presentation with clinical picture of associated Hydrops in 11 cases

Incidence at presentation = 55

No suggestive history ndash no need

Suggestive History

Electrocochleography (70-85 sensitivity 2002 Shea Ear Clinic) ( ref6 )

MRI Scan

Cutting edge inner ear MRI (ref 7) Japan

3 Tesla novel phase sequences after Gd

Otology amp Neurotology 2008 29(4)571-572 Active Otospongiosis amp Hydrops (ref8)

Dilated Saccule or Reissnerrsquos membrane in contact with footplate

Intraoperative or post operative rupture

Confirm with ECOG Treat Medically

Fluoride Low salt Possible Diuretics vasodilators or Dexametasone

Avoid Stapedotomy Hearing aid BAHA Consider Stapes surgery after 2 years if no symptoms and

ECOG returned to normal Only consider stapes surgery if audiogram favourablehellip

If surgery undertaken ndash Mobilisation or posterior 13 small fenestra

Poor cochlear function amp Good hearing in other ear

Bone conduction worse than 45dB at 500 Hz and high frequency loss (House group 1984) (ref 9)

Early ndash with Perilymph Fistula Leak rate too fast for replacement through cochlear

aqueduct Low CSF pressure syndrome E Hydrops Management ndash SURGERY to close fistula

Delayed Hydrops

Otospongiotic obstruction of VAELS Inner ear scar tissue ndash obstruction (eg Saccule collapse) Non-suppurative labyrinthitis causes altered fluid

production drainage (ref 10)

Simulated Hydrops

Piston abutting or adherent to saccule ndash vertigo but not hydrops (-ve ECOG)

Endolymphatic Hydrops occurs secondary to Otosclerosis in about 8 cases presenting for treatment

If the history is suggestive ndash Undertake ECOG

Avoid Stapes Surgery with genuine active hydrops

Post-operative Hydrops can develop due to fistulization ndash if so seal it

Delayed Post-op hydrops is also described and requires conservative management

1 Otosclerosis associated with Meacuteniegraveres disease a histological study Advances in oto-rhino-laryngology Adv-Otorhinolaryngol 2007 vol 65 p 50-2 ISSN 0065-3071 Pollak-Anita

2 Cochlear and otoconial abnormalities in capsular otosclerosis with hydrops Johnsson LG Hawkins JE Jr Rouse RC Linthicum FH Jr Ovid MEDLINE(R) Annals of Otology Rhinology amp Laryngology - Supplement 973-15 1982 Sep-Oct

3 Extensive otosclerosis and endolymphatic hydrops histopathologic study of temporal bones Li W Schachern PA Paparella MM

4 Ovid MEDLINE(R) American Journal of Otolaryngology 15(2)158-61 1994 Mar-Apr Otosclerosis involving the vestibular aqueduct and Menieres disease Yoon TH Paparella MM Schachern PA Ovid MEDLINE(R) Otolaryngology - Head amp Neck Surgery 103(1)107-12 1990 Jul

5 Menieres symptoms resulting from bilateral otosclerotic occlusion of the endolymphatic duct an analysis of a causal relationship between otosclerosis and Menieres disease Franklin DJ Pollak A Fisch U Ovid MEDLINE(R) American Journal of Otology 11(2)135-40 1990 Mar

6 Transtympanic electrocochleography a 10-year experience Otology amp neurotology official publication of the American Otological Society American Neurotology Society (and) European Academy of Otology and Neurotology Otol-Neurotol Sep 2002 vol 23 no 5 p 799-805

7 Cutting edge of inner ear MRI Acta oto-laryngologica Supplementum Acta-Otolaryngol-Suppl Feb 2009 no 560 p 15-21 22 refs ISSN 0365-5237 Naganawa-Shinji Nakashima-Tsutomu

8 Cochlear otosclerosis amp endolymphatic hydrops Otology amp Neurotology 2008 29(4)571-572 A Makarem FH Linthicum

9 The effect of stepedectomy on hearing of patients with otosclerosis and menierersquos disease American J of Otology 19834323-326

10 Endolymphatic hydrops associated with otosclerosis The American journal of otology Am-J-Otol May 1994 vol 15 no 3 p 348-57 ISSN 0192-9763 Shea-J-J-Jr Ge-X Orchik-D-J

