Human embryonic stem cells

Human induced pluripotent stem cells

Yamanaka S. et al. Cell 2007Thomson J. et al. Science 2007

Proteomic comparison

14 days of analysis15,091 phosphorylation sites7,962 unique proteins

Multiplexed enrichment analysis

Chromatin Modifying Proteins

Note reversed scale

Protein-protein interactions

Protein-protein interactions

Becker, KA. et al Journal of Cellular Physiology 2007

Reprogramming networks

Cyclin-dependent kinase 2

mRNA up , protein down

Kinase Analysis