Importance of Vitamin D

Where is your level at on the scale?

Presented by Andrea FennellKaplan University

HW499April 18, 2011

Introduction

Vitamin D OverviewMedical Importance Are you deficient?Reasons many are deficientVideo discussing Chronic disease prevention Vitamin D and Cancer Role in Heart Disease

Vitamin D Overview Steroid – structured hormone

Is produced photochemcically or consumed via dietary or supplementation

Fat Soluble/found naturally but not in many foods

Exists in 2 forms that matter to humans: Vitamin D2 & Vitamin D3

Can be obtained from sun exposure(sunlight produces syntheisis)

Needed for bone growth/cell growth/ proper immune function

Reduces inflammation

Ruxton, C. H., & Derbyshire E. (2009). Health impacts of vitamin  D: are we getting enough? Nutrition Bulletin, 34 (issue 2), 185-197. Retrieved from http://web.ebscohost.com.lib.kaplan.edu/ehost/detail?vid=15&hid=15&sid=abb95248-5822-4a78-864e-600e6e40a877%40sessionmgr115&bdata=JnNpdGU9ZWhvc3QtbGl2ZQ%3d%3d#db=aph&AN=40120409

Medical ImportanceWhy we should maintain adequate levels

Less chance of Cancers Decreased Cardiovascular Disease Better Osteoarthritis/Skeletal Health Less Falls in Seniors Lowered Autoimmune Disease risks Decrease in Diabetes Type 1 & Type 2 Reduces inflammation Less risks in Pregnancy Must supplement with Lactation

Avalier, E., & Delanaye, P., & Chapelle, J., Souberbielle J. (2009). Vitamin  D current status and perspectives. Clinical Chemistry & Laboratory Medicine, 47(2), 120-127. Retrieved from http://web.ebscohost.com.lib.kaplan.edu/ehost/detail?vid=17&hid=15&sid=abb95248-5822-4a78-864e-600e6e40a877%40sessionmgr115&bdata=JnNpdGU9ZWhvc3QtbGl2ZQ%3d%3d#db=aph&AN=36354806

Are you Deficient? nmol/L** ng/mL* Health status

<30 <12

Associated with vitamin D deficiency, leading to rickets in infants and children and osteomalacia in adults

30–50 12–20Generally considered inadequate for bone and overall health in healthy individuals

≥50 ≥20Generally considered adequate for bone and overall health in healthy individuals

>125 >50 Emerging evidence links potential adverse effects to such high levels, particularly >150 nmol/L (>60 ng/mL)

Office of Dietary Supplement National Institutes of Health Fact Sheet: Vitamin D. Retrieved from http://ods.od.nih.gov/factsheets/VitaminD-HealthProfession

Video: Vitamin & Prevention of Chronic Disease

Speaker is Michael F. HolickPHD, MD from Boston University

http://www.youtube.com/watch?v=Cq1t9WqOD-0&feature=related

Discussion post video

Role in Heart Disease

Framingham Heart Study has reinforced the idea that vitamin D is good for the heart (study conducted over a 30 year period)

1,700 middle-aged men chosen initially w/o heart disease. Those with low vitamin D levels were more likely to develop cardiovascular problems

Those with normal vitamin D levels were less likely to have heart disease

Vitamin D deficiency and risk of cardiovascular diseasehttp://www.ncbi.nlm.nih.gov/pubmed/18180395

Vitamin D & Cancer

Breast

Prostate/Ovarian

Colon Pancreas

Lung

Epidemiologic data suggest that vitamin D status could affect cancer risk

National Cancer Institute Fact Sheet (2011). Vitamin D and Cancer Prevention: Strengths and Limits of the Evidence Retrieved from http://www.cancer.gov/cancertopics/factsheet/prevention/vitamin-D

Conclusion

Vitamin D is just not to needed to make bones stronger. It is a hormone that does many things in tissues to different parts of the body.The new ongoing evidence is that vitamin D has numerous benefits . Are you deficient? If you are not sure ask you health provider to check your levels. New research is linking low vitamin D levels with many disease don’t put your health at risk.

RESOURCESAvalier, E., & Delanaye, P., & Chapelle, J., Souberbielle J.

(2009). Vitamin  D current status and perspectives. Clinical Chemistry & Laboratory Medicine, 47(2), 120-127. Retrieved from http://web.ebscohost.com.lib.kaplan.edu/ehost/detail?vid=17&hid=15&sid=abb95248-5822-4a78-864e-600e6e40a877%40sessionmgr115&bdata=JnNpdGU9ZWhvc3QtbGl2ZQ%3d%3d#db=aph&AN=36354806

Miller J., & Gallo R. L. (2010). Vitamin  D and innate immunity.  Dermatologic Therapy, 23, 13-22. Retrieved from http://web.ebscohost.com.lib.kaplan.edu/ehost/detail?vid=25&hid=15&sid=abb95248-5822-4a78-864e-600e6e40a877%40sessionmgr115&bdata=JnNpdGU9ZWhvc3QtbGl2ZQ%3d%3d#db=aph&AN=47657480

RESOURCES COUNTINUED

National Cancer Institute Fact Sheet (2011). Vitamin D and Cancer Prevention: Strengths and Limits of the Evidence Retrieved form http://www.cancer.gov/cancertopics/factsheet/prevention/vitamin-D

Office of Dietary Supplement National Institutes of Health Fact Sheet: Vitamin Retrieved from http://ods.od.nih.gov/factsheets/VitaminD-HealthProfession

Ruxton, C. H., & Derbyshire E. (2009). Health impacts of vitamin  D: are we getting enough? Nutrition Bulletin, 34 (issue 2), 185-197. Retrieved from http://web.ebscohost.com.lib.kaplan.edu/ehost/detail?vid=15&hid=15&sid=abb95248-5822-4a78-864e-600e6e40a877%40sessionmgr115&bdata=JnNpdGU9ZWhvc3QtbGl2ZQ%3d%3d#db=aph&AN=40120409

Questions and answers