Page 7: Guy’s & St Thomas’ Hospitals, London, UK 28 Politzer ... · Gavin Morrison Guy’s & St Thomas’ Hospitals, London, UK 28th Politzer Society, Athens, 28 Sept – 1 October 2011

No suggestive history ndash no need

Suggestive History

Electrocochleography (70-85 sensitivity 2002 Shea Ear Clinic) ( ref6 )

MRI Scan

Cutting edge inner ear MRI (ref 7) Japan

3 Tesla novel phase sequences after Gd

Otology amp Neurotology 2008 29(4)571-572 Active Otospongiosis amp Hydrops (ref8)

Dilated Saccule or Reissnerrsquos membrane in contact with footplate

Intraoperative or post operative rupture

Confirm with ECOG Treat Medically

Fluoride Low salt Possible Diuretics vasodilators or Dexametasone

Avoid Stapedotomy Hearing aid BAHA Consider Stapes surgery after 2 years if no symptoms and

ECOG returned to normal Only consider stapes surgery if audiogram favourablehellip

If surgery undertaken ndash Mobilisation or posterior 13 small fenestra

Poor cochlear function amp Good hearing in other ear

Bone conduction worse than 45dB at 500 Hz and high frequency loss (House group 1984) (ref 9)

Early ndash with Perilymph Fistula Leak rate too fast for replacement through cochlear

aqueduct Low CSF pressure syndrome E Hydrops Management ndash SURGERY to close fistula

Delayed Hydrops

Otospongiotic obstruction of VAELS Inner ear scar tissue ndash obstruction (eg Saccule collapse) Non-suppurative labyrinthitis causes altered fluid

production drainage (ref 10)

Simulated Hydrops

Piston abutting or adherent to saccule ndash vertigo but not hydrops (-ve ECOG)

Endolymphatic Hydrops occurs secondary to Otosclerosis in about 8 cases presenting for treatment

If the history is suggestive ndash Undertake ECOG

Avoid Stapes Surgery with genuine active hydrops

Post-operative Hydrops can develop due to fistulization ndash if so seal it

Delayed Post-op hydrops is also described and requires conservative management

1 Otosclerosis associated with Meacuteniegraveres disease a histological study Advances in oto-rhino-laryngology Adv-Otorhinolaryngol 2007 vol 65 p 50-2 ISSN 0065-3071 Pollak-Anita

2 Cochlear and otoconial abnormalities in capsular otosclerosis with hydrops Johnsson LG Hawkins JE Jr Rouse RC Linthicum FH Jr Ovid MEDLINE(R) Annals of Otology Rhinology amp Laryngology - Supplement 973-15 1982 Sep-Oct

3 Extensive otosclerosis and endolymphatic hydrops histopathologic study of temporal bones Li W Schachern PA Paparella MM

4 Ovid MEDLINE(R) American Journal of Otolaryngology 15(2)158-61 1994 Mar-Apr Otosclerosis involving the vestibular aqueduct and Menieres disease Yoon TH Paparella MM Schachern PA Ovid MEDLINE(R) Otolaryngology - Head amp Neck Surgery 103(1)107-12 1990 Jul

5 Menieres symptoms resulting from bilateral otosclerotic occlusion of the endolymphatic duct an analysis of a causal relationship between otosclerosis and Menieres disease Franklin DJ Pollak A Fisch U Ovid MEDLINE(R) American Journal of Otology 11(2)135-40 1990 Mar

6 Transtympanic electrocochleography a 10-year experience Otology amp neurotology official publication of the American Otological Society American Neurotology Society (and) European Academy of Otology and Neurotology Otol-Neurotol Sep 2002 vol 23 no 5 p 799-805

7 Cutting edge of inner ear MRI Acta oto-laryngologica Supplementum Acta-Otolaryngol-Suppl Feb 2009 no 560 p 15-21 22 refs ISSN 0365-5237 Naganawa-Shinji Nakashima-Tsutomu

