iGEM and The Registry
Synthetic Biology Genopole Randy Rettberg, Dec. 16, 2010
iGEM Schedule: Assemble Your Team
5 High School Students5 Undergraduate Students3 Graduate Students3 Faculty
Utah State - iGEM 2009
iGEM Schedule: Raise Money
iGEM Schedule: Attend A Workshop
iGEM Schedule: Get the BioBrick Parts
iGEM Schedule: Work At Your School
iGEM Schedule: Attend the Jamboree
iGEM Schedule: Attend the Jamboree
iGEM Schedule: Win Awards
Creating a Red Blood Cell Substitute
ResearchersArthur Yu • Austin Day • David Tulga • Hannah Cole • Kristin Doan • Kristin Fuller • Nhu Nguyen • Samantha Liang • Vaibhavi Umesh • Vincent Parker
Teaching AssistantsAmin Hajimorad • Farnaz Nowroozi • Rickey Bonds
AdvisorsJohn Dueber • Christopher Anderson • Adam Arkin • Jay Keasling
Medical Applications
UC Berkeley iGEM 2007
Save the World - Arsenic Detector
A test tube could contain all the necessarycomponents: Freeze dried bacteria, growth
medium,indicator powder, Ampicillin salt, etc…•These tubes could then be
given to local villagers to monitor their own water quality themselves
•A good alternative to the widely used Gutzeit method
www.Macteria.co.uk
Live Forever - BioBeer - Resveratrol
2009 Winner - Cambridge
Is iGEM Safe?
Is iGEM Secure?
iGEM Sites
Europe Almost Always Wins
20102009 2008 2007 2006
Slovenia Cambridge Slovenia Peking Slovenia
BCCS-Bristol Freiburg Caltech UC Berkeley Imperial
Cambridge Groningen NYMU Taipei Slovenia Princeton
Imperial Heidelberg Freiburg Paris
Peking Imperial HarvardUC San
Francisco
TUDelft Valencia UC Berkeley USTC China
Community Parts Collection
Registry DNA Distribution
iGEM Philosophy
Get and Give
Teams are expected to use the parts, ideas, and experience of teams in previous years.
Teams are expected to contribute their parts, ideas, and experiences.
Community Beyond iGEM
iGEM Statistics
• 7,362 users• 2,975 users have logged in this year• 1,189 have entered parts• 118 labs registered
• 14,959 part entries in the Registry• 7,172 samples in the Repository• 2,924 parts reported to work• 1,837 samples sent by iGEM 2010 teams• 800 confirmed DNA (of 1000) in 2010
distribution
iGEM Growth and Scale
25% Growth Projected
Year Teams Attendance
IAP 4 20
2004 5 70
2005 13 130
2006 32 320
2007 54 540
2008 84 840
2009 112 1,120
2010 130 1,300
2011 165 1,650
2012 205 2,050
2013 250 2,500
2014 320 3,200
2015 400 4,000
04 05 06 07 08 09 10 11 12 13 14 15
Regional Structure 2011
World Championship
Jamboree
30 Judges
Asian Jamboree
30 Judges
Americas Jamboree
32 Judges
European Jamboree
30 Judges
The TTL Data Book
The Registry of Standard Biological Parts
Web of Registries
Peking
iGEM HeadquartersGenopole
SB CorpImperial
SynBERC
What we want
Syn-Bio-Co 1 Syn-Bio-Co 2 Public Data School 1 Lab 1
ToolTool
Tool Tool
ToolViewer
ViewerViewer
How can the interfaces be developed?
XML Part Output
Ajax-Based Editing
Device – A ‘Black Box’
Synthetic Biology Question
Can simple biological systems be built from standard, interchangeable parts and operated in living cells?
Or, is biology so complex that each case is unique?
Synthetic Biology Question
Can simple biological systems be built from standard, interchangeable parts and operated in living cells?
Sometimes !
Or, is biology so complex that each case is unique?
Not always!
iGEM and The RegistryQuestions?
Engineering Products –Apple Quadra 840AV
“Ahead of its time, the 840AV and its relative, the Centris/Quadra 660AV, were the first Macintoshes to include 16-bit 48KHz stereo audio recording capability, as well as S-Video and Composite video input and output. They were also the first personal computers that supported speech recognition (PlainTalk) out-of-the-box.”