MICROBIOLOGY TOPICS

Hand Washing, Hygiene, CGMP, and ScienceScott Sutton

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“Microbiology Topics” discusses various topics in microbiology of practical use

in validation and compliance. We intend this column to be a useful resource for

daily work applications.

Reader comments, questions, and suggestions are needed to help us fulfill

our objective for this column. Please send your comments and suggestions to

column coordinator Scott Sutton at scott.sutton@microbiol.org or journal coordi-

nating editor Susan Haigney at shaigney@advanstar.com.

KEY POINTSThe following key points are discussed in this article:

include appropriately constructed and sourced water supply, soap

62 Journal of GXP Compliance

ME

DIC

Y POINe follow key po are di sed in t article

OIM

Sco t t Su t t o n , C o o r d in a t o r

EVERYONE KNOWS HOW TO WASH HIS OR HER HANDS, RIGHT?

states the following:

cessing, packing, or holding of a drug product shall wear clean clothing appropriate for the duties they

Standard Test Method for Evaluation of the Effectiveness of Health Care Personnel or Consumer Hand Wash Formulations,

in vivo

FACILITIES

hot and cold water, soap or detergent, air driers or

Water

Winter 2010 Volume 14 Number 1 63

, or hold of a dru oduc hall

Personn r Cons er Han ash lations,fo

sinar

ng, par cl ng ppro ia for he du s ey

MICROBIOLO GY TO PIC S

SoapThe type of soap, and in particular the design of the

and the other choice of lifting the lid and topping it

Antibacterial Additives

with a particular soap containing triclosan, the use

HAND JEWELRY

64 Journal of GXP Compliance

Sco t t Su t t o n , C o o r d in a t o r

wearing a single plain ring (rather like the wedding

in Enterbacteriacae

DRYING

hot air driers and paper towels for the potential to

that these continuous cloth towels are laundered and

Winter 2010 Volume 14 Number 1 65

paper els for th otentiadriers ot air d

MICROBIOLO GY TO PIC S

TRAINING AND MONITORING

supplying a teaching resource for hand washing that includes a lesson outline and three separate sources

A SUGGESTED HAND WASHING PROTOCOL

66 Journal of GXP Compliance

Sco t t Su t t o n , C o o r d in a t o r

dispenser that is refilled in a sealed container

IMPLICATIONS FOR COMPLIANCE

HAND SCRUBS

SUMMARY

Winter 2010 Volume 14 Number 1 67

MICROBIOLO GY TO PIC S

REFERENCES

Virology

Sci Amer.,

Clin Infect Dis,

Amer J

Infect Control

Ind J Dent Res

Serratia marcescens in a

J Hosp Infect.

Serratia marcescens

Infect Control Hosp Epidemiol

Clinical Infectious Diseases

Clin Microbiol Rev,

Appl Envir Microbiol

Opinion of the Scientific Committee on

Cosmetic Products and Non-Food Products Intended for Consum-

ers

Serratia marcescens

Infect Control Hosp Epidem

JSPN,

Infect Control Hosp Epidemiol,

Infect Control Hosp Epidemiol

J Hosp Infect.,

Catering and Health

J Hosp Infect

Amer

J Infect Control

Epidemiol Infect

Infect Control Hosp Epidemiol

Intl J

Infect Dis,

68 Journal of GXP Compliance

nfect Con osp Epid

irology

Inf C ro Hosp pidem ol

,

J Hosp Infect.,

Sco t t Su t t o n , C o o r d in a t o r

J Hosp Infect.,

J Hosp Infect.,

J Adv Nursing

Nurse Education

Today,

Amer J Infect Control

J Hosp Infect.

J Hosp Infect.

Controlled

Environ GXP

ARTICLE ACRONYM LISTINGASTM American Society for Testing and Materials

CDC Centers for Disease Control

CFR Code of Federal Regulations

CGMP Current Good Manufacturing Practice

EC European Commission

EDTA Ethylendiaminetetraacetic Acid

GMP Good Manufacturing Practice

prEN Preliminary European Norm

SOP Standard Operating Procedure

UV Ultraviolet

ABOUT THE AUTHOR

Winter 2010 Volume 14 Number 1 69