8 Cochlear otosclerosis amp endolymphatic hydrops Otology amp Neurotology 2008 29(4)571-572 A Makarem FH Linthicum

9 The effect of stepedectomy on hearing of patients with otosclerosis and menierersquos disease American J of Otology 19834323-326

10 Endolymphatic hydrops associated with otosclerosis The American journal of otology Am-J-Otol May 1994 vol 15 no 3 p 348-57 ISSN 0192-9763 Shea-J-J-Jr Ge-X Orchik-D-J

Page 8: Guy’s & St Thomas’ Hospitals, London, UK 28 Politzer ... · Gavin Morrison Guy’s & St Thomas’ Hospitals, London, UK 28th Politzer Society, Athens, 28 Sept – 1 October 2011

Otology amp Neurotology 2008 29(4)571-572 Active Otospongiosis amp Hydrops (ref8)

Dilated Saccule or Reissnerrsquos membrane in contact with footplate

Intraoperative or post operative rupture

Confirm with ECOG Treat Medically

Fluoride Low salt Possible Diuretics vasodilators or Dexametasone

Avoid Stapedotomy Hearing aid BAHA Consider Stapes surgery after 2 years if no symptoms and

ECOG returned to normal Only consider stapes surgery if audiogram favourablehellip

If surgery undertaken ndash Mobilisation or posterior 13 small fenestra

Poor cochlear function amp Good hearing in other ear

Bone conduction worse than 45dB at 500 Hz and high frequency loss (House group 1984) (ref 9)

Early ndash with Perilymph Fistula Leak rate too fast for replacement through cochlear

aqueduct Low CSF pressure syndrome E Hydrops Management ndash SURGERY to close fistula

Delayed Hydrops

Otospongiotic obstruction of VAELS Inner ear scar tissue ndash obstruction (eg Saccule collapse) Non-suppurative labyrinthitis causes altered fluid

production drainage (ref 10)

Simulated Hydrops

Piston abutting or adherent to saccule ndash vertigo but not hydrops (-ve ECOG)

Endolymphatic Hydrops occurs secondary to Otosclerosis in about 8 cases presenting for treatment

If the history is suggestive ndash Undertake ECOG

Avoid Stapes Surgery with genuine active hydrops

Post-operative Hydrops can develop due to fistulization ndash if so seal it

Delayed Post-op hydrops is also described and requires conservative management

1 Otosclerosis associated with Meacuteniegraveres disease a histological study Advances in oto-rhino-laryngology Adv-Otorhinolaryngol 2007 vol 65 p 50-2 ISSN 0065-3071 Pollak-Anita

2 Cochlear and otoconial abnormalities in capsular otosclerosis with hydrops Johnsson LG Hawkins JE Jr Rouse RC Linthicum FH Jr Ovid MEDLINE(R) Annals of Otology Rhinology amp Laryngology - Supplement 973-15 1982 Sep-Oct

3 Extensive otosclerosis and endolymphatic hydrops histopathologic study of temporal bones Li W Schachern PA Paparella MM

4 Ovid MEDLINE(R) American Journal of Otolaryngology 15(2)158-61 1994 Mar-Apr Otosclerosis involving the vestibular aqueduct and Menieres disease Yoon TH Paparella MM Schachern PA Ovid MEDLINE(R) Otolaryngology - Head amp Neck Surgery 103(1)107-12 1990 Jul

5 Menieres symptoms resulting from bilateral otosclerotic occlusion of the endolymphatic duct an analysis of a causal relationship between otosclerosis and Menieres disease Franklin DJ Pollak A Fisch U Ovid MEDLINE(R) American Journal of Otology 11(2)135-40 1990 Mar

6 Transtympanic electrocochleography a 10-year experience Otology amp neurotology official publication of the American Otological Society American Neurotology Society (and) European Academy of Otology and Neurotology Otol-Neurotol Sep 2002 vol 23 no 5 p 799-805

7 Cutting edge of inner ear MRI Acta oto-laryngologica Supplementum Acta-Otolaryngol-Suppl Feb 2009 no 560 p 15-21 22 refs ISSN 0365-5237 Naganawa-Shinji Nakashima-Tsutomu

