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High-Resolution Chest CT:Practical Clinical Applications
Paul L. Molina, M.D.
Department of Radiology
University of North Carolina at Chapel Hill
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Disclosures
None
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Objectives
Identify current clinical indications
for the use of HRCT
Review proper technique forperformance of HRCT
Summarize the characteristic
patterns of abnormality seen on
HRCT and the most common
diseases resulting in their formation
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HRCT - Indication
Evaluation of patients with
suspected infiltrative lung
disease but normal or
nonspecific findings on CXR
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HRCT - Indication
Further characterization ofknown or suspected diffuse
lung disease
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HRCT - Indication
Evaluation of patients in whom
radiographic findings are not
in keeping with clinical findings
or pulmonary function tests
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HRCT - Indication
Delineation of disease prior to
lung biopsy as a guide to the
optimal type and site of biopsy
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HRCT Technique
Thin collimation (1 mm)
High spatial frequency reconstruction Windows -700/1000-1500 HU
Prone scansdifferentiate atelectasis Expiratory scansair trapping
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HRCT Findings
Septal thickening
Reticular densities Nodules
Increased lung opacity
Decreased lung opacity
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Septal Thickening
Pulmonary edema
Lymphangitic carcinomatosis Sarcoidosis
Asbestosis
Idiopathic pulmonary fibrosis
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Reticular Densities
Idiopathic pulmonary fibrosis
Collagen vascular disease
Asbestosis
Chronic hypersensitivity pneumonitis
Sarcoidosis
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UIP
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Nodular Opacities
Sarcoidosis
Silicosis
Coal workers pneumoconiosis
Hypersensitivity pneumonitis
Tuberculosis
Metastatic disease
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Nodular Opacities
Perilymphatic nodules
Random distribution
Centrilobular nodules
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Perilymphatic Nodules
Sarcoidosis
Silicosis
Lymphangitic Ca
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Silicosis
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Random Nodules
Miliary TB
Hematogenous mets
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Metastatic adenoca
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Centrilobular Nodules
Endobronchial spread of TB
or other infection
Hypersensitivity pneumonitis
Endobronchial tumor spread
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Nodular Opacities
Perilymphatic nodules
Random distribution
Centrilobular nodules
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Increased Lung Opacity
Ground-glass opacity
Air-space consolidation
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Ground-glass Opacity
Hypersensitivity pneumonitis (subacute)
Desquamative interstitial pneumonitis Non-specific interstitial pneumonitis
Sarcoidosis Alveolar proteinosis
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DIP
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Non-specific Interstitial Pneumonitis
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Crazy-Paving
Alveolar
Proteinosis
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M i P f i
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Mosaic Pefusion
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Consolidation
Obscures underlying vessels
Solid, opaque
Air bronchograms
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Consolidation
Chronic eosinophilic pneumonia
BOOP / COP
Bronchoalveolar cell carcinoma
Lymphoma
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Chronic Eosinophilic Pneumonia
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BOOP / COP
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Decreased Lung Opacity
Emphysema
Cystic airspaces
Mosaic perfusion
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Cystic Airspaces
Lymphangioleiomyomatosis (LAM)
Langerhans Cell Histiocytosis (EG)
End-stage (honeycomb) lung
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LAM
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EG
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EG
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HRCT - Indications
Suspected infiltrative disease but
normal or nonspecific CXR
Further characterize diffuse disease
CXR findings not in keeping with
clinical findings or PFTs
Guide type and site of biopsy
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HRCT Findings
Septal thickening
Reticular opacities
Nodular opacities
Increased lung opacity Decreased lung opacity