8 Cochlear otosclerosis amp endolymphatic hydrops Otology amp Neurotology 2008 29(4)571-572 A Makarem FH Linthicum

9 The effect of stepedectomy on hearing of patients with otosclerosis and menierersquos disease American J of Otology 19834323-326

10 Endolymphatic hydrops associated with otosclerosis The American journal of otology Am-J-Otol May 1994 vol 15 no 3 p 348-57 ISSN 0192-9763 Shea-J-J-Jr Ge-X Orchik-D-J

Page 9: Guy’s & St Thomas’ Hospitals, London, UK 28 Politzer ... · Gavin Morrison Guy’s & St Thomas’ Hospitals, London, UK 28th Politzer Society, Athens, 28 Sept – 1 October 2011

Dilated Saccule or Reissnerrsquos membrane in contact with footplate

Intraoperative or post operative rupture

Confirm with ECOG Treat Medically

Fluoride Low salt Possible Diuretics vasodilators or Dexametasone

Avoid Stapedotomy Hearing aid BAHA Consider Stapes surgery after 2 years if no symptoms and

ECOG returned to normal Only consider stapes surgery if audiogram favourablehellip

If surgery undertaken ndash Mobilisation or posterior 13 small fenestra

Poor cochlear function amp Good hearing in other ear

Bone conduction worse than 45dB at 500 Hz and high frequency loss (House group 1984) (ref 9)

Early ndash with Perilymph Fistula Leak rate too fast for replacement through cochlear

aqueduct Low CSF pressure syndrome E Hydrops Management ndash SURGERY to close fistula

Delayed Hydrops

Otospongiotic obstruction of VAELS Inner ear scar tissue ndash obstruction (eg Saccule collapse) Non-suppurative labyrinthitis causes altered fluid

production drainage (ref 10)

Simulated Hydrops

Piston abutting or adherent to saccule ndash vertigo but not hydrops (-ve ECOG)

Endolymphatic Hydrops occurs secondary to Otosclerosis in about 8 cases presenting for treatment

If the history is suggestive ndash Undertake ECOG

Avoid Stapes Surgery with genuine active hydrops

Post-operative Hydrops can develop due to fistulization ndash if so seal it

Delayed Post-op hydrops is also described and requires conservative management

1 Otosclerosis associated with Meacuteniegraveres disease a histological study Advances in oto-rhino-laryngology Adv-Otorhinolaryngol 2007 vol 65 p 50-2 ISSN 0065-3071 Pollak-Anita

2 Cochlear and otoconial abnormalities in capsular otosclerosis with hydrops Johnsson LG Hawkins JE Jr Rouse RC Linthicum FH Jr Ovid MEDLINE(R) Annals of Otology Rhinology amp Laryngology - Supplement 973-15 1982 Sep-Oct

3 Extensive otosclerosis and endolymphatic hydrops histopathologic study of temporal bones Li W Schachern PA Paparella MM

4 Ovid MEDLINE(R) American Journal of Otolaryngology 15(2)158-61 1994 Mar-Apr Otosclerosis involving the vestibular aqueduct and Menieres disease Yoon TH Paparella MM Schachern PA Ovid MEDLINE(R) Otolaryngology - Head amp Neck Surgery 103(1)107-12 1990 Jul

5 Menieres symptoms resulting from bilateral otosclerotic occlusion of the endolymphatic duct an analysis of a causal relationship between otosclerosis and Menieres disease Franklin DJ Pollak A Fisch U Ovid MEDLINE(R) American Journal of Otology 11(2)135-40 1990 Mar

6 Transtympanic electrocochleography a 10-year experience Otology amp neurotology official publication of the American Otological Society American Neurotology Society (and) European Academy of Otology and Neurotology Otol-Neurotol Sep 2002 vol 23 no 5 p 799-805

7 Cutting edge of inner ear MRI Acta oto-laryngologica Supplementum Acta-Otolaryngol-Suppl Feb 2009 no 560 p 15-21 22 refs ISSN 0365-5237 Naganawa-Shinji Nakashima-Tsutomu

8 Cochlear otosclerosis amp endolymphatic hydrops Otology amp Neurotology 2008 29(4)571-572 A Makarem FH Linthicum

9 The effect of stepedectomy on hearing of patients with otosclerosis and menierersquos disease American J of Otology 19834323-326

10 Endolymphatic hydrops associated with otosclerosis The American journal of otology Am-J-Otol May 1994 vol 15 no 3 p 348-57 ISSN 0192-9763 Shea-J-J-Jr Ge-X Orchik-D-J

Page 10: Guy’s & St Thomas’ Hospitals, London, UK 28 Politzer ... · Gavin Morrison Guy’s & St Thomas’ Hospitals, London, UK 28th Politzer Society, Athens, 28 Sept – 1 October 2011

Confirm with ECOG Treat Medically

Fluoride Low salt Possible Diuretics vasodilators or Dexametasone

Avoid Stapedotomy Hearing aid BAHA Consider Stapes surgery after 2 years if no symptoms and

ECOG returned to normal Only consider stapes surgery if audiogram favourablehellip

If surgery undertaken ndash Mobilisation or posterior 13 small fenestra

Poor cochlear function amp Good hearing in other ear

Bone conduction worse than 45dB at 500 Hz and high frequency loss (House group 1984) (ref 9)

Early ndash with Perilymph Fistula Leak rate too fast for replacement through cochlear

aqueduct Low CSF pressure syndrome E Hydrops Management ndash SURGERY to close fistula

Delayed Hydrops

Otospongiotic obstruction of VAELS Inner ear scar tissue ndash obstruction (eg Saccule collapse) Non-suppurative labyrinthitis causes altered fluid

production drainage (ref 10)

Simulated Hydrops

Piston abutting or adherent to saccule ndash vertigo but not hydrops (-ve ECOG)

Endolymphatic Hydrops occurs secondary to Otosclerosis in about 8 cases presenting for treatment

If the history is suggestive ndash Undertake ECOG

Avoid Stapes Surgery with genuine active hydrops

Post-operative Hydrops can develop due to fistulization ndash if so seal it

Delayed Post-op hydrops is also described and requires conservative management

1 Otosclerosis associated with Meacuteniegraveres disease a histological study Advances in oto-rhino-laryngology Adv-Otorhinolaryngol 2007 vol 65 p 50-2 ISSN 0065-3071 Pollak-Anita

2 Cochlear and otoconial abnormalities in capsular otosclerosis with hydrops Johnsson LG Hawkins JE Jr Rouse RC Linthicum FH Jr Ovid MEDLINE(R) Annals of Otology Rhinology amp Laryngology - Supplement 973-15 1982 Sep-Oct

3 Extensive otosclerosis and endolymphatic hydrops histopathologic study of temporal bones Li W Schachern PA Paparella MM

4 Ovid MEDLINE(R) American Journal of Otolaryngology 15(2)158-61 1994 Mar-Apr Otosclerosis involving the vestibular aqueduct and Menieres disease Yoon TH Paparella MM Schachern PA Ovid MEDLINE(R) Otolaryngology - Head amp Neck Surgery 103(1)107-12 1990 Jul

5 Menieres symptoms resulting from bilateral otosclerotic occlusion of the endolymphatic duct an analysis of a causal relationship between otosclerosis and Menieres disease Franklin DJ Pollak A Fisch U Ovid MEDLINE(R) American Journal of Otology 11(2)135-40 1990 Mar

6 Transtympanic electrocochleography a 10-year experience Otology amp neurotology official publication of the American Otological Society American Neurotology Society (and) European Academy of Otology and Neurotology Otol-Neurotol Sep 2002 vol 23 no 5 p 799-805

7 Cutting edge of inner ear MRI Acta oto-laryngologica Supplementum Acta-Otolaryngol-Suppl Feb 2009 no 560 p 15-21 22 refs ISSN 0365-5237 Naganawa-Shinji Nakashima-Tsutomu

8 Cochlear otosclerosis amp endolymphatic hydrops Otology amp Neurotology 2008 29(4)571-572 A Makarem FH Linthicum

9 The effect of stepedectomy on hearing of patients with otosclerosis and menierersquos disease American J of Otology 19834323-326

10 Endolymphatic hydrops associated with otosclerosis The American journal of otology Am-J-Otol May 1994 vol 15 no 3 p 348-57 ISSN 0192-9763 Shea-J-J-Jr Ge-X Orchik-D-J

Page 11: Guy’s & St Thomas’ Hospitals, London, UK 28 Politzer ... · Gavin Morrison Guy’s & St Thomas’ Hospitals, London, UK 28th Politzer Society, Athens, 28 Sept – 1 October 2011

Poor cochlear function amp Good hearing in other ear

Bone conduction worse than 45dB at 500 Hz and high frequency loss (House group 1984) (ref 9)

Early ndash with Perilymph Fistula Leak rate too fast for replacement through cochlear

aqueduct Low CSF pressure syndrome E Hydrops Management ndash SURGERY to close fistula

Delayed Hydrops

Otospongiotic obstruction of VAELS Inner ear scar tissue ndash obstruction (eg Saccule collapse) Non-suppurative labyrinthitis causes altered fluid

production drainage (ref 10)

Simulated Hydrops

Piston abutting or adherent to saccule ndash vertigo but not hydrops (-ve ECOG)

Endolymphatic Hydrops occurs secondary to Otosclerosis in about 8 cases presenting for treatment

If the history is suggestive ndash Undertake ECOG

Avoid Stapes Surgery with genuine active hydrops

Post-operative Hydrops can develop due to fistulization ndash if so seal it

Delayed Post-op hydrops is also described and requires conservative management

1 Otosclerosis associated with Meacuteniegraveres disease a histological study Advances in oto-rhino-laryngology Adv-Otorhinolaryngol 2007 vol 65 p 50-2 ISSN 0065-3071 Pollak-Anita

2 Cochlear and otoconial abnormalities in capsular otosclerosis with hydrops Johnsson LG Hawkins JE Jr Rouse RC Linthicum FH Jr Ovid MEDLINE(R) Annals of Otology Rhinology amp Laryngology - Supplement 973-15 1982 Sep-Oct

3 Extensive otosclerosis and endolymphatic hydrops histopathologic study of temporal bones Li W Schachern PA Paparella MM

4 Ovid MEDLINE(R) American Journal of Otolaryngology 15(2)158-61 1994 Mar-Apr Otosclerosis involving the vestibular aqueduct and Menieres disease Yoon TH Paparella MM Schachern PA Ovid MEDLINE(R) Otolaryngology - Head amp Neck Surgery 103(1)107-12 1990 Jul

5 Menieres symptoms resulting from bilateral otosclerotic occlusion of the endolymphatic duct an analysis of a causal relationship between otosclerosis and Menieres disease Franklin DJ Pollak A Fisch U Ovid MEDLINE(R) American Journal of Otology 11(2)135-40 1990 Mar

6 Transtympanic electrocochleography a 10-year experience Otology amp neurotology official publication of the American Otological Society American Neurotology Society (and) European Academy of Otology and Neurotology Otol-Neurotol Sep 2002 vol 23 no 5 p 799-805

7 Cutting edge of inner ear MRI Acta oto-laryngologica Supplementum Acta-Otolaryngol-Suppl Feb 2009 no 560 p 15-21 22 refs ISSN 0365-5237 Naganawa-Shinji Nakashima-Tsutomu

8 Cochlear otosclerosis amp endolymphatic hydrops Otology amp Neurotology 2008 29(4)571-572 A Makarem FH Linthicum

9 The effect of stepedectomy on hearing of patients with otosclerosis and menierersquos disease American J of Otology 19834323-326

10 Endolymphatic hydrops associated with otosclerosis The American journal of otology Am-J-Otol May 1994 vol 15 no 3 p 348-57 ISSN 0192-9763 Shea-J-J-Jr Ge-X Orchik-D-J

Page 12: Guy’s & St Thomas’ Hospitals, London, UK 28 Politzer ... · Gavin Morrison Guy’s & St Thomas’ Hospitals, London, UK 28th Politzer Society, Athens, 28 Sept – 1 October 2011

Early ndash with Perilymph Fistula Leak rate too fast for replacement through cochlear

aqueduct Low CSF pressure syndrome E Hydrops Management ndash SURGERY to close fistula

Delayed Hydrops

Otospongiotic obstruction of VAELS Inner ear scar tissue ndash obstruction (eg Saccule collapse) Non-suppurative labyrinthitis causes altered fluid

production drainage (ref 10)

Simulated Hydrops

Piston abutting or adherent to saccule ndash vertigo but not hydrops (-ve ECOG)

Endolymphatic Hydrops occurs secondary to Otosclerosis in about 8 cases presenting for treatment

If the history is suggestive ndash Undertake ECOG

Avoid Stapes Surgery with genuine active hydrops

Post-operative Hydrops can develop due to fistulization ndash if so seal it

Delayed Post-op hydrops is also described and requires conservative management

1 Otosclerosis associated with Meacuteniegraveres disease a histological study Advances in oto-rhino-laryngology Adv-Otorhinolaryngol 2007 vol 65 p 50-2 ISSN 0065-3071 Pollak-Anita

2 Cochlear and otoconial abnormalities in capsular otosclerosis with hydrops Johnsson LG Hawkins JE Jr Rouse RC Linthicum FH Jr Ovid MEDLINE(R) Annals of Otology Rhinology amp Laryngology - Supplement 973-15 1982 Sep-Oct

3 Extensive otosclerosis and endolymphatic hydrops histopathologic study of temporal bones Li W Schachern PA Paparella MM

4 Ovid MEDLINE(R) American Journal of Otolaryngology 15(2)158-61 1994 Mar-Apr Otosclerosis involving the vestibular aqueduct and Menieres disease Yoon TH Paparella MM Schachern PA Ovid MEDLINE(R) Otolaryngology - Head amp Neck Surgery 103(1)107-12 1990 Jul

5 Menieres symptoms resulting from bilateral otosclerotic occlusion of the endolymphatic duct an analysis of a causal relationship between otosclerosis and Menieres disease Franklin DJ Pollak A Fisch U Ovid MEDLINE(R) American Journal of Otology 11(2)135-40 1990 Mar

6 Transtympanic electrocochleography a 10-year experience Otology amp neurotology official publication of the American Otological Society American Neurotology Society (and) European Academy of Otology and Neurotology Otol-Neurotol Sep 2002 vol 23 no 5 p 799-805

7 Cutting edge of inner ear MRI Acta oto-laryngologica Supplementum Acta-Otolaryngol-Suppl Feb 2009 no 560 p 15-21 22 refs ISSN 0365-5237 Naganawa-Shinji Nakashima-Tsutomu

8 Cochlear otosclerosis amp endolymphatic hydrops Otology amp Neurotology 2008 29(4)571-572 A Makarem FH Linthicum

9 The effect of stepedectomy on hearing of patients with otosclerosis and menierersquos disease American J of Otology 19834323-326

10 Endolymphatic hydrops associated with otosclerosis The American journal of otology Am-J-Otol May 1994 vol 15 no 3 p 348-57 ISSN 0192-9763 Shea-J-J-Jr Ge-X Orchik-D-J

Page 13: Guy’s & St Thomas’ Hospitals, London, UK 28 Politzer ... · Gavin Morrison Guy’s & St Thomas’ Hospitals, London, UK 28th Politzer Society, Athens, 28 Sept – 1 October 2011

Endolymphatic Hydrops occurs secondary to Otosclerosis in about 8 cases presenting for treatment

If the history is suggestive ndash Undertake ECOG

Avoid Stapes Surgery with genuine active hydrops

Post-operative Hydrops can develop due to fistulization ndash if so seal it

Delayed Post-op hydrops is also described and requires conservative management

1 Otosclerosis associated with Meacuteniegraveres disease a histological study Advances in oto-rhino-laryngology Adv-Otorhinolaryngol 2007 vol 65 p 50-2 ISSN 0065-3071 Pollak-Anita

2 Cochlear and otoconial abnormalities in capsular otosclerosis with hydrops Johnsson LG Hawkins JE Jr Rouse RC Linthicum FH Jr Ovid MEDLINE(R) Annals of Otology Rhinology amp Laryngology - Supplement 973-15 1982 Sep-Oct

3 Extensive otosclerosis and endolymphatic hydrops histopathologic study of temporal bones Li W Schachern PA Paparella MM

4 Ovid MEDLINE(R) American Journal of Otolaryngology 15(2)158-61 1994 Mar-Apr Otosclerosis involving the vestibular aqueduct and Menieres disease Yoon TH Paparella MM Schachern PA Ovid MEDLINE(R) Otolaryngology - Head amp Neck Surgery 103(1)107-12 1990 Jul

5 Menieres symptoms resulting from bilateral otosclerotic occlusion of the endolymphatic duct an analysis of a causal relationship between otosclerosis and Menieres disease Franklin DJ Pollak A Fisch U Ovid MEDLINE(R) American Journal of Otology 11(2)135-40 1990 Mar

6 Transtympanic electrocochleography a 10-year experience Otology amp neurotology official publication of the American Otological Society American Neurotology Society (and) European Academy of Otology and Neurotology Otol-Neurotol Sep 2002 vol 23 no 5 p 799-805

7 Cutting edge of inner ear MRI Acta oto-laryngologica Supplementum Acta-Otolaryngol-Suppl Feb 2009 no 560 p 15-21 22 refs ISSN 0365-5237 Naganawa-Shinji Nakashima-Tsutomu

8 Cochlear otosclerosis amp endolymphatic hydrops Otology amp Neurotology 2008 29(4)571-572 A Makarem FH Linthicum

9 The effect of stepedectomy on hearing of patients with otosclerosis and menierersquos disease American J of Otology 19834323-326

10 Endolymphatic hydrops associated with otosclerosis The American journal of otology Am-J-Otol May 1994 vol 15 no 3 p 348-57 ISSN 0192-9763 Shea-J-J-Jr Ge-X Orchik-D-J

Page 14: Guy’s & St Thomas’ Hospitals, London, UK 28 Politzer ... · Gavin Morrison Guy’s & St Thomas’ Hospitals, London, UK 28th Politzer Society, Athens, 28 Sept – 1 October 2011

1 Otosclerosis associated with Meacuteniegraveres disease a histological study Advances in oto-rhino-laryngology Adv-Otorhinolaryngol 2007 vol 65 p 50-2 ISSN 0065-3071 Pollak-Anita

2 Cochlear and otoconial abnormalities in capsular otosclerosis with hydrops Johnsson LG Hawkins JE Jr Rouse RC Linthicum FH Jr Ovid MEDLINE(R) Annals of Otology Rhinology amp Laryngology - Supplement 973-15 1982 Sep-Oct

3 Extensive otosclerosis and endolymphatic hydrops histopathologic study of temporal bones Li W Schachern PA Paparella MM

4 Ovid MEDLINE(R) American Journal of Otolaryngology 15(2)158-61 1994 Mar-Apr Otosclerosis involving the vestibular aqueduct and Menieres disease Yoon TH Paparella MM Schachern PA Ovid MEDLINE(R) Otolaryngology - Head amp Neck Surgery 103(1)107-12 1990 Jul

5 Menieres symptoms resulting from bilateral otosclerotic occlusion of the endolymphatic duct an analysis of a causal relationship between otosclerosis and Menieres disease Franklin DJ Pollak A Fisch U Ovid MEDLINE(R) American Journal of Otology 11(2)135-40 1990 Mar

6 Transtympanic electrocochleography a 10-year experience Otology amp neurotology official publication of the American Otological Society American Neurotology Society (and) European Academy of Otology and Neurotology Otol-Neurotol Sep 2002 vol 23 no 5 p 799-805

7 Cutting edge of inner ear MRI Acta oto-laryngologica Supplementum Acta-Otolaryngol-Suppl Feb 2009 no 560 p 15-21 22 refs ISSN 0365-5237 Naganawa-Shinji Nakashima-Tsutomu

8 Cochlear otosclerosis amp endolymphatic hydrops Otology amp Neurotology 2008 29(4)571-572 A Makarem FH Linthicum

9 The effect of stepedectomy on hearing of patients with otosclerosis and menierersquos disease American J of Otology 19834323-326

10 Endolymphatic hydrops associated with otosclerosis The American journal of otology Am-J-Otol May 1994 vol 15 no 3 p 348-57 ISSN 0192-9763 Shea-J-J-Jr Ge-X Orchik-D-J


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